When it comes to typing a message, font choice can sometimes add a creative touch to your work, but for mass media formats like newspapers, academic papers, TV and popular web sites, sticking to a legible font is often more important than the flourish of decorative fonts.

The two most abundant CaCO3 polymorphs, calcite and aragonite, are universally recognized for the richness of their morphology to which different twins make relevant contributions. The epitaxial transformation calcite ↔ aragonite has long been debated. While the twinning has been thoroughly treated, the homo-epitaxy occurring within each of these minerals has, inexplicably, been overlooked to date, both experimentally and theoretically. Twinning can be deceptive to the point where it can be mistaken for homo-epitaxy, thus making the proposed growth mechanism in the crystal aggregate wrong. Within the present work, the first aim is a theoretical investigation of the homo-epitaxies among the three {10.4}-cleavage, {01.2}-steep and {01.8}-flat rhombohedra of calcite. Accordingly, the specific adhesion energies were calculated between facing crystal forms, unequivocally showing that the {01.2}/{01.8} homo-epitaxy competes with the generation of both {01.2} and {01.8} contact twins. Secondly, the calculation of the specific adhesion energy was extended to consider homo-epitaxy for the {10.4} rhombohedron. The two-dimensional geometric lattice coincidence has been tried for the {00.1} pinacoidal form as well.

The pandemic has taken a massive toll on people's mental health. But a new report by the U.S. Centers for Disease Control and Prevention confirms what many of us are seeing and feeling in our own lives: The impact has been particularly devastating for parents and unpaid caregivers of adults.

Two-thirds of survey respondents who identified as unpaid caregivers said they experienced mental health challenges during the pandemic, such as symptoms of anxiety or depression, or suicidal thoughts.

Only one-third of people with no caregiving responsibilities reported the same symptoms.

Of the more than 10,000 survey respondents, more than 40% identified as being unpaid caregivers.

"What is striking here is just how widespread unpaid caregiving responsibilities are in the population and how much of a burden and a toll these responsibilities" are having, says Shantha Rajaratnam, a co-author of the study and a psychologist at the Turner Institute of Brain and Mental Health at Monash University in Australia.

The study also found that people who care for both children under 18 and adults — many of them part of the sandwich generation — are faring the worst, with 85% of this group experiencing adverse mental health symptoms.

"It's an extremely important study," says psychologist Dolores Gallagher-Thompson, professor emeritus at Stanford University who has researched family caregivers and their challenges.

The study is the first to document the problems caregivers have experienced during COVID-19, she notes, and underscores "the importance of paying attention to caregiver issues, caregiver mental health" and the need for education and resources to better support them.

The contrast between caregivers and others is stark

The study, part of ongoing research by The COVID-19 Outbreak Public Evaluation (COPE) Initiative, is based on surveys conducted in December 2020 and February-March 2021.

More than half of those who identified as caregivers said they had experienced symptoms of anxiety or depression, or of disorders like PTSD related to the stress and trauma of COVID-19.

A significant number of caregivers said they had contemplated suicide. Nearly 40% reported having passive suicidal thoughts, meaning "wishing that they had gone to bed and didn't wake up," says study co-author Mark Czeisler, a graduate student at Monash University and a research trainee at Brigham and Women's Hospital in Boston.

And more than 30% had seriously considered taking their own life — about five times the number of noncaregivers, the study found.

Across the board, mental health impacts have been more severe for people who care for both children and adults. Half of this group said it had seriously considered suicide in the past month.

The pandemic worsened the challenges caregivers face

Even before the pandemic, being an unpaid caregiver was stressful and associated with a higher risk of mental health issues, says Gallagher-Thompson. The COVID-19 pandemic has made things even harder.

For instance, the pandemic has taken away many formal and informal sources of support for caregivers.

That was the case for Dr. Nicole Christian-Brathwaite. She's a Boston-based child psychiatrist and lives with her husband, her mother, her husband's father and two sons, who are 4 and 6.

Before the pandemic, her father-in-law, who has dementia, went to a day program for seniors with cognitive decline. Her mother, a survivor of breast and lung cancers, went to physical therapy twice a week, doctor appointments and met with friends.

When the pandemic hit, they lost those services and social support — at the same time Christian-Brathwaite and her husband began working from home while taking care of their sons and parents.

