Afghan President Ashraf Ghani has ordered a probe into the drowning of several Afghan migrants last week after reports that Iranian border guards allegedly forced them into a river.

Federal investigators have found "reasonable grounds" that a government whistleblower was punished for speaking out against widespread use of an unproven drug that President Donald Trump touted as a remedy for COVID-19, his lawyers said.

The Chinese Ministry of Commerce (“MOFCOM”) recently announced the intention of the Chinese competition authorities to step up the number of their investigations into possible anti-competitive and abusive market conduct.  Chinese co...

Competition Law E-Briefing: Fashion sector competition probe On Tuesday 24 March 2015, the UK’s competition regulator, the Competition and Markets Authority (the “CMA”), opened an investigation into suspected anti-competitive arrangements in the UK ...

The Hong Kong Court has recently confirmed the Securities and Futures Commission (“SFC”)’s powers to seize, search and compel access to digital devices rejecting challenges to such powers based on privacy grounds. Data privacy is a...

We have begun an independent investigationinto the contact the Metropolitan Police Service (MPS) had with a man before he suffered a life-changing injury in Haringey, north London on Monday 4 May 2020. The MPS made a mandatory referralto us following the incident when police on patrol approached a man, in his 20s, on Burgoyne Road, N4. Such a referralis usual practice when a person is seriously injured following direct or indirect police contact. We understand that the man ran off and police officers chased and then Tasered him as he jumped over a wall. The man fell and suffered serious injuries. He was arrested for drug related offences and was taken to hospital where he was assessed as...

On Thursday, 7 May, the IOPC launched an independent investigation into the full circumstances of an incident in Haringey on 4 May in which a man sustained serious injuries. We fully support this investigation and continue to co-operate with the IOPC's...

From resounding applause to ostracisation and isolation.That is essentially...

Arti Zodpe is from the Tamasha (folk dance-drama) theatre in Sangli, in India’s Maharashtra state. After evening performances, some of the singers and dancers offer sex work services to the audience. “We [Tamasha sex workers] live outside of the city as people feel disturbed by the sound of our ghunghroo [anklet bracelets with bells] and […]

The post India’s Liberal Abortion Law, Nullified by Social Stigma appeared first on Inter Press Service.

The Environmental Audit Committee (“EAC”) has launched an inquiry to investigate the impact of toxic chemicals on everyday life (launched 12 February 2019). The inquiry will focus on the use of toxic chemicals in everyday products includ...

Sports stars sign letter sent to U.S. Attorney General Bill Barr and FBI Director Christopher Wray

[Dalsan Radio] The African Union Mission in Somalia, AMISOM, expresses its heartfelt condolences to the families of those who perished in the plane crash of 4th May, 2020. The aircraft which left Baidoa, had six people on board and was approaching Bardale, south of Somalia and 300km northwest of the capital Mogadishu when it crashed.

[Shabelle] The African Union and the UN have welcomed the decision by leaders from Somalia, Kenya, and Ethiopia to investigate Monday's plane crash in southwest Somalia which killed six people on board.

China says it supports World Health Organisation efforts to investigate the origin of the Covid-19 pandemic, but rejects any “presumption of guilt”, after the global body said it was talking to Beijing about sending another delegation to the country.The remarks came as Beijing is under mounting international pressure – particularly from the United States – to allow an inquiry into how the pandemic started, and if it was linked to a laboratory in Wuhan, the city where the new virus strain was…

From resounding applause to ostracisation and isolation.That is essentially the journey Lt. Cmdr. Robert Embleton, who served 34 years in Britain’s Royal Navy, took by ambulance when discharged from Derriford Hospital in Plymouth, southwestern England, on April 8 following his near-month sickness with Covid-19.Arriving at his retirement home, he immediately went into self-isolation with his wife of 55 years, Jean, who has shown no symptoms of the virus. Soon after, Embleton realised he was…

'Australia is “gum stuck to the bottom of China’s shoe”, huh? Ok, well, it’s time for Australia to rethink trade and other agreements with China if they don’t like criticism'

