Drummers hear all the jokes. What do you call a drummer with half a brain? Gifted. How is a drum solo like a sneeze? You know it's coming, but there's nothing you can do about it. What do you call a drummer that breaks up with his girlfriend? Homeless.

Drummers hear the jokes — and laugh. Because they know they’re the thumping heartbeat of any band. They’re the ones with loads of equipment. And they’re the ones making all that noise while practicing. Yet try to play almost any song without drums and the lack of propulsion and power is instantly palpable.

Drummers are essential. Now, users can join their ranks — and they don’t even need to buy a massive drum kit or rattle their walls to do it. Created by drummers, Senstroke by Redison is the first sensor device that can teach anyone to play the drums and even reproduce the drummer experience, all without any physical drum set.

Just attach the patented Senstroke sensors to a pair of drumsticks and your feet, connect via Bluetooth, and instantly you can turn any surface into a virtual drumhead. Using the impact of the drumsticks and your feet positioning, the sensors reproduce the exact sounds your chosen drum element would make through the Senstroke app. 

Your legs, some cushions, a coffee table, they all become fair game as a drum surface while you refine your skills. And when you attach a pair of headphones, no one else even has to know you’re playing...well, Read the rest

A couple weeks ago, my pals at Twitter were kind enough to invite me in to visit with their (rapidly growing) team. The topic was meetings, so I used it as an opportunity to publicly premiere a talk I've been presenting to private clients over the past few months.

I hope you'll enjoy, Broken Meetings (and how you'll fix them).

Slides:

Supplementary links and commentary forthcoming, but I wanted to go ahead and post the talk as quickly as the video was available. Special thanks to Michelle, Jeremy, and the crackerjack Twitter crew for a swell afternoon.

I really like this talk and sincerely hope you will find it useful in helping to un-break your own meetings.

The DML News App offers the best in news reporting.

The post BREAKING: Founding Father of Rock Who Broke Musical Barriers, Dead at 87 appeared first on Dennis Michael Lynch.

4 September 2019 , Volume 95, Number 5

• Review of Chan Wook Park's Stoker.
• What We Watched: Dredd, The Artist is Present, Side by Side, Silver Lining's Playbook, Arrested Development, All-Star Celebrity Apprentice, Bob's Burgers.

Ricardo G. Durán, Enrique Otárola and Abner J. Salgado
Math. Comp. 89 (2020), 1581-1603.
Abstract, references and article information

Guher Camliyurt, Igor Kukavica and Vlad Vicol
Trans. Amer. Math. Soc. 373 (2020), 3375-3422.
Abstract, references and article information

D. Pauly and S. Repin
St. Petersburg Math. J. 31 (2020), 533-555.
Abstract, references and article information

Stretching from Sai Kung on the east coast to Tuen Mun in the west, the whopping 100 km-long MacLehose Trail is the longest and first long-distance hiking trail in Hong Kong.

The trail is divided into 10 sections and traverses eight country parks which embrace magnificent natural scenery, interesting historical relics and a wide range of wild fauna and flora, winding past the coastline, rugged mountains, valleys and reservoirs to provide a diverse outdoor experience for hikers.

It was even named as one of the world's 20 dream trails by National Geographic.

A lot of hard work went into building the trail, with Agriculture, Fisheries & Conservation Department workers out in the elements without much shelter, often carrying heavy equipment uphill and downhill over varied terrain.

Building bonds

Wan Keung and Lai Hing joined the department around 40 years ago. They both took part in the MacLehose Trail project which was started in 1979 to promote hiking activities in Hong Kong.

The project was named after the then-Governor Sir Murray MacLehose - who was himself a keen walker - for his significant efforts to conserve Hong Kong’s countryside.

“I have contributed a lot to the trail. I am happy as it is packed with people now,” said Mr Wan.

While Mr Lai added: “We are going to retire, but the trail will be here for a long time.”

Despite working on the same project, the pair - now in their 60s - only met for the first time recently because they were assigned to different work stations back then. However, they became firm friends instantly.

From setting up the many signposts along the way, to hand-building the heavy stone steps, the two men eagerly shared all the skills and techniques they learnt on the project.

Listening to their conversations now it is hard to imagine that when they first started work, both had little practical knowledge about constructing a trail. They acquired welding, plastering and woodwork skills through hands-on experience and with the support of their seniors. But that was not the biggest challenge they encountered.

