toxic meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Light enhanced cytotoxicity and antitumoral effect of a ruthenium-based photosensitizer inspired from natural alkaloids By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00600C, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Gennaro Sanità, Maria Laura Alfieri, Barbara Carrese, Serena Damian, Vincenza Mele, Gaetano Calì, Brigida Silvestri, Sebastiano Marra, Susan Mohammadi, Giuseppina Luciani, Paola Manini, Annalisa LambertiBiological assays carried out on melanoma and breast cancer cells highlighted the role of light in boosting the cytotoxic effect of a ruthenium complex featuring a dihydroisoquinoline ligand suggesting applications in photodynamic therapy.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Toxic air chokes urban India By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 18:59:29 +0530 Residents grapple with respiratory, cardiac, and other ailments as the air thickens Full Article Pulse
toxic Several Delhi govt. schemes to tackle toxic air yet to take off By www.thehindu.com Published On :: Tue, 05 Nov 2024 03:07:30 +0530 AAP govt. yet to implement at least 5 programmes it announced over the past two years to curb air pollution; these include using drones to map bad air sources and making PUC mandatory to buy fuel; our plans have been stopped by Centre: AAP Full Article Delhi
toxic Delhi enveloped in toxic haze, AQI in severe zone in some areas By www.thehindu.com Published On :: Tue, 05 Nov 2024 10:58:46 +0530 Data from the CPCB's Sameer app, which provides hourly AQI updates, showed that out of the 38 monitoring stations, 13 were in the severe category with readings above 400 Full Article Delhi
toxic Chhath Puja: Devotees take dip in Yamuna even as toxic foam floats over river By www.thehindu.com Published On :: Wed, 06 Nov 2024 00:35:50 +0530 Full Article Delhi
toxic Yamuna highly toxic, says Delhi HC, bins plea to allow Chhath Puja rituals on riverbanks By www.thehindu.com Published On :: Thu, 07 Nov 2024 01:08:00 +0530 Court dismisses petition against order prohibiting Chhath Puja rituals on Yamuna’s banks, says it can’t let devotees fall sick; have made ample arrangements at 1,000 ghats: Delhi govt. counsel; 4-day festival dedicated to Sun God began on Tuesday Full Article Delhi
toxic Trump’s toxic politics of misinformation By www.thehindu.com Published On :: Thu, 24 Oct 2024 01:30:12 +0530 The danger of Donald Trump’s leadership lies in his willingness to exploit and manipulate information to achieve his goals Full Article Comment
toxic Newly synthesized sulfonamide derivatives explored for DNA binding, enzyme inhibitory, and cytotoxicity activities: a mixed computational and experimental analyses By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35047-35063DOI: 10.1039/D4RA06412G, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nasima Arshad, Yasir Mehmood, Hammad Ismail, Fouzia Perveen, Aneela Javed, Pervaiz Ali Channar, Aamer Saeed, Sadia Naseem, Fatima NaseerThis work reports synthesis, characterization, DNA, enzyme binding and cytotoxicity activity of three 4-((3-arylthiazolo[3,4-d]isoxazol-5-yl)amino)benzene sulfonamide derivatives with a thaizaole(3,4-d)isoxazole-based fused ring heterocyclic system.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Bisphenol A (BPA) toxicity assessment and insights into current remediation strategies By pubs.rsc.org Published On :: RSC Adv., 2024, 14,35128-35162DOI: 10.1039/D4RA05628K, Review Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Joshua O. Ighalo, Setyo Budi Kurniawan, Banlambhabok Khongthaw, Junaidah Buhari, P. K. Chauhan, Jordana Georgin, Dison Stracke Pfingsten FrancoTo mitigate the toxic effects of BPA, there is a need to utilize hybrid remediation strategies for its removal from the aqueous environment.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Coinage metal(I) clusters supported by a 1,10-phenanthroline-phosphine: orange-to-NIR phosphorescence, metallophilic interactions and enhanced cytotoxicity By pubs.rsc.org Published On :: Dalton Trans., 2024, 53,18027-18036DOI: 10.1039/D4DT02642J, PaperAlexander V. Artem'ev, Maria P. Davydova, Lyubov S. Klyushova, Evgeniy H. Sadykov, Mariana I. Rakhmanova, Taisiya S. SukhikhBased on 2-(diphenylphosphino)-1,10-phenanthroline, a series of small metal(I) clusters, exhibiting orange to NIR phosphorescence and strong dose-dependent cytotoxicity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Antigenotoxic and cosmetic potential of elderberry (Sambucus nigra) extract: protection against oxidative DNA damage By pubs.rsc.org Published On :: Food Funct., 2024, 15,10795-10810DOI: 10.1039/D4FO03217A, PaperSara Gonçalves, Francisco Peixoto, Tayse F. F. da Silveria, Lillian Barros, Isabel GaivãoThe integrity of the genome is under constant threat from both endogenous and exogenous factors that induce oxidative stress and accelerate ageing.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic FIR filed against producers of Yash-starrer Toxic By www.thehindu.com Published On :: Wed, 13 Nov 2024 06:58:00 +0530 Full Article Bengaluru
