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Nucleic acid detection with single-base specificity integrating isothermal amplification and light-up aptamer probes

Nanoscale, 2024, 16,20067-20072
DOI: 10.1039/D4NR01638F, Communication
Jaekyun Baek, Jihyun Park, Youngeun Kim
CLASSIC is a label-free DNA detection platform with single-nucleotide specificity and attomolar sensitivity. This assay offers rapid and sequence-specific DNA analysis through single-strand conversion and split light-up aptamer probes.
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Correction: Ce6-Conjugated and polydopamine-coated gold nanostars with enhanced photoacoustic imaging and photothermal/photodynamic therapy to inhibit lung metastasis of breast cancer

Nanoscale, 2024, 16,20354-20355
DOI: 10.1039/D4NR90194K, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ziwei Li, Fan Yang, Di Wu, Yanhong Liu, Yang Gao, Haichen Lian, Hongxin Zhang, Zhibin Yin, Aiguo Wu, Leyong Zeng
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other

Applications of nanotheranostics in the second near-infrared window in bioimaging and cancer treatment

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03058C, Review Article
Huimin Li, Pengju Li, Jiarui Zhang, Ziyi Lin, Lintao Bai, Heyun Shen
This review summarized the application of the second near-infrared nano-platform in the field of nano-agents design, optical imaging and cancer treatment, aiming at providing profound insights into its development status and future challenges.
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A microneedle patch realizes weight loss through photothermal induction of fat browning

Biomater. Sci., 2024, 12,1726-1737
DOI: 10.1039/D3BM01767B, Paper
Zichun Gao, Yixuan Liu, Wenjiao Lin, He Lian, Zhaoxu Meng
Hyaluronic acid microneedles loaded with polydopamine nanoparticles induce fat browning, offering innovative localized obesity treatment.
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other

Sorafenib and tetrakis (4-carboxyphenyl) porphyrin assembled nanoparticles for synergistic targeted chemotherapy and sonodynamic therapy of hepatocellular carcinoma

Biomater. Sci., 2024, 12,1864-1870
DOI: 10.1039/D3BM01994B, Paper
Yongzhi Chen, Qiuxia Tan, Yuanyu Tang, E. Pang, Rui Peng, Minhuan Lan, Dousheng Bai
Hepatocellular carcinoma (HCC) is characterized by a high degree of malignancy and mortality.
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other

Light-inducible nanodrug-mediated photodynamic and anti-apoptotic synergy for enhanced immunotherapy in triple-negative breast cancer

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00083H, Paper
Jing Huang, Xingliang Liu, Minzhao Lin, Zecong Xiao, Xintao Shuai
An ROS-labile nanodrug co-encapsulating Ce6 and a Bcl-2 inhibitor enabled PDT and reversed apoptotic resistance, demonstrating a potent inhibitory effect on tumor growth.
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A mitochondria-targeting heptamethine cyanine-chlorambucil formulated polymeric nanoparticle to potentiate native tumor chemotherapeutic efficacy

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00003J, Paper
Jing Liu, Jie Zhang, Yongteng Zhang, Wei Wei, Meixiao Zhan, Zhiren Zhang, Bing Liu, Xianglong Hu, Weiling He
Facile conjugation of chlorambucil with IR775 chloride can afford IR775-Cbl with mitochondria-targeting potency for tumor cells, exhibiting distinct “1 + 1 > 2” tumor inhibition.
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Photothermal therapy: a novel potential treatment for prostate cancer

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00057A, Review Article
Zirui Dong, Kaming Xue, Anushikha Verma, Jian Shi, Zhihao Wei, Xiaotian Xia, Keshan Wang, Xiaoping Zhang
This review discussed photothermal therapy from basic information to its circumstances and potential in protate cancer treatment.
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Bioinspired ginsenoside Rg3 PLGA nanoparticles coated with tumor-derived microvesicles to improve chemotherapy efficacy and alleviate toxicity

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00159A, Paper
Shulei Zhang, Bo Zheng, Yiqi Wei, Yuhao Liu, Lan Yang, Yujiao Qiu, Jing Su, Mingfeng Qiu
Breast cancer, a pervasive malignancy affecting women, demands a diverse treatment approach including chemotherapy, radiotherapy, and surgical interventions.
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Telomerase: a nexus between cancer nanotherapy and circadian rhythm

