End-to-end quality of service for video telephony over 4G mobile networks

40-Gigabit-capable passive optical networks 2 (NG-PON2): Physical media dependent (PMD) layer specification

Simulations of transport of time over packet networks

End-to-end quality of service for voice over 4G mobile networks

Timing and synchronization aspects in packet networks

Modem-over-IP networks: Procedures for the end-to-end connection of V-series DCEs

Procedures for supporting voice-band data over IP networks

Implementers' Guide for Recommendation ITU-T V.152 (Procedures for supporting voice-band data over IP networks)

Procedures for supporting voice-band data over IP networks

Telecoms Bankroll More Misleading Attacks On Community Broadband Networks techdirt.com
Canada's BCE to acquire US internet firm Ziply for $3.6 bln reuters.com
How hackers used infostealer malware to breach AT&T, Ticketmaster, Santander, EA, and more, as global law enforcement tries to shut down the growing industry wired.com
Apple's satellite ambitions get $1.1B bigger lightreading.com
NTIA Announces Approval of Eleven States Digital Equity Capacity Grant Applications telecompetitor.com
T-Mobile plans to use OpenAI's tech for a customer service bot slated for 2025 that can refer to customer-specific data, and will pay $100M over three years theinformation.com
CMA 'provisionally' accepts Vodafone and Three s merger remedies mobileeurope.co.uk
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Huawei’s Kevin McDonnell says autonomous networks can detect issues and make decisions on their own, making them essential for future network operations.

Read more: Autonomous networks are smarter – but not without challenges

The company will use some of the funding to advance its wildfire suppression project, which uses autonomous drones and acoustic waves.

Read more: Dryad Networks raises €6.3m to drive wildfire prevention tech

Canary Speech's Paired Neural Networks Technology is a form of voice biomarker technology that identifies subtle shifts in an individual's voice by analyzing it against previous samples from the same person.

The expanded relationship between the two long-time partners brings NTT DATA’s Managed Extended Detection Response Service onto the Palo Alto Networks XSIAM Cortex platform, to add additional AI capabilities to threat monitoring, detection and rapid response.

Location: Electronic Resource- 

Location: Engineering Library- TK5103.2.D47 2016

Location: Engineering Library- TK5103.2.M49 2016

He tried to find a therapist who would take his insurance. He did not succeed.

Social networks are a great way to introduce people to the power of Sociology. In my Intro class, I make a point to show students the way their social networks shape the spread of divorce, how people ask for help, and the surprisingly tangled world of dating. Now there’s a new take on networks – […]

The U.S. Cybersecurity and Infrastructure Security Agency (CISA) on Thursday added a now-patched critical security flaw impacting Palo Alto Networks Expedition to its Known Exploited Vulnerabilities (KEV) catalog, citing evidence of active exploitation. The vulnerability, tracked as CVE-2024-5910 (CVSS score: 9.3), concerns a case of missing authentication in the Expedition migration tool that

Cybersecurity researchers have flagged a new ransomware family called Ymir that was deployed in an attack two days after systems were compromised by a stealer malware called RustyStealer. "Ymir ransomware introduces a unique combination of technical features and tactics that enhance its effectiveness," Russian cybersecurity vendor Kaspersky said. "Threat actors leveraged an unconventional blend

Montgomery Blencowe
Dec 23, 2020; 0:jlr.RA120000713v1-jlr.RA120000713
Research Articles

Genome-wide association studies (GWAS) have implicated ~380 genetic loci for plasma lipid regulation. However, these loci only explain 17-27% of the trait variance and a comprehensive understanding of the molecular mechanisms has not been achieved. In this study, we utilized an integrative genomics approach leveraging diverse genomic data from human populations to investigate whether genetic variants associated with various plasma lipid traits, namely total cholesterol (TC), high and low density lipoprotein cholesterol (HDL and LDL), and triglycerides (TG), from GWAS were concentrated on specific parts of tissue-specific gene regulatory networks. In addition to the expected lipid metabolism pathways, gene subnetworks involved in ‘interferon signaling’, ‘autoimmune/immune activation’, ‘visual transduction’, and ‘protein catabolism’ were significantly associated with all lipid traits. Additionally, we detected trait-specific subnetworks, including cadherin-associated subnetworks for LDL, glutathione metabolism for HDL, valine, leucine and isoleucine biosynthesis for TC, and insulin signaling and complement pathways for TG. Finally, utilizing gene-gene relations revealed by tissue-specific gene regulatory networks, we detected both known (e.g. APOH, APOA4, and ABCA1) and novel (e.g. F2 in adipose tissue) key regulator genes in these lipid-associated subnetworks. Knockdown of the F2 gene (Coagulation Factor II, Thrombin) in 3T3-L1 and C3H10T1/2 adipocytes reduced gene expression of Abcb11, Apoa5, Apof, Fabp1, Lipc, and Cd36, reduced intracellular adipocyte lipid content, and increased extracellular lipid content, supporting a link between adipose thrombin and lipid regulation. Our results shed light on the complex mechanisms underlying lipid metabolism and highlight potential novel targets for lipid regulation and lipid-associated diseases.

