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Fire Prevention Month 2024

As Fire Prevention Month begins, the Delaware State Fire Marshal’s Office urges Delawareans to make sure their smoke alarms are working. The theme for Fire Prevention Week, October 6-12, 2024 is “Smoke alarms: Make them work for you!”. According to NFPA, smoke alarms reduce the risk of dying in a home fire by more than […]




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SAS Customer Intelligence 360: Behavioral event tracking, targeting & engagement analysis

There's no question that we're all increasingly, and often exclusively, interacting with brands digitally. Consumers are now online through countless mechanisms – from laptops and mobile apps to AI-enabled voice assistants and sensor-based wearables. Engagement is diversifying in fascinating new ways. And when organizations can't see their customers interacting in [...]

SAS Customer Intelligence 360: Behavioral event tracking, targeting & engagement analysis was published on Customer Intelligence Blog.




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Prevent routing on adjacent layers without affecting pour

Hello,

I have a sensitive trace on layer 2 and I would like to prevent any routing along or across it on adjacent layers (L1 and L3).

My idea was to use a route keepout shape on L1 and L3, however that also removed the ground pour on those layers and I would like to keep the ground pour.

Can I get around this somehow or should I use something else than route keepout?

Regards,

Filip




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Tourism Research Australia to report vital business events data

Tourism Research Australia will start collecting data on business events to measure industry performance and help inform decision making.



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US Government Officials Affirm US Commitment to Pacific Islands at East-West Center Event

US Government Officials Affirm US Commitment to Pacific Islands at East-West Center Event US Government Officials Affirm US Commitment to Pacific Islands at East-West Center Event
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East-West Center Hosts Launch Event Featuring US and Mekong Region Government Officials for New Report on Transboundary River Governance

East-West Center Hosts Launch Event Featuring US and Mekong Region Government Officials for New Report on Transboundary River Governance East-West Center Hosts Launch Event Featuring US and Mekong Region Government Officials for New Report on Transboundary River Governance
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The Next Event on God’s Prophetic Timetable (1 Thessalonians 4:13-18)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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The Next Event on God’s Prophetic Timetable, Part 2 (1 Thessalonians 4:13-18)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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Thinking Biblically About Current Events: A Conversation with John MacArthur (Selected Scriptures)

Check here each week to keep up with the latest from John MacArthur's pulpit at Grace Community Church.




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Forest Fires—Indonesian Experience Highlights Prevention Challenges

Forest Fires—Indonesian Experience Highlights Prevention Challenges Forest Fires—Indonesian Experience Highlights Prevention Challenges
Anonymous (not verified) Fri, 09/11/2020 - 13:50

East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

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East-West Wire

Tagline
News, Commentary, and Analysis
East-West Wire

The East-West Wire is a news, commentary, and analysis service provided by the East-West Center in Honolulu. Any part or all of the Wire content may be used by media with attribution to the East-West Center or the person quoted. To receive East-West Center Wire media releases via email, subscribe here.

For links to all East-West Center media programs, fellowships and services, see www.eastwestcenter.org/journalists.

Explore




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Catherine, Princess of Wales will attend Remembrance events in London over the weekend




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EU Green Diplomacy Weeks in ASEAN 2024 kicks off with a fun run and green events

Around 500 participants took part, including representatives from ASEAN, the EU and its Member States, youth and individuals with special needs. The event took place along Jalan Sudirman, leading to Gelora Bung Karno, Senayan, Jakarta.




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Israeli NGO hosts event for fallen immigrant soldiers, security personnel in Middle East war


During the event, an exhibition presented the fallen soldiers and presented their personal stories, and a ceremony was held in their memory with the participation of the bereaved families.




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Queen Camilla makes first statement after missing key royal event

Queen Camilla makes first statement after missing key royal eventQueen Camilla marked her comeback to royal duties after she was forced to miss an important event on the royal calendar on doctor’s advice.A week after palace had cancelled her scheduled engagements, Camilla on Tuesday attended...




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Innovative Finance Facility for Climate in Asia and the Pacific Kick-Off Event - Masatsugu Asakawa

Remarks by Masatsugu Asakawa, President, Asian Development Bank, at the Innovative Finance Facility for Climate in Asia and the Pacific Kick-Off Event, 12 November 2024




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Asian Development Blog: How Strengthened Regulations and Healthcare Can Prevent Lead Poisoning

Lead exposure remains a significant public health threat in Asia and the Pacific, especially in low- and middle-income countries. The global effort to address lead poisoning must focus on stricter regulations, enhanced healthcare capacity, and coordinated international action to protect vulnerable populations.




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Strengthening Country Systems for Prevention and Response to Gender-Based Violence

The proposed project will support the Royal Government of Cambodia in its commitment to reduce Gender-based Violence (GBV) line with Sustainable Development Goal (SDG) 5 on gender equality, specifically to eliminate all forms of violence against all women and girls in the public and private spheres, through proven and novel approaches across the continuum of prevention, mitigation, and response.




