Primary season is now upon us. Here are three ideas for teaching in the wake of the Iowa caucus fallout.

From time to time, but not very often, former special-teams coordinators become NFL head coaches.

The legislature sent a proposal last week to Gov. Jim Justice's desk to shutter the state's advisory education and the arts department, leaving the Gayle Manchin and her staff in the lurch.

Abnormal neuronal morphological features, such as dendrite branching, axonal branching, and spine density, are thought to contribute to the symptoms of depression and anxiety. However, the role and molecular mechanisms of aberrant neuronal morphology in the regulation of mood disorders remain poorly characterized. Here, we show that neuritin, an activity-dependent protein, regulates the axonal morphology of serotonin neurons. Male neuritin knock-out (KO) mice harbored impaired axonal branches of serotonin neurons in the medial prefrontal cortex and basolateral region of the amygdala (BLA), and male neuritin KO mice exhibited depressive and anxiety-like behaviors. We also observed that the expression of neuritin was decreased by unpredictable chronic stress in the male mouse brain and that decreased expression of neuritin was associated with reduced axonal branching of serotonin neurons in the brain and with depressive and anxiety behaviors in mice. Furthermore, the stress-mediated impairments in axonal branching and depressive behaviors were reversed by the overexpression of neuritin in the BLA. The ability of neuritin to increase axonal branching in serotonin neurons involves fibroblast growth factor (FGF) signaling, and neuritin contributes to FGF-2-mediated axonal branching regulation in vitro. Finally, the oral administration of an FGF inhibitor reduced the axonal branching of serotonin neurons in the brain and caused depressive and anxiety behaviors in male mice. Our results support the involvement of neuritin in models of stress-induced depression and suggest that neuronal morphological plasticity may play a role in controlling animal behavior.

The superior colliculus receives a direct projection from retinal ganglion cells. In primates, it remains unknown if the same ganglion cells also supply the lateral geniculate nucleus. To address this issue, a double-label experiment was performed in two male macaques. The animals fixated a target while injection sites were scouted in the superior colliculus by recording and stimulating with a tetrode. Once suitable sites were identified, cholera toxin subunit B-Alexa Fluor 488 was injected via an adjacent micropipette. In a subsequent acute experiment, cholera toxin subunit B-Alexa Fluor 555 was injected into the lateral geniculate nucleus at matching retinotopic locations. After a brief survival period, ganglion cells were examined in retinal flatmounts. The percentage of double-labeled cells varied locally, depending on the relative efficiency of retrograde transport by each tracer and the precision of retinotopic overlap of injection sites in each target nucleus. In counting boxes with extensive overlap, 76–98% of ganglion cells projecting to the superior colliculus were double labeled. Cells projecting to the superior colliculus constituted 4.0–6.7% of the labeled ganglion cell population. In one particularly large zone, there were 5,746 cells labeled only by CTB-AF555, 561cells double labeled by CTB-AF555 and CTB-AF488, but no cell labeled only by CTB-AF488. These data indicate that retinal input to the macaque superior colliculus arises from a collateral axonal branch supplied by ~5% of the ganglion cells that project to the lateral geniculate nucleus. Surprisingly, there exist no ganglion cells that project exclusively to the SC.

FAO and China have signed a two-year tripartite cooperation agreement worth about N$10.5 million (US$1.5 million) that will boost the efforts of local farmers in Namibia. The agreement, which is [...]

The monthly publications updates produced by the Publications branch of the FAO Office of Communications are now available in English, Chinese and French.  

The newsletters highlight key publications available in the respective [...]

Three sites in China - an ancient tea-producing area, a nomadic livestock-rearing region and a rain-fed stone terrace farming system - were formally recognised  as Globally Important Agricultural Heritage [...]

The monthly FAO publications updates produced by the Publications Branch of the FAO Office of Communications are available in English, French and Chinese.

The newsletters highlight key publications available [...]

Must we choose between food security and climate neutrality? How do we make sure food imports are safe? How do low-income countries move up the food [...]

The monthly FAO publications updates produced by the Publications Branch of the FAO Office of Communications are available in English, French and Chinese.

The newsletters highlight key publications available [...]

The first computer is thought to be the invention of a 19th century mathematician

Researchers are able to track Venus flytrap plants that were stolen from protected areas

Read more at http://blogs.smithsonianmag.com/aroundthemall/2009/12/tai-shan-will-return-to-china/ Visitors to the National Zoo have enjoyed watching their baby panda grow up over the last four years.

In July 1925, a young science teacher named John Scopes was in court, accused of contravening the Butler Act—a Tennessee law that prohibited the teaching of evolution in schools.

