Dementia -- Treatment.

Embroidery.

Library administration.

London : Cassell, 1901.

London : Cassell, 1894.

London : Cassell, 1898.

London : Cassell, 1902.

London : Smith, Elder, 1887.

As Oklahoma teachers prepare for day four of their statewide walkout, here's a guide to the larger picture of teacher protests.

New York : Experimental Manpower Laboratory at Mobilization for Youth, Inc., [1971]

[Dorchester] : Dorset Community NHS Trust, 1997.

Lin Liu, Yuqi Qiu, Loki Natarajan, Karen Messer.

Source: The Annals of Applied Statistics, Volume 13, Number 3, 1370--1396.

Abstract:
It is common to encounter missing data among the potential predictor variables in the setting of model selection. For example, in a recent study we attempted to improve the US guidelines for risk stratification after screening colonoscopy ( Cancer Causes Control 27 (2016) 1175–1185), with the aim to help reduce both overuse and underuse of follow-on surveillance colonoscopy. The goal was to incorporate selected additional informative variables into a neoplasia risk-prediction model, going beyond the three currently established risk factors, using a large dataset pooled from seven different prospective studies in North America. Unfortunately, not all candidate variables were collected in all studies, so that one or more important potential predictors were missing on over half of the subjects. Thus, while variable selection was a main focus of the study, it was necessary to address the substantial amount of missing data. Multiple imputation can effectively address missing data, and there are also good approaches to incorporate the variable selection process into model-based confidence intervals. However, there is not consensus on appropriate methods of inference which address both issues simultaneously. Our goal here is to study the properties of model-based confidence intervals in the setting of imputation for missing data followed by variable selection. We use both simulation and theory to compare three approaches to such post-imputation-selection inference: a multiple-imputation approach based on Rubin’s Rules for variance estimation ( Comput. Statist. Data Anal. 71 (2014) 758–770); a single imputation-selection followed by bootstrap percentile confidence intervals; and a new bootstrap model-averaging approach presented here, following Efron ( J. Amer. Statist. Assoc. 109 (2014) 991–1007). We investigate relative strengths and weaknesses of each method. The “Rubin’s Rules” multiple imputation estimator can have severe undercoverage, and is not recommended. The imputation-selection estimator with bootstrap percentile confidence intervals works well. The bootstrap-model-averaged estimator, with the “Efron’s Rules” estimated variance, may be preferred if the true effect sizes are moderate. We apply these results to the colorectal neoplasia risk-prediction problem which motivated the present work.

Everything we do at FAO aims at ensuring a better future. Sure, we need to tackle the huge food and environmental challenges we face today. But we always keep an eye on what that means for tomorrow. More than just quick fixes, we look for sustainable solutions that will benefit generations to come. The future of our world depends on today’s [...]

Pizza and pasta are pretty obviously out, but what are the other no-nos?

The following is a guest post by Katherine Blood, Curator of Fine Prints, Prints & Photographs Division. As the Library of Congress marks its 220th year of serving the nation, the publication of a new guide tells two stories: how staff have for decades worked with art professionals to build the collections and how by […]

Canadian figure skater Scott Moir posted a video on Instagram and Twitter on Thursday, explaining that he and fiancee Jackie Mascarin are currently stationed in Tampa, Fla., because Mascarin works as a physician's assistant in the respiratory unit of a local hospital.

Major League Soccer is easing its training restrictions, allowing clubs to use their practice fields but only for individual workouts and under strict rules.

The Vancouver Whitecaps said it has ordered two player to self-quarantine for 14 days after they violated club and league orders to abide by physical distancing guidelines in B.C.

The federal government is looking to hire paramedics who can fly up to remote First Nations in case there’s a surge of COVID-19 cases, and officials say it’s evidence of a different approach to Indigenous health care than during the H1N1 outbreak.

Documents created by the top disease investigators in the U.S. meant to give step-by-step advice to local leaders deciding when and how to reopen public places such as mass transit, day care centres and restaurants during the still-raging pandemic have been shelved by the Trump administration.

THOSE last times.... we all of us have memories our minds keep running back to in these social distancing times. The last time we gathered, last time we swam together, the last drive to a beach. One of mine is the post-swim hot tub at the Scottish Winter Swimming Championships in the chilly waters of Loch Tay – around 30 of us crammed in there, many in fancy dress, some in swim make-up, a great, crowded bath of joy.