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New anti-ageing vaccines promise to prevent diseases like Alzheimer's

It may soon be possible to vaccinate ourselves against the diseases of old age, keeping our body and brain healthier for longer




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You can turn any random sequence of events into a clock

A set of mathematical equations can help turn apparently random observations into a clock – and then measure its accuracy




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Chris Packham: We're precipitating a mass extermination event

Chris Packham's new BBC series, Earth, looks at significant moments in Earth's history, including anthropogenic climate change and biodiversity loss, "It's not a sixth mass extinction event that we're precipitating," he says, "it's a mass extermination event"




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Health Tip: Help Prevent a Herniated Disk

Title: Health Tip: Help Prevent a Herniated Disk
Category: Health News
Created: 8/29/2008 2:00:00 AM
Last Editorial Review: 8/29/2008 12:00:00 AM




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Health Tip: Help Prevent Bloating

Title: Health Tip: Help Prevent Bloating
Category: Health News
Created: 8/23/2010 10:10:00 AM
Last Editorial Review: 8/24/2010 12:00:00 AM




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New Blood Thinner Effient No Better Than Plavix at Preventing Heart Trouble: Study

Title: New Blood Thinner Effient No Better Than Plavix at Preventing Heart Trouble: Study
Category: Health News
Created: 8/26/2012 10:05:00 AM
Last Editorial Review: 8/27/2012 12:00:00 AM




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Health Tip: Help Prevent a Poison Ivy Rash

Title: Health Tip: Help Prevent a Poison Ivy Rash
Category: Health News
Created: 8/28/2012 8:05:00 AM
Last Editorial Review: 8/28/2012 12:00:00 AM




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2 Common Blood Pressure Meds Fare Equally in Preventing Heart Woes

Title: 2 Common Blood Pressure Meds Fare Equally in Preventing Heart Woes
Category: Health News
Created: 8/27/2012 6:05:00 PM
Last Editorial Review: 8/28/2012 12:00:00 AM




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Antiviral Drug May Prevent Ebola, Small Study Suggests

Title: Antiviral Drug May Prevent Ebola, Small Study Suggests
Category: Health News
Created: 8/25/2015 12:00:00 AM
Last Editorial Review: 8/26/2015 12:00:00 AM




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Fast Action Can Prevent Sepsis Death: CDC

Title: Fast Action Can Prevent Sepsis Death: CDC
Category: Health News
Created: 8/23/2016 12:00:00 AM
Last Editorial Review: 8/24/2016 12:00:00 AM




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Aspirin, Fish Oil May Not Prevent Heart Trouble in Those Already at Risk

Title: Aspirin, Fish Oil May Not Prevent Heart Trouble in Those Already at Risk
Category: Health News
Created: 8/27/2018 12:00:00 AM
Last Editorial Review: 8/28/2018 12:00:00 AM




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Health Tip: Pool Fencing Helps Prevent Drowning

Title: Health Tip: Pool Fencing Helps Prevent Drowning
Category: Health News
Created: 8/29/2018 12:00:00 AM
Last Editorial Review: 8/29/2018 12:00:00 AM




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What Treatments Work Best to Prevent Suicide?

Title: What Treatments Work Best to Prevent Suicide?
Category: Health News
Created: 8/27/2019 12:00:00 AM
Last Editorial Review: 8/27/2019 12:00:00 AM




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Health Tip: Preventing Kidney Stones

Title: Health Tip: Preventing Kidney Stones
Category: Health News
Created: 8/30/2019 12:00:00 AM
Last Editorial Review: 8/30/2019 12:00:00 AM




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Kids in Hot Cars: How to Prevent Heatstroke Deaths

Title: Kids in Hot Cars: How to Prevent Heatstroke Deaths
Category: Health News
Created: 8/29/2019 12:00:00 AM
Last Editorial Review: 8/30/2019 12:00:00 AM




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'Vacation PrEP': Short-Term HIV Prevention a Viable Option

Title: 'Vacation PrEP': Short-Term HIV Prevention a Viable Option
Category: Health News
Created: 8/27/2020 12:00:00 AM
Last Editorial Review: 8/28/2020 12:00:00 AM




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KLS-13019, a Novel Structural Analogue of Cannabidiol and GPR55 Receptor Antagonist, Prevents and Reverses Chemotherapy-Induced Peripheral Neuropathy in Rats [Special Section: Cannabinoid Signaling in Human Health and Disease]

Neuropathic pain is a form of chronic pain that develops because of damage to the nervous system. Treatment of neuropathic pain is often incompletely effective, and most available therapeutics have only moderate efficacy and present side effects that limit their use. Opioids are commonly prescribed for the management of neuropathic pain despite equivocal results in clinical studies and significant abuse potential. Thus, neuropathic pain represents an area of critical unmet medical need, and novel classes of therapeutics with improved efficacy and safety profiles are urgently needed. The cannabidiol structural analog and novel antagonist of GPR55, KLS-13019, was screened in rat models of neuropathic pain. Tactile sensitivity associated with chemotherapy exposure was induced in rats with once-daily 1-mg/kg paclitaxel injections for 4 days or 5 mg/kg oxaliplatin every third day for 1 week. Rats were then administered KLS-13019 or comparator drugs on day 7 in an acute dosing paradigm or days 7–10 in a chronic dosing paradigm, and mechanical or cold allodynia was assessed. Allodynia was reversed in a dose-dependent manner in the rats treated with KLS-13019, with the highest dose reverting the response to prepaclitaxel injection baseline levels with both intraperitoneal and oral administration after acute dosing. In the chronic dosing paradigm, four consecutive doses of KLS-13019 completely reversed allodynia for the duration of the phenotype in control animals. Additionally, coadministration of KLS-13019 with paclitaxel prevented the allodynic phenotype from developing. Together, these data suggest that KLS-13019 represents a potential new drug for the treatment of neuropathic pain.

