But the centers, slated to open Monday, are currently limited to children of healthcare and transit workers and first-responders - and advocates worry homeless students will be left behind.

Blood centers are ramping up efforts to collect plasma from people who recovered from COVID-19 in hopes their coronavirus antibodies could save lives.

L.A. Unified officials have killed a plan to open 40 family resource centers. The district still will distribute food.

The Center for Research & Education in Technology is encouraging dental schools to find out how to participate in its program and learn about the benefits to the school and its students.

The Health Resources and Services Administration says it is working to keep health centers and health center program partners updated on the latest information regarding COVID-19.

Rockville, Maryland : National Institute on Drug Abuse, 1981.

Three-fourths of US preschool-age children are in child care; many are not achieving recommended levels of physical activity. Daily physical activity is essential for motor and socioemotional development and for the prevention of obesity. Little is known about physical-activity barriers in child care.

Injury and school-readiness concerns may inhibit children’s physical activity in child care. Fixed playground equipment that meets licensing codes is unchallenging and uninteresting to children. Centers may cut time and space for gross motor play to address concerns about school readiness. (Read the full article)

The National Vaccine Advisory Committee highlighted the importance of settings complementary to the medical home for immunization delivery among adolescents, including school-based health centers (SBHCs). The effectiveness and cost of recall for immunizations in SBHC settings has not been studied.

SBHC-based recall was effective in improving immunization rates among adolescents, with effects sizes exceeding those achieved in practice settings. Average costs per child who was immunized ranged from $1.12 to $2.34 in 3 schools, but was $6.87 in 1 school. (Read the full article)

School-based health centers (SBHCs) are known to increase access to medical care and mental health services for at-risk adolescents. Policymakers have suggested that SBHCs could function as patient-centered medical homes, but SBHCs have not been evaluated in that context.

Using the constructs of the patient-centered medical home as defined by the American Academy of Pediatrics (accessibility, continuity, comprehensiveness, family-centeredness, coordination, and compassion), this study shows that SBHCs have the potential to function as medical homes from the perspective of adolescents and parents. (Read the full article)

Cyber dating abuse victimization has been correlated with physical, sexual, and psychological adolescent relationship abuse.

This is the first clinic-based study of cyber dating abuse. Forty-one percent of youth reported cyber dating abuse victimization, female more than male respondents. Compared with nonexposed youth, abuse victims reported more sexual assault; female victims reported more contraceptive nonuse and reproductive coercion. (Read the full article)

Mary Ellen Avery
Jan 1, 1987; 79:26-30
ARTICLES

Cynthia L. Ogden
Jan 1, 2002; 109:45-60
ARTICLES

An Epyc server can contain up to 4TB of memory and 128 lanes of PCIe, making it a worthy Intel Xeon competitor.

Agency: DOE Closing Date: 5/27/2020

DOVER – Bayhealth and Beebe Medical Centers have each received $750,000 in federal grant funds from the U.S. Department of Health and Human Services (HHS), through the Health Resources and Services Administration (HRSA) to develop rural residency programs. HRSA awarded approximately $20 million in Rural Residency Planning and Development Program (RRPD) grants to recipients across […]

DEPARTMENT OF HEALTH AND SOCIAL SERVICES: Division of Health Care Quality

Email from Governor John Carney:   This is an uncertain time, and Delawareans have understandable questions about the potential impact of coronavirus (COVID-19) on their families and communities.   We’ve repeatedly heard versions of this question:  Why would the state close schools, but recommend that childcare centers remain open?   The current guidance from the Delaware Division of […]

Some of the asylum centers are set to be closed in Denmark after authorities disclosed that applications for asylum seekers are being processed faster now and asylum seekers who were (or, have been) rejected are about to leave the country voluntarily.At…

Alphabet Inc.’s Google said it would invest 1 billion euros ($1.1 billion) to expand its data center infrastructure in the Netherlands.

Alphabet Inc.’s Google said it would invest 1 billion euros ($1.1 billion) to expand its data center infrastructure in the Netherlands.

Alphabet Inc.’s Google said it would invest 1 billion euros ($1.1 billion) to expand its data center infrastructure in the Netherlands.

Apple Inc. plans to spend 1.7 billion euros ($1.9 billion) building data centers in Ireland and Denmark in its biggest European investment, with the facilities set to run services such as iTunes and maps for users of its devices.

NVIDIA today announced the completion of its acquisition of Mellanox Technologies, Ltd., for a transaction value of $7 billion. The acquisition, initially...