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00024B, Minireview
Pramit Kumar Ghosh, Maddila Jagapathi Rao, Chandra Lekha Putta, Sandipan Ray, Aravind Kumar Rengan
The use of nanoparticles for identifying and suppressing telomerase presents promising opportunities for anticancer strategies, particularly in relation to circadian regulation.
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Optimization of lipid assisted polymeric nanoparticles for siRNA delivery and cancer immunotherapy

Biomater. Sci., 2024, 12,2057-2066
DOI: 10.1039/D3BM02071A, Paper
Song Lin, Houjin Jing, Xiaojiao Du, Xianzhu Yang, Jun Wang
A siRNA delivery system was developed using clinically approved mPEG-b-PLGA, cationic lipid and ionizable lipid for siRNA delivery and cancer immunotherapy.
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A universal strategy to enhance photothermal conversion efficiency by regulating the molecular aggregation states for safe photothermal therapy of bacterial infections

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00412D, Paper
Hao Fu, Yongxin Zhang, Cheng Wang, Zhencheng Sun, Shuyi Lv, Minghui Xiao, Kaiyu Wu, Linqi Shi, Chunlei Zhu
A universal strategy is developed to remarkably enhance the photothermal conversion efficiency of photothermal materials. This advancement enables effective treatment of drug-resistant bacterial infections through safe photothermal therapy.
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Other letters than A-Z in Word Counter?

Hello!

Regarding this article/app: https://css-tricks.com/build-word-counter-app/

Maybe I have missed something, but how would I go about including other, foreign letters? I am Swedish, so I would like the app to be able to hande these: ÅÄÖ/åäö.

Right now, writing one of these letters will split up the word and count it as two. For example, the Swedish word “bäbis” (baby) counts as two words, and the keyword just becomes “bis”.

Would be super thankful for any help here. ELI5 :)

/David




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Four gadgets to gift your mum on Mother’s Day 2024 

Going way beyond the obvious - perfumes, clothes and flowers - here are six cool gadgets you can consider giving her on this special day




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Delhi IAS coaching centre deaths: Four institutes offer ₹10 lakh each to kin of victims, free classes to others

Civil services aspirants, who have been protesting over the deaths of the three students, called the compensation a gimmick, and a strategy to dilute the issue




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'Rajinikanth is god, other actors are devotees'

'Top actors came to me while Kabali was being shot, to ask me to cast them in at least one scene with Thalaivar -- even if it required them to clean a table on the side while Thalaivar is in the shot.' Kabali producer Kalaipuli S Thanu tries to explain the Rajinikanth phenomenon.




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Will Mohanlal's Villain be another Mersal?

'Keeping quiet is not an option for me. It should not be an option for anyone. If you have a voice, you must use it.' Tamil actor Vishal speaks out.




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Another South Film BEATS Bollywood!

Karthikeya 2 seems to have arrived out of nowhere and is turning out to be the top performing film of the weekend, and that too, in its second week of release.




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'A Mother Is The Backbone Of A Family'

Actors share adorable moments with their mums on Mother's Day.




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Sportsmen have a platform — some use it well, others waste it

In a country of a billion and a half, you can’t make a statement without millions finding fault with it. Social media trolls are a menace, so players keep out of their way.




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Laxman’s 281 and other cricket feats that speak for special players

Every player is capable of one moment of greatness in a career, but the best players have many of them, and closer together.




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Column | The other Ayodhya

The story of Ram travelled across the seas, and Thailand’s erstwhile capital Ayutthaya is proof




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India rely on the kindness of others as WTC final dreams fade

The recurring, and humiliating collapses of India’s batting are at least partially the responsibility of the cricket board which showed a lack of spine by not insisting that the big boys play in the national championship.




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Apple iPhone 15: Pricing in India versus other countries

Apple’s iPhone 15 series includes iPhone 15, iPhone 15 Plus, iPhone 15 Pro, and iPhone 15 Pro Max




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Apple reports another record quarter in India driven by iPhone sales

Reports double digit revenue growth in the quarter, Apple shipments cross 10-million mark




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Mother’s unintended prophecy

Surviving Self-Distancing – Day 7




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OnePlus 13 to launch on October 31: Hasselblad tuned camera and other features to expect

The teaser shows three colour options for the OnePlus 13 Chinese buyers




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Qualcomm unveils Snapdragon 8 Elite chip for AI, signs Samsung and others

The company has also re-worked the parts of the chip, which is called the Snapdragon 8 Elite, to handle tasks such as generating images and text




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Telangana Govt in talks with BCCI to build another international cricket stadium

Addressing the Assembly on Friday, the CM said that the Government would provide land if the BCCI agreed to build a stadium with international standards




