isp Advanced Food Systems: Keep Color, Moisture, Crispiness By www.preparedfoods.com Published On :: Fri, 18 Sep 2020 07:45:00 -0400 Advanced Food Systems offers a variety of specialty pre-coats, and batter systems for meat, poultry, seafood, vegetables and plant-based products. Full Article
isp New Hispanic-Inspired Products to Round Out 2023 By www.preparedfoods.com Published On :: Mon, 04 Dec 2023 05:15:00 -0500 “We were thrilled when Francia approached us with her vision. Her passion to bring to life her grandmother's recipe—inspired by her passion for cooking and experience growing up in Los Angeles—resonated with our own commitment to bringing to consumers the flavors of Mexico raised in LA,” said Diana DeLoza, LA VICTOIA director of marketing. “…Together, we created a salsa that celebrates the rich heritage of Los Angeles and brings it to tables everywhere.” Full Article
isp Disposable boot covers By www.safetyandhealthmagazine.com Published On :: Sun, 24 Jun 2018 00:00:00 -0400 Boot Saver Disposable Covers provide temporary, 100 percent liquid-proof protection and contamination prevention for boots and shoes. Full Article
isp Customizable skin care dispenser By www.safetyandhealthmagazine.com Published On :: Sun, 23 Sep 2018 00:00:00 -0400 Customize different types of skin care dispensers with the updated Pick and Mix website. Full Article
isp Tyson Brand Honey Chicken Bites, Restaurant Style Crispy Wings By www.preparedfoods.com Published On :: Tue, 02 Jul 2024 08:00:00 -0400 Crafted from tender, all-white meat chicken and covered in a honey-infused breading, the bites are designed to delight taste buds and satisfy cravings. Full Article
isp Whisps Protein Snackers By www.preparedfoods.com Published On :: Mon, 13 May 2024 08:00:00 -0400 Whisps Protein Snackers are an on-the-go option that doesn't require refrigeration for snackers looking for something quick, convenient and satisfying. Full Article
isp How Campbell’s Innovated Snacking with Goldfish Crisps By www.preparedfoods.com Published On :: Thu, 31 Oct 2024 00:00:00 -0400 Campbell’s extends popular Goldfish platform with “mash-up” of crackers and potato chips. Full Article
isp Hispanic Consumers Drive 16% of Total US CPG Growth By www.preparedfoods.com Published On :: Fri, 08 Nov 2024 06:45:00 -0500 These reports highlight that Hispanics now make up 20% of the US population and account for 71% of national population growth between 2022 and 2023. More than 25% of Gen Z and Gen Alpha identify as Hispanic, demonstrating the long-term potential of this powerful consumer group. Full Article
isp Beauflor Unveils New Merchandising Displays for Laminate and SPC Collections By www.floortrendsmag.com Published On :: Wed, 23 Aug 2023 00:00:00 -0400 Retailers have a new tower display for Innovius SPC and new step displays for Encompass and Oterra laminate collections. Full Article
isp Hispanic Cheese Makers' fabulous food plant sets the bar for reducing waste By www.foodengineeringmag.com Published On :: Wed, 12 Dec 2018 08:45:00 -0500 What Hispanic Cheese Makers is doing with its wastewater and with its sustainability efforts overall makes it a model for producers looking for ways to be sustainable and good neighbors, and it’s why Hispanic Cheese Makers is being featured as a Fabulous Food Plant. Full Article
isp Trapped Mobility: a theoretical framework and literature review focusing on displaced youth at the borders between the Global South and Global North. By ezproxy.scu.edu.au Published On :: Tue, 01 Feb 2022 00:00:00 -0500 Children's Geographies; 02/01/2022(AN 154441555); ISSN: 14733285Academic Search Premier Full Article LITERATURE reviews INVOLUNTARY relocation DEVELOPING countries
isp Displaced children's experience of places and play: a scoping review. By ezproxy.scu.edu.au Published On :: Thu, 01 Jun 2023 00:00:00 -0400 Children's Geographies; 06/01/2023(AN 164286257); ISSN: 14733285Academic Search Premier Full Article REFUGEE children PLACE attachment (Psychology) THEATER reviews BUILT environment EVIDENCE gaps
isp Adolescents in Humanitarian Crisis. Displacement, Gender and Social Inequalities: Nicola Jones, Kate Pincock, Bassam Abu Hamad (Editors), 2021, Abingdon, New York: Routledge 238 pp., paperback £27.99/e-book open access content, ISBN 978-0-367-76461-6 By ezproxy.scu.edu.au Published On :: Tue, 01 Aug 2023 00:00:00 -0400 Children's Geographies; 08/01/2023(AN 167303416); ISSN: 14733285Academic Search Premier Full Article NEW York (State) EQUALITY ELECTRONIC books TEENAGERS GENDER inequality YOUNG adults INTERNALLY displaced persons