ABSTRACT

Human adenoviruses (HAdVs) have developed mechanisms to manipulate cellular antiviral measures to ensure proper DNA replication, with detailed processes far from being understood. Host cells repress incoming viral genomes through a network of transcriptional regulators that normally control cellular homeostasis. The nuclear domains involved are promyelocytic leukemia protein nuclear bodies (PML-NBs), interferon-inducible, dot-like nuclear structures and hot spots of SUMO posttranslational modification (PTM). In HAdV-infected cells, such SUMO factories are found in close proximity to newly established viral replication centers (RCs) marked by the adenoviral DNA binding protein (DBP) E2A. Here, we show that E2A is a novel target of host SUMOylation, leading to PTMs supporting E2A function in promoting productive infection. Our data show that SUMOylated E2A interacts with PML. Decreasing SUMO-E2A protein levels by generating HAdV variants mutated in the three main SUMO conjugation motifs (SCMs) led to lower numbers of viral RCs and PML-NBs, and these two structures were no longer next to each other. Our data further indicate that SUMOylated E2A binds the host transcription factor Sp100A, promoting HAdV gene expression, and represents the molecular bridge between PML tracks and adjacent viral RCs. Consequently, E2A SCM mutations repressed late viral gene expression and progeny production. These data highlight a novel mechanism used by the virus to benefit from host antiviral responses by exploiting the cellular SUMO conjugation machinery.

IMPORTANCE PML nuclear bodies (PML-NBs) are implicated in general antiviral defense based on recruiting host restriction factors; however, it is not understood so far why viruses would establish viral replication centers (RCs) juxtaposed to such "antiviral" compartments. To understand this enigma, we investigate the cross talk between PML-NB components and viral RCs to find the missing link connecting both compartments to promote efficient viral replication and gene expression. Taken together, the current concept is more intricate than originally believed, since viruses apparently take advantage of several specific PML-NB-associated proteins to promote productive infection. Simultaneously, they efficiently inhibit antiviral measures to maintain the viral infectious program. Our data provide evidence that SUMOylation of the viral RC marker protein E2A represents the basis of this virus-host interface and regulates various downstream events to support HAdV productive infection. These results are the basis of our current attempts to generate and screen for specific E2A SUMOylation inhibitors to constitute novel therapeutic approaches to limit and prevent HAdV-mediated diseases and mortality of immunosuppressed patients.

The overlooked epicenter of the Covid-19 pandemic is our nation's nursing homes, veterans' homes, and other long-term care facilities.

Andrea Arroyo

The post The Pandemic’s Impact on Immigration Detention Centers appeared first on The Nation.

While Americans are sheltering in place, the federal government is shuffling hundreds of immigrant detainees between U.S. towns, putting vulnerable communities at risk.

Regency Nursing and Rehabilitation Centers Inc. nursing home chain will pay the United States $4 million to settle allegations that Regency submitted false claims to Medicare and the Texas Medicaid program. The Victoria, Texas-based chain currently owns and operates 24 nursing home facilities located through the state.

"For more than a century, UNCA has worked to improve conditions in distressed neighborhoods and restore opportunity to those who live there," said Acting Associate Attorney General West.

The owner of several Detroit-area adult day care centers pleaded guilty today for her role in a $13.2 million psychotherapy fraud scheme.

The owner of several Detroit-area businesses that housed severely mentally-disabled Medicare recipients pleaded guilty today for his role in a $13.2 million fraud scheme.

Dr. Farid Fata, 48, of Oakland Township, Michigan, was arrested this morning and charged in a criminal complaint for his role in a health care fraud scheme which involved submitting false claims to Medicare for services that were medically unnecessary, including chemotherapy treatments.

A federal jury in Detroit today convicted the owner and the program coordinator of two Flint, Mich., adult day care centers for their participation in a $3.2 million Medicare fraud scheme.

A grand jury in Miami, Florida, indicted two individuals and two corporations for allegedly operating call centers in Peru that lied to and threatened Spanish-speaking victims into paying fraudulent settlements.

McKesson Corporation has agreed to pay $18 million to resolve allegations that it improperly set temperature monitors used in shipping vaccines under its contract with the Centers for Disease Control and Prevention (CDC), the Justice Department announced today. McKesson is a pharmaceutical distributor with corporate headquarters in San Francisco

"For the US in 2006, online data centres accounted for 1.5 percent of the entire country's electricity use - equating to more than the entire state of Massachusetts. " View the chart up close...Really interesting facts/stats! Image via GDS Digital via

We have long called for deposits on everything. California shows that even that is not enough.

The tech giant just agreed to purchase all of the energy from GE's Tullahennel wind farm.

Floors and furniture in most daycare centers are being mopped and cleaned constantly to protect kids from infections. But, frequently getting exposed

Transplant centers are declining viable kidneys on behalf of patients whose lives might have been saved by the organs, reports a new study. The findings

A tool to assess organ acceptance practices by transplant centers found wide variability in centers' willingness to use less-than-ideal donor kidneys has been developed by researchers.

Google’s data centers run 24/7 and suck up a ton of energy — so it’s in both the company’s and the planet’s interest to make them do so as efficiently as possible. One new method has the facilities keeping an eye on the weather so they know when the best times are to switch to […]

The New York Civil Liberties Union has filed a lawsuit against ICE claiming New York officers rigged algorithms to always recommend people arrested for immigration violations be detained.