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Director-General of UNESCO to be Presented with Papers of Pioneering Insulin Researchers at University of Toronto

TORONTO, ON — Media are invited to take photos on Tuesday, November 18, of Irina Bokova, Director-General of UNESCO, as Christina Cameron, President of the Canadian Commission for UNESCO, presents to her the University of Toronto’s Thomas Fisher Rare Book Library’s Discovery of Insulin Collections. Last year the Library’s collections—only one of four in Canada […]




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Researchers identify security and privacy issues in Baidu Browser

Toronto, ON — A new report from the University of Toronto’s Citizen Lab reveals that Baidu Browser, a popular mobile browser based in China and used by millions of people, has many privacy and security issues that could put users’ communications at risk. Baidu Browser is available in both an Android and Windows version, and […]




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Researchers identify major security and privacy issues in Popular China Browser Application, QQ

Toronto, ON — A new study from the University of Toronto’s Citizen Lab identifies security and privacy issues in QQ Browser, a mobile browser produced by China-based Internet giant Tencent, which may put many millions of users of the application at risk of serious compromise. Citizen Lab researchers identified problems in both the Android and […]




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Researchers Uncover Extensive Twitter-based Cyber Espionage Campaign Targeting UAE Dissidents, Journalists

Toronto, ON – A new report from the University of Toronto’s Citizen Lab reveals a sophisticated international cyber-espionage campaign targeting journalists and activists whose work concerns the United Arab Emirates. The campaign used elaborate ruses, including fake organizations and journalists, to engage targets online, then entice them to open malicious files and links containing malware capable […]




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Researchers Uncover New Cyber-Espionage Operation Targeting the Syrian Opposition

Toronto, ON – A new report from the Citizen Lab at the Munk School of Global Affairs at the University of Toronto reveals a new cyber-espionage operation targeting the Syrian opposition.  The operation used clever deceptions to trick targets into opening malicious files and links containing malware capable of monitoring computers and Android phones. The operation, […]




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Researchers Expose Censorship on Popular Chat App, WeChat

Toronto, ON – Researchers at the University of Toronto’s Citizen Lab are publishing a report today that reveals how WeChat (the most popular chat app in China) censors content. The results show WeChat has separate censorship policies for users in China and internationally, with the majority of censorship targeted for China accounts, and has removed […]




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NSERC prizes awarded to five University of Toronto scholars - Backing research into billion-year-old water, evolution of plants, faster disease diagnosis, microbial energy

Backing research into billion-year-old water, evolution of plants, faster disease diagnosis, microbial energy Toronto, ON — Five University of Toronto scholars have been awarded prizes in 2016 by the Natural Sciences and Engineering Research Council of Canada (NSERC) – the largest tally of winners at any university in Canada. “Our exceptional performance in the NSERC awards […]




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University of Toronto researcher first to open lab notes in real time

Toronto, ON — University of Toronto researcher Rachel Harding will be the first known biomedical researcher to welcome the world to review her lab notes in real time. The post-doctoral fellow with U of T’s Structural Genomics Consortium (SGC) is also explaining her findings to the general public through her blog. She hopes her open […]



  • Health & Medicine
  • Media Releases
  • New Media & Technology
  • University of Toronto

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U of T opens one of first mental health and physical activity research centres

Toronto, ON — The University of Toronto’s Faculty of Kinesiology and Physical Education has launched the Mental Health and Physical Activity Research Centre (MPARC) — one of the first research facilities to integrate the study of physical activity and mental health in Canada and internationally. Opened on February 25, this multidisciplinary centre will address the […]



  • Health & Medicine
  • Kinesiology and Physical Education
  • Media Releases
  • University of Toronto

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University of Toronto Researcher Wins €1M Brain Prize – the “Nobel of Neuroscience”

Toronto, ON — Professor Graham Collingridge has been awarded the world’s most valuable prize for brain research. Prof. Collingridge, Chair of the Department of Physiology, was one of three recipients of the Brain Prize, awarded by the Grete Lundbeck European Brain Research Foundation in Denmark, for his research into the mechanisms of memory. The Brain […]




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$27-million investment to fast-track stem cell research at U of T

Toronto, ON – Discovering stem cells here was just the beginning. Now, the University of Toronto is pushing the frontiers of regenerative medicine even further with a $27-million investment in 20 transformative projects. The team projects, which range from attempting to improve failing eyesight in aging populations to finding better treatments for stroke and liver disease, […]




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Research Reveals How Much Sugar is in Prepackaged Foods in Canada

Toronto, ON – Researchers at the University of Toronto have investigated the amount of free sugar in Canadian prepackaged foods and beverages. The results suggest that new guidelines and better food labeling is needed to help consumers make better choices. Free sugar, commonly referred to as added sugar, is considered a “hidden” source of calories, as […]




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U of T Cities Podcast Ep. 2 The Future of Transit - Research and startups pushing transit beyond the simple subway-or-streetcar divide