isp Multispecies collaboratories: reconfiguring children's more-than-human entanglement with colonization, urban development and climate change. By ezproxy.scu.edu.au Published On :: Thu, 01 Feb 2024 00:00:00 -0500 Children's Geographies; 02/01/2024(AN 175911766); ISSN: 14733285Academic Search Premier Full Article VICTORIA LONDON (Ont.) URBAN climatology GREEN movement INDIGENOUS peoples RECIPROCITY (Psychology) KINSHIP INDIGENOUS children
isp Hong Kong kindergartens in urban space: policy aspirations, historical trajectories, and contemporary disparities. By ezproxy.scu.edu.au Published On :: Sat, 01 Jun 2024 00:00:00 -0400 Children's Geographies; 06/01/2024(AN 178088787); ISSN: 14733285Academic Search Premier Full Article HONG Kong (China) KINDERGARTEN children PUBLIC spaces URBAN policy KINDERGARTEN facilities KINDERGARTEN URBAN density
isp Children, common bracken and cows at work: re-considering work in multispecies relations through childhood memories. By ezproxy.scu.edu.au Published On :: Thu, 07 Nov 2024 00:00:00 -0500 Children's Geographies; 11/07/2024(AN 180691492); ISSN: 14733285Academic Search Premier Full Article
isp From forced to coerced labour: displaced mothers and teen girls in post-World War II Australia By ifp.nyu.edu Published On :: Thu, 24 Oct 2024 20:37:26 +0000 Volume 64, Issue 3, June 2023. Read the full article › The post From forced to coerced labour: displaced mothers and teen girls in post-World War II Australia was curated by information for practice. Full Article History
isp The Myriad Racial, Ethnic Disparities in Health are Dramatic By ifp.nyu.edu Published On :: Sat, 02 Nov 2024 13:51:48 +0000 The post The Myriad Racial, Ethnic Disparities in Health are Dramatic was curated by information for practice. Full Article Grey Literature
isp Considering Maternal Health Disparities: Proceedings of a Workshop Series—in Brief By ifp.nyu.edu Published On :: Sun, 03 Nov 2024 16:29:31 +0000 The post Considering Maternal Health Disparities: Proceedings of a Workshop Series—in Brief was curated by information for practice. Full Article Grey Literature
isp Conceptualizing bias in EHR data: A case study in performance disparities by demographic subgroups for a pediatric obesity incidence classifier By ifp.nyu.edu Published On :: Mon, 04 Nov 2024 01:32:39 +0000 The post Conceptualizing bias in EHR data: A case study in performance disparities by demographic subgroups for a pediatric obesity incidence classifier was curated by information for practice. Full Article Open Access Journal Articles
isp Behavioral Weight Management Interventions for Hispanic Men in the United States: A Systematic Review By ifp.nyu.edu Published On :: Mon, 04 Nov 2024 23:59:42 +0000 American Journal of Men’s Health, Volume 18, Issue 5, September-October 2024. Hispanic men have the highest prevalence of obesity relative to other racial and ethnic subgroups; however, this population is consistently underrepresented in weight management interventions. This systematic review aims to provide an overview of behavioral weight management interventions adapted for Hispanic men and describe […] The post Behavioral Weight Management Interventions for Hispanic Men in the United States: A Systematic Review was curated by information for practice. Full Article Open Access Journal Articles
isp CfP: Global diversity and disparity in mental health and brain health (Deadline: 1 April) By ifp.nyu.edu Published On :: Tue, 29 Oct 2024 20:31:56 +0000 The post CfP: Global diversity and disparity in mental health and brain health (Deadline: 1 April) was curated by information for practice. Full Article Calls & Consultations
isp Judge blocks Louisiana law requiring display of Ten Commandments in classrooms By www.npr.org Published On :: Wed, 13 Nov 2024 04:17:49 -0500 A federal judge has ruled that a Louisiana law requiring the display of the Ten Commandments in public school classrooms is unconstitutional. Full Article
isp Federal judge blocks Louisiana law that requires classrooms to display Ten Commandments By www.mprnews.org Published On :: Tue, 12 Nov 2024 16:48:08 +0000 The new Louisiana requirement that the Ten Commandments be displayed in every public classroom by Jan. 1 was temporarily blocked Tuesday. The judge said the law is "unconstitutional on its face." Full Article
isp Boeing cleaned up on Air Force parts, including soap dispensers marked up 8,000 percent By www.mprnews.org Published On :: Fri, 01 Nov 2024 11:39:00 +0000 Boeing overcharged the Air Force nearly $1 million for spare parts on C-17 cargo planes, including an 8,000 percent markup for simple lavatory soap dispensers, according to the Pentagon’s inspector general. Full Article
