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Boron-based nanosheets for combined cancer photothermal and photodynamic therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00070A, Paper
Yong Kang, Xiaoyuan Ji, Zhengjun Li, Zhiguo Su, Songping Zhang
Tumor phototherapy is of great significance for the expansion and advancement of cancer treatment methods.
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Nanoscale dual-enzyme cascade metal–organic frameworks through biomimetic mineralization as ROS generators for synergistic cancer therapy

J. Mater. Chem. B, 2020, Advance Article
DOI: 10.1039/D0TB00357C, Paper
Shuiling Jin, Lanling Weng, Zhi Li, Zhenzhen Yang, Lili Zhu, Jianxiang Shi, Wenxue Tang, Wang Ma, Hong Zong, Wei Jiang
Chemodynamic therapy (CDT) has been critically challenged by insufficient H2O2 in cancer tissues and inefficient reactive oxygen species (ROS) production.
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Coaxial mussel-inspired biofibers: Making of a robust and efficacious depot for cancer drug delivery

J. Mater. Chem. B, 2020, Accepted Manuscript
DOI: 10.1039/D0TB00052C, Paper
Javad Foroughi, Sepehr Talebian , In Kyoung Shim, Kara Vine, Song Cheol Kim, Geoffrey M Spinks
Biopolymer-based hydrogels have emerged as promising platforms for drug delivery systems (DDSs) due to their inherent biocompatibility, tunable physical properties and controllable degradability. Yet, drug release in majority of these...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Dapsone exposure and Australian Vietnam service : mortality and cancer incidence / [E.J Wilson, K.W Horsley, R. van der Hoek]




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Social media helps charity to monitor the flow of blood cancer conversations

For more than 56 years the charity I work for, Bloodwise, has been working to beat blood cancer, the third most fatal form of cancer. In our work, we have had to constantly evolve and adapt to meet the ever-changing needs of our supporters and patients.

Unsurprisingly, the rise of digital channels has been transformational for us, from the delivery of patient information online to communicating with supporters via social media. However, as the importance of digital grew, we knew we needed to use data and insight to understand our online audiences better and measure our performance.

complete article




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[ASAP] Proteomics Analysis of Formalin Fixed Paraffin Embedded Tissues in the Investigation of Prostate Cancer

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00587




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[ASAP] Parallel Reaction Monitoring-Mass Spectrometry (PRM-MS)-Based Targeted Proteomic Surrogates for Intrinsic Subtypes in Breast Cancer: Comparative Analysis with Immunohistochemical Phenotypes

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00490




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[ASAP] Bioinformatics Analysis of Metabolomics Data Unveils Association of Metabolic Signatures with Methylation in Breast Cancer

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.9b00755




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[ASAP] SWATH-MS Analysis of FFPE Tissues Identifies Stathmin as a Potential Marker of Endometrial Cancer in Patients Exposed to Tamoxifen

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00064




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[ASAP] Comparative Glycomic Analysis of Exosome Subpopulations Derived from Pancreatic Cancer Cell Lines

Journal of Proteome Research
DOI: 10.1021/acs.jproteome.0c00200




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Combined Raman and AFM detection of changes in HeLa cervical cancer cells induced by CeO2 nanoparticles – molecular and morphological perspectives

Analyst, 2020, Advance Article
DOI: 10.1039/C9AN02518A, Paper
Mirjana Miletić, Sonja Aškrabić, Jan Rüger, Borislav Vasić, Lela Korićanac, Abdullah Saif Mondol, Jan Dellith, Jürgen Popp, Iwan W. Schie, Zorana Dohčević-Mitrović
Raman and AFM analyses represent a tool for the evaluation of cytotoxic and anti-proliferative effects in cells induced by CeO2 nanoparticles.
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Profiling of immune-cancer interactions at the single cell level using microfluidic well array

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00110D, Paper
Honglei Tu, Zhuhao Wu, Yu Xia, Hui Chen, Hang Hu, Zhao Ding, Fuling Zhou, Shishang Guo
Cancer immunotherapy has achieved great success in hematological cancers. However, immune cells are highly heterogeneous population and can vary highly on clonal expansion, migration and function status, making it difficult...
The content of this RSS Feed (c) The Royal Society of Chemistry