Research and startups pushing transit beyond the simple subway-or-streetcar divideThis edition of U of T Cities features researchers and entrepreneurs working to build the future of transit. Reimagine the downtown and beyond with transit policy expert Prof. Eric Miller; Richard Sommer, dean of the Daniels Faculty of Architecture, Landscape and Design; and alumnus Taylor Scollon, […]




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Fujitsu Laboratories and University of Toronto Enter Strategic Partnership - Fujitsu Laboratories establishes new research center in Toronto to accelerate Quantum-Inspired Computing

Fujitsu Laboratories establishes new research center in Toronto to accelerate Quantum-Inspired ComputingToronto, ON – Kawasaki, Japan and Toronto, Canada, September 20, 2017 Fujitsu Laboratories Ltd. and the University of Toronto have entered into a new partnership, with Fujitsu Laboratories establishing a new research center in Toronto focused on bolstering R&D into breakthrough quantum computing technologies. In […]




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New research Chair for investor rights—the first of its kind—to investigate better protections for Canadians

Toronto, ON — Professor Anita Anand, a corporate law and governance expert, is the new J. R. Kimber Chair in Investor Protection and Corporate Governance at the University of Toronto Faculty of Law—the first research chair for investor rights in North America—thanks to a generous gift from well-known philanthropist, the Hon. Hal Jackman, LLB 1956, […]




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The Moth Radio Hour: Sailing on an Alien Sea

In this hour we explore stories relating to STEM (Science/Technology/Engineering and MATH): we travel from the laboratories of the Antarctic to the icy seas of Saturn’s moon Titan - we learn that predisposition does not mean predestined and sometimes A is larger than C. This episode is hosted by Jay Allison of Atlantic Public Media, the producer of this show.

Hosted by: Jay Allison

Storytellers:

James McClintock a scientist researching at McMurdo Station, Antartica makes an interesting discovery.

Lone Frank deep dives into personal genomics

Dhaya Lakshminarayanan gets entangled in the language of math.

Ellen Stofan sets her sights on exploring an alien sea.




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25 Years of Stories: Searching for Direction

On this episode, we get in the holiday spirit with a tale about a very special Xmas. Then, we discuss how directors can shape Moth stories. This episode is hosted by Kate Tellers.

Storyteller:

Peter Aguero




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In Search of Freedom: Juan Rodriguez

We take a look at the meaning of Independence Day through story. This episode is hosted by Larry Rosen.

Storyteller:

Juan Rodriguez recounts his American journey.




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The Moth Radio Hour: The Hot Seat

Aerial antics, magic tricks, and unwelcome rescue missions. In this hour, stories of momentous decisions, massive undertakings, and opportunities with no second chances. This episode is hosted by Catherine Burns. The Moth Radio Hour is produced by The Moth and Jay Allison of Atlantic Public Media.

Storytellers:

In an attempt to be Maverick (from Top Gun), Will Mackin goes to Navy Flight School.

Siegfried Tieber gets hooked on magic.

Samantha Mathis goes on a mission to bring her father home.




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The Moth Radio Hour: Signed, Sealed, Delivered - Stories about Letters

Special delivery!—a Moth Radio Hour all about letters. At work, for romance, and to the Tooth Fairy. This episode is hosted by Moth Executive Producer, Sarah Austin Jenness. The Moth Radio Hour is produced by The Moth and Jay Allison of Atlantic Public Media.

Storytellers:

Meg Ferrill's letter is read aloud in her human sexuality class.

Danielle Dardashti is surprised by the severance letter she receives.

Matty Struski pens a letter in an attempt to win back his ex.

Lu Levin strikes up a correspondence with the Tooth Fairy.

Otis Gray gets a job writing rejection letters.

Stacey Perlman visits a medium, who knows of a letter to the great beyond.




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The Future of ADHD Research: Promising Frontiers

In the second of this two-part series, an expert predicts the innovations that could reshape how ADHD is diagnosed and treated in the years to come.



  • ADDitude for Professionals
  • ADHD Medication & Treatment
  • ADHD Medications
  • ADHD News & Research
  • ADHD Therapies
  • Natural Approaches to Managing ADHD
  • ADHD Research and News
  • Winter 2024 Issue of ADDitude Magazine

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UL Chemical Safety Research and Georgia Institute of Technology Release Pioneering 3D Printing Research

Desktop 3D printers generate ultrafine particles (UFPs) while in operation. UFPs may pose a health concern since they are the size of nanoparticles and may be inhaled and penetrate deep into the human pulmonary system.




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Is Your Sealed Device Leak Testing Method All Wet?

From e-vehicles to consumer electronics and implantable medical devices, standards and expectations for the quality and reliability of sealed devices and components continue to rise. This puts the burden on manufacturers to employ methods of leak testing that are objective, reliable and repeatable.