Life at home became much more complicated. Her sons developed behavioral problems with the transitions and stresses of the pandemic. Her mother struggled with chronic pain, and was hospitalized during the pandemic. And there were days when her father-in-law was confused, disoriented or aggressive.

"Many days I was walking around on edge waiting for something to happen because our entire setup was so very fragile and vulnerable," says Christian-Brathwaite. "It's been exhausting."

And her mental health has suffered. "I certainly was dealing with insomnia," she says. "I was short tempered. I was more irritable. I didn't have the same tolerance for things."

More support needed to help caregivers cope

The new study highlights the extent to which unpaid caregivers have struggled during the pandemic, says Gallagher-Thompson.

"There are some serious issues here that shouldn't be ignored," she says.

And yet caregivers are often ignored by the health system, which is set up to focus only on patients.

"Family members are rarely asked, 'How does this affect you? What is difficult? How can we help you? How can we support you in being able to carry out your role, your tasks, your responsibilities?'" Gallagher-Thompson says.

As the new study shows, support can make a big difference — respondents who could rely on others for help with caregiving had a lower incidence of mental health symptoms.

So it's important to educate and support caregivers. For example, physicians can start by screening their patients' caregivers for mental health symptoms and provide more resources to those who need it, says Gallagher-Thompson.

Christian-Brathwaite hopes the new study will help physicians recognize that family caregivers are just as important to consider while treating patients.

"We really need to take a step back and look at the village that's around them because our patients can't be successful without having the support from family," she says.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Source: Dr. Douglas Loe 11/05/2024

Leede Financial Inc. analyst Dr. Douglas Loe, in a research report published on November 4, 2024, maintained a Buy rating on Profound Medical Corp. (PROF:NASDAQ; PRN:TSX) with a price target of US$18.00. The report follows Profound's announcement that its TULSA-PRO device will receive a Category One CPT code from the U.S. Centers for Medicare & Medicaid Services (CMS).

Loe highlighted the significance of the reimbursement update, stating, "We have long viewed device-specific U.S. reimbursement codes for TULSA-PRO to be integral to its broader adoption in urology/oncology markets, and today's update thus solidifies TULSA-PRO's status on that theme."

The analyst emphasized the favorable reimbursement rates, noting, "Hospitals/ASCs will be reimbursed at the Medicare average of US$12,992/US$10,728 per procedure. This is sufficient economic incentive in our view to drive TULSA-PRO installed base and procedure volume growth in F2025 and thereafter."

Regarding growth projections, Loe stated, "Our model assumes that consolidated revenue/EBITDA/EPS in F2025 of US$34.9M/(US$3.9M)/(US$0.20/shr), but then lifting substantially on all metrics to US$59.1M/US$14.7M/US$0.10/shr in F2026 and then to US$95.5M/US$38.1M/US$1.05/shr in F2027."

The report highlighted potential strategic interest, with Loe noting, "We expect urology-focused suitors to show tangible interest in Profound as the annual top-line performance approaches US$100M on a run-rate basis, which our model projects by FH227."

Leede Financial's valuation methodology combines multiple approaches. Loe explained, "Our valuation still based on NPV (20% discount rate) and multiples of our F2027 EBITDA/fd EPS forecasts (US$38.1M & US$1.05/shr, respectively), with our EV calculation incorporating FQ224 balance sheet data (cash of US$34.1M, total debt of US$6.0M) and fully-diluted S/O of 26.0M."

The analyst also noted that while F2024 is a transition year, F2025 is expected to be transformative for U.S. TULSA-PRO adoption rates.

In conclusion, Leede Financial's maintenance of its Buy rating and US$18 price target reflects confidence in Profound Medical's growth potential following the favorable reimbursement update. The share price at the time of the report of US$7.35 represents a potential return of approximately 145% to the analyst's target price, highlighting the significant upside potential as the company advances its commercialization efforts.