isp NYC church sues Disciples of Christ over $7.3 million loan dispute By www.christianpost.com Published On :: Fri, 08 Nov 2024 10:54:59 -0500 A congregation based in New York City has filed a lawsuit against an entity of the Indiana-based Disciples of Christ, accusing it of refusing to provide $7.3 million in loan funding advances. Full Article
isp Pastor Greg Locke reneges on offer to refund tithes amid church dispute By www.christianpost.com Published On :: Mon, 11 Nov 2024 13:37:00 -0500 After promising to refund the donations of members who questioned the stewardship of his church's finances, outspoken Tennessee Pastor Greg Locke has reneged on that offer. His attorney has allegedly threatened at least one donor who asked for their money back. Full Article
isp Judge blocks Louisiana from displaying Ten Commandments in classrooms By www.christianpost.com Published On :: Tue, 12 Nov 2024 12:35:00 -0500 A federal judge has temporarily blocked a recently passed Louisiana law that would require public school classrooms to display the Ten Commandments. Full Article
isp New dispute resolution Brown Bag Series By www.tdi.texas.gov Published On :: Wed, 16 Nov 2022 00:00:00 CST Deputy Commissioner of Hearings Allen Craddock and his staff will continue a series of meetings with stakeholders in the Texas workers’ compensation system. Participants are invited to bring a lunch for these meetings in this Brown Bag Series. Full Article
isp New DWC ‘Brown Bag Series’ on dispute resolution By www.tdi.texas.gov Published On :: Fri, 23 Aug 2024 00:00:00 CDT This fall DWC Hearings continues their Brown Bag Series with stakeholders in the Texas workers’ compensation system. Full Article
isp UK retailers must look to point of sale and display solutions to reduce retail theft in 2024 By www.retailtechnologyreview.com Published On :: Mon, 13 Nov 8800 17:07:00 +0000 In the ever-evolving landscape of retail, businesses face an ongoing challenge: theft.Despite many retailers implementing additional security measures, the issue of stolen goods continues to plague the industry with beers and wine, health and beauty products, and baby formula being the most common stolen goods. Full Article EPoS Systems Critical Issues
isp PPDS brings more ‘zero power’ choice and opportunity to business with new 13” Philips Tableaux 4150 ePaper displays at InfoComm 2024 By www.retailtechnologyreview.com Published On :: PPDS, the exclusive global provider of Philips Professional Displays and complementary hardware and software solutions, has announced the latest evolution of its multi-award-winning ePaper with Android SoC signage range, launching the new 13” Philips Tableaux 4150 at InfoComm 2024. Full Article Digital Signage Exhibitions and Events
isp PPDS to unveil ‘all inclusive’ suite of hospitality display solutions at EquipHotel 2024 + new global streaming partnership announcement By www.retailtechnologyreview.com Published On :: PPDS is participating at EquipHotel 2024 (3-7 November), with the latest innovations in its portfolio of hospitality display solutions, plus the launch of a brand new ‘all inclusive’ streaming partnership for Philips MediaSuite TVs. Full Article Digital Signage Exhibitions and Events
isp Defense Chiefs of S. Korea, US Condemn Dispatching of N. Korean Troops in ‘Strongest Terms’ By world.kbs.co.kr Published On :: Thu, 31 Oct 2024 08:31:24 +0900 [Inter-Korea] : The defense chiefs of South Korea and the United States have condemned the deployment of North Korean troops to Russia in the “strongest” terms with “one voice.” Defense Minister Kim Yong-hyun and U.S. Secretary of Defense Lloyd Austin issued the condemnation on Wednesday in a joint statement after ...[more...] Full Article Inter-Korea
isp A-roaring display - British Geological Survey By news.google.com Published On :: Thu, 16 May 2024 07:00:00 GMT A-roaring display British Geological Survey Full Article
isp Assessment of the exchange-hole dipole moment dispersion correction for the energy ranking stage of the seventh crystal structure prediction blind test By journals.iucr.org Published On :: 2024-10-15 The seventh blind test of crystal structure prediction (CSP) methods substantially increased the level of complexity of the target compounds relative to the previous tests organized by the Cambridge Crystallographic Data Centre. In this work, the performance of density-functional methods is assessed using numerical atomic orbitals and the exchange-hole dipole moment dispersion correction (XDM) for the energy-ranking phase of the seventh blind test. Overall, excellent performance was seen for the two rigid molecules (XXVII, XXVIII) and for the organic salt (XXXIII). However, for the agrochemical (XXXI) and pharmaceutical (XXXII) targets, the experimental polymorphs were ranked fairly high in energy amongst the provided candidate structures and inclusion of thermal free-energy corrections from the lattice vibrations was found to be essential for compound XXXI. Based on these results, it is proposed that the importance of vibrational free-energy corrections increases with the number of rotatable bonds. Full Article text