toxic Unexpected link between nickel toxicity, cholesterol levels found By www.thehindu.com Published On :: Tue, 05 Nov 2024 05:30:00 +0530 In a new study, fungi that lacked the Sre1 protein were found to be highly sensitive to nickel; the gene that encodes for this protein is conserved in all animals, including humans Full Article Science
toxic Synthesis, Characterization, Genotoxicity Assessment and Antibacterial Applications of Zanthoxylum armatum Silver Nanoparticles (ZASNP) with Antibiotic Efficacy Enhancement Potential By pubs.rsc.org Published On :: Nanoscale, 2024, Accepted ManuscriptDOI: 10.1039/D4NR03608E, Paper Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Nikita Quadri, Manjunath M. Setty, Anshumali Awasthi, Usha Yogendra Nayak, Minakshi Singh, Sharad SharmaThe study aimed to develop alternative antibacterial treatments by combining traditional herbal knowledge with modern nanotechnology. This approach targets multiple bacterial strains, combats antibiotic resistance, and offers solutions for treating...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity By pubs.rsc.org Published On :: Biomater. Sci., 2024, Advance ArticleDOI: 10.1039/D4BM00159A, PaperShulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng QiuBreast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
toxic Oil and gas wastewater is a cheap fix for road dust but comes at a toxic cost By cen.acs.org Published On :: 21 Jun 2018 17:36:42 +0000 Treating roads with the wastewater may pollute the environment with radium and oil and gas compounds Full Article
toxic Oil and gas wastewater is a cheap fix for road dust, but it comes at a toxic cost By cen.acs.org Published On :: 23 Jun 2018 13:13:00 +0000 Treating roads with wastewater may pollute the environment with radium Full Article
toxic Big data mining predicts toxicity better than animal tests By cen.acs.org Published On :: 13 Jul 2018 15:30:00 +0000 Full Article
toxic Chemical toxicity assessments by U.S. EPA to be reshaped, if bill passes By cen.acs.org Published On :: 25 Jul 2018 22:24:24 +0000 Congressional committee votes to give industry and other agencies greater input and to shift responsibility for IRIS program from research office Full Article
toxic Poisonous lands: Pennsylvania prison built next to toxic dump By america.aljazeera.com Published On :: 2016-02-25T10:00:00Z Prisoners and area residents are hit by toxic fumes that could cause fatal harm Full Article
toxic Consensus document on composition of new soybean varieties: food and feed nutrients, anti-nutrients, toxicants and allergens By www.oecd.org Published On :: Fri, 01 Feb 2013 13:15:00 GMT This revised document supplies basic information (compositional considerations, key constituents), useful in risk/safety assessment of food and feed using new varieties of soybean (Glycine max.). This updated publication replaces the original issue of 2001. Full Article
toxic Predicting genetic toxicity with the QSAR Toolbox By www.oecd.org Published On :: Thu, 11 Jul 2013 16:34:00 GMT 11/07/2013 –Recently the OECD released the third generation of the QSAR Toolbox. For this purpose, the guidance document for grouping chemicals to fill data gaps for genetic toxicity and genotoxic carcinogenicity have been updated. This guidance document should support the user of the QSAR Toolbox to build categories that are mechanistically and structurally robust. Full Article
toxic Predicting aquatic toxicity with the QSAR Toolbox By www.oecd.org Published On :: Thu, 11 Jul 2013 16:36:00 GMT 11/07/2013 –Recently the OECD released the third generation of the QSAR Toolbox. For this purpose, the guidance document for grouping chemicals to fill data gaps for acute aquatic toxicity have been updated. This guidance document should support the user of the QSAR Toolbox to build categories that are mechanistically and structurally robust. Full Article
toxic Consensus document on compositional considerations for new varieties of oyster mushroom (Pleurotus ostreatus): Key food and feed nutrients, anti-nutrients and toxicants By www.oecd.org Published On :: Tue, 19 Nov 2013 14:41:00 GMT This document supplies basic information useful in the risk and safety assessment of food and feed using new varieties of oyster mushroom: compositional considerations, key constituents (nutrients, anti-nutrients and toxicants). It is issued in the Novel Food and Feed Safety Series. Full Article