STAMFORD, CT - HARMAN, the premium global audio and infotainment group (NYSE:HAR), has been awarded two Plus X Awards in the categories Innovation and High Quality for their ground-breaking sound solutions QuantumLogic Surround 3D and Clari-Fi. In addition, Clari-Fi also received the Plus X Award for “Best Audio Software of the Year”. The awards have been presented earlier today at the German Bundestag in Bonn. The Plus X Award honors manufacturers for new and innovative technologies, extraordinary design and intelligent and easy to use operating systems. With an international and independent panel of judges from 25 industries, the Plus X Award is the world’s largest competition for technology, sports and lifestyle.

NFL greats Tom Brady and Anquan Boldin were among dozens of prominent players and coaches who called on Friday for a federal investigation into the death of Ahmaud Arbery, an unarmed black man who was shot while running in Georgia.

Title: Mentally Ill Kids Face Widespread Stigma
Category: Health News
Created: 5/1/2007 2:00:00 AM
Last Editorial Review: 5/1/2007 12:00:00 AM

Title: Overweight Teens Feel Stigmatized, Bullied: Study
Category: Health News
Created: 5/1/2014 9:35:00 AM
Last Editorial Review: 5/1/2014 12:00:00 AM

Title: VA Clinic Investigating Unsanitary Treatment Room
Category: Health News
Created: 5/1/2018 12:00:00 AM
Last Editorial Review: 5/1/2018 12:00:00 AM

APHA member Elena Ong, PHN, MS, past president and founding CEO of the Asian & Pacific Islander Caucus for Public Health, a recent APHA Executive Board member, and a past vice president of the Southern California Public Health Association, discusses discrimination against Asians in the U.S. and beyond.

South Africa is a mineral-rich country with a diverse geology and a long history of mining. The rich history of mining activities includes the extraction of coal from the Ecca Group Sediments of the Karoo Supergroup (250 Ma), gold and uranium from the Witwatersrand Supergroup (2900 Ma), as well as platinum, uranium, tin and lead from the layered Bushveld Igneous Complex (BIC) (2150 Ma). The extraction of gold, copper, tin, lead and rare earth minerals also took place in the Archean rocks of Swazium age (3500–3000 Ma). The historical mining records have either not been accurately recorded or have been lost over time. This has resulted in significant geohazard risk during infrastructure development, especially in and around historical mining towns, such as Johannesburg and Ermelo. These geohazard risks require careful appraisal and quantification prior to any infrastructure design or construction.

This case study aims to set out the development aspects of the Multi-Faceted Geophysical Modelling Systems approach, which was used by the South African National Roads Agency SOC Ltd (SANRAL) during an investigation of undermined ground for the historical coal-mining town of Ermelo in South Africa. The N11/N2 ring road was planned to go around Ermelo to ensure mobility between major routes, whilst still maintaining town access.

The systems approach used a combination of airborne geophysics (Versatile Time Domain Electromagnetic System (VTEM^TM) and magnetics), generally used in mining exploration, land-based and borehole geophysics, borehole water testing, and ground-truthing. The approach was continuous and iterative, building on the data at hand and reducing unnecessary investigations while eliminating the possibility of anomalies being missed, as in the case of conventional discrete drilling. The investigation ensured that 100% of the route was comprehensively investigated with a high confidence in the geological and geophysical data, and concomitant mitigation of infrastructure risk.

The Multi-Faceted Geophysical Modelling Systems approach was successfully used to identify a previously unknown 1 x 1 m mining stope cavity at 90 m depth and a 3 x 5 m access tunnel at 24 m depth in a timely and cost-effective manner. Seven reverse-circulation percussion boreholes confirmed the structural integrity of these underground cavities, as well as the structural geology along the centreline. Based on the great success achieved in identifying shallow anomalies, this Multi-Faceted Geophysical Modelling Systems approach is now being considered for field trails on the dolomitic formations and the Wild Coast greenfields road project where there are large historical slumps and many fault lines.