isp From formulation to structure: 3D electron diffraction for the structure solution of a new indomethacin polymorph from an amorphous solid dispersion By journals.iucr.org Published On :: 2024-08-28 3D electron diffraction (3DED) is increasingly employed to determine molecular and crystal structures from micro-crystals. Indomethacin is a well known, marketed, small-molecule non-steroidal anti-inflammatory drug with eight known polymorphic forms, of which four structures have been elucidated to date. Using 3DED, we determined the structure of a new ninth polymorph, σ, found within an amorphous solid dispersion, a product formulation sometimes used for active pharmaceutical ingredients with poor aqueous solubility. Subsequently, we found that σ indomethacin can be produced from direct solvent evaporation using dichloromethane. These results demonstrate the relevance of 3DED within drug development to directly probe product formulations. Full Article text
isp Enhancing the Efficiency of a Wavelength-Dispersive Spectrometer based upon a Slit-less Design Using a Single-Bounce Monocapillary By journals.iucr.org Published On :: A slit-less wavelength-dispersive spectrometer design using a single-bounce monocapillary that aligns the sample on the Rowland circle, enhancing photon throughput and maintaining resolution. The compact design supports flexibility and reconfiguration in facilities without complex beamline infrastructure, significantly improving detection efficiency. Full Article text
isp An electropneumatic cleaning device for piezo-actuator-driven picolitre-droplet dispensers By journals.iucr.org Published On :: 2024-02-01 Recently, we introduced the liquid application method for time-resolved analyses (LAMA). The time-consuming cleaning cycles required for the substrate solution exchange and storage of the sensitive droplet-dispenser nozzles present practical challenges. In this work, a dispenser cleaning system for the semi-automated cleaning of the piezo-actuator-driven picolitre-droplet dispensers required for LAMA is introduced to streamline typical workflows. Full Article text
isp Implications of size dispersion on X-ray scattering of crystalline nanoparticles: CeO2 as a case study By journals.iucr.org Published On :: 2024-05-31 Controlling the shape and size dispersivity and crystallinity of nanoparticles (NPs) has been a challenge in identifying these parameters' role in the physical and chemical properties of NPs. The need for reliable quantitative tools for analyzing the dispersivity and crystallinity of NPs is a considerable problem in optimizing scalable synthesis routes capable of controlling NP properties. The most common tools are electron microscopy (EM) and X-ray scattering techniques. However, each technique has different susceptibility to these parameters, implying that more than one technique is necessary to characterize NP systems with maximum reliability. Wide-angle X-ray scattering (WAXS) is mandatory to access information on crystallinity. In contrast, EM or small-angle X-ray scattering (SAXS) is required to access information on whole NP sizes. EM provides average values on relatively small ensembles in contrast to the bulk values accessed by X-ray techniques. Besides the fact that the SAXS and WAXS techniques have different susceptibilities to size distributions, SAXS is easily affected by NP–NP interaction distances. Because of all the variables involved, there have yet to be proposed methodologies for cross-analyzing data from two techniques that can provide reliable quantitative results of dispersivity and crystallinity. In this work, a SAXS/WAXS-based methodology is proposed for simultaneously quantifying size distribution and degree of crystallinity of NPs. The most reliable easy-to-access size result for each technique is demonstrated by computer simulation. Strategies on how to compare these results and how to identify NP–NP interaction effects underneath the SAXS intensity curve are presented. Experimental results are shown for cubic-like CeO2 NPs. WAXS size results from two analytical procedures are compared, line-profile fitting of individual diffraction peaks in opposition to whole pattern fitting. The impact of shape dispersivity is also evaluated. Extension of the proposed methodology for cross-analyzing EM and WAXS data is possible. Full Article text