toxic Ecotoxicology and Environmental Fate of Manufactured Nanomaterials: Test Guidelines By www.oecd.org Published On :: Fri, 07 Mar 2014 09:41:00 GMT This document includes the conclusions and recommendations resulting from a workshop that addressed the ecotoxicology and environmental fate of manufactured nanomaterials, and in particular the applicability of existing OECD Test Guidelines (TG) related to these topics. A number of TG developments are underway at OECD as a follow-up to these recommendations. Full Article
toxic Developmental neurotoxicity: OECD/EFSA experts discuss non-animal test methods By www.oecd.org Published On :: Tue, 18 Oct 2016 14:54:00 GMT Participants from 15 countries attended the Workshop on Developmental Neurotoxicity: The use of non-animal test methods for regulatory purposes” on 18 October 2016, in Belgium. The event, co-organised by the OECD and the European Food Safety Authority (EFSA), focused on opportunities and challenges related to alternative methods for testing and assessing the DNT potential of chemicals. Full Article
toxic Adverse Outcome Pathways, Molecular Screening and Toxicogenomics By www.oecd.org Published On :: Mon, 19 Aug 2019 17:16:00 GMT Latest releases: AOPs are the central element of a toxicological knowledge framework, promoted by member countries through OECD, built to support chemical risk assessment based on mechanistic reasoning. Seven New AOPs have now been published. Full Article
toxic BRITs 2020: Maya Jama shares hilarious post about her 'toxic ex' on social media By www.dailymail.co.uk Published On :: Sun, 23 Feb 2020 15:28:49 GMT Maya Jama partied up a storm at the Warner music afterparty at the Chiltern Firehouse on Tuesday night, where her ex, Stormzy was also in attendance. Full Article
toxic Super-rich are fleeing the UK with billions due to George Osborne's 'toxic' tax policies By www.dailymail.co.uk Published On :: Sat, 10 Aug 2019 11:12:01 GMT The number of non-doms, people who are not legally domiciled in the UK but enjoy tax advantages, fell from 98,500 to 78,300 last year, a record low. The tax they contributed also dropped by £2billion. Full Article
toxic Toxic methylmercury-producing microbes more widespread than realized By insider.si.edu Published On :: Fri, 13 Sep 2013 12:29:04 +0000 Microbes that live in rice paddies, northern peat bogs and other previously unexpected environments are among the bacteria that can generate highly toxic methylmercury, researchers […] The post Toxic methylmercury-producing microbes more widespread than realized appeared first on Smithsonian Insider. Full Article Marine Science Research News Science & Nature conservation conservation biology Smithsonian Environmental Research Center
toxic Toxicity of mercury hot spots can be reduced with application of activated carbon, researchers discover By insider.si.edu Published On :: Fri, 25 Oct 2013 12:02:40 +0000 Hot spots of mercury pollution in aquatic sediments and soils can contaminate local food webs and threaten ecosystems, but cleaning them up can be expensive […] The post Toxicity of mercury hot spots can be reduced with application of activated carbon, researchers discover appeared first on Smithsonian Insider. Full Article Marine Science Research News Science & Nature Chesapeake Bay conservation conservation biology materials science pollution Smithsonian Environmental Research Center
toxic Survey pinpoints where toxic mercury accumulates in world environments By insider.si.edu Published On :: Fri, 09 Oct 2015 18:02:40 +0000 Here’s some good news that should hit you in the gut. A team of scientists searching thousands of environments for bacteria that produce the deadly […] The post Survey pinpoints where toxic mercury accumulates in world environments appeared first on Smithsonian Insider. Full Article Animals Marine Science Research News Science & Nature amphibian biodiversity birds conservation biology fishes Smithsonian Environmental Research Center
toxic National Academies Completes Review of National Toxicology Program’s Draft Monograph on Fluoride and Neurodevelopmental and Cognitive Effects By feedproxy.google.com Published On :: Thu, 05 Mar 2020 05:00:00 GMT Today the National Academies of Sciences, Engineering, and Medicine released its review of the National Toxicology Program’s (NTP) draft monograph Systematic Review of Fluoride Exposure and Neurodevelopmental and Cognitive Health Effects. Full Article
