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Fed Chair Powell says U.S. economy is in 'solid shape' with more rate cuts coming




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Can India escape middle-income trap?

How does the World Bank define the threshold for middle-income economies? Why is state intervention considered crucial for breaking the middle-income trap? What lessons can be drawn from South Korea and Chile? What challenges does India face in balancing state intervention with democratic values?




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Extent of leak, key to ordering NEET-UG re-test: Apex court

Supreme Court considers cancellation of NEET-UG 2024 due to leaked questions affecting 23 lakh students, seeks extent of leak.




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Antier’s EduBlock Pro uses blockchain to prevent exam paper leaks

India’s exam integrity crisis tackled with blockchain innovation




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Bengaluru Comic Con: Meet the creators of War and Peas, Brown Paperbag Comics, Bakarmax and more

The creators of War and Peas, Brown Paperbag Comics, Bakarmax and more talk about the growth of the Indian webcomics scene as the stage is set for Bengaluru Comic Con




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Captivating ink and paper

A physical book provides a sensory experience that is way better than that of the electronic version




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Giving shape to India’s carbon credit mechanism

India’s carbon credit mechanism needs to be aligned with international and domestic realities if it is to be effective




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Human Milk Metals and Metalloids Shape Infant Microbiota

Food Funct., 2024, Accepted Manuscript
DOI: 10.1039/D4FO01929F, Paper
Open Access
Eduard Flores Ventura, Manuel Bernabeu, Belén Callejón Leblic, Raúl Cabrera-Rubio, Laxmi Yeruva, Javier Estañ-Capell, Cecilia Martínez-Costa, Tamara García-Barrera, Maria Carmen Collado
Background: The profile of metal (loid)s in human milk is essential for infant growth and development, yet its impact on the development of the infant microbiota remains unclear. Elements such...
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A well-woven tapestry

‘Maniyosai’ recounted Palghat Mani Iyer’s musical journey. Suganthy Krishnamachari writes




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Reducing meso-lactide formation from racemic lactic acid using shape-selective H-Beta zeolite

Catal. Sci. Technol., 2024, 14,6331-6337
DOI: 10.1039/D4CY01046A, Paper
Ling Ding, Lou Gao, Di Pan, Ke Du, Jiayu Yu, Wanyi Li, Yahong Zhang, Yi Tang
Efficiently reduce the formation of meso-lactide from racemic lactic acid by utilizing H-Beta zeolite shape selectivity towards lactic acid dimers.
The content of this RSS Feed (c) The Royal Society of Chemistry




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DON encapsulated carbon dot–vesicle conjugate in therapeutic intervention of lung adenocarcinoma by dual targeting of CD44 and SLC1A5

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR00426D, Paper
Afreen Zaman, Aparajita Ghosh, Anup Kumar Ghosh, Prasanta Kumar Das
HACD–TMAV, a carbon dot–vesicle conjugate, selectively delivered glutamine inhibitor DON to CD44-enriched cancer cells, inducing ROS triggered apoptosis by dual targeting CD44 and SLC1A5 through downregulation of PI3K/AKT/mTOR signalling cascade.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Nanoparticle’s shape is the game-changer for blood-brain barrier crossing and delivering through tunneling nanotubes among glioblastoma cells.

Nanoscale, 2024, Accepted Manuscript
DOI: 10.1039/D4NR03174A, Paper
Open Access
Giulia Sierri, Ines Saenz-de-Santa-Maria, Antonio Renda, Marcus Koch, Patrizia Sommi, Umberto Anselmi-Tamburini, Mario Mauri, Alessia D'Aloia, Michela Ceriani, Domenico Salerno, FRANCESCO MANTEGAZZA, Chiara Zurzolo, Francesca Re
Tunneling Nanotubes (TNTs) are thin, dynamic, long membrane protrusions that allow the intercellular exchanges of signal clues, molecules and organelles. The presence of TNTs and their involvement as drug delivery...
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Shape-controlled, water-assisted synthesis of 2D luminescent CsPb2Br5 perovskite microcrystals for highly responsive UV detectors

Nanoscale, 2024, Advance Article
DOI: 10.1039/D4NR03021D, Paper
Dipayan Ray, Ankush Saini, Ankit Kumar, Sumit Kumar, Monojit Bag, Prasenjit Kar
Water-assisted, growth-controlled synthesis of CsPb2Br5 microcrystals for fast responsive UV-detectors.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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A mitochondria-targeting heptamethine cyanine-chlorambucil formulated polymeric nanoparticle to potentiate native tumor chemotherapeutic efficacy

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00003J, Paper
Jing Liu, Jie Zhang, Yongteng Zhang, Wei Wei, Meixiao Zhan, Zhiren Zhang, Bing Liu, Xianglong Hu, Weiling He
Facile conjugation of chlorambucil with IR775 chloride can afford IR775-Cbl with mitochondria-targeting potency for tumor cells, exhibiting distinct “1 + 1 > 2” tumor inhibition.
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Escape sites from the endo-lysosomal trafficking route manipulate exocytosis of nanoparticles in polar epithelium

Biomater. Sci., 2024, Advance Article
DOI: 10.1039/D4BM00174E, Paper
Lingling Wang, Yuting Li, Xi Liu, Liyun Xing, Ruinan Wu, Yuan Huang
MNPs escaping from early endosomes and late endosomes are prone to entering the ER/GA for efficient basolateral exocytosis. However, MNPs escaping from lysosomes are detained within cells by autophagosomes.
To cite this article before page numbers are assigned, use the DOI form of citation above.
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Nanotechnology-based delivery of therapeutics through the intranasal pathway and the blood–brain barrier for Alzheimer's disease treatment