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Westmoreland Mechanical Testing and Research Becomes a Member of America Makes

Through its memberships in America Makes, WMT&R joins other leading member organizations from industry, academia, government, non-government agencies, and workforce and economic development resources that are working together to innovate and accelerate additive manufacturing and 3-D printing.




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At Odds with the Sea

At Odds with the Sea by Lisa Keene is a(n) Limited Edition. The Edition is Limited to 95 pcs




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Songs Of The Seas

Songs Of The Seas by Dan Medina is a(n) Limited Edition. The Edition is Limited to Limited Edition of 150 pcs




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Songs Of The Seas AP

Songs Of The Seas AP by Dan Medina is a(n) Limited Edition. The Edition is Limited to Artist Proof of 15 pcs




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12th annual Norman Bethune Symposium showcases breadth of ongoing research

12th annual Norman Bethune Symposium showcases breadth of ongoing research


Tuesday, June 25, 2024 Guest Author

Our partnership with the Centre for Blood Research (CBR) at the University of British Columbia (UBC) is helping to train the next generation of researchers in transfusion science. This blog post highlights just some of the achievements in education, training or knowledge mobilization accomplished by CBR trainees.  

This is an abbreviated repost that originally appeared on the Centre for Blood Research blog in June 2024. It was written by trainees Joyce Teodoro (PhD student in the lab of Canadian Blood Services’ adjunct scientist Dr. Hongshen Ma) and Kiran Toor (Masters student at CBR in the lab of Dr. Brown), with edits provided by Kaitlyn Chuong (communications and programs coordinator at CBR).  

On April 18th, 2024, the Centre for Blood Research (CBR) held their 12th annual Norman Bethune Symposium, a renowned research event that gathers scientists, clinicians, healthcare professionals, and trainees to discuss advancements in the field of blood research. The symposium was held at UBC Robson Square, on the traditional territory of the Musqueam, Squamish and Tsleil-Waututh people. 

The full day event consisted of expert talks on thalassemia, thrombocytopenia, sickle cell disease, and other bleeding disorders. Research trainees delivered impressive presentations on innovative topics including engineering cells for cancer immunotherapy and computational approaches to inhibit Klebsiella pneumoniae. The event showcased nearly 30 trainee research posters, demonstrating the breadth of ongoing research. 

CBR Director, Dr. Ed Conway, began with the opening remarks, followed by the presentation by Dr. Christian Kastrup, Professor at the Medical College of Wisconsin and Senior Investigator at Versiti Blood Research Institute. Dr. Kastrup’s presentation focused on his work on genetically modifying transfusable donor platelets using mRNA-lipid nanoparticles. Following this, there were a series of presentations on the topic of bleeding disorders. It was a research-filled day that honored the contributions of Drs. Don Brooks and Dana Devine. 

Blood research & reflections 

The symposium was an amazing opportunity to learn about the exciting advances in blood research. It also served as a great platform for speakers to share their personal experiences with blood disorders, as well as for scientists to discuss their professional path in blood sciences. 

Attendees were fortunate to hear Ritika Rakshit share her personal journey with thalassemia, a genetic blood disorder characterized by the body’s inability to produce enough hemoglobin. She detailed her experience from being diagnosed to her treatment plans including being on extramedullary hematopoiesis (EMH) and switching to luspatercept. She offered insights into her hesitancy to switch medications and highlighted the invaluable support of her clinical team. Ritika continues to be an advocate for thalassemia in her role on the patient advocacy board. It was an eye-opening opportunity to be able to hear from a patient reflect on their own journey and understand their perspective on living with a blood disorder. 

Dr. Geraldine Walsh, a development scientist with Canadian Blood Services, also gave an insightful talk describing her career path in blood sciences. Drawing from her experiences, she shared several pieces of advice on navigating a career in science. She highlighted the importance of finding work that we are passionate about, building strong relationships, and learning from those around us. Dr. Walsh concluded her talk by encouraging attendees, especially research trainees, to explore various career opportunities, including those that may deviate from the conventional scientific career trajectory. 

Celebrating Drs. Don Brooks and Dana Devine 

One of the highlights of the symposium was the talk by Dr. Cedric Carter, which celebrated Drs. Don Brooks and Dana Devine’s achievements and contributions. Drs. Don Brooks and Dana Devine are two of the founding members of the Centre for Blood Research (CBR). In addition to their significant and impactful contributions to the field of transfusion science and medicine, they have been instrumental in promoting research and developing initiatives through various leadership roles. Dr. Brooks has served as Associate Vice-President, Research at UBC and Founding Director of UBC’s Support Programs to Advance Research Capacity (SPARC). He has also served as a member of the Board of Directors for TRIUMF, Provincial Health Services Authority, and BC Emergency Health Services. Dr. Devine has held numerous leadership positions, which include her role as chief scientist at Canadian Blood Services, director of the CBR, president of the Association for the Advancement of Blood and Biotherapies (AABB), and editor-in-chief of Vox Sanguinis, a transfusion medicine journal. Their dedication and commitment to scientific discovery through research and development serve as inspiration for future generations of scientists. 