toxic California toxic regulators sue FedEx over handling of hazardous shipments By www.scpr.org Published On :: Thu, 26 Jun 2014 15:34:28 -0700 The Department of Toxic Substances Control is claiming that FedEx Ground has mishandled hazardous materials in packages. ; Credit: Thomas Hawk/via Flickr Molly PetersonState regulators have sued FedEx Ground, claiming the company mishandled hazardous chemicals at facilities throughout California during the last 5 years. An investigation into a fire four years ago in San Diego prompted a wider inquiry into how FedEx handles restricted chemicals in statewide shipping at all of its facilities. Regulators claim FedEx didn’t handle thousands of damaged and hazardous packages properly. The state’s complaint claims FedEx would remove damaged packages from shipping and store them for lengthy periods of time in salvage drums, which were moved from hubs to terminals within the company’s network of facilities. These packages contained goods ranging from insecticides and acids to old batteries and other flammable and toxic materials – pretty small shipments, less than 65 pounds, but investigators say they’ve found problems with more than 20 tons of goods shipped over a 5-year period. Each violation alleged in the state’s lawsuit carries a penalty of up to 25-thousand dollars. In a written statement, FedEx spokeswoman Katie Wassmer says the company "complies with all applicable local, state and federal reporting requirements." The state-court complaint is the latest legal salvo in a dispute among California and local officials and FedEx. Earlier this spring, FedEx sued the DTSC and district attorneys from three cities, including Los Angeles, seeking a declaration that federal law pre-empts California's waste handling laws, and that state officials are incorrectly interpreting laws governing FedEx. "To preserve our rights as a federally-registered motor carrier, FedEx Ground filed suit in federal court" said Wassmer. "We are confident that a thorough review of the regulatory framework through the judicial process will support our position." This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
toxic Product design screening method helps reduce toxic materials in consumer goods By ec.europa.eu Published On :: Thu, 11 Apr 2013 10:00:25 +0100 A recent study has described a simple method to screen the toxicity of materials used in consumer products. Using utility meter products as examples, the study found, for example, that stainless steel and polyvinyl chloride (PVC) had high toxicity potentials and suggests less toxic, but equally effective and priced, alternatives that could be used instead. Full Article
toxic Bacterial genes involved in making toxic methylmercury are identified By ec.europa.eu Published On :: Thu, 25 Apr 2013 11:40:59 +0100 Research into mercury has identified two genes in bacteria that appear to be required for turning the metal into its most toxic form, methylmercury. The study adds to a growing body of research that helps us to understand the transformations that mercury undergoes in the environment and the microbes involved in these transformations. Full Article
toxic Sixteen-year reduction in levels of toxic PAHs in the Elbe River, Saxony By ec.europa.eu Published On :: Thur, 16 Apr 2020 12:33:30 GMT Polycyclic aromatic hydrocarbons (PAHs) are a large group of toxic molecules produced by forest fires, industrial processes and the incomplete combustion of fossil fuels. The airborne particles containing these molecules are often washed into watercourses, where they can persist. This study uses long-term monitoring data from the Elbe river, Saxony, Germany, to show how changes in PAH sources affect both the concentrations of these chemicals and the corresponding environmental risks. The researchers suggest that controlling PAHs is the best prevention of harm to aquatic and human health. Full Article
toxic Toxicity tests improve the assessment of harbour sediment quality By ec.europa.eu Published On :: Thu, 21 Nov 2013 08:53:07 GMT Harbour sediments should be tested for their toxic effects on living organisms in addition to being subject to the chemical, physical and biological tests usually conducted to assess water quality, according to recent research from Portugal. This would provide a better environmental assessment of dredged material to help guide port authorities’ decisions on its disposa Full Article
toxic Waste incinerator health risks: no evidence for toxic metal build-up By ec.europa.eu Published On :: Thu, 11 Nov 2010 13:32:21 GMT Spanish medical and public health researchers have found no clear evidence for increased heavy metal levels in adults living near a recently-built urban solid waste incinerator over two years of operation. Concentrations of lead, chromium and mercury in blood and urine samples taken around the plant were not significantly higher than for populations who lived further away. Full Article