IT'S the day after May Day and perhaps you’re feeling you’ve missed out on a good, sweaty Scottish pagan spring ritual of the type done particularly well at Beltane on Edinburgh’s Calton Hill, though not in a year of quarantine. Never fear. There are still ways of channelling the fertility rites of spring, the chief one being, of course, the folk horror classic The Wicker Man. Put on a goat mask, get in touch with your inner Wicker – or even Wicca – and revel in a bit of self-isolation

Baker’s Delight

LOCKDOWN may start easing soon, but it seems likely to be a long time yet before any of us find ourselves in an actual physical pub. It’s not of course the booze we’re missing – we can get plenty of that – but the company, the conviviality, the atmosphere, the feeling that, in the late hours, almost anything might kick off. So, for those who cry inside every time they walk past their closed-down local, or wake-up having dreamed of standing with a pint at the bar, here’s a few ways you

Small but beautiful, the UEFA Regions' Cup kicks off in Turkey at the weekend; get the inside line on the world's top amateur tournament and the contenders for the 2017 crown.

Effective management approaches are not skills principals typically learn through the traditional pathways of education. To fill the gap, they are turning to business programs and publications.

“THE little island of Todday is a completely isolated community,” declares the voiceover at the start of the 1949 Ealing Studios classic Whisky Galore. “100 miles from the mainland, 100 miles from the nearest cinema or dancehall. Oh, but the islanders know how to enjoy themselves. They have all that they need. But in 1943, disaster overwhelmed this little island. Not famine, nor pestilence, nor Hitler’s bombs, or the hordes of an invading army, but something far, far worse: ‘There is n

Rather than adhering to a specific curriculum, families who "unschool" believe learning happens naturally and should be driven by a student's interests. Education Week spent a "school" day with the Matica family to see this decades-old approach to home schooling in action.

Community-acquired pneumonia (CAP) is a common pediatric illness caused by Streptococcus pneumoniae. New pediatric Infectious Diseases Society of America CAP guidelines are now available recommending ampicillin as empirical treatment of children hospitalized with uncomplicated CAP.

This study found that a CAP guideline led to an increase in the narrow-spectrum antibiotic ampicillin. Additionally, an increase in the use of amoxicillin at discharge was observed. Furthermore, change in therapy did not lead to increased adverse outcomes. (Read the full article)

Adherence to guidelines has generally been shown to improve patient care and reduce the cost of care. Current understanding of the varying reasons why clinicians deviate from guidelines is based on surveys and retrospective reviews.

We examined clinician deviations from guidelines in a prospective fashion and attempted to categorize those deviations. Better elucidation of clinician reasoning behind deviations may inform care improvement and help define strategies to eliminate unjustifiable deviations. (Read the full article)

Adherence to Pediatric Advanced Life Support resuscitation guidelines for children with sepsis is low; however, few studies have been conducted in the tertiary care emergency department setting.

Adherence to septic shock guidelines in a tertiary care pediatric emergency department is low. Adherence to fluid guidelines and the entire PALS algorithm was associated with a shorter hospital length of stay. (Read the full article)

There are limited data on current testing and treatment patterns for children hospitalized with pneumonia, and on whether institutional guidelines affect care.

The use of institutional clinical practice guidelines was not associated with changes in diagnostic testing, hospital length of stay, or costs for children hospitalized with pneumonia, but was associated with increased use of narrow-spectrum antibiotics. (Read the full article)

There is a lack of consensus regarding the optimal investigative approach after a first febrile urinary tract infection. This is because of uncertainty regarding the long-term clinical significance of vesicoureteral reflux and urinary tract infection–related renal scarring.

No ideal diagnostic algorithm exists. We found marked variability in sensitivity and specificity for detection of abnormalities using current protocols. We also highlight the considerable cost differences, both financially and in terms of radiation dose, of different protocols. (Read the full article)

Expectations are high that electronic health record–based clinical decision support and performance feedback will improve adherence to guidelines by delivering relevant and actionable information to clinicians. Few studies have evaluated these assertions or examined the combined effects of decision support and feedback.

Clinical decision support customized to a patient’s history and presentation and performance feedback are both effective for improving adherence to guidelines for otitis media. However, the combination of the 2 interventions is no better than either delivered alone. (Read the full article)

In the only previous cross-sectional study, the quality of pediatric guidelines was rated low on the AGREE-II (Appraisal of Guidelines for Research and Evaluation II) scale. The levels of evidence used in pediatric clinical practice guidelines have never been described.

American Academy of Pediatrics guidelines score low on the AGREE-II scale. Approximately one-quarter of recommendations are based on expert opinion or no reference. These findings support the adoption of standards for guideline development and research targeted toward unsupported recommendations. (Read the full article)

Clinic-based weight control programs for pediatric obesity are time and personnel intensive and not accessible to a large proportion of the population.

This is the first study to reveal the efficacy of a low-intensity, 5-month, guided self-help treatment of childhood obesity with effects on the target child’s weight immediately posttreatment and 6 months later. (Read the full article)