Thematic collection: This article is part of the Ground-related risk to transportation infrastructure collection available at https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure

Klebsiella species are problematic pathogens in neonatal units and may cause outbreaks, for which the sources of transmission may be challenging to elucidate. We describe the use of whole-genome sequencing (WGS) to investigate environmental sources of transmission during an outbreak of extended-spectrum-β-lactamase (ESBL)-producing Klebsiella michiganensis colonizing neonates. Ceftriaxone-resistant Klebsiella spp. isolated from neonates (or their mothers) and the hospital environment were included. Short-read sequencing (Illumina) and long-read sequencing (MinION; Oxford Nanopore Technologies) were used to confirm species taxonomy, to identify antimicrobial resistance genes, and to determine phylogenetic relationships using single-nucleotide polymorphism profiling. A total of 21 organisms (10 patient-derived isolates and 11 environmental isolates) were sequenced. Standard laboratory methods identified the outbreak strain as an ESBL-producing Klebsiella oxytoca, but taxonomic assignment from WGS data suggested closer identity to Klebsiella michiganensis. Strains isolated from multiple detergent-dispensing bottles were either identical or closely related by single-nucleotide polymorphism comparison. Detergent bottles contaminated by K. michiganensis had been used for washing milk expression equipment. No new cases were identified once the detergent bottles were removed. Environmental reservoirs may be an important source in outbreaks of multidrug-resistant organisms. WGS, in conjunction with traditional epidemiological investigation, can be instrumental in revealing routes of transmission and guiding infection control responses.

The IR Biotyper is a new automated typing system based on Fourier-transform infrared (FT-IR) spectroscopy that gives results within 4 h. We aimed (i) to use the IR Biotyper to retrospectively analyze an outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae (ESBL-KP) in a neonatal intensive care unit and to compare results to BOX-PCR and whole-genome sequencing (WGS) results as the gold standard and (ii) to assess how the cutoff values used to define clusters affect the discriminatory power of the IR Biotyper. The sample consisted of 18 isolates from 14 patients. Specimens were analyzed in the IR Biotyper using the default analysis settings, and spectra were analyzed using OPUS 7.5 software. The software contains a feature that automatically proposes a cutoff value to define clusters; the cutoff value defines up to which distance the spectra are considered to be in the same cluster. Based on FT-IR, the outbreak represented 1 dominant clone, 1 secondary clone, and several unrelated clones. FT-IR results, using the cutoff value generated by the accompanying software after 4 replicates, were concordant with WGS for all but 1 isolate. BOX-PCR was underdiscriminatory compared to the other two methods. Using the cutoff value generated after 12 replicates, the results of FT-IR and WGS were completely concordant. The IR Biotyper can achieve the same typeability and discriminatory power as genome-based methods. However, to attain this high performance requires either previous, strain-dependent knowledge about the optimal technical parameters to be used or validation by a second method.

Editor’s Note: This article is adapted from the address Ms. Valentine delivered as the recipient of the American Diabetes Association’s (ADA’s) Outstanding Educator in Diabetes Award for 2019. She delivered the address in June 2019 at the Association’s 79th Scientific Sessions in San Francisco, CA. A webcast of this speech is available for viewing at the ADA website (professional.diabetes.org/webcast/outstanding-educator-diabetes-award-lecture%E2%80%94-most-important-thing-we-give-people-hope).

Glass is the favorite material for parenteral packaging because of its physico-chemical properties. Type I borosilicate glass is worldwide use at this scope, but it may have some issues related to breakage, corrosion and delamination that might compromise the drug quality, safety and efficacy. These issues can be mitigated and avoided starting from the appropriate selection of the most suitable raw material at the early stage of the glass container design. In this study, Type I borosilicate glass vials manufactured using two glass tubes having different chemical compositions, were studied and compared in terms of their resistance to corrosion. Testing design was applied with the aim to select the best practice approach comparing different storage simulation conditions: ageing treatment through autoclaving and stability testing (real-time and accelerated). Clear differences were found between the different glass types in terms of hydrolytic and corrosion resistance that highlighted the relation between chemical composition and glass chemical durability. Non-negligible differences were also observed using different storage conditions.