toxic Plastics can concentrate toxic pollutants, endangering marine ecosystems By ec.europa.eu Published On :: Thu, 2 May 2013 13:01:29 +0100 Plastic debris is a serious environmental concern, as a physical pollutant as well as a chemical pollutant when it breaks down in the marine environment. A new study has now shown that plastics can also concentrate other pollutants, with significantly higher concentrations of toxic pollutants adhering to soft, rubbery plastics, rather than hard, glassy plastics. Full Article
toxic Laboratory-scale wetlands remove toxic veterinary drugs from wastewater By ec.europa.eu Published On :: Thu, 20 Jun 2013 12:07:44 +0100 Constructed wetlands can effectively remove veterinary drugs from wastewater, preventing contamination of the environment, research suggests. A recent study has demonstrated that laboratory-scale constructed wetlands were able to remove between 94 and 98% of two commonly used antibiotics from pig farm wastewater. Full Article
toxic <new>How predictable is the biological response to chemical toxicity? By ec.europa.eu Published On :: Mon, 20 Jun 2011 16:43:59 +0100 To assess the impact on ecosystems of chemical contamination in aquatic environments, scientists need to measure not only the concentration of the contaminants, but also the extent to which they can disrupt biological processes at a cellular level in plants and animals and at an ecosystem level. According to a new study, considering these complex inter-relationships in combination will help improve the ecological status of waterways, in line with Water Framework Directive (WFD) commitments. Full Article
toxic Nutrients in streams can mask toxic effects of pesticides on aquatic life By ec.europa.eu Published On :: Thu, 23 Jan 2014 8:12:14 GMT Moderate levels of nitrogen in streams and rivers can make it difficult to assess the effects of pesticides on aquatic wildlife, because nutrients mask the pesticides’ impacts, according to recent research. This highlights the importance of considering nutrient levels when developing measures to protect aquatic ecosystems. Full Article
toxic Fin whales exposed to high levels of potentially toxic microplastics in the Mediterranean Sea By ec.europa.eu Published On :: Thu, 11 Feb 2016 09:12:34 GMT Fin whales (Balaenoptera physalus) are likely being exposed to microplastics and associated toxic additives in the Mediterranean Sea, finds new research. The research analysed levels of microplastics and biological and chemical markers of exposure in whales from the Mediterranean Sea and the comparatively pristine Sea of Cortez, off the coast of Mexico. The results suggest that the vulnerable Mediterranean fin whale may be suffering as a consequence of microplastic pollution. Full Article
toxic Changes in soil carbon, biodiversity and ecotoxicity should be considered when assessing environmental impact of dairy products By ec.europa.eu Published On :: Tues, 19 November 2019 11:23:19 GMT Considering the impact on soil carbon, biodiversity and ecotoxicity is important when assessing the environmental footprint of dairy products, suggests a new study, which explored the impacts of organic and conventional milk production in three types of system established in Western Europe. The study found that organic milk production had a significantly lower impact on ecotoxicity and biodiversity than conventional milk production, and suggests that including soil carbon changes in the assessment would result in greater reductions in the carbon footprint of organic, rather than conventional, milk — in some cases by up to 18%. Full Article
toxic Ecotoxicity studies of nanomaterials urgently needed By ec.europa.eu Published On :: Thu, 14 Jan 2010 14:54:29 GMT A new study by Swiss researchers has attempted to predict nanomaterial concentrations in the environment. However, the researchers say more data on environmental toxicity are needed before we can make accurate assessments of potential environmental risks from nanomaterials. Full Article
toxic Biology as important as chemistry in assessing toxic mixtures By ec.europa.eu Published On :: Tue, 1 Jun 2010 11:14:55 +0100 Researchers have developed the first biology-based model to predict the sub-lethal effects of chemical mixtures on organisms. Sub-lethal effects do not cause death but can damage processes such as growth and reproduction. The model provided accurate predictions of the sub-lethal impacts of a chemical mixture on water fleas. Full Article
toxic New tool accurately predicts toxic effects of chemical mixtures By ec.europa.eu Published On :: Tue, 1 Jun 2010 11:19:22 +0100 A new tool that predicts the effects of complex mixtures in water has shown promising results. It correctly predicted the impacts of toxic mixtures on the model species Daphnia magna, or water fleas, in over 90 per cent of cases. Full Article