pro Quantifying platinum binding on protein-functionalized magnetic microparticles using single particle-ICP-TOF-MS By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00268G, Paper Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Veronica C. Bradley, Benjamin T. Manard, Lyndsey Hendriks, Daniel R. Dunlap, Amber N. Bible, Ada Sedova, Patricia Saint-Vincent, Brian C. Sanders, Hunter B. AndrewsThis work describes an analytical procedure, single particle-inductively coupled plasma-time-of-flight-mass spectrometry (SP-ICP-TOF-MS), that was developed to determine the platinum binding efficiency of protein-coated magnetic microparticles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Proximity hybridization based “turn-on” DNA tweezer for accurate and enzyme-free small extracellular vesicles analysis By pubs.rsc.org Published On :: Anal. Methods, 2024, Accepted ManuscriptDOI: 10.1039/D4AY00487F, PaperJinlin Wu, Xi Mei, Xiaoqin Zhan, Fang Liu, Dongfang LiuSmall extracellular vesicles (sEVs) are a type of extracellular vesicles that carry many types of molecular information. The identification of sEVs is essential for the non-invasive detection and treatment of...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Novel advanced materials and magnetic solid phase extraction as approaches in sample preparation to enhance the analysis of ochratoxin A in peanuts By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00246F, PaperBingchen Wang, Yifan Wang, Xiuyuan Zhang, Kuo HeIn order to improve the detection efficiency of ochratoxin, a superparamagnetic nano-material was synthesized for solid phase extraction of ochratoxin.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections By pubs.rsc.org Published On :: Anal. Methods, 2024, Advance ArticleDOI: 10.1039/D4AY00438H, PaperSai Zhu, Lixuan Dai, Xiaoli Zhong, Weiying LinWe have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro YouTube’s Time-Based UX Problem for Live Sports By www.impressivewebs.com Published On :: Mon, 30 Sep 2024 10:00:00 +0000 I like to play beach volleyball here in the Toronto area. I also watch beach volleyball on YouTube, which includes a lot of live streams from the AVP league in the US. It's a fun sport that I recommend to anyone looking for a new athletic competition to follow. In most leagues and tournaments, beach volleyball games have a 3-set format, with each set finishing when a team reaches 21 points (or higher if they're not yet ahead by 2). The third set (played if needed) will go up to 15 points (again, win by 2). Some leagues/tournaments will play all three sets up to 15. It depends on the venue, tournament, etc. The post YouTube’s Time-Based UX Problem for Live Sports appeared first on Impressive Webs. Full Article UX Web Design Articles
pro NPR and Aadhaar - a confused process By www.thehindubusinessline.com Published On :: Mon, 22 Jul 2013 15:53:25 +0530 Full Article R Dinakaran
pro For a fair probe: On the Kejriwal bail order and CBI conduct By www.thehindu.com Published On :: Mon, 16 Sep 2024 00:47:00 +0530 Kejriwal bail order is a reminder to CBI to dispel perception of bias Full Article Editorial
pro A way out: On the government and doctor-led protests in West Bengal By www.thehindu.com Published On :: Wed, 18 Sep 2024 00:20:00 +0530 The West Bengal government must enable the changes doctors want to see Full Article Editorial
pro Judge and prejudice: On conduct in judicial proceedings By www.thehindu.com Published On :: Fri, 27 Sep 2024 00:10:00 +0530 Judicial officers must be mindful of language that reveal bias Full Article Editorial
pro Western front: On the parties and their prospects in the Maharashtra polls By www.thehindu.com Published On :: Tue, 29 Oct 2024 00:30:00 +0530 Granular factors can determine the outcome in Maharashtra Full Article Editorial