OBJECTIVE

Hispanics/Latinos are the largest ethnic/racial group in the U.S., have the highest prevalence of diabetes, and are at increased risk for neurodegenerative disorders. Currently, little is known about the relationship between diabetes and cognitive decline and disorders among diverse Hispanics/Latinos. The purpose of this study is to clarify these relationships in diverse middle-aged and older Hispanics/Latinos.

Bacterial persisters are phenotypic variants that temporarily demonstrate an extraordinary tolerance toward antibiotics. Persisters have been linked to the recalcitrance of biofilm-related infections; hence, a complete understanding of their physiology can lead to improvement of therapeutic strategies for such infections. Mechanisms pertaining to persister formation are thought to be associated with stress response pathways triggered by intra- or extracellular stress factors. Unfortunately, studies demonstrating the effects of osmolyte- and/or pH-induced stresses on bacterial persistence are largely missing. To fill this knowledge gap within the field, we studied the effects of various osmolytes and pH conditions on Escherichia coli persistence with the use of phenotype microarrays and antibiotic tolerance assays. Although we found that a number of chemicals and pH environments, including urea, sodium nitrite, and acidic pH, significantly reduced persister formation in E. coli compared to no-osmolyte/no-buffer controls, this reduction in persister levels was less pronounced in late-stationary-phase cultures. Our results further demonstrated a positive correlation between cell growth and persister formation, which challenges the general notion in the field that slow-growing cultures have more persister cells than fast-growing cultures.

Animal models of bacterial infection have been widely used to explore the in vivo activity of antibacterial drugs. These data are often submitted to the U.S. Food and Drug Administration to support human use in an investigational new drug application (IND). To better understand the range and scientific use of animal models in regulatory submissions, a database was created surveying recent pneumonia models submitted as part of IND application packages. The IND studies were compared to animal models of bacterial pneumonia published in the scientific literature over the same period of time. In this review, we analyze the key experimental design elements, such as animal species, immune status, pathogens selected, and route of administration, and study endpoints.

Screenshots showing repugnant and insulting remarks — some misogynistic, some racist, others hinting at drug use and sexual conquests — from a private group chat between several hockey players, including ...

U.S. Chief Justice John Roberts on Friday put a temporary hold on the disclosure to a Democratic-led House of Representatives committee of grand jury material redacted from former Special Counsel Robert Mueller's report on Russian interference in the 2016 election.

NFL greats Tom Brady and Anquan Boldin were among dozens of prominent players and coaches who called on Friday for a federal investigation into the death of Ahmaud Arbery, an unarmed black man who was shot while running in Georgia.

The shipment of Ebola and henipavirus samples to Wuhan has given rise to groundless conspiracy theories involving Xiangguo Qiu. But there is no evidence whatsoever tying her to COVID-19

The overhaul of campus sexual assault regulations will ramp up the paperwork schools must do to comply with Title IX.

Chief Justice John G. Roberts on Friday declined to order a judicial misconduct investigation into a federal judge's retirement and whether Senate Majority Leader Mitch McConnell had anything to do with it.

D.C. Circuit Court of Appeals Judge Sri Srinavasan had previously asked the chief justice to assign a court ...

The Dutch privacy watchdog said on Friday it would investigate how Chinese-owned social media app TikTok, which has become hugely popular during the COVID-19 pandemic, handles the data of millions of young users.

The Royal Navy is investigating reports that a nuclear submarine crew held a party after returning to their UK base while the rest of the country was under coronavirus lockdown.

Key items of protective equipment were not included in the government's pandemic stockpile when coronavirus hit the UK, an investigation has found.

Global health experts are investigating reports of a rare but serious illness affecting children and its links to coronavirus after UK medics raised the alarm.