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Disclosures for Leede Financial Inc., Profound Medical Corp., November 4, 2024

Important Information and Legal Disclaimers Leede Financial Inc. (Leede) is a member of the Canadian Investment Regulatory Organization (CIRO) and a member of the Canadian Investor Protection Fund (CIPF). This document is not an offer to buy or sell or a solicitation of an offer to buy or sell any security or instrument or to participate in any particular investing strategy. Data from various sources were used in the preparation of these documents; the information is believed but in no way warranted to be reliable, accurate and appropriate. All information is as of the date of publication and is subject to change without notice. Any opinions or recommendations expressed herein do not necessarily reflect those of Leede. Leede cannot accept any trading instructions via e-mail as the timely receipt of e-mail messages, or their integrity over the Internet, cannot be guaranteed. Dividend yields change as stock prices change, and companies may change or cancel dividend payments in the future. All securities involve varying amounts of risk, and their values will fluctuate, and the fluctuation of foreign currency exchange rates will also impact your investment returns if measured in Canadian Dollars. Past performance does not guarantee future returns, investments may increase or decrease in value, and you may lose money. Leede employees may buy and sell shares of the companies that are recommended for their own accounts and for the accounts of other clients. Disclosure codes are used in accordance with Policy 3600 of CIRO.

Dissemination All final research reports are disseminated to existing and potential institutional clients of Leede Financial Inc. (Leede) in electronic form to intended recipients thorough e-mail and third-party aggregators. Research reports are posted to the Leede website and are accessible to customers who are entitled to the firm’s research. Reproduction of this report in whole or in part without permission is prohibited. Research Analyst Certification The Research Analyst(s) who prepare this report certify that their respective report accurately reflects his/her personal opinion and that no part of his/her compensation was, is, or will be directly or indirectly related to the specific recommendations or views as to the securities or companies. Leede Financial Inc. (Leede) compensates its research analysts from a variety of sources and research analysts may or may not receive compensation based upon Leede investment banking revenue. Canadian Disclosures This research has been approved by Leede Financial Inc. (Leede), which accepts sole responsibility for this research and its dissemination in Canada. Leede is registered and regulated by the Canadian Investment Regulatory Organization (CIRO) and is a member of the Canadian Investor Protection Fund (CIPF). Canadian clients wishing to effect transactions in any designated investment discussed should do so through a Leede Registered Representative.

U.S. Disclosures This research report was prepared by Leede Financial Inc. (Leede). Leede is registered and regulated by the Canadian Investment Regulatory Organization (CIRO) and is a member of the Canadian Investor Protection Fund (CIPF). This report does not constitute an offer to sell or the solicitation of an offer to buy any of the securities discussed herein. Leede is not registered as a broker-dealer in the United States and is not subject to U.S. rules regarding the preparation of research reports and the independence of research analysts. Any resulting transactions should be effected through a U.S. broker-dealer.

( Companies Mentioned: PROF:NASDAQ; PRN:TSX, )

There is no substitute for dramatic reductions in greenhouse gas emissions to mitigate the negative consequences of climate change, a National Research Council committee concluded in a two-volume evaluation of proposed climate-intervention techniques.

The emerging science of gene drives has the potential to address environmental and public health challenges, but gene-drive modified organisms are not ready to be released into the environment and require more research in laboratories and highly controlled field trials, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably without introducing undesired changes — a criterion that has not yet been met by any genome editing technology, says a new report by an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.’s Royal Society.

Read a new NAE Perspective by Christopher A. Hart, former chair of the National Transportation Safety Board and the founder of Hart Solutions LLC, on whether the time is right for driverless motor vehicles.

Historic legislation has been enacted to boost U.S. competitiveness and security, spur innovation, and make real progress on climate change and human health, said the National Academies’ presidents in a statement. “The National Academies stand ready to mobilize the broader science, engineering, and medical and health communities to help inform and implement solutions.”

Artificial intelligence is just a spoke in the wheel of security – an important spoke but, alas, only one

The National Deep Tech Startup Policy (NDTSP) Consortium had released the draft policy on Jul 31 for public consultation, and sought feedback till September 15.

Sify is one among the leading data center operators with existing installed capacity of 190 MW in 12 centers across 6 cities Mumbai, Noida, Chennai, Bangalore, Hyderabad, Kolkata, Bangalore and two upcoming facilities in Noida and Chennai.

Producers that deliver a combination of the new and familiar will likely pique buyer interest.

Wonder Monday has reimagined cheesecake with just 2g sugar, 3g net carbs, 10g clean protein, and nothing artificial. 

Diamond of California, the century-old producer of “Made for Homemade” specialty nuts, has announced the launch of a new chocolate flavor, of their ready-to-use Nut Pie Crusts, available now on both store shelves nationwide, and online with Amazon. 