pro Lead optimisation of OXS007417: in vivo PK profile and hERG liability modulation to optimise a small molecule differentiation agent for the potential treatment of acute myeloid leukaemia By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3495-3506DOI: 10.1039/D4MD00275J, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Thomas J. Cogswell, Laia Josa-Culleré, David Zimmer, Sébastien R. G. Galan, Morgan Jay-Smith, Kate S. Harris, Carole J. R. Bataille, Thomas R. Jackson, Douzi Zhang, Stephen G. Davies, Paresh Vyas, Thomas A. Milne, Graham M. Wynne, Angela J. RussellThe optimisation of a class of AML differentiation agents is described to show improved potency, solubility and stability, reduced off target toxicity, and tumour regression in a murine model in vivo.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro SLL-1A-16 suppresses proliferation and induces autophagy in non-small-cell lung cancer cells via the AKT/mTOR signaling pathway By pubs.rsc.org Published On :: RSC Med. Chem., 2024, 15,3460-3468DOI: 10.1039/D4MD00405A, Research ArticleXiaoqin Luo, Jin Wang, Ruichang Wang, Jiabing Lian, Mengnan Guo, Hongrui Zhou, Mengxue Zhang, Zhe Yang, Xiaolong Li, Xianran He, Xiuli BiSchematic of proposed mechanism for the treatment of the SLL-1A-16 inhibiting the proliferation in NSCLC.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro A novel, glutathione-activated prodrug of pimasertib loaded in liposomes for targeted cancer therapy By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00517A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Arianna Amenta, Susanna Comi, Marcelo Kravicz, Silvia Sesana, Antonia Antoniou, Daniele Passarella, Pierfausto Seneci, Sara Pellegrino, Francesca ReA novel, glutathione-activated prodrug of pimasertib (PROPIMA) has been developed. PROPIMA showed ability to inhibit tumour cell migration and proliferation controlled over time, while also achieving a high incorporation rate into liposomes.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Introduction to the themed collection in honour of Professor Christian Leumann By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD90039A, EditorialMarcel Hollenstein, Eugen StulzMarcel Hollenstein and Eugen Stulz introduce the cross-journal themed collection celebrating Christian Leumann’s retirement.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Development, biological evaluation, and molecular modelling of some benzene-sulfonamide derivatives as protein tyrosine phosphatase-1B inhibitors for managing diabetes mellitus and associated metabolic disorders By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00594E, Research ArticleNagat Ghareb, Khaled M. Darwish, Mohamed S. Nafie, Ranwa Elrayess, Noha M. Abourobe, Shaimaa A. Fattah, Reem M. Hazem, Eman T. Mehanna, Ranza ElrayessOne benzene-sulfonamide derivative exhibited potent protein tyrosine phosphatase-1B inhibition for managing diabetes mellitus and associated metabolic disorders.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Correction: Anti-schistosomal activity and ADMET properties of 1,2,5-oxadiazinane-containing compound synthesized by visible-light photoredox catalysis By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD90044H, Correction Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Kennosuke Itoh, Hiroki Nakahara, Atsushi Takashino, Aya Hara, Akiho Katsuno, Yuriko Abe, Takaaki Mizuguchi, Fumika Karaki, Shigeto Hirayama, Kenichiro Nagai, Reiko Seki, Noriko Sato, Kazuki Okuyama, Masashi Hashimoto, Ken Tokunaga, Hitoshi Ishida, Fusako Mikami, Kofi Dadzie Kwofie, Hayato Kawada, Bangzhong Lin, Kazuto Nunomura, Toshio Kanai, Takeshi Hatta, Naotoshi Tsuji, Junichi Haruta, Hideaki FujiiTo cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro A decade of pyridine-containing heterocycles in US FDA approved drugs: a medicinal chemistry-based analysis By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00632A, Review ArticleAshish Ranjan Dwivedi, Shivani Jaiswal, Deepak Kukkar, Roshan Kumar, Thakur Gurjeet Singh, Mahendra Pratap Singh, Abhay M. Gaidhane, Sorabh Lakhanpal, K. Nagendra Prasad, Bhupinder KumarThe present review is a concerted effort to cover drugs bearing pyridine rings approved in the last decade, and it provides thorough discussion and commentary on their pharmacokinetics and pharmacodynamics together with in-depth structural analysis.