Tower Bridge was cordoned off at around midday on Friday while police investigated reports of a "suspicious package."

A distressing video of an unidentified woman boxing her German Shepherd dog has sparked outrage on social media and prompted an investigation into alleged animal cruelty.

Lawyers say failure to provide adequate PPE may amount to corporate manslaughter

• Coronavirus – latest updates
• See all our coronavirus coverage

The deaths of more than 50 hospital and care home workers have been reported to Britain’s health and safety regulator, which is considering launching criminal investigations, the Guardian has learned.

The Health and Safety Executive (HSE), which investigates the breaking of safety at work laws, has received 54 formal reports of deaths in health and care settings “where the source of infection is recorded as Covid-19”. These are via the official reporting process, called Riddor: Reporting of Injuries, Diseases and Dangerous Occurrences.

Lethbridge police are being investigated by an outside force after handcuffing a woman in a stormtrooper costume outside a Star Wars-themed business earlier this week. But still the force faces accusations that not enough is being done to investigate what happened.

Police have dropped an investigation into two prominent Brexit campaigners accused of breaching spending rules during the referendum campaign. In 2018 the Electoral commission said that Alan Halsall, of Vote Leave, and Darren Grimes, founder of pro-Brexit youth group BeLeave, failed to declare a payment related to the campaign. The watchdog said that BeLeave "spent more than £675,000 with (Canadian data firm) Aggregate IQ under a common plan with Vote Leave". This spending took Vote Leave over its £7 million legal spending limit by almost £500,000. Vote Leave paid a £61,000 fine, but denied wrongdoing, while Mr Grimes won an appeal against his £20,000 fine in July. The Commission also referred the pair to the Metropolitan Police but on Friday it was revealed that the investigations had now been dropped. A spokesman for the Leave campaigners said: "The Metropolitan Police has written to Vote Leave board member Alan Halsall and BeLeave founder Darren Grimes to confirm that it will not be acting on allegations made against them by the Electoral Commission and various Remain campaigners. "This marks the end of a two-year ordeal for both individuals." Mr Grimes, 26, said the development called into question whether the Electoral Commission was "fit for purpose". He had insisted since the allegations were first made that he was "completely innocent" of making false declarations in relation to the £680,000 donation. In a statement, Mr Grimes, a former fashion student originally from County Durham, said: "The Metropolitan Police has found, after investigation and consultation with the Crown Prosecution Service, that there is no case to be answered. "Once again the Electoral Commission has been found to be part of the mob, a quango out of control that isn't policing elections so much as punishing Leavers who have the temerity to win them. "My ordeal at the hands of the kangaroo court that is the Electoral Commission is now over, but questions must now be asked of whether that body is fit for purpose." Mr Halsall, the responsible person for Vote Leave, said he was "delighted to have been exonerated" and thanked the police for their "professional" investigation. "I was very disappointed that my colleagues at Vote Leave and myself were never given the opportunity of making our case in person to the Electoral Commission before being fined and reported to the police," he added. "It seems a rather unusual way of conducting an inquiry into such matters that only the so-called whistleblowers who made these allegations are interviewed by the regulator." A spokesman for the Met said an investigation into the Electoral Commission's allegations against Vote Leave and BeLeave, submitted on July 17 2018, was handed over in October to the Crown Prosecution Service (CPS). "On Tuesday, March 3 preliminary advice was received from the CPS," said the force spokesman. "This advice has now been duly considered and no further action will be taken."

Federal investigators have found “reasonable grounds” that a government whistleblower was punished for speaking out against widespread use of an unproven drug that President Donald Trump touted as a remedy for COVID-19, his lawyers said. Dr. Rick Bright headed the Biomedical Advanced Research and Development Authority, a unit of Department of Health and Human Services that focuses on countermeasures to infectious diseases and bioterrorism. The OSC is an agency that investigates allegations of egregious personnel practices in government.

Police have no suspects in connection with the fires.