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An electrochemical sensor based on enzyme-free recycling amplification for sensitive and specific detection of miRNAs from cancer cells

Analyst, 2020, 145,3353-3358
DOI: 10.1039/D0AN00275E, Paper
Lili Jiang, Yuling Yang, Yuhong Lin, Ziyi Chen, Chao Xing, Chunhua Lu, Huanghao Yang, Shusheng Zhang
A catalyzed hairpin assembly and binding-induced formation of the DNA three-way junction for ultrasensitive electrochemical detection of diverse miRNAs is reported.
The content of this RSS Feed (c) The Royal Society of Chemistry




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In situ multiplex detection of serum exosomal microRNAs using an all-in-one biosensor for breast cancer diagnosis

Analyst, 2020, 145,3289-3296
DOI: 10.1039/D0AN00393J, Paper
Huizhen Wang, Dinggeng He, Kejing Wan, Xiaowu Sheng, Hong Cheng, Jin Huang, Xiao Zhou, Xiaoxiao He, Kemin Wang
Herein, a simple all-in-one biosensor based on a DNA three-way junction has been constructed for in situ simultaneous detection of multiple miRNAs by competitive strand displacement.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Plasmonic Nanobiosensors for Detection of MicroRNA Cancer Biomarkers in Clinical Samples

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/D0AN00193G, Paper
Bridget M Crawford, Hsin-Neng Wang, Christina Stolarchuk, Richard Von Furstenberg, Pietro Strobbia, dadong zhang, xiaodi qin, kouros owzar, katherine garman, Vo-Dinh Tuan
MicroRNA (miRNA) play an important role in the regulation of biological processes and have demonstrated great promise as biomarkers for the early detection of various diseases, including esophageal adenocarcinoma (EAC)...
The content of this RSS Feed (c) The Royal Society of Chemistry




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A paper-supported sandwich immunosensor based on upconversion luminescence resonance energy transfer for the visual and quantitative determination of a cancer biomarker in human serum

Analyst, 2020, Accepted Manuscript
DOI: 10.1039/C9AN02307K, Paper
Mengyuan He, Ning Shang, Lin Shen, Zhi-hong Liu
In this paper, a paper-supported analytical device based on a sandwich immunoreaction and luminescence resonance energy transfer (LRET) was reported for the visual and quantitative determination of a cancer biomarker,...
The content of this RSS Feed (c) The Royal Society of Chemistry




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[ASAP] Synthesis and Structure–Activity Relationships of Arylsulfonamides as AIMP2-DX2 Inhibitors for the Development of a Novel Anticancer Therapy

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b01961




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[ASAP] Treating Cancer by Spindle Assembly Checkpoint Abrogation: Discovery of Two Clinical Candidates, BAY 1161909 and BAY 1217389, Targeting MPS1 Kinase

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.9b02035




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[ASAP] Structure–Activity Relationship of SPOP Inhibitors against Kidney Cancer

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00161




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[ASAP] Dual-Target Inhibitors Based on HDACs: Novel Antitumor Agents for Cancer Therapy

Journal of Medicinal Chemistry
DOI: 10.1021/acs.jmedchem.0c00491




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[ASAP] Cancer Immunotherapy through the Inhibition of Diacylglycerol Kinases Alpha and Zeta

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00118




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[ASAP] Inhibitors of Hypoxia-Inducible Factors as Treatment for Cancer

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00116




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[ASAP] Characterization of an Alginate Encapsulated LS180 Spheroid Model for Anti-colorectal Cancer Compound Screening

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00076




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[ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.9b00639




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[ASAP] Potential Cancer Treatment by Agonists of the Stimulator of Interferon Genes

ACS Medicinal Chemistry Letters
DOI: 10.1021/acsmedchemlett.0c00117




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Host-guest interaction based supramolecular photodynamic therapy system: a promising candidate in the battle against cancer

Chem. Commun., 2020, Accepted Manuscript
DOI: 10.1039/D0CC02001J, Feature Article
Kui Yang, Zhihua Zhang, Jie Du, Wei Li, Zhichao Pei
Owing to its spatiotemporal selectivity and noninvasive nature, photodynamic therapy (PDT) has become a promising approach for the treatment of cancer. However, the non-targeting capability and the accompanying side effects...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Deep imaging for visualizing nitric oxide in lipid droplets: discovering the relationship between nitric oxide and resistance to cancer chemotherapy drugs