The Discoidin, CUB, and LCCL domain-containing protein (DCBLD) family consists of two type-I transmembrane scaffolding receptors, DCBLD1 and DCBLD2, which play important roles in development and cancer. The nonreceptor tyrosine kinases FYN and ABL are known to drive phosphorylation of tyrosine residues in YXXP motifs within the intracellular domains of DCBLD family members, which leads to the recruitment of the Src homology 2 (SH2) domain of the adaptors CT10 regulator of kinase (CRK) and CRK-like (CRKL). We previously characterized the FYN- and ABL-driven phosphorylation of DCBLD family YXXP motifs. However, we have identified additional FYN- and ABL-dependent phosphorylation sites on DCBLD1 and DCBLD2. This suggests that beyond CRK and CRKL, additional DCBLD interactors may be regulated by FYN and ABL activity. Here, we report a quantitative proteomics approach in which we map the FYN- and ABL-regulated interactomes of DCBLD family members. We found FYN and ABL regulated the binding of several signaling molecules to DCBLD1 and DCBLD2, including members of the 14-3-3 family of adaptors. Biochemical investigation of the DCBLD2/14-3-3 interaction revealed ABL-induced binding of 14-3-3 family members directly to DCBLD2.

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CAMBRIDGE, England, Oct. 15, 2024 — Nu Quantum has announced a proof-of-principle prototype that advances the development of modular, distributed quantum computers by enabling connections across different qubit modalities and […]

The post Nu Quantum Unveils Qubit-Photon Interface to Enable Distributed Quantum Computing Networks appeared first on HPCwire.

Aug. 19, 2024 — SURF’s innovation department recently collaborated with Cornelis Networks to advance networking capabilities for high-performance computing (HPC) clusters. The collaboration marks a new step forward for SURF […]

The post Cornelis Networks Partners with SURF to Enhance HPC Cluster Networking Capabilities appeared first on HPCwire.

Umut Güçlü
Jul 8, 2015; 35:10005-10014
BehavioralSystemsCognitive

Title: Study: Young Adults Who Had Depression Have 'Hyper-Connected' Brain Networks
Category: Health News
Created: 8/27/2014 2:36:00 PM
Last Editorial Review: 8/28/2014 12:00:00 AM

Most studies of genome organization have focused on intrachromosomal (cis) contacts because they harbor key features such as DNA loops and topologically associating domains. Interchromosomal (trans) contacts have received much less attention, and tools for interrogating potential biologically relevant trans structures are lacking. Here, we develop a computational framework that uses Hi-C data to identify sets of loci that jointly interact in trans. This method, trans-C, initiates probabilistic random walks with restarts from a set of seed loci to traverse an input Hi-C contact network, thereby identifying sets of trans-contacting loci. We validate trans-C in three increasingly complex models of established trans contacts: the Plasmodium falciparum var genes, the mouse olfactory receptor "Greek islands," and the human RBM20 cardiac splicing factory. We then apply trans-C to systematically test the hypothesis that genes coregulated by the same trans-acting element (i.e., a transcription or splicing factor) colocalize in three dimensions to form "RNA factories" that maximize the efficiency and accuracy of RNA biogenesis. We find that many loci with multiple binding sites of the same DNA-binding proteins interact with one another in trans, especially those bound by factors with intrinsically disordered domains. Similarly, clustered binding of a subset of RNA-binding proteins correlates with trans interaction of the encoding loci. We observe that these trans-interacting loci are close to nuclear speckles. These findings support the existence of trans-interacting chromatin domains (TIDs) driven by RNA biogenesis. Trans-C provides an efficient computational framework for studying these and other types of trans interactions, empowering studies of a poorly understood aspect of genome architecture.

Neural reflexes occupy a central role in physiological homeostasis. The vagus nerve is a major conduit for transmitting afferent and efferent signals in homeostatic reflex arcs between the body and the brain. Recent advances in neuroscience, immunology, and physiology have revealed important vagus nerve mechanisms in suppressing inflammation and treating rheumatoid arthritis and other autoimmune conditions. Numerous clinical trials indicate that there is significant benefit to vagus nerve stimulation therapy. Although many questions are still unanswered, it will be important, even necessary, to pursue answers that will be useful in guiding interventions to modulate immunological and physiological homeostasis.

ABSTRACTThe private health care sector is an important source of service delivery in low- and middle-income countries (LMICs). Yet, the private sector remains fragmented, making it difficult for health system actors to support and ensure the availability of quality health care services. In global health programs, social franchising is one model used to engage and organize the private health care sector. Two social franchise networks, ProFam in West Africa and Tunza in East and Central Africa, provide health care through branded networks of facilities. However, these social franchise networks include a limited number of private health care facilities, and in fragile contexts, like Burundi and Mali, they have faced challenges in integrating with national health systems. The MOMENTUM Private Healthcare Delivery (MPHD) project in Burundi and Mali sought to expand the number of health facilities it engaged beyond the existing ProFam and Tunza networks. The expansion aimed to help improve service quality in more private facilities while advancing localization and reducing fragmentation for improved stewardship by health system actors. MPHD achieved this expansion by removing barriers for private health facilities to join inclusive, nonbranded networks and engaging local partners to build and maintain these networks. We share lessons learned regarding the growing role of local organizations as actors within mixed health systems and provide insights on strengthening stewardship of the increasingly heterogeneous private health care delivery sector in LMICs, particularly in fragile settings.

Next-generation phone networks could dramatically outperform current ones thanks to a new technique for transmitting multiple streams of data over a wide range of frequencies

Since it was founded in 2015, Cato Networks has evangelized the concept of a Secure Access Service Edge (SASE) platform that combines many of the features of software-defined networking, modern network security tools, and endpoint protection into a single service backed by a global private network. The promise here is that instead of managing dozens […]

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New York, NY : Bloomsbury Academic, 2020.

Turnhout : Brepols, 2023.

London ; New York : Tauris Academic Studies, 2006.

Ithaca, NY : Cornell University Press, [2023]

eSafety Commissioner Julie Inman Grant told Deborah Knight her agency can compel social media companies to remove harmful content which victimises children.

However, we now have more adult cyber abuse reports coming in than we do youth-based cyberbullying reports.

Ms Inman Grant criticised the leadership of social networks for deflecting responsibility onto victims and regulators.