Inaugural Don Brooks and Dana Devine Transfusion Science Innovation Address 

In honour of Drs. Don Brooks and Dana Devine’s scientific contributions to advancing transfusion science and medicine, the inaugural Don Brooks and Dana Devine Transfusion Science Innovation Address was presented by Dr. Stephen Withers. Dr. Withers, in collaboration with Dr. Jay Kizhakkedathu’s lab, worked on identifying efficient enzymes for cleaving terminal sugar structures on the surface of red blood cells (RBCs), which are responsible for determining blood types. By removing these terminal sugar structures, A and B type RBCs can be converted to the universal donor blood type O, which can increase blood supply for transfusion applications. By screening the human gut microbiome for enzymes that can cleave these terminal sugar structures, they identified a pair of enzymes (FpGalNAc deacetylase and FpGalactosaminidase) that can convert type A to type O blood.  

Posters & awards 

This year, there were 29 posters presented by various graduate trainees, postdoctoral fellows, clinical fellows and research associates! These included members within the CBR, but we also had the pleasure of having presenters come from out of town. Multiple trainees from the University of Alberta, University of Toronto & Queen’s University were able to attend the symposium with the support of the CBR Travel Award.  

The Best Poster Presentation went to Dr. Georgina Butler from the Overall Lab for their poster on “SARS-CoV-2 main protease 3CLpro (nsp5), regulates the formation of tunnelling nanotubes by coordinating cytoskeleton reorganization.”  

Our final speaker was Dr. Ed Pryzdial with an exciting talk on Dengue virus-induced thrombocytopenia. Afterwards, a reception was held and attendees got to network and socialize with each other to celebrate the end of another incredible symposium! 

A huge thank you to everyone who attended, to our speakers and all presenters! 

The Centre for Blood Research would like to thank their event sponsors, without whom the 12th Annual Norman Bethune Symposium would not have been possible: the Naiman-Vickars Endowment Fund, Canadian Blood Services, Novo Nordisk, GRIFOLS, CSL Behring, ALEXION, Sobi and Pfizer.  


Canadian Blood Services – Driving world-class innovation 

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.  

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. 

Related blog posts


Tuesday, August 22, 2023
John Perrier

The Centre for Blood Research (CBR) at the University of British Columbia celebrated its 20-year anniversary on July 7th by inviting CBR alumni to join current members in learning about the beginnings of the centre. Read about the celebration and the history of the centre in this blog reposted from CBR.


Thursday, June 02, 2022
Canadian Blood Services trainees

The 11th annual Centre for Blood Research Norman Bethune Symposium was held on April 6, 2022. With a focus on recent research advances in bleeding and thrombosis, the symposium engages scientists and clinicians at all levels of training.


Wednesday, January 24, 2024
Dr. Travis Sztainert

Read about the new Canadian Blood Services Dana Devine Award program. This blog post, written by the Centre for Blood Research (CBR) includes reflections from individuals who worked with Dr. Devine.




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Driving excellence: The Centre for Blood Research and Canadian Blood Services renew collaboration to advance blood science education and training

Driving excellence: The Centre for Blood Research and Canadian Blood Services renew collaboration to advance blood science education and training


Tuesday, July 30, 2024 Kaitlyn Chuong

This blog was originally prepared by CBR communications and programs coordinator Kaitlyn Chuong and former Canadian Blood Services knowledge broker Dr. Travis Sztainert, with edits provided by Abby Wolfe. 

After more than 20 years, the Centre for Blood Research (CBR) and Canadian Blood Services are proud to share that they have renewed their collaboration agreement which supports education, training and knowledge mobilization for the next generation of trainees and researchers in blood science and transfusion at CBR.  

The collaboration agreement which is administered by Innovation and Portfolio Management at Canadian Blood Services has recently been extended for three more years to 2027. This agreement formalizes the next iteration of this long-standing partnership and is the result of continued commitment from both organizations to improve blood research.  

This partnership emerged in response to recommendations made following Canada’s public inquiry into the contaminated blood crisis of the 1980s and 1990s. Thus, to address a recognized gap in transfusion science knowledge, in 2002, a group of visionary blood researchers at the University of British Columbia (UBC) established Canada’s first interdisciplinary blood research centre — an entirely unique and valuable resource for established and emerging blood scientists. With its creation, the CBR brought together a wide range of multi-talented investigators to develop highly specialized labs to study blood and transfusion science. Since its inception, the CBR has grown to include more than 35 basic science, applied science, social science and clinical investigators in 12 departments, representing 6 faculties at UBC, with a focus on advancing knowledge of transfusion science and medicine in the lab and in the clinic.  

"We are delighted to extend our partnership with the Centre for Blood Research through 2027. This renewal highlights our shared commitment to advancing education, training, and research in transfusion science. Together, we aim to drive innovation and improve transfusion practices, ensuring a safer and more effective future for the Canadian blood system." 

