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A metabologenomics strategy for rapid discovery of polyketides derived from modular polyketide synthases

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC04174G, Edge Article
Open Access
Run-Zhou Liu, Zhihan Zhang, Min Li, Lihan Zhang
A metabologenomics workflow using mass defect filtering (MDF) and bioinformatics-based structural prediction was established for rapid screening of modular polyketide natural products, and led to the identification of 22 polyketides.
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A polymer deposition-mediated surface-charge reformation strategy: reversing the MOF biomineralization behavior

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC05935B, Edge Article
Open Access
Yanbin Xu, Huangsheng Yang, Anlian Huang, Linjing Tong, Wei Huang, Guosheng Chen, Wei Yi, Siming Huang, Gangfeng Ouyang
A biocompatible polymer deposition-mediated surface-charge reformation strategy is reported that enables the in-place MOF biomineralization onto different enzyme templates.
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Noncentrosymmetric tellurite halides created by a depolymerization strategy: toward strong SHG intensity and wide bandgap

Chem. Sci., 2024, Advance Article
DOI: 10.1039/D4SC06403H, Edge Article
Open Access
Dan-Dan Zhou, Chun-Li Hu, Xin-Wei Zhang, Jiang-Gao Mao, Fang Kong
Successful synthesis of centrosymmetric Ga(Te3O7)Br and non-centrosymmetric M2(OH)(TeO3)(Te2O5)X (M = Al, Ga; X = Br, Cl) using a depolymerization strategy.
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In debt funds, the focus is on high-quality credit strategies: Rahul Goswami, CIO-India Fixed Income, Franklin Templeton Mutual Fund

Rahul Goswami, CIO &MD - India Fixed Income, Franklin Templeton Asset Management, on what investors can expect on the debt side from the AMC and on his rate cut expectations




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Man accused in 25 cases arrested for attempted theft at magistrate’s house in Ernakulam




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Health Ministry directs FSSAI to waive off registration fee for street food vendors

Union Health Minister, Jagat Prakash Nadda also stressed on providing ‘Street Safe’ Rapid Testing Kit to ensure safe food is used by street food vendors and highlighted the need to empower them by enrolling them on food delivery platforms




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NFRA-ICAI tussle over key audit standard overhaul: CA Institute Council to meet on Sep 17 to discuss future strategy

ICAI to debate NFRA’s plan to overhaul audit standard SA600, fearing concentration of market in few hands




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India’s new biodiversity strategy aims to protect 30% of ecosystems, restore degraded habitats by 2030

This plan aligns with the global targets set by the Kunming-Montreal Global Biodiversity Framework.




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Shamshabad diocese gets new administrator




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Trump rules out former Cabinet members Mike Pompeo, Nikki Haley in his administration

Pompeo served as the CIA Director and Secretary of State in his first term, Haley served as his ambassador to the United Nations in the first two years of Trump’s presidency




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Response strategies and biological applications of organic fluorescent thermometry: cell- and mitochondrion-level detection

Anal. Methods, 2024, 16,1968-1984
DOI: 10.1039/D4AY00117F, Minireview
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Shuai Li, Yaoxuan Li, Shiji Zhang, Haixiao Fang, Ze Huang, Duoteng Zhang, Aixiang Ding, Kajsa Uvdal, Zhangjun Hu, Kai Huang, Lin Li
In this review, we primarily summarized four temperature-response strategies. Then, we further analyzed the chemical modifications and biological applications of the probes. Finally, we have provided a prospective on the future development of probes.
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High performance and recyclable Ag/ZnO/PM substrate for the detection of organic pollutants

Anal. Methods, 2024, 16,2051-2062
DOI: 10.1039/D4AY00103F, Paper
Yixin Shao, Hongxin Cai, Lingling Yan, Hang Yu, Qiang Hu, Liang Chen, Haitao Zong, Xiufang Hou
A sensitive and recyclable substrate was fabricated through in situ reduction of silver nanoparticles on zinc oxide nanorods.
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Direct detection of dithiocarbamate fungicides by SALDI/MS using porous TiC ceramic powder as a substrate

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY01533E, Paper
Hiroshi Moriwaki, Issey Osaka, Kotaro Hashimoto, Osamu Yamada
Direct detection of dithiocarbamate fungicides (DTCs) has been achieved by SALDI/MS using porous titanium carbide (TiC) ceramic powder as a substrate.
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Establishing a new methodology for determining the water absorbability of cellulose-derived materials via a vapor-monitoring headspace strategy