“Building the trail was really difficult, as there were so many sections. We were either drowned in sweat or drenched by rain while working,” Mr Lai explained.

One poignant memory for Mr Wan was of working during wildfires that raged through the countryside.

“There was only one thing for it: we stayed until the fire was extinguished. That was really hard.”

Lasting legacy

After nine months’ hard work the MacLehose Trail was finally opened on October 26, 1979.

These days Mr Wan and Mr Lai enjoy the trail for leisure instead of work.

Both said receiving compliments from family and friends or witnessing the sheer enjoyment of hikers on the trail made their hard work worthwhile.

They now hope to pass on their skills to the younger workers, so that a new generation of Hong Kong people can take care of the trail and ensure it lasts for decades to come.

Members Event Screening Room

Event participants

Nigol Bezjian, Director, Broken Dinners, Postponed Kisses
Chair: Rima Maktabi, Bureau Chief, Al Arabiya (UK)

In Matt Egan's absence first time host Henry Burrell heroically steps in to chat about Pokemon Go with producer Chris. Then fellow staff writer Chris Minasians discusses iOS 10 beta and all of the rumoured features for the latest Apple operating system, including dark mode (10:30). Finally, Lewis Painter, staff writer at PC Advisor, talks about Playstation VR being released for the PS4, pricing and games (23:30).  

See acast.com/privacy for privacy and opt-out information.

For the second week running hosting duties are taken by Henry Burrell, who is joined by Techworld.com editor Charlotte Jee to discuss the impact of Brexit on the UK's startups. Producer Chris then jumps in to discuss the Pokemon Go launch in the UK and a debate breaks out over whether it is for adults (13:00) Finally, online editor at Computerworld UK Scott Carey brings the latest news around driverless cars, from Tesla's recent struggles and how it may affect the industry in general (25:00)  

See acast.com/privacy for privacy and opt-out information.

Endorepellin, the C-terminal fragment of the heparan sulfate proteoglycan perlecan, influences various signaling pathways in endothelial cells by binding to VEGFR2. In this study, we discovered that soluble endorepellin activates the canonical stress signaling pathway consisting of PERK, eIF2α, ATF4, and GADD45α. Specifically, endorepellin evoked transient activation of VEGFR2, which, in turn, phosphorylated PERK at Thr980. Subsequently, PERK phosphorylated eIF2α at Ser51, upregulating its downstream effector proteins ATF4 and GADD45α. RNAi-mediated knockdown of PERK or eIF2α abrogated the endorepellin-mediated up-regulation of GADD45α, the ultimate effector protein of this stress signaling cascade. To functionally validate these findings, we utilized an ex vivo model of angiogenesis. Exposure of the aortic rings embedded in 3D fibrillar collagen to recombinant endorepellin for 2–4 h activated PERK and induced GADD45α vis à vis vehicle-treated counterparts. Similar effects were obtained with the established cellular stress inducer tunicamycin. Notably, chronic exposure of aortic rings to endorepellin for 7–9 days markedly suppressed vessel sprouting, an angiostatic effect that was rescued by blocking PERK kinase activity. Our findings unravel a mechanism by which an extracellular matrix protein evokes stress signaling in endothelial cells, which leads to angiostasis.

Mandeep Bajaj
Dec 1, 2012; 61:3078-3080
Commentary

  Don’t make fun of the flower arranger, Ikebana Is self – discipline, a Nip here, a Snip there, and With fullness of time, and Passage through life, Done with the flash of a scissor, Bone handles, Glinting, Scissor flash snip, all gone Extra weight, things un-needed, flash Unheeded, If you stop, To think about, […]

It’s not news that the current fight against COVID-19 has overshadowed plans of artistes worldwide, having impacted some of their biggest stages and platforms with the cancellation of not only large-scale events but private ones as well. Birthday...

In the US the licence, or marketing authorisation, for alteplase is limited to 0-3 hours after onset of stroke, but some other countries - including the UK and Australia - have extended the licence to 4.5 hours. In an analysis article on thebmj.com Brian Alper, vice president of evidence based medicine research and development at Dynamed, and...

Cardiovascular factors are associated with risk of stroke - and those factors can be mediated by lifestyle and by genetic make up. New research published by The BMJ sets out to explore how these risks combine, and we're joined on the podcast by two of the authors - Loes Rutten-Jacobs, senior postdoctoral researcher at the German Center for...

