Hem Sapkota, Jonathan D. Wren, and Gary J. Gorbsky

Centrosomes focus microtubules to promote mitotic spindle bipolarity, a critical requirement for balanced chromosome segregation. Comprehensive understanding of centrosome function and regulation requires a complete inventory of components. While many centrosome components have been identified, others may yet remain undiscovered. We have used a bioinformatics approach, based on "guilt by association" expression to identify novel mitotic components among the large group of predicted human proteins that have yet to be functionally characterized. Here we identify Chondrosarcoma-Associated Gene 1 (CSAG1) in maintaining centrosome integrity during mitosis. Depletion of CSAG1 disrupts centrosomes and leads to multipolar spindles more effectively in cells with compromised p53 function. Thus, CSAG1 may reflect a class of "mitotic addiction" genes whose expression is more essential in transformed cells.

While the Federal Motor Carrier Safety Administration’s (FMCSA) Safety Measurement System (SMS) used to identify commercial motor vehicle carriers at high risk for future crashes is conceptually sound, several features of its implementation need improvement, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

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Exploits in escarole: See what happens when a mom who's not exactly fond of green veggies forks over $900 for nine months of fresh produce.

Farmers who were once wary of selling produce to ‘city people’ now have 300 regular customers, make more money, and don't get headaches.

Convenient tollway and business drop-off points, plus health insurance stipends, attract a new group of local veggie eaters.

If you run out of your weekend farmers market buys by the middle of the week, an organic produce delivery program can help tide you over.

Think ahead to ensure that you're getting local foods for as much of the year as you can.

CSA membership carries with it some unexpected fringe benefits. Here's what you’ll be able to do!

600,000 travelers left around the world when 178-year-old tour company Thomas Cook suddenly closed for good. Can you protect yourself in the future?

Leading athletic recruiting firm announces top 100 colleges and universities for athletic programming and academics.

NCSA's Suite of Recruiting Solutions to be Integrated into Zero Gravity Basketball Tournaments and Showcases

Dr. Barath has been endorsed by Marquis Who's Who as a leader in the medical industry

Eyewear giant Specsavers has admitted that the personal information of some clients in Queensland is missing and may have been stolen.

České aerolinie obnoví v pondělí 18. května provoz na čtyřech svých linkách. A to do Amsterdamu, Frankfurtu, Paříže a Stockholmu. O týden později začnou letadla létat do dalších tří destinací.

What’s inside? Here are the questions answered in today’s reader mailbag, boiled down to summaries of five or fewer words. Click on the number to jump straight down to the question. 1. Using my stimulus check 2. Gas prices and hybrid cars 3. Worried about returning to work 4. Wedding planning suggestions? 5. Safely storing cash at home 6. CSA and safety 7. Financial success and self-worth 8. Figuring out break-even point 9. What’s the plan after unemployment? 10. Castile […]

The post Questions About Weddings, Windfalls, Castile Soap, Hybrid Cars, CSAs and More appeared first on The Simple Dollar.

Dentists’ comfort levels and perceived roles in discussing and administering the human papillomavirus vaccine appear to vary, according to the results of an American Dental Association Clinical Evaluators Panel survey published in The Journal of the American Dental Association.

Rep. McSally Visits Microchip Executives to Discuss Semiconductor Supply Chain Resilience in the U.S. Amid Defense Industrial Base Report Findings

Microtrottoir CSA – Club Med

Company: Conneqt Business Solutions Limited
Qualification: 12th Class (XII)
Experience: 0 to 5
location: Thane
Ref: 24827698
Summary: Urgent Hiring For WORK FROM HOME # Graduate fresher/ undergrads. # Age below 40. # Experience or freshers # Good Communication Skill # Telephonic Interview

The indictment stated a designer, performance-enhancing substance was administered to Maximum Security in 2019 and, if that charge is proven, it could cost connections the $10m first prize.

Precious time of the nation and its leadership is being wasted on a non-issue, namely Union Public Service Commission (UPSC)’s new Civil Service Aptitude Test (CSAT).

With the announcement of JEE Advanced results 2018 , the bells are about to ring for the counselling event to begin. Most of the students are aware of the Joint Seat Allocation Authority (JoSAA), which is responsible for the seat allotment

Cham : Springer, 2019.

Online Resource

Online Resource

PME Conference (40th : 2016 : Szeged, Hungary)

Berlin ; New York : Springer, [2005]

As a part of its ongoing Series B Funding, DocsApp has raised $9.5 million (₹72.5 crore) from Bessemer Venture Partners India, Fusian Capital, Rebrigh