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D3AY02209A, Communication
Yi-Xian Gong, Wei-Qi Xie
In this research, for the first time, we introduce a vapor-monitoring headspace strategy to establish a new methodology for determining the water absorbability of cellulose-derived materials.
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Converging optical and electrochemical detection strategies for multimodal hydrazine sensing: insights into substituent-driven diverse response

Anal. Methods, 2024, Advance Article
DOI: 10.1039/D4AY00063C, Paper
Rikitha S. Fernandes, Sahil Deepak Vasistha, Ritesh Kumar Singh, Sanket Goel, Nilanjan Dey
A pair of pyrene-based chalcogen derivatives have been developed, which demonstrate multimodal ratiometric response towards hydrazine.
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Phenylboronic acid modification-based novel dumbbell-shaped Au–Ag nanorod SERS substrates for ultrasensitive detection of SO42−

Anal. Methods, 2024, 16,2311-2321
DOI: 10.1039/D3AY01831H, Paper
Kang Shen, Caili Bi, Haifan Yang, Miaowen Xu, Lili Huang, Youwei Wang
Based on the coordination principle of Lewis acids, a novel 4-MPBA-modified dumbbell-shaped Au–Ag nanorod (4-MPBA@DS Au–AgNR) SERS substrate was developed to realize the high sensitivity and specificity of SO42− detection.
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Pathogenesis of Alzheimer's disease and therapeutic strategies involving traditional Chinese medicine

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00660G, Review Article
Shutang Li, Jinfei Yang
As research on AD has progressed, TCM and its active ingredients have increasingly played a crucial role in clinical treatment. This article summarizes extracts from TCM and briefly elucidates their pharmacological mechanisms against AD.
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Therapeutic upregulation of DNA repair pathways: strategies and small molecule activators

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00673A, Review Article
Juhyung Song, Cheoljun Park, Francis E. B. Cabanting, Yong Woong Jun
Potential therapeutic target proteins for upregulating DNA repair system are reviewed, along with reported small-molecule activators.
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Adjuvant strategies to tackle mcr-mediated polymyxin resistance

RSC Med. Chem., 2024, Advance Article
DOI: 10.1039/D4MD00654B, Review Article
Madison R. Nuske, Junlang Zhong, Renjie Huang, Vijayalekshmi Sarojini, Jack L. Y. Chen, Christopher J. Squire, Mark A. T. Blaskovich, Ivanhoe K. H. Leung
The emergence of the mobile colistin resistance (mcr) gene is a significant threat contributing to the worldwide antibiotic resistance crisis. This review discusses adjuvant strategies to restore polymyxin sensitivity in these resistant bacteria.
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Strategies for an enduring legacy

How firms can thrive in an era of social tension, economic nationalism and tech revolution




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CSIR-IICT demonstrates tech to turn dry leaves into soil conditioner

Using a method called accelerated anaerobic composting, a demonstration plant installed in a gated community in Hyderabad is turning dry leaves into bio-manure with recommended nitrogen and carbon content




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Nilgiris district administration urges people living downstream of Emerald Dam to take adequate safety measures

The Nilgiris district administration said that owing to work on the new Kundah hydro power house in Kattukuppai, water stored in the Emerald Dam will be released




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Liquid crystalline collagen assemblies as substrates for directed alignment of human Schwann cells

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00534A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Homa Ghaiedi, Luis Carlos Pinzon Herrera, Saja Alshafeay, Leonard Harris, Jorge Almodovar, Karthik Nayani
Collagen is a key component of the extracellular matrix (ECM) and well-oriented domains of collagen are important for mimicking the local cell environment in vitro. Here, we demonstrate macroscopic alignment on collagen in 2-D substrates and 3-D hydrogels.
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Aging iridium oxide catalyst inks: a formulation strategy to enhance ink processability for polymer electrolyte membrane water electrolyzers

Soft Matter, 2024, Advance Article
DOI: 10.1039/D4SM00987H, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Sunilkumar Khandavalli, Jae Hyung Park, Robin Rice, Diana Y. Zhang, Sarah A. Berlinger, Guido Bender, Deborah J. Myers, Michael Ulsh, Scott A. Mauger
Steady-shear rheology showing evolution of the microstructure of iridium oxide catalyst inks of PEM water electrolyzers with aging time.
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Solvent-Free Confinement of Ordered Microparticle Monolayers: Effect of Host Substrate and Pattern Symmetry