Whether you're a passionate astronomer or a beginner eager to explore the cosmos, join us as we deep-dive into seasonal skywatching. Gain valuable insights into identifying meteors, stars, and fascinating deep-sky objects that grace the night sky. Interested in learning more? Check out this piece from Smithsonian Magazine on the celestial events to watch in 2024: https://www.smithsonianmag.com/science-nature/nine-dazzling-celestial-events-to-watch-in-2024-180983505/ And don't forget to subscribe to our channel for more exciting videos exploring the wonders of the natural world. --- Digital Editorial Director: Brian Wolly Supervising Producer & Scriptwriter: Michelle Mehrtens Video Editor: Sierra Theobald

A new “health check” for our planet sounds an alarm bell on rising ocean acidification, which is driven by carbon dioxide levels in the atmosphere

As hundreds of motorists take to the desert, their tracks damage the massive geoglyphs made by Indigenous groups in northern Chile

New research has revealed that the mysterious white substance found alongside three ancient mummies was once a soft cheese called kefir

A recurrent nova, known as the Blaze Star or T Coronae Borealis, is predicted to soon appear in the night sky. But the exact timing of the rare eruption remains unknown

Scientists converted the patient’s own cells into blood sugar-regulating cell clusters before injecting them back into her abdomen—and one year later, she still doesn't need insulin injections

"Transforming Energy," the artist's first museum show in China, focuses on "artworks and objects that actively engage the audience"

Hundreds of artifacts have been unearthed at a burial mound in the city of Chifeng, but researchers are particularly intrigued by the six-inch-long object

A "staggering array" of markings have been hiding in plain sight carved into the walls of Gainsborough Old Hall, a 500-year-old home in Lincolnshire, England

Laboratory study of natural populations of mosquitoes can play a key role in determining the underlying causes of variation in burdens of mosquito-borne disease. Aedes aegypti is the main vector of the viruses that cause dengue, chikungunya, Zika, and yellow fever, making it a high priority for laboratory study. Ae. aegypti eggs provide an ideal starting point for new laboratory colonies. Eggs can be collected using ovicups, which are small plastic cups lined with seed-germination paper and partially filled with leaf-infused H₂O. Once collected, dry eggs will remain viable for months and can be safely transported long distances back to the laboratory as long as they are properly stored. This protocol provides step-by-step instructions for preparing for collecting, storing, and hatching Ae. aegypti eggs and has successfully yielded laboratory colonies from locations across both the native and invasive range of this species.

Many of the buns sold at China Pastry are classics you would find in bakeries in Hong Kong and Chinatowns all over the world. It's taken decades of hard work, but owners Sally and Tony Wong say they've established a nice flow together over the years.

The P.E.I. Woodlot Owners Association is encouraging its members to boost the biodiversity of their woods with different varieties of trees and shrubs. As CBC's Nancy Russell reports, the goal is to provide habitat for endangered species and protect the forests from future disasters like post-tropical storm Fiona.

A driver killed 35 people and severely injured another 43 when he deliberately rammed his car into people exercising at a sports centre in the southern Chinese city of Zhuhai, police said Tuesday.

The impact of Donald Trump's election win on Nov. 5 will be felt globally, especially in China — one of the world's emerging superpowers and one of the United States' biggest trading partners. The relationship could also affect Canada.

Austrian manufacturer also optimizes creation of assembly documentation and related bills of material

Solutions Catch Problems Early and Drive Cost Out of Designs

Ramac Analyzes Design With SolidWorks SustainabilityXpress, Finds Alternatives That Consume Fewer Resources

SolidWorks CAD Software Enables Engineering Students to Fit ‘CubeSat’ Components Into a Four-Inch Square Box

#1 3D mechanical design software helps company quickly design very large assemblies

Besser Company has significantly compressed its mold design cycle

Software will foster supply chain efficiency through better customer, partner, supplier communication

Company purchases 80 licenses of SolidWorks after benchmark testing demonstrates 3x to 7x performance advantage

SolidWorks' dominance in Mexican industry prompts purchase of 300 seats at leading academic institution

Customers will be able to pick a flavor and a mix-in and walk off with fresh dessert in less than a minute

New 3D CAD software increases productivity, quality, and efficiency

Training on 3D CAD application gives students vital skills for competing in world engineering market

Longtime SOLIDWORKS and COSMOS customer reduces costs and time to market

One of the country's largest horticulture machine makers blazes new trails with 3D CAD software

Zhejiang Sanhua Co., Ltd. Purchases 160-Plus Seats of CAD, Simulation, and Product Data Management Software

China's economic stimulus in 2009 unleashed a bull market among commodities. Will its 2024 stimulus have the same impact?

Evidence suggests that the earlier Chinese Salt Typhoon breach of American telecoms may have led to the potential hacking of two presidential campaign officials' iPhones.

The developer of an app dropped from the App Store in China has filed a lawsuit that challenges Apple's overall practices, as well as damages of $420,000.