SIGNIFICANCE STATEMENT

Chemotherapy-induced peripheral neuropathy (CIPN) is a common, debilitating side effect of cancer treatment with no known cure. The GPR55 antagonist KLS-13019 represents a novel class of drug for this condition that is a potent, durable inhibitor of allodynia associated with CIPN in rats in both prevention and reversal-dosing paradigms. This novel therapeutic approach addresses a critical area of unmet medical need.




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Seventy-Five Years of Interactions: The Department of Physiology and Pharmacology at Karolinska Institutet and Pharmacological Reviews [75th Anniversary Celebration Collection Special Section-Editorial]




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CGRP therapy in primary care for migraine: prevention and acute medication




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[PERSPECTIVES] Restoration of Rod-Derived Metabolic and Redox Signaling to Prevent Blindness

Vision is initiated by capturing photons in highly specialized sensory cilia known as the photoreceptor outer segment. Because of its lipid and protein composition, the outer segments are prone to photo-oxidation, requiring photoreceptors to have robust antioxidant defenses and high metabolic synthesis rates to regenerate the outer segments every 10 days. Both processes required high levels of glucose uptake and utilization. Retinitis pigmentosa is a prevalent form of inherited retinal degeneration characterized by initial loss of low-light vision caused by the death of rod photoreceptors. In this disease, rods die as a direct effect of an inherited mutation. Following the loss of rods, cones eventually degenerate, resulting in complete blindness. The progression of vision loss in retinitis pigmentosa suggested that rod photoreceptors were necessary to maintain healthy cones. We identified a protein secreted by rods that functions to promote cone survival, and we named it rod-derived cone viability factor (RdCVF). RdCVF is encoded by an alternative splice product of the nucleoredoxin-like 1 (NXNL1) gene, and RdCVF was found to accelerate the uptake of glucose by cones. Without RdCVF, cones eventually die because of compromised glucose uptake and utilization. The NXNL1 gene also encodes for the thioredoxin RdCVFL, which reduces cysteines in photoreceptor proteins that are oxidized, providing a defense against radical oxygen species. We will review here the main steps of discovering this novel intercellular signaling currently under translation as a broad-spectrum treatment for retinitis pigmentosa.




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Ronnie O'Sullivan leads stellar line-up for new snooker events in major shake-up



Ronnie O'Sullivan has agreed to compete in new snooker events.




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Emma Raducanu adds event to schedule after Wimbledon talks as financial boost secured



Emma Raducanu struck a deal to return to one of her favourite tournaments.




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Great British summer of sport - your guide to how each event is ready for return of crowds





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Which sporting events are off this weekend following the Queen's death?



  • topics:events/premier-league
  • topics:events/football-championship
  • topics:organisations/the-football-association
  • topics:organisations/england-and-wales-cricket-board
  • structure:sport
  • storytype:standard



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Crocodiles baited with 'nausea-inducing chemical' to prevent them from eating toxic, invasive toad

Scientists in Australia are boosting the country's dwindling freshwater crocodile numbers by getting the animals to stop eating a poisonous toad.



  • 4e478891-8905-5294-9d5a-f9b830d2a121
  • fnc
  • Fox News
  • fox-news/science
  • fox-news/world/world-regions/australia
  • fox-news/science/wild-nature/reptiles
  • fox-news/science
  • article

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Voyager 2’s Flyby of Uranus in 1986 was During Anomalous Solar Event, New Study Suggests

When NASA’s Voyager 2 spacecraft flew by Uranus in 1986, it provided scientists’ first close glimpse of this ice-giant planet.

The post Voyager 2’s Flyby of Uranus in 1986 was During Anomalous Solar Event, New Study Suggests appeared first on Sci.News: Breaking Science News.




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Parkrun events could boost your life satisfaction

People report greater life satisfaction six months after starting Parkrun events, which could partly be due to the supportive environment




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Comment on Preventing Hair Loss: How Diwali Commitments Disrupt Women’s Hair Care Routine by Emlakçılık Belgesi

https://maps.google.co.in/url?q=https://yukselenakademi.com/kurs/detay/emlakcilik-belgesi-seviye-5





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4 Creative Ways to Keep Guests Engaged at Your Next Business Event

Organizing business events can be a challenge. There’s always the concern that guests will lose interest or become disengaged. When organizing team-building activities and office parties, it becomes essential to add something extra that keeps everyone active and involved. That way, the event not only meets expectations but exceeds them, leaving people excited and talking […]

The post 4 Creative Ways to Keep Guests Engaged at Your Next Business Event appeared first on Chart Attack.