Dr. Chantale Pambrun
Senior Medical Director, Innovation & Portfolio Management 

“The long-term relationship of Canadian Blood Services and the CBR has been nothing less than fantastic! By combining resources and sharing knowledge, education and research outputs, this unique partnership has resulted in more rapid and meaningful advances that are recognized locally, nationally and internationally. The entire transfusion medicine community has benefitted and will continue to do so.”  

Dr. Ed Conway
Director of the Centre for Blood Research

The partnership of Canadian Blood Services was integral to creating the Centre for Blood Research, providing essential start-up funding and continuing to support infrastructure for the centre and its training and education programs. Several Canadian Blood Services scientists are active members within the Centre for Blood Research including senior scientist Dr. Ed Pryzdial and adjunct scientists Dr. Ed Conway, Dr. Hongshen Ma and Dr. Jay Kizhakkedathu

Learn more about some of the research these scientists and members of their labs undertake in our previous R.E.D. blogs and videos:  

The CBR is grateful for Canadian Blood Services’ continuous support, without which its many educational, training and research programs would not be possible. This includes, for example, CBR’s Graduate Award Program and Summer Studentship Program, as well as the CBR's weekly seminar series and the annual Earl W. Davie and Norman Bethune symposia. 


Canadian Blood Services – Driving world-class innovation  

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. 

Related blog posts


Tuesday, June 25, 2024
Guest Author

The Centre for Blood Research (CBR) Norman Bethune Symposium gathers scientists, clinicians, healthcare professionals, and trainees to discuss advancements in the field of blood research. The 12th Annual event, held in April 2024, consisted of expert talks on thalassemia, thrombocytopenia, sickle cell disease, and other bleeding disorders, demonstrating the breadth of ongoing research.


Tuesday, May 14, 2024
Abby Wolfe

The 2024 Canadian Blood Services’ Lay Science Writing Competition is open for submissions from research trainees in Canadian Blood Services’ research network until Friday, June 14, 2024. The theme this year is: “Connecting science with society”. Additional competition details available in this post!


Wednesday, February 21, 2024
Dr. Travis Sztainert

In this blog post, read about the 2023 Earl W. Davie Symposium held at the Centre for Blood Research (CBR) - a research event that brings together scientists, medical doctors, healthcare professionals, and trainees in the field of blood research and beyond.




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Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils

Canadian Blood Services discovery research lab contributes to new knowledge on neutrophils


Thursday, August 29, 2024 Abby Wolfe

Dr. Donald R. Branch’s work as a discovery scientist at Canadian Blood Services focuses on immunotherapy, seeking to further enhance understanding of the cellular and molecular mechanisms involved in autoimmune diseases. Based in Toronto, Dr. Branch’s laboratory develops models of rheumatoid arthritis, Alzheimer’s disease, immune thrombocytopenia (ITP) and multiple sclerosis in mice. These models are particularly useful in examining how cells affected by these conditions respond to current therapeutic agents like intravenous immunoglobulin – a blood product made from human plasma commonly known as IVIg – and investigating potential alternative therapeutics.  

Over the years, Dr. Branch’s lab research findings have included the discovery of a special reagent that makes identification of antibodies easier by “zapping" autoantibodies,answers around unexpected side effects of IVIg therapy, and insights around recipients’ responses to bone marrow transplantation. It has also earned him numerous awards and accolades, including four from AABB, the Association for the Advancement of Blood & Biotherapies.

Dr. Don Branch, Canadian Blood Services senior scientist

New knowledge about neutrophils

Recently, contributions from Dr. Branch’s lab helped a U.K.-based team of researchers discover new information about how neutrophil function and activity is regulated. Neutrophils are a type of white blood cell that are part of the body’s normal immune response. A person’s neutrophil levels may be affected by infections as well as chronic or acute illnesses. Patients who have very low neutrophil counts and/or persistent infections may receive a boost to their neutrophil levels via granulocyte transfusion therapy. However, in some diseases, overactivation of neutrophils can also create an inflammatory environment and harm healthy tissue.

The research has been published in the high-impact scientific journal, Nature. This publication has filled a gap in knowledge about the mechanisms involved in maintaining balance between neutrophils’ infection-fighting power and inflammation-causing potential. As Dr. Branch describes: “This research by Dr. Brown and team shows that the myeloid inhibitory C-type lectin enzyme, which is known as MICL, controls neutrophil activity in rheumatoid arthritis. It is likely that MICL also regulates neutrophil activity in general. This suggests that if therapeutics can be designed to target MICL, they may be useful in controlling inflammation and infection. It is a fundamental finding that will change our understanding of the biology of neutrophils.”  

Discovery research, like the study to which Don and Ruqayyah contributed, is essential to improving patient care in the long run. New biomedical insights are essential to crafting new drugs and new therapeutic approaches in a rational way.