isp A study of stress, composition and grain interaction gradients in energy-dispersive X-ray stress analysis on materials with cubic symmetry By journals.iucr.org Published On :: 2024-06-07 The influence of various combinations of residual stress, composition and grain interaction gradients in polycrystalline materials with cubic symmetry on energy-dispersive X-ray stress analysis is theoretically investigated. For the evaluation of the simulated sin2ψ distributions, two different strategies are compared with regard to their suitability for separating the individual gradients. It is shown that the separation of depth gradients of the strain-free lattice parameter a0(z) from residual stress gradients σ(z) is only possible if the data analysis is carried out in section planes parallel to the surface. The impact of a surface layer z* that is characterized by a direction-dependent grain interaction model in contrast to the volume of the material is quantified by comparing a ferritic and an austenitic steel, which feature different elastic anisotropy. It is shown to be of minor influence on the resulting residual stress depth profiles if the data evaluation is restricted to reflections hkl with orientation factors Γhkl close to the model-independent orientation Γ*. Finally, a method is proposed that allows the thickness of the anisotropic surface layer z* to be estimated on the basis of an optimization procedure. Full Article text
isp Energy-dispersive Laue diffraction analysis of the influence of statherin and histatin on the crystallographic texture during human dental enamel demineralization By journals.iucr.org Published On :: 2024-09-25 Energy-dispersive Laue diffraction (EDLD) is a powerful method to obtain position-resolved texture information in inhomogeneous biological samples without the need for sample rotation. This study employs EDLD texture scanning to investigate the impact of two salivary peptides, statherin (STN) and histatin-1 (HTN) 21 N-terminal peptides (STN21 and HTN21), on the crystallographic structure of dental enamel. These proteins are known to play crucial roles in dental caries progression. Three healthy incisors were randomly assigned to three groups: artificially demineralized, demineralized after HTN21 peptide pre-treatment and demineralized after STN21 peptide pre-treatment. To understand the micro-scale structure of the enamel, each specimen was scanned from the enamel surface to a depth of 250 µm using microbeam EDLD. Via the use of a white beam and a pixelated detector, where each pixel functions as a spectrometer, pole figures were obtained in a single exposure at each measurement point. The results revealed distinct orientations of hydroxyapatite crystallites and notable texture variation in the peptide-treated demineralized samples compared with the demineralized control. Specifically, the peptide-treated demineralized samples exhibited up to three orientation populations, in contrast to the demineralized control which displayed only a single orientation population. The texture index of the demineralized control (2.00 ± 0.21) was found to be lower than that of either the STN21 (2.32 ± 0.20) or the HTN21 (2.90 ± 0.46) treated samples. Hence, texture scanning with EDLD gives new insights into dental enamel crystallite orientation and links the present understanding of enamel demineralization to the underlying crystalline texture. For the first time, the feasibility of EDLD texture measurements for quantitative texture evaluation in demineralized dental enamel samples is demonstrated. Full Article text
isp Measurable structure factors of dense dispersions containing polydisperse optically inhomogeneous particles By journals.iucr.org Published On :: 2024-09-25 Here, it is investigated how optical properties of single scatterers in interacting multi-particle systems influence measurable structure factors. Both particles with linear gradients of their scattering length density and core–shell structures evoke characteristic deviations between the weighted sum 〈S(Q)〉 of partial structure factors in a multi-component system and experimentally accessible measurable structure factors SM(Q). While 〈S(Q)〉 contains only the structural information of self-organizing systems, SM(Q) is additionally influenced by the optical properties