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Amid victory spree at 45th Chess Olympiad, here’s a recap of Dommaraju Gukesh’s other win - businessline’s Young Changemaker award

Gukesh’s grandparents, Usha and Shankar Raju, received the award on behalf of the 18-year old, who is representing India at the Chess Olympiad




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Lilly boosts immunotherapy pipeline with Armo BioSciences acquisition

The drug company will pay $1.6 billion to gain Armo’s IL-10 program




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The difficult search for the right recipe in cancer immunotherapy

With so many ingredients on hand, can the oncology community figure out how to sensibly and efficiently combine checkpoint inhibitors with other drugs?




other

Drug service provider Alcami to go to another private equity firm

New investor takes on a company trying to combine a range of pharmaceutical services




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Drug service provider Alcami to go to another private equity firm

New investor takes on a company trying to combine a range of pharmaceutical services




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Setup may make transferring <em>tert</em>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




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Setup may make transferring <i>tert</i>-butyl lithium and other pyrophoric reagents safer

Simple pieces of equipment decrease the danger of moving small volumes of chemicals prone to igniting




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Synthesizing mothers’ milk

Scientists are seeking ways to make beneficial but elusive sugars found in breast milk




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Heat-stable peptide might save thousands of mothers from excessive bleeding after childbirth

Massive clinical trial including developing nations demonstrates carbetocin is no less effective or safe than oxytocin




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Italmatch is sold by one private equity firm to another





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BMW X4 lords over other cars on the road

The X4 offers an imposing presence that you cannot miss even in a crowd of other cars, says Pavan Lall.




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Carens is another arrow in Kia's packed quiver

The Carens is a warning for cars such as the Tata Safari, Hyundai Alcazar, Maruti Ertiga, Toyota Innova Crista and Mahindra XUV 700, because Kia punches much harder than others in its weight category.




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The Rs 4.5-cr Roma is a departure from other Ferraris

'La Nuova Dolce Vita' is the tagline of Ferrari's Roma which translates into 'The New Good Life'.The Roma is a Ferrari GT (Grand Touring) sports car and is also part of their entry-level lineup but it is everything but entry-level.This Rs 4.5 crore (on-road, Mumbai) performance machine is an all-new Prancing Horse that is visually striking, high on tech and being a Ferrari, offers thrilling performance that will excite your senses.




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XGIMI Horizon Pro review: The projector that transports you to another world

The XGIMI Horizon Pro is impressive, sleek, and like a TV without the physical screen




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The companion species manifesto [electronic resource] : dogs, people, and significant otherness / Donna Haraway.

Chicago : Prickly Paradigm Press, [2003]




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Q2 Results Highlights: SBI, LIC, Tata Motors, Ashok Leyland, MRF, Ola Electric, others

Q2 Results 2024 Updates: Here are the updates on the Q2 financial results of some of India’s major companies, including State Bank of India, Life Insurance Corporation of India, Tata Motors, Power Finance Corporation, Ashok Leyland, MRF, Ola Electric Mobility, and others. These results offer critical insights into each company’s performance and market outlook, impacting sectors such as banking, automotive, and electric mobility. Follow along for the latest details on revenue, profit margins, growth strategies, and industry trends as companies announce their quarterly performance.




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Kolkata doctor rape and murder: Junior doctors’ hunger strike enters 10th day; another protesting medic hospitalised

“A medical staff is in the CCU and his parameters have deteriorated. We have formed a medical board to treat him,” a senior doctor of the NRS Medical College and Hospital told




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Fire at Kolkata Hospital, 80 patients shifted to other health facilities

Family members of a cancer patient who passed away later in the day, alleged that the death was due to inhaling of smoke due to the fire.




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Mamata Banerjee reaches out to estranged brother on Bhai Phonta

The Trinamool Congress chairperson had in March this year said that she was disowning and snapping ties with her younger brother Swapan Banerjee after he expressed desire to contest from Howrah in the 2024 Lok Sabha election despite the party fielding Prasun Banerjee from the constituency




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Postliminary treatment of food-waste digestate via combined hydrothermal carbonization and microbial fuel cell for bio-energy recovery: a comparative life cycle impact assessment

Green Chem., 2024, Advance Article
DOI: 10.1039/D4GC04081C, Paper
Shraddha Yadav, Manikanta M. Doki, Makarand M. Ghangrekar, Brajesh K. Dubey
Multiple resource recovery from food-waste digestate by deploying hydrothermal carbonisation and microbial fuel cells. A green route for environmental sustainability and economic gains.
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