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Miniaturized click chemistry and direct screening facilitate the discovery of triazole piperazine SARS-CoV-2 Mpro inhibitors with improved metabolic stability By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00555D, Research ArticleShenghua Gao, Letian Song, Bing Ye, Mianling Yang, Junyi Li, Manyu Gu, Ann E. Tollefson, Karoly Toth, Peng Zhan, Xinyong LiuThe continuous mutational nature of SARS-CoV-2 and its inter-species' similarities emphasize the urgent need to design and develop more direct-acting antiviral agents against highly infectious variants.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro A novel approach for the synthesis of the cyclic lipopeptide globomycin By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00685B, Research Article Open Access   This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Samantha J. Bann, Stephen A. CochraneLipid swapping: a new approach for the synthesis of globomycin that allows for facile lipid diversification.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Design, synthesis, and biological evaluation of pyrazole–ciprofloxacin hybrids as antibacterial and antibiofilm agents against Staphylococcus aureus By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00623B, Research ArticleOjaswitha Ommi, Priyanka Sudhir Dhopat, Shashikanta Sau, Madhu Rekha Estharla, Srinivas Nanduri, Nitin Pal Kalia, Venkata Madhavi YaddanapudiA series of pyrazole–ciprofloxacin hybrids were designed, synthesized, and tested for antibacterial activity against Staphylococcus aureus, Pseudomonas aeruginosa, and Mycobacterium tuberculosis, aiming to combat antibiotic resistance.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Synthesis, in silico and bio-evaluation studies of new isothiocyanate derivatives with respect to COX inhibition and H2S release profiles By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00495G, Research ArticleYakup Berkay Yilmaz, Tuğba Güngör, Serhat Dönmez, Hazal Nazlıcan Atalay, Pınar Siyah, Serdar Durdağı, Mehmet Ay, Tugba Boyunegmez TumerNew isothiocyanate derivatives (I1–3 and I1a–e) were synthesized and screened for their anti-inflammatory activities and H2S-releasing capacities. Compounds I1 and I1c demonstrated the most potent and selective COX-2 inhibition.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro meso-Substituted AB3-type phenothiazinyl porphyrins and their indium and zinc complexes photosensitising properties, cytotoxicity and phototoxicity on ovarian cancer cells By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Advance ArticleDOI: 10.1039/D4MD00601A, Research Article Open Access   This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Brém Balázs, Bianca Stoean (Vasile), Éva Molnár, Eva Fischer-Fodor, Ovidiu Bălăcescu, Raluca Borlan, Monica Focsan, Adriana Grozav, Patriciu Achimaş-Cadariu, Emese Gál, Luiza GainaNew meso-substituted AB3-type phenothiazinyl porphyrins and ferrocenylvinyl phenothiazinyl porphyrin were synthesised by Suzuki–Miyaura and Mizoroki–Heck cross-coupling reactions, respectively.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Property-based optimisation of PROTACs By pubs.rsc.org Published On :: RSC Med. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4MD00769G, OpinionJames Scott, Iacovos Michaelides, Markus SchadePROTACs are an emerging therapeutic approach towards targeted protein degradation. This article examines the leading examples of this modality that are in clinical development through the prism of their physicochemical...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
pro Duo arrested for possession of banned tobacco products worth ₹3 lakh in Tiruchi By www.thehindu.com Published On :: Wed, 06 Nov 2024 18:23:30 +0530 Full Article Tiruchirapalli
pro Property owners block the entrance to Balasubramanya temple in Karur By www.thehindu.com Published On :: Thu, 07 Nov 2024 17:35:45 +0530 Full Article Tiruchirapalli
