Title: How Does Melatonin Make You Feel, and Are There Side Effects?
Category: Health and Living
Created: 7/15/2022 12:00:00 AM
Last Editorial Review: 7/15/2022 12:00:00 AM

Title: In Early Trial, Targeted Therapy Fights Advanced Melanoma
Category: Health News
Created: 8/25/2010 6:10:00 PM
Last Editorial Review: 8/26/2010 12:00:00 AM

Title: New Drug May Treat Advanced Melanoma
Category: Health News
Created: 8/26/2010 11:04:00 AM
Last Editorial Review: 8/26/2010 11:04:24 AM

Title: Could a Laser Skin Test Someday Replace Biopsy to Spot Melanoma?
Category: Health News
Created: 8/21/2015 12:00:00 AM
Last Editorial Review: 8/24/2015 12:00:00 AM

Title: Moles Not Most Likely Spot for Melanomas
Category: Health News
Created: 8/29/2017 12:00:00 AM
Last Editorial Review: 8/29/2017 12:00:00 AM

Title: Spotting the Signs of Deadly Melanoma Skin Cancers
Category: Health News
Created: 8/22/2021 12:00:00 AM
Last Editorial Review: 8/23/2021 12:00:00 AM

Sleep is a fundamental feature of life for virtually all multicellular animals, but many questions remain about how sleep is regulated by circadian rhythms, homeostatic sleep drive that builds up with wakefulness, and modifying factors such as hunger or social interactions, as well as about the biological functions of sleep. Substantial headway has been made in the study of both circadian rhythms and sleep in the fruit fly Drosophila melanogaster, much of it through studies of individual fly activity using Drosophila activity monitors (DAMs). Here, we describe approaches for the activation of specific neurons of interest using optogenetics (involving genetic modifications that allow for light-based neuronal activation) and thermogenetics (involving genetic modifications that allow for temperature-based neuronal activation) so that researchers can evaluate the roles of those neurons in controlling rest and activity behavior. In this protocol, we describe how to set up a rig for simultaneous optogenetic or thermogenetic stimulation and activity monitoring for analysis of sleep and circadian rhythms in Drosophila, how to raise appropriate flies, and how to perform the experiment. This protocol will allow researchers to assess the causative role in the regulation of sleep and activity rhythms of any genetically tractable subset of cells.

Sleep is important for survival, and the need for sleep is conserved across species. In the past two decades, the fruit fly Drosophila melanogaster has emerged as a promising system in which to study the genetic, neural, and physiological bases of sleep. Through significant advances in our understanding of the regulation of sleep in flies, the field is poised to address several open questions about sleep, such as how the need for sleep is encoded, how molecular regulators of sleep are situated within brain networks, and what the functions of sleep are. Here, we describe key findings, open questions, and commonly used methods that have been used to inform existing theories and develop new ways of thinking about the function, regulation, and adaptability of sleep behavior.

President-elect Donald Trump announced a flurry of appointments Tuesday for key posts in his new administration, including former Director of National Intelligence John Ratcliffe to lead the CIA and the expected nomination of South Dakota Gov. Kristi Noem to head the Department of Homeland Security.

President-elect Trump announced on Tuesday that Kristi Noem is his pick for secretary of the Department of Homeland Security.

Trump nominated Republican South Dakota Gov. Kristi Noem to serve as his Secretary of the Department of Homeland Security (DHS).

The post Trump Nominates Kristi Noem for Secretary of Department of Homeland Security appeared first on Breitbart.

Peruvanam Satheesan Marar recalls his initiation into the percussion ensemble and how he gained expertise in playing different instruments

Marvel vs. Capcom Fighting Collection: Arcade Classics ($49.99) As a fan of Marvel, Capcom, and fighting games back in the …

Continue reading "SwitchArcade Review Round-Up: ‘Marvel vs. Capcom Fighting Collection’, ‘Yars Rising’, & ‘Rugrats: Adventures in Gameland’"

The two-term governor of South Dakota has been a loyal Trump ally. In her new role, Noem would oversee immigration, an issue Trump campaigned heavily on.

Video gallery Spot Skinchecker

Eva Longoria :30 English

Abingdon, Oxon ; New York, NY : Routledge, 2023.

Houndmills, Basingstoke ; New York, NY : Palgrave Macmillan, 2014.

Hoboken, NJ : John Wiley & Sons, Inc., 2022.

Manchester : Manchester University Press, [2020]

Looking at the red carpet arrivals.

Distinct dance forms exploring the rich tapestry of traditions marked the “Saare Jahan Se Accha” festival in New Delhi.

Founder & CEO, Khyaal, Hemanshu Jain, on his exercise routine, practising mindful eating and more.

Rang-Sangam brought different forms of dance and music on one stage.

Noem faced widespread backlash in April when she wrote in a memoir that she shot to death an "untrainable" dog that she "hated" on her family farm

UAS Vice-Chancellor P. L. Patil said that the main objective of this year’s Krishi Mela is to provide information on various aspects of climate change to farmers

The exhibition was launched by Revenue Divisional Officer S. Venkata Rao and can be called as the perfect place to shop for college-going girls.

Book on ‘Prahlada Charitramu’ was released

Union Minister for Food Processing Industries Chirag Paswan inaugurates Mela at the Rajiv Gandhi Centre for Biotechnology, in Thiruvananthapuram, on October 29

The Krishi Mela will be held on the GKVK campus of UAS-B from November 14 to 17

Odisha has moved a tigress from Maharashtra to its Similipal to address the increasing number of pseudo-melanistic tigers

Government reached the doorsteps of those who had never received any benefits: Modi

When Jawa Motorcycles owner Jiri Gerle sold the legendary but defunct brand to Classic Legends (part-owned by Mahindra & Mahindra), he had one request to the new owners: Please do bring the brand back to its homeland -- the Czech Republic.

Letter submitted by Marc R. Rosenblum, Deputy Director, U.S. Immigration Program, at the request of the Minority Staff of the House Oversight and Government Reform Committee for the February 25, 2015 joint subcommittee hearing reviewing apprehension, detention, and release policies regarding unauthorized immigrants.