of their constituents, resulting in features such as changing amplitudes, additional peaks in the low-wavevector region or splitting of higher-order maxima, which are not related to structural reasons. It is shown that these effects can be systematically categorized according to the qualitative behaviour of the form factor in the Guinier region, which enables assessing the suitability of experimentally obtained structure factors to genuinely represent the microstructure of complex systems free from any particular model assumption. Hence, a careful data analysis regarding size distribution and optical properties of single scatterers is mandatory to avoid a misinterpretation of measurable structure factors. Full Article text
isp Satispay raises EUR 60 million to further drive its service expansion By thepaypers.com Published On :: Mon, 11 Nov 2024 14:27:00 +0100 Italy-based unicorn Satispay has announced... Full Article
isp He Inherited A Devastating Disease. A CRISPR Gene-Editing Breakthrough Stopped It By www.scpr.org Published On :: Sat, 26 Jun 2021 10:20:08 -0700 Patrick Doherty volunteered for a new medical intervention of gene-editor infusions for the treatment of genetically-based diseases.; Credit: /Patrick Doherty Rob Stein | NPRPatrick Doherty had always been very active. He trekked the Himalayas and hiked trails in Spain. But about a year and a half ago, he noticed pins and needles in his fingers and toes. His feet got cold. And then he started getting out of breath any time he walked his dog up the hills of County Donegal in Ireland where he lives. "I noticed on some of the larger hill climbs I was getting a bit breathless," says Doherty, 65. "So I realized something was wrong." Doherty found out he had a rare, but devastating inherited disease — known as transthyretin amyloidosis — that had killed his father. A misshapen protein was building up in his body, destroying important tissues, such as nerves in his hands and feet and his heart. Doherty had watched others get crippled and die difficult deaths from amyloidosis. "It's terrible prognosis," Doherty says. "This is a condition that deteriorates very rapidly. It's just dreadful." So Doherty was thrilled when he found out that doctors were testing a new way to try to treat amyloidosis. The approach used a revolutionary gene-editing technique called CRISPR, which allows scientists to make very precise changes in DNA. "I thought: Fantastic. I jumped at the opportunity," Doherty says. On Saturday, researchers reported the first data indicating that the experimental treatment worked, causing levels of the destructive protein to plummet in Doherty's body and the bodies of five other patients treated with the approach. "I feel fantastic," Doherty says. "It's just phenomenal." The advance is being hailed not just for amyloidosis patients but also as a proof-of-concept that CRISPR could be used to treat many other, much more common diseases. It's a new way of using the innovative technology. "This is a major milestone for patients," says Jennifer Doudna of the University of California, Berkeley, who shared a Nobel Prize for her work helping develop CRISPR. "While these are early data, they show us that we can overcome one of the biggest challenges with applying CRISPR clinically so far, which is being able to deliver it systemically and get it to the right place," Doudna says. CRISPR has already been shown to help patients suffering from the devastating blood disorders sickle cell disease and beta thalassemia. And doctors are trying to use it to treat cancer and to restore vision to people blinded by a rare genetic disorder. But those experiments involve taking cells out of the body, editing them in the lab, and infusing them back in or injecting CRISPR directly into cells that need fixing. The study Doherty volunteered for is the first in which doctors are simply infusing the gene-editor directly into patients and letting it find its own way to the right gene in the right cells. In this case, it's cells in the liver making the destructive protein. "This is the first example in which CRISPR-Cas9 is injected directly into the bloodstream — in other words systemic administration — where we use it as a way to reach a tissue that's far away from the site of injection and very specifically use it to edit disease-causing genes," says John Leonard, the CEO of Intellia Therapeutics, which is sponsoring the study. Doctors infused billions of microscopic structures known as nanoparticles carrying genetic instructions for the CRISPR gene-editor into four patients in London and two in New Zealand. The