Dawn Foods has added three new flavors to its frozen ready-to-finish doughnut product line: Apple Crisp, Birthday Cake, and Cherry.

After the resounding victory by Republicans at all levels of government—local, state and federal—in November, there was some speculation about the posture and tone President Obama might take in his final two years in office.

7UP is bringing a ready-to-drink version of the beloved classic Shirley Temple beverage to retail shelves nationwide this month, for a limited time only and just in time for the holiday season.

New Yorkers gain access to a potent cable TV disruptor via FreeCast Home and the next-gen broadcast standard.

As the new school year approaches, SmartBuyGlasses launches its back-to-school campaign with exclusive offers to help every student succeed in style

Introducing the Zorts Sports COVID-19 liability waiver!

Announcement made at virtual Customer Appreciation event

Unit 112 is 1600 square feet with a restroom and office and 14' bay doors to make for easy shipping and receiving.

"Pause Pain and Wellness Medical Cannabis Clinics certainly are." -- Kirk L. Kinard, DO

Exotic India Art is a renowned e-commerce platform that has been serving its customers all over the globe for decades by offering them a wide range of mesmerizing Home Decor delights.

"When more users are desiring to have smoother PH video streaming offline, VideoHunter also released its brand-new VideoHunter PH Downloader to help download HD PH videos to boost better experience."

Unit 100 has 1200 square feet of space, a restroom, an office and 14' bay door for easy shipping and receiving.

Dedicated Elder Abuse Attorneys Committed to Justice for Palm Desert Seniors

Award-winning broadcasting and pro AV solutions ready for their closeup at RAI Amsterdam.

NetCom Learning will showcase its AI skilling solutions at Microsoft Ignite 2024 in Chicago. The event will highlight the latest advancements in AI, cloud technology, and security, and how these innovations can drive business transformation.

What makes "The Hitchhiker's Guide to ChatGPT" so special? Simple - this book is revolutionizing business and personal life with the power of artificial intelligence and ChatGPT.

New Homes, Amenities & Residents Will Enrich A Vibrant Community

Norma B. Cacique, a licensed nail artist, welcomes you to a session of nail art and pampering at NB Nail Studio. From stunning designs and acrylics to luxurious manicures, this boutique offers everything you need to make your nails stand out.

Score Awesome Finds at Auctions While Making a Positive Impact on Children's Education Futures!

To tap with friends, you have to grab the new trends in the TuneFab YouTube Music Converter. This brand-new music downloader will get you the entire YouTube music world in your offline library with ultimate customization & specifications.

STARBOYS MUSIC will be around for a lifetime!

Applications for the 2024-2025 year will begin to be accepted starting Nov. 1, 2024. To give this chance again to more students, Dr. Kezian is re-launching his scholarship for the upcoming 2024 – 2025 year.

Luvme Hair, a leading brand in the human hair wigs industry, is proud to announce a summer sale from July 9th to July 31st.

Is Your Commercial Roof Ready To Be Replaced?

Above: Front row (left to right): John Featherston, Anthony Lamacchia, Dava Davin; Back row (left to right): Dan Duffy, Al Becker, Wendy Forsythe For innovative brokerage leaders, the twists and turns of 2024 will ultimately lead to one place: A stellar 2025. If you are in the Boston, Massachusetts, area on Friday, don’t miss RISMedia’s…

The post Ready for the Future: The Broker Playbook for a Stand-Out 2025 appeared first on RISMedia.

We all know that the past year has driven innovation throughout the economy. As business conditions shifted in early 2020, innovators across the globe were forced to use any means to keep their organization open. The digital transformation we have seen in our society over the past year is not going away anytime soon, so it’s important for leaders and visionaries...

The post 10 Ways to Automate Business Processes Using a Tool You Already Have: Microsoft Power Platform appeared first on Anders CPA.

Cloud-based BMC Helix and Control-M deliver mission-critical capabilities for today and set up future AI use cases for success

California’s Workers’ Compensation Insurance Rating Bureau and the Oklahoma Workers’ Compensation Commission on Wednesday announced plans to launch new websites. The Oklahoma Workers’ Compensation Commission announced that it will unveil its…

n this session, we will discuss a 15-year-old law that consistently confuses and frustrates responsible reporting entities in our industry.

just a few WordCamp’s that are starting off the new year.

The post Getting ready for WordCamps in 2010 appeared first on WPCult.