pro Udhayanidhi lays foundation stone for infrastructure development projects in Thanjavur district By www.thehindu.com Published On :: Thu, 07 Nov 2024 18:48:04 +0530 Buildings at the Government Arts and Science College, Thirukkattupalli, construction of compound wall and an indoor stadium at the Government Rajah Serfoji College, Thanjavur, are among the projects Full Article Tiruchirapalli
pro HR&CE plans to bring properties around the Vennaimalai Temple under tenants list By www.thehindu.com Published On :: Thu, 07 Nov 2024 19:36:32 +0530 The HR&CE department has cleared 34 properties around the Balasubramanyaswamy Temple at Vennaimalai in Karur district as per the High Court orders Full Article Tiruchirapalli
pro Association holds protest against delay in Anna University’s staff absorption, promotions By www.thehindu.com Published On :: Sat, 09 Nov 2024 22:02:50 +0530 Full Article Tiruchirapalli
pro 544: Feedback, RSS Talk, Arc Brower, and Product Talk By shoptalkshow.com Published On :: Mon, 05 Dec 2022 08:15:42 +0000 Getting feedback for what you're building or writing, RSS feed reminiscing, Arc browser thoughts, products that didn't make that should have. Full Article All Episodes browsers Feedback rss
pro 558: Esoteric Weird Content Editable Problems with Kristin Valentine By shoptalkshow.com Published On :: Mon, 27 Mar 2023 07:34:54 +0000 Kristin Valentine from Vox joins the show to talk about text editor CMS fun across multiple sites, Vox's Chorus, The Verge redesign, sharing Design Systems, theming articles, and a fun new game called "Can Your Text Editor Do This??" Full Article All Episodes CMS editor vox
pro 569: Apple’s Web Apps, Meta Quest and Vision Pro, and Missing Sticky Headers By shoptalkshow.com Published On :: Mon, 12 Jun 2023 07:20:15 +0000 How do you point out things in a UI? Are Arc Boosts the end of the web? What do you think of VR and AR / Vision Pro and Meta Quest? And what do you do when the sticky header goes missing? Full Article All Episodes meta quest vision pro Web Apps
pro 572: Text Sqwunch Property, Figma Developer Mode, Stripe Elements By shoptalkshow.com Published On :: Mon, 03 Jul 2023 08:24:15 +0000 Show DescriptionDave reports back from the Figma Conference, how to build a better developer to designer bridge, do clients really want to update their website, using Stripe in 2023, permissions and sharing, and are you feeling overwhelmed by CSS in 2023? Listen on Website →Links Config 2023 | Figma’s Annual Conference Figma Visual Studio Code […] Full Article All Episodes CSS figma stripe
pro 575: CSS Errors, Proxy and Reverse Proxy, and What’s The Edge? By shoptalkshow.com Published On :: Mon, 24 Jul 2023 09:00:16 +0000 Bluesky adds first class support for urls as a username, text-wrap pretty update, sqwunching text update, should CSS spit out errors, anchor functionality, what does the edge mean, eSports and bowling, how to test websites on slower CPUs, and what does proxy or reverse proxy mean? Full Article All Episodes edge proxy text-wrap
pro 578: Customer Support, P3 Color, Dave on Productivity, and Mobile vs Desktop By shoptalkshow.com Published On :: Mon, 14 Aug 2023 07:24:25 +0000 Is Apple's Numbers amazing or the worst? Customer support at various levels of software, Figma and P3 color, imagining a colorspace property in CSS, what's Dave doing for productivity, how has offloading CSS Tricks affected Chris, and should we build different websites for mobile vs desktop? Full Article All Episodes css tricks p3 Productivity Tools
pro 610: TypeScript in 2024, Signals, Productivity Sniped, and Follow Up By shoptalkshow.com Published On :: Mon, 08 Apr 2024 08:38:19 +0000 Dave's about to be eclipsed, the state of TypeScript in 2024, signals stage zero proposal, corrections on accessibility in frameworks (thanks!), web apps for better collaborative writing, getting productivity sniped, the problem with email may be you, indieweb follow up, and ultimate guitar tab apps. Full Article All Episodes eclipse Email signals typescript
