Oct 27, 2022

Kennedy’s statecraft in the missile crisis provides a rich source of clues that can help illuminate the challenge the United States now faces, and the choices President Joe Biden is making.

Dec 15, 2023

Calder Walton writes that if proved, Victor Manuel Rocha's espionage would place him among the longest-serving spies in modern times. Allowing him to operate as a spy in the senior echelons of the U.S. government for so long would represent a staggering U.S. security failure.

Allowing for moves that create quantum superpositions makes a quantum version of a Rubik’s cube incredibly complex, but not impossible to solve

Probability of operating an alarm clock

Highlights: India introduces the Aarogya Maitri Aid Cube, a portable hospital designed for swift deployment in

Tata Group has joined hands with General Electric Ventures, Microsoft Ventures and others to set up a new technology incubator in Israel.

Cuba Earthquake Updates: ആദ്യത്തെ ഭൂചലനത്തിന് ഒരു മണിക്കൂറിനു ശേഷമായിരുന്നു രണ്ടാമത്തെ ഭൂചലനം  ഉണ്ടായത്

Before embracing AI, it's essential for companies to have a solid foundation in their traditional technology infrastructure. 

Durham : Duke University Press, [2023]

Minneapolis : University of Minnesota Press, [1999]

Scientists at the Indian Institute of Millet Research are helping start-ups create products, from icecream to beer, with the grain at Nutrihub

The outdoor setting of Cubbon Reads and Cubbon Book Club fosters reading as well as social connections

[United States] : Kindle Direct Publishing, 2020.

Nyack, New York : African Diaspora Press, 2012.

Actor, writer and rap legend Ice Cube joins WIRED to answer his most searched questions from the internet. Who's his best friend? Is he from Compton or South Central L.A.? Will there ever be another Friday movie? Cube answers these questions and more in the WIRED Autocomplete Interview. SAG-AFTRA members are currently on strike; as part of the strike, union actors are not promoting their film and TV projects. This interview was conducted prior to the strike.

Business magnate, NBA owner, angel investor and self-made mogul Mark Cuban answers your questions from Twitter.

Actor Prakash Raj’s innovative incubator for theatre and arts offers a comprehensive production process, stipends for actors/techs, lodging, kitchen and tech support. It also plans to promote fine arts and film in the future.

Actor Prakash Raj says fans will soon get to see him perform live on stage

Renowned American photographer Jack Watson travelled to Cuba on a legal humanitarian visa. He chronicled his journey with breath-taking, and often heart breaking images of he Cuba people, cites, and countryside. Watson describes his visit:  “I had stepped back in time 50 years — this was my first impression of Cuba. My journey, which began […]

The clean tech start-up specialises in electrifying vehicle refrigeration systems for mid-mile and last-mile cold chain logistics

The new device comes with hands-free Alexa control and a new processor 

While DronaMaps is helping map Covid-19 patients in Haryana and other states, Blinkin has provided remote tech support for installing air ventilation systems in two Wuhan hospitals

Tata Group has joined hands with General Electric Ventures, Microsoft Ventures and others to set up a new technology incubator in Israel.

Singa, an African lion living in Pakawi Park Zoo in Belgium struggled to look after his five cubs who screamed every time he tried to move them while mum was recovering from an injury at the vet.

Singa, an African lion living in Pakawi Park Zoo in Belgium struggled to look after his five cubs who screamed every time he tried to move them while mum was recovering from an injury at the vet.

Videocon Mobiles has launched its latest 4G smartphone, Cube 3 (V50JL) in India. Priced at Rs 8,490, the smartphone will available across all retail stores.

Bicontinuous cubic structures in soft matter consist of two intertwining labyrinths separated by a partitioning layer. Combining experiments, numerical modelling and techniques in differential geometry, we investigate twinning defects in bicontinuous cubic structures. We first demonstrate that a twin boundary is most likely to occur at a plane that cuts the partitioning layer almost perpendicularly, so that the perturbation caused by twinning remains minimal. This principle can be used as a criterion to identify potential twin boundaries, as demonstrated through detailed investigations of mesoporous silica crystals characterized by diamond and gyroid surfaces. We then discuss that a twin boundary can result from a stacking fault in the arrangement of inter-lamellar attachments at an early stage of structure formation. It is further shown that enhanced curvature fluctuations near the twin boundary would cost energy because of geometrical frustration, which would be eased by a crystal distortion that is experimentally observed.

Serial crystallography is having an increasing impact on structural biology. This emerging technique opens up new possibilities for studying protein structures at room temperature and investigating structural dynamics using time-resolved X-ray diffraction. A limitation of the method is the intrinsic need for large quantities of well ordered micrometre-sized crystals. Here, a method is presented to screen for conditions that produce microcrystals of membrane proteins in the lipidic cubic phase using a well-based crystallization approach. A key advantage over earlier approaches is that the progress of crystal formation can be easily monitored without interrupting the crystallization process. In addition, the protocol can be scaled up to efficiently produce large quantities of crystals for serial crystallography experiments. Using the well-based crystallization methodology, novel conditions for the growth of showers of microcrystals of three different membrane proteins have been developed. Diffraction data are also presented from the first user serial crystallography experiment performed at MAX IV Laboratory.

Digitonin has long been used as a mild detergent for extracting proteins from membranes for structure and function studies. As supplied commercially, digitonin is inhomogeneous and requires lengthy pre-treatment for reliable downstream use. Glyco-diosgenin (GDN) is a recently introduced synthetic surfactant with features that mimic digitonin. It is available in homogeneously pure form. GDN is proving to be a useful detergent, particularly in the area of single-particle cryo-electron microscopic studies of membrane integral proteins. With a view to using it as a detergent for crystallization trials by the in meso or lipid cubic phase method, it was important to establish the carrying capacity of the cubic mesophase for GDN. This was quantified in the current study using small-angle X-ray scattering for mesophase identification and phase microstructure characterization as a function of temperature and GDN concentration. The data show that the lipid cubic phase formed by hydrated monoolein tolerates GDN to concentrations orders of magnitude in excess of those used for membrane protein studies. Thus, having GDN in a typical membrane protein preparation should not deter use of the in meso method for crystallogenesis.

Several oils were examined for use in the cleaning and cryoprotection of crystals in the lipidic cubic phase in terms of their effect on the crystal stability, the background scattering and the facilitation of the experiment.

Staff had been on a pregnancy watch focused on the 3 1/2-year-old clouded leopard Jao Chu (JOW-chew) for four days. Jao Chu gave birth to the first cub at 6:04 p.m. and the second cub at 6:20 p.m.

The post Clouded leopard cubs born at National Zoo’s Front Royal campus on Valentine’s Day appeared first on Smithsonian Insider.