ic Synthesis, evaluation and molecular modelling of piceatannol analogues as arginase inhibitors By feeds.rsc.org Published On :: RSC Med. Chem., 2020, Advance ArticleDOI: 10.1039/D0MD00011F, Research ArticleJ. Muller, B. Cardey, A. Zedet, C. Desingle, M. Grzybowski, P. Pomper, S. Foley, D. Harakat, C. Ramseyer, C. Girard, M. PudloA quantum chemistry guided optimisation (leading to piceatannol analogue 3t) with a good understanding of the catechol binding mode to the bimanganese cluster of arginase.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ic Discovery, SAR study and ADME properties of methyl 4-amino-3-cyano-1-(2-benzyloxyphenyl)-1H-pyrazole-5-carboxylate as an HIV-1 replication inhibitor By feeds.rsc.org Published On :: RSC Med. Chem., 2020, Advance ArticleDOI: 10.1039/D0MD00025F, Research ArticleJeanne Fichez, Cathia Soulie, Laurent Le Corre, Sophie Sayon, Stéphane Priet, Karine Alvarez, Olivier Delelis, Patrick Gizzi, Guillaume Prestat, Christine Gravier-Pelletier, Anne-Geneviève Marcelin, Vincent Calvez, Patricia BuscaIdentified as an HIV-1 inhibitor in cellulo, this pyrazole does not belong to the three main classes of anti HIV-drugs, a feature of prime interest in the context of viral resistance.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ic Cyclic boronates as versatile scaffolds for KPC-2 β-lactamase inhibition By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,491-496DOI: 10.1039/C9MD00557A, Research ArticleCatherine L. Tooke, Philip Hinchliffe, Alen Krajnc, Adrian J. Mulholland, Jürgen Brem, Christopher J. Schofield, James SpencerMono- (vaborbactam) and bi-cyclic (taniborbactam) boronate inhibitors bind KPC-2 similarly, but the latter is essentially irreversible.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ic A promising anticancer drug: a photosensitizer based on the porphyrin skeleton By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,427-437DOI: 10.1039/C9MD00558G, Review ArticleQizhi Zhang, Jun He, Wenmei Yu, Yanchun Li, Zhenhua Liu, Binning Zhou, Yunmei LiuThis article reviews the research status of porphyrin photosensitizers; future perspectives and current challenges are discussed.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ic Unveiling the active isomer of cycloalanopine, a cyclic opine from Lactobacillus rhamnosus LS8, through synthesis and analog production By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,528-531DOI: 10.1039/D0MD00033G, Research ArticleIsaac Antwi, Sorina Chiorean, Marco J. van Belkum, John C. VederasStereochemistry of the antimicrobial isomer of a cyclic opine was determined by synthesis using oxidative cyclisation of a bis-hydrazide.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ic Albon denies Leclerc a virtual F1 'trick By www.rediff.com Published On :: The Thai's victory over his Ferrari rival gave Red Bull something to celebrate on a day that should have seen the return of Max Verstappen's home Dutch Grand Prix after a 35-year absence. Full Article
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