pro 620: Cloudflare #HotDrama, Auth, and Prototyping Thoughts By shoptalkshow.com Published On :: Mon, 17 Jun 2024 08:27:24 +0000 Show DescriptionWe dive a bit deeper into the Cloudflare drama of the past couple of weeks, Instagram ads vs Cara art, what to do about Auth in your app, pre-negging any sponsorships, prototyping and feedback on projects, and ideas for future topics. Listen on Website →Links Cloudflare took down our website after trying to force […] Full Article All Episodes Cloudflare Prototyping Web Components
pro 637: Approachable Open Source with Brian Muenzenmeyer By shoptalkshow.com Published On :: Mon, 14 Oct 2024 08:28:34 +0000 Brian Muenzenmeyer joins the show to talk about his book, Approachable Open Source, ways we can make open source easier to get in, important conversations around funding and supporting open source, and whether money helps maintainers deal with burnout or not? Full Article All Episodes books Money Open Source
pro 640: Navigating the Pros and Cons of Web Components By shoptalkshow.com Published On :: Mon, 04 Nov 2024 08:52:16 +0000 Riffing off a Dave Rupert blog post, Chris and Dave talk through the pros and cons of web components, when to use them, when it's a bad idea to use them, what would it take to make the Next.js of web components, and how long until we don't need anymore frameworks? Full Article All Episodes Javascript Web Components
pro Improve quality of indoor air By www.thehindu.com Published On :: Fri, 13 Feb 2015 17:10:54 +0530 Outdoor air pollutants are impacting the indoor environment and builders have to take remedial measures, says M.A. Siraj Full Article Green Living
pro The pros and cons of spouses teaming up as co-founders By www.thehindubusinessline.com Published On :: Sun, 29 Sep 2024 20:40:00 +0530 How do married co-founders navigate the personal and professional ties at work Full Article Emerging Entrepreneurs
pro Unlocking renewable energy from industrial waste: Biogas production from spent wash By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 15:51:29 +0530 It is a sustainable solution for industrial waste management and renewable energy generation Full Article Agri Business
pro Idukki project leapfrogs ‘endangered’ list By www.thehindubusinessline.com Published On :: Sun, 13 Oct 2024 20:06:56 +0530 Local enthusiasts pitch in to bring amphibian species back from the brink of extinction Full Article Clean Tech
pro Morning runs, protein-packed breakfast, and a rest day By www.thehindubusinessline.com Published On :: Sun, 20 Oct 2024 20:19:00 +0530 The daily quest to balance work, health, and personal life Full Article Pulse
pro L&T eyes CIS region for solar projects By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 18:09:30 +0530 After West Asia, oil-rich countries like Uzbekistan are generating demand for solar energy Full Article Clean Tech
pro Bengaluru startup develops new tech for battery recycling, begins production By www.thehindubusinessline.com Published On :: Sun, 27 Oct 2024 18:13:56 +0530 Li-ion battery recycler Metastable Materials launches commercial ops Full Article Clean Tech
pro Concussion: FIFA kicks off ‘suspect and protect’ drive By www.thehindubusinessline.com Published On :: Sun, 03 Nov 2024 19:30:47 +0530 Campaign raises awareness that concussion is a traumatic brain injury and a risk to every player on the pitch Full Article Pulse
pro Gopal Rai calls meeting over Winter Action Plan progress By www.thehindu.com Published On :: Tue, 05 Nov 2024 01:05:00 +0530 Full Article Delhi
pro Delhi L-G inspects Gole Market restoration project By www.thehindu.com Published On :: Wed, 06 Nov 2024 01:16:27 +0530 Full Article Delhi
pro Delhi HC permits man to buy The Satanic Verses after Centre fails to produce notification banning the book By www.thehindu.com Published On :: Thu, 07 Nov 2024 20:30:42 +0530 India was one of the first countries to ban the book’s import and sale, citing concerns over its content being offensive to the Muslim community Full Article India
pro Leaves taken by doctors during RG Kar protest to be adjusted against their official quota: AIIMS Delhi By www.thehindu.com Published On :: Fri, 08 Nov 2024 01:12:12 +0530 Full Article Delhi