Dr. William (Bill) Sheffield, Canadian Blood Services senior scientist and associate director of research

Discovery research expertise leads to new collaboration  

The special mouse model that Dr. Branch’s lab uses is known as K/BxN. In this model, two mouse populations are selectively bred to produce offspring whose genetic material carry an antibody that destroys bone cartilage. An arthritis-causing serum containing this destructive antibody can then be obtained from the mice for use as a reagent in research. This process is termed “serum-transfer arthritis” and has been used by many investigators in the study of treatments that may alleviate the condition. 

Knowledge of Dr. Branch’s lab’s expertise in this area prompted a connection to the team of researchers at the Universities of Exeter and Aberdeen in the U.K. for this study. Says Dr. Branch, “In 2021, I supported a successful application to Canadian Blood Services’ Blood Efficiency Accelerator Program (BEAP) by Dr. Maria Fernandes, a researcher from  Héma-Québec who works with neutrophils. Through this collaboration, Dr. Fernandes was aware that I work on rheumatoid arthritis with K/BxN mice, and she also knew that Dr. Gordon Brown in the U.K. was looking to collaborate with a researcher in this area for some planned neutrophil research. My lab, which included postdoctoral fellow Dr. Ruqayyah Almizraq at the time, contributed to Dr. Brown’s research by providing the sera from our K/BxN mice. With this sera, Dr. Brown and his collaborators were able to induce rheumatoid arthritis and show that it could be resolved by removing the inhibition of a specific enzyme.”  

Science that is never boring

The Branch lab is currently using these same mouse models to investigate whether a recombinant protein called IgG1 Fc hexamer could be an effective replacement for IVIg in the treatment of autoimmune conditions like rheumatoid arthritis and ITP. While early results are promising, continued work is needed. In fact, back in 2018, Dr. Branch was asked in a previous R.E.D. blog post to describe what he found to be the most exciting part of science. Reflecting on the same question now, he reiterates that his response still rings true after 50 years in the field:   

The most exciting part of science is that when you do good science, you get more questions than you get answers, which means it is never boring. There is no end to imagination; new ideas, theories, experiments and discoveries occur often and provide a level of excitement to which many other professions cannot attest.

Dr. Donald (Don) Branch, Canadian Blood Services senior scientist


Canadian Blood Services – Driving world-class innovation 

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. 

Related blog posts


Tuesday, March 28, 2023
Aldis Brennan

Dr. Donald Branch, Canadian Blood Services senior scientist, has received the Dale A. Smith Memorial Award for his discovery of the ZZAP reagent. This award, from the Association for the Advancement of Blood & Biotherapies (AABB), recognizes the application of technology to the practice of transfusion medicine or biotherapies.


Thursday, March 16, 2023
Beth Binnington, Senior Research Assistant

Students from the Undergraduate Pathology Alliance at Western University posed insightful questions to researchers during an interactive visit to the research laboratory of Dr. Donald Branch, Canadian Blood Services senior scientist in February 2023.


Wednesday, February 28, 2018
Dr. Kendra Hodgkinson

For this instalment of “Meet the researcher”, we met with Dr. Donald Branch, a scientist at Canadian Blood Services who studies infectious diseases and immunology. How long have you been with Canadian Blood Services? I started with the Canadian Red Cross at the Edmonton Blood Centre in December 1985...




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Celebrating young researchers: A look back at CBR Research Day 2024

Celebrating young researchers: A look back at CBR Research Day 2024


Tuesday, September 10, 2024 Trainees

Our partnership with the Centre for Blood Research (CBR) at the University of British Columbia (UBC) is helping to train the next generation of researchers in transfusion science. This blog post highlights just some of the achievements in education, training or knowledge mobilization accomplished by CBR trainees.

This is a repost of a blog written by CBR summer students Jackie Hagstrom, Mohammed Al-Seragi and Nastaran Davilu. It was edited by CBR Communications and Programs Coordinator Kaitlyn Chuong, and originally appeared on the CBR blog in September 2024. Each year, CBR’s Research Day provides an opportunity for CBR Summer Studentship Program participants to share their research projects with their peers and other labs while practicing presentation skills through short talks and poster presentations.

A look back at CBR Research Day 2024 

On August 15th, the CBR community gathered in-person and online to celebrate the hard work and research of this year’s summer students. The day kicked off with welcoming remarks, followed by oral presentations from students, where we heard from peers working on diverse projects. Each student had just 3 minutes to present their summer research projects, with the promise of a rubber chicken noise signaling if they exceeded their time limit.  

It was inspiring to learn what these four months looked like for this year’s summer students. The collection of three-minute flash talks was a striking window into the immense breadth of research behind the twenty-one-membered cohort. Everything from cancer glycoimmunology to stem cell differentiation, blood disease pathology and the like were subjects of the two-hour triage of presentations. More impressive than the research itself was how effectively everybody was able to collapse many weeks of work into a mere three minutes — something many students said they struggled with! 