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM01196A, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Ignaas Jimidar, Mitch de Waard, Gijs Roozendaal, Kai Sotthewes
The self-organisation of individual suspended colloids into ordered structures that can be mediated by confinement has garnered interest recently. Despite the push for solvent reduction for sustainability reasons, the comprehension...
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Effects of Hydration Water on Bioresponsiveness of Polymer Interfaces Revealed by Analysis of Linear and Cyclic Polymer–Grafted Substrates

Soft Matter, 2024, Accepted Manuscript
DOI: 10.1039/D4SM00977K, Paper
Open Access
Shin-nosuke Nishimura, Naoya Kurahashi, Shohei Shiomoto, Yoshihisa Harada, Masaru Tanaka
Given that the hydration water of polymer matrices may differ from that of outermost polymer surfaces, processes at biomaterial–biofluid interfaces and role of hydration water therein cannot be adequately examined...
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Editorial. Solar strategies

Latest investment plans are a long-term bet




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PNB bets big on Phygital strategy to drive 20-30% business growth

With a 10,000-branch network, MD & CEO Goel eyes significant growth opportunities to expand business and scale new heights.



  • Money & Banking

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Ensuring private sector collaborations in India’s national climate strategy

For this, the Competition Commission of India needs to focus on the interplay between competition law and sustainability




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Illustrating mathematics [electronic resource] / Diana Davis, editor.

Providence, Rhode Island : American Mathematical Society, [2020]




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CREDAI’s strategic collaboration with IIMA unveils advanced real estate leadership programme

This initiative, exclusively available to senior management of CREDAI-affiliated real estate firms across India, aims to provide strategic insights and skills essential for navigating the challenges of the rapidly evolving real estate market.




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State-of-the-art strategies for Lewis acid-catalyzed strain-release cycloadditions of bicyclo[1.1.0]butanes (BCBs)

Org. Chem. Front., 2024, Advance Article
DOI: 10.1039/D4QO01741B, Review Article
Xiang Liu, Jiawei He, Keyu Lin, Xingyue Wang, Hua Cao
This review primarily focuses on the latest developments in Lewis acid-catalyzed strain-release cycloaddition reactions of BCBs.
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Bar an equal partner in the administration of justice: Telangana HC Chief Justice Alok Aradhe

Foundation of judicial system is faith and trust of litigants; steps will be taken soon to digitally serve summons in criminal cases in order to considerably reduce delays, says Telangana High Court Chief Justice




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Assessment of optimized FRET substrates as universal corona- and picornavirus main protease substrates for screening assays

RSC Adv., 2024, 14,35438-35446
DOI: 10.1039/D4RA06573E, Paper
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Conrad Fischer, Tayla J. Van Oers, Marco J. van Belkum, Tess Lamer, Aaron Romney, Pu Chen, M. Joanne Lemieux, John C. Vederas
A short FRET peptide was identified as a universal substrate for selected coronavirus Mpros. Kinetic parameters, buffer stability and Z'-assay suggest this substrate as an excellent target for CoV-Mpro HT inhibitor screening assay development.
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Bisphenol A (BPA) toxicity assessment and insights into current remediation strategies

RSC Adv., 2024, 14,35128-35162
DOI: 10.1039/D4RA05628K, Review Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Joshua O. Ighalo, Setyo Budi Kurniawan, Banlambhabok Khongthaw, Junaidah Buhari, P. K. Chauhan, Jordana Georgin, Dison Stracke Pfingsten Franco
To mitigate the toxic effects of BPA, there is a need to utilize hybrid remediation strategies for its removal from the aqueous environment.
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Taliban administration officials to attend UN climate conference in Azerbaijan

Taliban officials have taken part in U.N.-organised meetings on Afghanistan in Doha, and Taliban ministers have attended forums in China and Central Asia in the past two years




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COP29 Climate Summit Day 2 Live: Azerbaijan is victim of ‘well-orchestrated campaign of slander and blackmail’, says President Aliyev

COP29 World Climate Action Summit Live Updates: At the COP29 climate summit in Baku, Azerbaijan, countries approved vital carbon credit quality standards essential for facilitating a U.N.-backed global carbon market aimed at funding greenhouse gas reduction projects. This early agreement marks a significant step forward, despite concerns about the upcoming U.S. administration under President-elect Donald Trump, who has indicated intentions to withdraw from the Paris Agreement. Experts suggest that the endorsement might help operationalize the market by next year, enabling countries and companies to purchase carbon credits for climate initiatives worldwide. However, while the approved standards seek to address the credibility of projects, campaigners have raised concerns about their adequacy, especially regarding human rights protections. Criticism also arose regarding the decision-making process, with some nations feeling excluded from discussions. Moving forward, negotiators aim to establish further rules to ensure the market’s integrity, which could potentially yield $250 billion annually and cut carbon emissions significantly by 2030.