nanoparticles were absorbed by their livers, where they unleashed armies of CRISPR gene-editors. The CRISPR editor honed in on the target gene in the liver and sliced it, disabling production of the destructive protein. Within weeks, the levels of protein causing the disease plummeted. Researchers reported at the Peripheral Nerve Society Annual Meeting and in a paper published in The New England Journal of Medicine. "It really is exciting," says Dr. Julian Gillmore, who is leading the study at the University College London, Royal Free Hospital. "This has the potential to completely revolutionize the outcome for these patients who have lived with this disease in their family for many generations. It's decimated some families that I've been looking after. So this is amazing," Gillmore says. The patients will have to be followed longer, and more patients will have to be treated, to make sure the treatment's safe, and determine how much it's helping, Gillmore stresses. But the approach could help those struck by amyloidosis that isn't inherited, which is a far more common version of the disease, he says. Moreover, the promising results potentially open the door for using the same approach to treatment of many other, more common diseases for which taking cells out of the body or directly injecting CRISPR isn't realistic, including heart disease, muscular dystrophy and brain diseases such as Alzheimer's. "This is really opening a new era as we think about gene-editing where we can begin to think about accessing all kinds of different tissue in the body via systemic administration," Leonard says. Other scientists who are not involved in the research agree. "This is a wonderful day for the future of gene-editing as a medicine," agree Fyodor Urnov, a professor of genetics at the University of California, Berkeley. "We as a species are watching this remarkable new show called: our gene-edited future." Doherty says he started feeling better within weeks of the treatment and has continued to improve in the weeks since then. "I definitely feel better," he told NPR. "I'm speaking to you from upstairs in our house. I climbed stairs to get up here. I would have been feeling breathless. I'm thrilled." Copyright 2021 NPR. To see more, visit https://www.npr.org. This content is from Southern California Public Radio. View the original story at SCPR.org. Full Article
isp Reuse of Disposable Medical Masks During Flu Pandemic Not Recommended - Reusing Respirators Is Complicated By Published On :: Thu, 27 Apr 2006 05:00:00 GMT Use of protective face coverings will be one of many strategies used to slow or prevent transmission of the flu virus in the event of a pandemic, even though scientific evidence about the effectiveness of inexpensive, disposable medical masks and respirators against influenza is limited. Full Article
isp Independent Reviews, Environmental Assessments Needed to Build Trust and Inform DOE NNSA’s Plans if it Proceeds with the Dilution and Disposal Process of Surplus Plutonium By Published On :: Fri, 30 Nov 2018 06:00:00 GMT If the dilute and dispose approach for disposing of the surplus plutonium in the Waste Isolation Pilot Plant (WIPP) is fully implemented, the U.S. Department of Energy (DOE) should use two independent review teams to develop public trust in and improve its decisions, says a new interim report by the National Academies of Sciences, Engineering, and Medicine. Full Article
isp Dispersants Can Be an Effective Tool for Managing Impacts During a Major Marine Oil Spill, Report Concludes By Published On :: Fri, 05 Apr 2019 05:00:00 GMT A new report from the National Academies of Sciences, Engineering, and Medicine examines the effects and efficacy of using dispersants in marine oil spill response. Full Article
isp New Report Calls for a National System to Measure Equity in Education, Identify Disparities in Outcomes and Opportunity By Published On :: Thu, 13 Jun 2019 05:00:00 GMT A centralized, consistently reported system of indicators of educational equity is needed to bring attention to disparities in the U.S. education system, says a new report by the National Academies of Sciences, Engineering, and Medicine. Full Article
isp Addressing Patients’ Social Needs Within Health Care Delivery Is Key to Improving Health Outcomes and Reducing Health Disparities, New Report Says By Published On :: Wed, 25 Sep 2019 04:00:00 GMT Whether a patient has a safe place to live or healthy food to eat has an important influence on their health, but such nonmedical social needs have not traditionally been addressed in routine health care visits. Full Article