Chem. Commun., 2020, Advance Article
DOI: 10.1039/D0CC01856B, Communication
Miantai Ye, Wei Hu, Meng He, Chenchen Li, Shuyang Zhai, Zhihong Liu, Yanying Wang, Huijuan Zhang, Chunya Li
A near-infrared two-photon fluorescent probe for selective detection and deep-depth imaging of NO helps to discover the relationship between NO and resistance to antitumor drugs.
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Al centre-powered graphitic nanozyme with high catalytic efficiency for pH-independent chemodynamic therapy of cancer

Chem. Commun., 2020, Advance Article
DOI: 10.1039/D0CC01331E, Communication
Jun Li, Ke Yi, Yanli Lei, Zhihe Qing, Zhen Zou, Yuedong Zhang, Haiyan Sun, Ronghua Yang
In this work, an Al centre-powered graphitic nanozyme (Fe/Al-GNE) was developed for chemodynamic cancer therapy, which afforded pH-independent catalytic activity and high reaction kinetics.
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Potentiating anti-cancer chemotherapeutics and antimicrobials via sugar-mediated strategies

Mol. Syst. Des. Eng., 2020, Advance Article
DOI: 10.1039/C9ME00175A, Minireview
Sneha Sree Mullapudi, Debirupa Mitra, Min Li, En-Tang Kang, Edmund Chiong, Koon Gee Neoh
This article reviews the design considerations behind sugar-mediated strategies for potentiating the efficacy of drugs/photosensitizers in cancer treatment, and antimicrobials.
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Antitumor effects of novel nickel-hydrazone complexes in lung cancer cells

New J. Chem., 2020, Accepted Manuscript
DOI: 10.1039/D0NJ00921K, Paper
Damir Safin, Burak AY, Onur ŞAHİN, Burcu Saygideğer Demir, Yasemin Saygideger, José Maria López-de-Luzuriaga, Ghodrat Mahmoudi
In this work we have synthesized and characterized two new mononuclear nickel(II) complexes [NiLI]∙CH3CN (1∙CH3CN) and [Ni(H2LII)(NCS)2]∙0.5H2O (2∙0.5H2O), fabricated from a mixture of Ni(NO3)2 and KNCS with N',N'''-(1,2-diphenylethane-1,2-diylidene)di(picolinohydrazide) (H2LI) and...
The content of this RSS Feed (c) The Royal Society of Chemistry




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Changes in Trends in Thyroid Cancer Incidence in the United States, 1992 to 2016

This study uses Surveillance, Epidemiology, and End Results (SEER) registry data to describe trends in thyroid cancer incidence overall and by tumor size in the United States from 1992 to 2016.




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Incidence of Hypoparathyroidism After Thyroid Cancer Surgery in South Korea, 2007-2016

This study uses South Korean administrative database data to assess changes in incidence of postthyroidectomy hypoparathyroidism during a period of fluctuations in thyroid cancer screening and surgery between 2007 and 2016.




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Clinical oncology : cancer - diagnosis, treatment & prognosis, 21-25 May 1984 : venue, the Stephen Roberts Lecture Theatre, University of Sydney

University of Sydney. Post-Graduate Committee in Veterinary Science




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Cancer: That Painful and Lingering Disorder

Options for cancer detection and treatment were few in the 18th century. Medical Historian Sharon Cotner lays out some of the common practices in this week’s show.




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Handbook of magnetic resonance spectroscopy in vivo : MRS theory, practice and applications / editors, Paul A. Bottomley (Johns Hopkins University, Baltimore, MD, USA), John R. Griffiths (Cancer Research UK, Cambridge Research Institute, Cambridge, UK)




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Tejpal sexual assault case is like cancer on brand Tehelka

In an interview to Rajdeep Sardesai, Brand Strategist Harish Bijoor says that the sexual assault charges against founder-editor Tarun Tejpal is like a cancer on the brand Tehelka. He says that Tehelka can be revived if it brings a white paper on this...




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Punjab''s cancer belt finds antidote in its dense cover of neem

While Punjab''s Malwa belt is witnessing rising incidence of cancer - largely due to addiction to alcohol and tobacco...