 

The day provided both a platform to showcase our work and an opportunity to engage in meaningful conversations within the CBR community.

Nastaran Davilu, CBR Summer Student 2024

This year’s Neil Mackenzie Mentorship Award was presented to Dr. Michael Sutherland who spoke on what excellent mentorship means to him, as he reflected on his 20+ years of working under Dr. Ed Pryzdial. He emphasized the value of giving students actionable advice when challenges arise, the importance of empathy, comradery and being understanding and even showcased his knowledge of “brat summer”, a term he learned from his students. A particularly memorable moment was Dr. Sutherland humorously mentioning being told he has no “rizz,” and shared his experience of checking if the term was offensive, only to have Reddit users call his question “cringe.” This lighthearted moment, featuring other classic Gen-Z phrases, added humor to the day and highlighted the inclusive and fun spirit of the CBR community. 

CBR summer students pose for a group photo with keynote speaker, Dr. Brianne Kent. 

To top it off, Dr. Brianne Kent, this year’s keynote speaker, delivered a highly insightful address on the intersection of learning, sleep, and circadian rhythms with dementia and what that means for our aging and vulnerable populations. Dr. Kent began by discussing novel biomarkers that could help predict the onset age of Alzheimer’s disease (AD), which may provide patients a better chance at benefiting from treatment. One such biomarker is disturbed sleep, with research suggesting that targeting sleep disturbances could prevent up to 15% of AD cases. She explored various topics, including the potential of the antidepressant Trazodone to slow cognitive decline. Overall, this research points to slow wave sleep as a key area of therapeutic intervention and suggests that cognitive tasks assessing pattern separation are particularly sensitive to sleep disruptions and sleep aids. Maybe a bit more upending was Dr. Kent’s realization that students don’t sleep nearly as much as she thought, something that many students can attest to. 

Attendees visit the poster presentations during Research Day.

Following the keynote address, the event transitioned to the poster session in the UBC Life Sciences Centre West Atrium. The CBR community circulated and engaged in in-depth discussions with students eager to delve deeper into their research.  

Ending the day off with poster presentations was an amazing representation of the collaborative atmosphere that permeated the event. It was clear that this year’s Research Day was more than just a platform for sharing results; it was a space for building connections, exchanging ideas, and sparking new collaborations.”

Sajida Chowdhury, CBR Summer Student 2024

Poster judges provided valuable feedback, helping to explore future research directions, critiquing methodologies, and making connections to other related work happening at the CBR. With refreshments in hand, students also took the opportunity to explore their peers' posters, gaining insight into where their research paths might lead after the CBR Summer Studentship Program. The evening ended with a BBQ dinner shared with friends, families, and lab members, a fitting end to a summer filled with connections and opportunities. 

CBR Research Day was a hit in many more ways than the findings we were able to share. It was a time of learning but one of celebration as well. I have high promises for the Research Days to come and hope to be around for them too! 

Mohammed Al-Seragi, CBR Summer Student 2024

Congratulations to all of the award winners at this year’s Research Day: 

  • Best Oral Presentation (voted by the students) – Madelyn Tisdale, Mizumoto Lab 
  • People’s Choice Award (voted by the audience) – Houria Afshar Moghaddam, Av-Gay Lab 
  • Best Poster Presentation (voted by the poster judges) – Simrat Binning, Cote Lab 
Dr. Ed Conway presents the Best Oral Presentation award to Madelyn Tisdale.
Dr. Ed Conway presents the People’s Choice Award to Houria Afshar Moghaddam
Dr. Ed Conway presents the Best Poster Presentation award to Simrat Binning. 

Many thanks to our sponsors, without whom the CBR Summer Studentship Program and CBR Research Day would not be possible: the Neil Mackenzie Memorial Fund, the Naiman-Vickars Endowment Fund, Canadian Blood Services, GSK, AstraZeneca, GRIFOLS, Beigene, Stago and Sobi. We’d also like to say thank you to the Life Sciences Institute for partnering with us on this year’s program. Lastly, we are grateful for all the support and kindness of Kaitlyn Chuong, the CBR Communications and Programs Coordinator. 

More about events at the Centre for Blood Research  

  • Missed the event? Watch the recording of CBR Research Day 2024, see photos from the event and review the program on the CBR website
  • Other upcoming CBR events: Registration is now open for the 18th Annual Earl W. Davie Symposium taking place November 13, 2024. The goal of the Earl W. Davie Symposium is to disseminate advances in the field of hemostasis-thrombosis, as applied to innate immunity, infectious diseases, inflammation and cancer. The registration deadline for oral presentations is October 8th with travel awards available for trainees to attend and present at the symposium. 

Canadian Blood Services – Driving world-class innovation 

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.  

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency. 