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Cheluvarayaswamy accuses HDK of collecting ₹1,000 cr. from steel industries to fund elections; JD(S) terms it a strategy to divert attention from ‘excise scam’

After Prime Minister Narendra Modi accused the Congress government of collecting ₹700 crore from excise sources to fund the Maharashtra elections, it was the turn of N. Cheluvarayaswamy




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Why people smoke [electronic resource] : an innovative approach to treating tobacco dependence / Frank T. Leone and Sarah Evers-Casey ; with illustrations by Joey Leone.

Philadelphia : University of Pennsylvania Press, [2023]




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Enhanced removal efficiency of Tetradesmus obliquus for nevirapine removal via co-substrate supplementation: removal mechanisms, relative gene expression and metabolomics

Environ. Sci.: Water Res. Technol., 2024, Advance Article
DOI: 10.1039/D4EW00576G, Paper
Karen Reddy, Nirmal Renuka, Muneer Ahmad Malla, Brenda Moodley, Faizal Bux, Sheena Kumari
The bioremediation of pharmaceutical wastewater by microalgae has gained scientific attention due to its cost-effectiveness and environmental friendliness.
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Investigating water quality and preservation strategies in Abuja's distribution system: a Nigerian case study

Environ. Sci.: Water Res. Technol., 2024, 10,2869-2881
DOI: 10.1039/D4EW00613E, Paper
Begmyrat Kulmedov, Lucy Achobe Akaiku, Onyebuchi Nwabueze Mogbo
The study explores how treated water quality degrades during distribution due to pipe material release and biofilm formation, with a focus on intermittent supply systems and the decreasing effectiveness of disinfectants.
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Sludge-derived novel Fe3O4–MgO@C composites for tetracycline abatement from wastewater using sustainable bio-electro-Fenton and nutrient recovery with co-precipitation: a waste-to-resource strategy

Environ. Sci.: Water Res. Technol., 2024, Advance Article
DOI: 10.1039/D4EW00684D, Paper
Azhan Ahmad, Monali Priyadarshini, Shraddha Yadav, Makarand M. Ghangrekar, Rao Y. Surampalli
Developing efficient Fenton catalysts for the remediation of emerging pollutants is one of the challenges for researchers.
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Vedanta plans to invest $500 million in group firm AvanStrate Inc.

“This investment is aimed at driving innovation and expansion within ASI, strengthening its focus on R&D,” the company said




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Centre for Development Studies: Looking to the future, evolving strategies to meet present-day challenges

CDS is evolving strategies for research and financial self-sufficiency while maintaining original mandate, exploring new programmes and training opportunities.




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Leadership void at DUK and KTU: Administrative challenges persist amid Vice-Chancellor vacancies




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‘Players, administrators should debate future of cricket’

Sri Lankan legend Kumar Sangakkara also believes T20 can spread cricket to unfamiliar territories




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U.K. govt. doesn’t have a Brexit strategy: Document




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Contenders for key jobs in Trump administration

A senior Trump official said the job of national security adviser has been offered to retired Lieutenant General Michael Flynn.




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NEET UG 2024 counselling registration to begin on August 14, confirms NMC Secretary

Additionally, the NEET UG 2024 results were revised, resulting in a decline in the number of toppers.




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An innovative CuxAg50−x/UiO66-NH2 photocatalyst prepared using a dual ship bottling strategy for photocatalytic CO2 reduction: controlled product selectivity and pathways

Energy Environ. Sci., 2024, 17,8228-8242
DOI: 10.1039/D4EE03103B, Paper
Lipeng Jiang, Dengqian Chen, Zhengkai Hao, Dongxue Cao, Runqiao Liu, Jingyu Cheng, Limei Chen, Xin Liu, Boyin Jia, Dongdong Liu
This study proposed a “dual ship bottling” strategy to synthesize CuxAg50−x/UiO66-NH2, achieving over 90% selectivity for reduced carbon products.
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