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Nanotechnology-based targeted drug delivery systems for lung cancer / edited by Prashant Kesharwani

Barker Library - T174.7.N37347 2019




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El-P Drops Cancer for Cure at SXSW

EL-P talks about his new album which features Killer Mike, Danny Brown, and Mr. Muthafuckin' eXquire.  Cancer for Cure comes out on May 22nd on Fat Possom Records.




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Teen Technorati - He's Only 17 Years Old, But He's Well On His Way to Curing Cancer

Seventeen-year-old Thomas Hunt isn't old enough to vote, but he's conducting research that may one day cure cancer. Get to know the Thiel Fellow, take a tour of the lab where he's working to help make history, and find out what inspired him to get involved in cancer research.




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Teen Technorati - Teenage Wunderkinds Explain How They Got Into Cancer Research, Astrophysics & Product Design

What inspires a 17-year-old to go into cancer research or a 19-year-old to develop an obsession with astrophysics? Find out, as the 2014 Thiel Fellows explain how they first discovered their passions and why they've decided to turn them into careers.




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So Cellphones Cause Cancer, Right? That Ain't What Science Says

Your grandparents might have warned you that cellphones cause brain cancer. Well, that's not at all what science says.




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How One NY Company Is Changing Cancer Treatment | WIRED Brand Lab

BRANDED CONTENT | Produced by WIRED for Empire State Development | OmniSeq, a cancer diagnostic laboratory in upstate New York has developed an innovative genetic analysis pipeline to help match patients' tissue samples with the most effective cancer treatments currently available. In fact, their testing is so efficient that their tissue success rate is nearly 15% higher than other companies.




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Enhancing the chemotherapeutic efficacy of platinum prodrug nanoparticles and inhibiting cancer metastasis by targeting iron homeostasis

Nanoscale Horiz., 2020, Advance Article
DOI: 10.1039/D0NH00148A, Communication
Fang Ding, Lingpu Zhang, Hao Chen, Haiqin Song, Shiguo Chen, Haihua Xiao
Combination of cisplatin prodrug nanoparticles and Dp44mT results in enhanced anticancer and anti-metastatic efficiencies.
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Efficient near-infrared photosensitizer with aggregation-induced emission characteristics for mitochondria-targeted and image-guided photodynamic cancer therapy

Mater. Chem. Front., 2020, Advance Article
DOI: 10.1039/D0QM00170H, Research Article
Hanxiao Yang, Jiabao Zhuang, Nan Li, Yue Li, Shiyu Zhu, Jiaxin Hao, Jiayao Xin, Na Zhao
A highly efficient near-infrared photosensitizer with aggregation-induced emission characteristics was developed for mitochondria-targeted and image-guided photodynamic cancer therapy.
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Intervaginal space injection of a liquid metal can prevent breast cancer invasion and better-sustain concomitant resistance

Mater. Chem. Front., 2020, 4,1397-1403
DOI: 10.1039/C9QM00753A, Research Article
Open Access
Yupeng Cao, Xiajun Hu, Qiang Zhang, Wenda Hua, Nan Hu, Yifeng Nie, Xue Xu, Yonggang Xu, Chongqing Yang, Xiaohan Zhou, Wentao Liu, Dong Han
CW invasion by the primary tumor was inhibited by ISI of an LM. DCs were activated by the LM to sustain CR.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Fake: Amit Shah doesn't have ‘bone cancer’

A tweet attributed to Home Minister Amit Shah’s verified Twitter handle, in which he says that he has bone cancer is being circulated across social media platforms. In the tweet, Shah can be seen imploring Muslims to pray for his good health during Ramzan.




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33-year-old Olympic medal winner dies from cancer




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CVC Capital set to buy into Cancer chain HCG, to be co-promoter

Singapore's Temasek holds a 9.4% stake in the widely held company, while Indgrowth Capital owns 1.2%. Public shareholding is 76.1%, as per latest regulatory disclosures.




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Zydus Cadila launches generic prostate cancer drug at nearly 70% less price in India

"Our aim is to make a preferred choice of therapy like Obynx available and more accessible to people suffering from cancer. Bridging these unmet gaps comes from our patient-first approach," Zydus Cadila MD Sharvil Patel told .