Stroke mortality rates have been declining in almost every country, and that reduction could result from a decline in disease occurrence or a decline in case fatality, or both. Broadly - is that decline down to better treatment or better prevention. Olena Seminog, a researcher, and and Mike Rayner, professor of population health, both from the...

27 June 2017

Policymakers must take action immediately to mitigate the risk of severe disruption at certain ports, maritime straits, and inland transport routes, which could have devastating knock-on effects for global food security.

• Trade chokepoints – maritime, coastal and inland – pose an underexplored and growing risk to global food security.
• Maritime chokepoints will become increasingly integral to meeting global food supply as population growth, shifting dietary preferences, bioenergy expansion and slowing improvements in crop yields drive up demand for imported grain.
• Rising trade volumes, increasing dependence on imports among food-deficit countries, underinvestment, weak governance, climate change and emerging disruptive hazards together make chokepoint disruptions – both small-scale and large-scale – increasingly likely.
• Climate change will have a compounding effect on chokepoint risk, increasing the probability of both isolated and multiple concurrent weather-induced disturbances.
• Investment in infrastructure lags demand growth: critical networks in major crop-producing regions are weak and ageing, and extra capacity is urgently needed. 

The Las Vegas Raiders have agreed to a deal with free agent running back Devontae Booker.

The deadline for abstracts for the upcoming National Summit on Smokeless Tobacco Prevention is Feb. 29.

Televangelist Jim Bakker is recovering at his North Carolina home after having a stroke, his wife said Friday.

Rapper YoungBoy Never Broke Again's "38 Baby 2" is No. 1 on the U.S. album chart.

If this were Britain, Russia or India, Rudy Giuliani '08 caps would not be on the clearance racks. In those countries, where bigwigs and insiders get to nominate party leaders, the former Republican front-runner and establishment favorite would have long ago been anointed the winner.

This recipe was featured on Foodie Tuesday, a weekly segment with Raf Epstein on Drive, 774 ABC Melbourne, 3:30 PM, courtesy of Neil Perry. Neil's new book is "Spice Temple."

This recipe was featured on Foodie Tuesday, a weekly segment with Raf Epstein on Drive, 774 ABC Melbourne, 3:30 PM, courtesy of Neil Perry. Neil's new book is "Spice Temple."

Once you've peeled and cored the quinces there's really little work to do to make this gorgeous dessert. They just bubble away happily for a few hours while the sugar and long slow cooking cast their spell, transforming the quinces' hard, ivory-coloured flesh until it's meltingly soft and an incredible deep-rose colour.

This recipe features on Foodie Tuesday, a weekly segment on 774 Drive with Raf Epstein, 3.30PM, courtesy of Justine Schofield. Justine's latest book is "Dinner With Justine".

Delicious Australian dish with fresh Lilly Pilly and finger lime spritzer.

This recipe features on Foodie Tuesday, a weekly segment on 774 Drive with Raf Epstein, 3.30PM, shared by Dan Hunter, chef and owner of Otways' restaurant Brae.

200 gm flaked salt 200 gm brown sugar 1 side ocean trout, skin on, pinboned 1/2 cup smoking shavings/sawdust Salad 1 butter lettuce 1 baby endive lettuce 2 Lebanese cucumbers 200 ml creme fraiche 100 ml vinaigrette (25 ml sherry vinegar, 25 ml olive oil, 50 ml grape seed oil) Salt and pepper 2 Granny Smith apples 1 stick celery Bunch chives

NBA legend and recreational gambler Charles Barkley is presented with the following hypothetical on ESPN radio: You are winning big at the poker table when a beautiful woman sits down next to you. “Do you stay with the hands or do you leave?” Barkley: “Bro, gambling is so fickle, I love to gamble, when you [...]

By some estimates, work-related stress drains the US economy of nearly 300 billion dollars a year -- and it can hurt your productivity and personal health too, says wellness advocate Rob Cooke. He shares some strategies to help put your mental, physical and emotional well-being back at the forefront.

By Emily Reynolds. Study finds viewers had slightly more negative perceptions of people with mental illness after seeing the movie.

The Christie administration is arguing that the only way to improve education in the state's poorest districts is to ditch teacher job protections.

Cooking, Australian.

Pokémon Go (Game) -- Social aspects.