Biomater. Sci., 2024, 12,2007-2018
DOI: 10.1039/D3BM02003G, Review Article
Mark-Jefferson Buer Boyetey, Yonghyun Choi, Hee-Young Lee, Jonghoon Choi
Drugs for Alzheimer's disease (AD) fail to exhibit efficacy in clinical trials for a number of reasons, a major one being blood–brain barrier (BBB) permeability.
The content of this RSS Feed (c) The Royal Society of Chemistry




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Recent advances in shape memory polymeric nanocomposites for biomedical applications and beyond

Biomater. Sci., 2024, 12,2033-2040
DOI: 10.1039/D4BM00004H, Review Article
Yifan Zheng, Yudi Du, Ling Chen, Wei Mao, Yuan Pu, Steven Wang, Dan Wang
Shape memory polymers (SMPs), which initiate shape transformation in response to environmental stimuli, have attracted significant attention in both academic research and technological innovation.
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Correction: A Y1 receptor ligand synergized with a P-glycoprotein inhibitor improves the therapeutic efficacy of multidrug resistant breast cancer

Biomater. Sci., 2024, 12,2165-2166
DOI: 10.1039/D4BM90022G, Correction
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Yinjie Wang, Zhenqi Jiang, Bo Yuan, Yuchen Tian, Lingchao Xiang, Yanying Li, Yong Yang, Juan Li, Aiguo Wu
The content of this RSS Feed (c) The Royal Society of Chemistry




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A shapeshifting sidekick! ASUS Zenbook Duo (2024)

The dual screen delight is back and updated to offer even more!




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Tips to prepare for the Sociology paper in the UPSC CSE Mains

Sociology is a popular choice for the optional subject in the UPSC Civil Services Exams (Mains). Here are a few tips on how to prepare for this subject




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Employee resource groups shape the inclusion narrative  

Across companies, these units are proving their effectiveness in promoting the LGBTQ+ cause




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New Education Policy aims to shape the youth as per future needs, says Andhra University vice-chancellor

G. Sashibhushan Rao inaugurates the two-day national conference ‘Equity, Diversity, and Inclusion in NEP 2020: Issues, Concerns, and Challenges’ in Visakhapatnam




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A Jacobite miscellany : eight original papers on the rising of 1745-1746 / edited, with an introduction and notes, by Henrietta Tayler, F.R.Hist.Soc.

Oxford : Printed for the Roxburgh Club by Charles Batey at the University Press, MCMXLVIII [1948]




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Papers of the Edinburgh Bibliographical Society : 1890-95.

Edinburgh : Printed for the Society, MDCCCXCVI [1896]




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Home is where wallpapers become a piece of art

With wallpapers as their muse, designers are exploring maximalism through motifs inspired by nature and architecture 



  • Life & Style

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Cape Town Test | Sport, like art, need not make sense; it can be enjoyed still

You can put down the below-par performances in the Cape Town Test to technical deficiencies in batting, yet you come to the philosophical question: Can we really know anything for certain? Also, does everything have to make sense?




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Political Line | Glories of our past — two notions that shape our present




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Newspaper story

Surviving Self-Distancing – Day 8




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DHFL Resolution: Top banks move Apex court against NCLAT order

Some CoC members challenge the NCLAT order and want SC to set it aside



  • Money & Banking

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Water level in Mullaperiyar dam stands at 124.75 feet on November 8, 2024




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Water level in Mullaperiyar dam stands at 124.75 feet on November 9, 2024




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Water level in Mullaperiyar dam stands at 124.60




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Water level in Mullaperiyar dam stands at 124.40 feet on November 11, 2024




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Water level in Mullaperiyar dam stands at 124.20 feet




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Apple may unveil a cheaper Vision Pro in 2025

The cheaper model is also expected to use more plastic instead of the heavier aluminium and glass design that was originally used




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The Franz Boas papers / Regna Darnell, general editor

Lincoln : University of Nebraska Press, [2015]-




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Autophagy-focused Casma Therapeutics debuts with $58.5 million from Third Rock

The biotech will first tackle lysosomal storage disorders




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Chemistry in Pictures: ‘Crystal Landscape’




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BASF, Solenis to combine water, paper chemicals




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David Liu launches Beam Therapeutics to treat genetic diseases with CRISPR base editing

Joined by CRISPR luminaries Feng Zhang and J. Keith Joung, the Harvard chemist raises up to $87 million in funding




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Can single-cell genomics lead to a new wave of drug targets? Celsius Therapeutics thinks so

The start-up, based on the work of Broad Institute scientist Aviv Regev, has raised $65 million to develop therapies for cancer and autoimmune disease




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Accent Therapeutics launches to target the epitranscriptomic RNA code in cancer

With $40 million series A funding, the start-up will develop inhibitors of proteins that make chemical modifications to RNA




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Celsius Therapeutics launches to tap single-cell genomics for drug discovery




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David Liu launches Beam Therapeutics to treat genetic diseases with CRISPR base editing

Joined by CRISPR luminaries Feng Zhang and J. Keith Joung, the Harvard chemist raises up to $87 million in funding




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Stiff-yet-supple plastic can be reshaped and recycled

Dynamic boron-oxygen networks are key to the new material’s unusual properties




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BridgeBio launches CoA Therapeutics to treat a rare neurodegenerative disease

The startup is developing allosteric activators to increase levels of the vital metabolic molecule coenzyme A in pantothenate kinase-associated neurodegeneration




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Chemists synthesize Saturn-shaped molecule

Flat, macrocyclic host captures fullerene guest with CH–π interactions




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Gene therapy start-up Freeline Therapeutics raises $116 million




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BridgeBio licenses compounds from NeuroVive and launches Fortify Therapeutics