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Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline

Canadian Blood Services research engineer applies network modelling techniques and mentorship skills to benefit Canada’s Lifeline


Tuesday, October 22, 2024 Dr. Emily Freeman

Dr. John Blake is a research engineer at Canadian Blood Services and a Professor in the Department of Industrial Engineering at Dalhousie University. Based in Halifax, Nova Scotia, Dr. Blake and his trainees use engineering principles and various computer-based optimization techniques to inform large scale decisions at Canadian Blood Services.  

Applying network modelling to biologics  

To some, it may be surprising to learn that there is such opportunity to integrate engineering into the health-care focused setting of Canadian Blood Services. However, as Dr. Blake explains, the same engineering principles that apply to the development and quality assurance of other products also apply to biologics such as blood, stem cells and organs. One of these classic engineering approaches currently applied to improving operations at Canadian Blood Services is network modelling.  

Network modelling is a computer-based method that creates a virtual representation of objects and their relation to each other. The resulting models are particularly useful for maintaining adaptability in the collection of blood donations, as well as the distribution and inventory management strategies that allow Canadian Blood Services to remain a safe and reliable provider of life-saving products. 

Dr. Blake making friends while walking the Camino de Santiago in Spain

Contributing to efficiency and sustainability in Canada’s Lifeline  

For Dr. Blake’s team, modelling is not about the data acquired but rather how they can turn existing data into real life change. Part of this approach is ensuring that Canadian Blood Services is asking the right questions when it comes to allocating resources. For example, Dr. Blake has worked on models to assess how changing stem cell donor recruitment will affect the number of matches for Canadian patients. By modelling things such as recruitment approaches, Dr. Blake’s work assists Canadian Blood Services to consistently identify ways to improve Canada’s Lifeline.

Recently, Dr. Blake has also been applying this method to optimize the number and location of mobile and permanent donor facilities across the nation. This redesign of the donation facility network will address the growing demand for donations by bringing Canadian Blood Services’ facilities closer to the donors. 

“I have waited my entire career for a problem of this type – it is truly a once in a lifetime opportunity.”

Dr. John Blake, Canadian Blood Services Research Engineer

Securing the future of Canada’s Lifeline  

To sustain a safe and effective blood system in Canada for years to come, network modelling and optimization is a never-ending process. This is one of the reasons that Dr. Blake is committed to securing the future of transfusion and transplantation systems by training and mentoring the next generation of engineers. In fact, seeing his former students join Canadian Blood Services and dedicate their talents to improving the future of Canada’s Lifeline is one of Dr. Blake’s proudest achievements.  

One of Dr. Blake’s former students, Matt Nelson, is now an industrial engineer at Canadian Blood Services.  

“In my role, I use systematic thinking to build and run complex models; collect and analyze the required data; produce useful results; and explain these results to non-technical leaders on a regular basis,” Matt says. Recently, Matt contributed to the launch and expansion of pathogen-reduced platelets, a new product that was implemented across Canadian Blood Services production sites starting in 2022. The implementation of pathogen-reduced platelets has provided an additional layer of safety for recipients by reducing the risk of potential transfusion-transmitted pathogens without compromising the quality of the component. Matt credited Dr. Blake in helping him develop the necessary skills he now dedicates to safeguarding Canada’s Lifeline:  

“Dr. Blake was the professor who introduced me to the uses of simulation to understand complex non-linear systems. This type of system is very common in situations that have a lot of variability – like the blood system – and simulation allows for exploration of the response of the system to changes.” 

Matt Nelson, Canadian Blood Services Industrial Engineer

Over the years, Dr. Blake’s ongoing modelling work and mentorship activities have also led to many recognitions and awards, but he is most proud of being recognized as Professor of the Year by Dalhousie Undergraduate students, and with awards for his contributions to the Canadian Operational Research Society. He has even the earned the distinction of being Dalhousie’s first engineer to be awarded grant funding from the tri-council agency, Social Sciences and Humanities Research Council (SSHRC). 

“I am proud to work on projects that have a measurable impact on people’s health and well-being,” Dr. Blake says. “I am forever grateful to Dr. Dana Devine for first giving me the opportunity to serve Canadians in this role at Canadian Blood Services.” 


Canadian Blood Services – Driving world-class innovation

Through discovery, development and applied research, Canadian Blood Services drives world-class innovation in blood transfusion, cellular therapy and transplantation—bringing clarity and insight to an increasingly complex healthcare future. Our dedicated research team and extended network of partners engage in exploratory and applied research to create new knowledge, inform and enhance best practices, contribute to the development of new services and technologies, and build capacity through training and collaboration. Find out more about our research impact.   

The opinions reflected in this post are those of the author and do not necessarily reflect the opinions of Canadian Blood Services nor do they reflect the views of Health Canada or any other funding agency.  

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Tuesday, March 29, 2022
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This post was written by Marie-Soleil Smith, PhD Candidate in Dr. Hélène Côté’s Lab at the University of British Columbia, and edited by Dr. Geraldine Walsh, knowledge broker at Canadian Blood Services. It originally appeared on the Centre for Blood Research blog in March 2022.


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