Synaccess netBooter NP-02x and NP-08x version 6.8 suffer from an authentication bypass vulnerability due to a missing control check when calling the webNewAcct.cgi script while creating users. This allows an unauthenticated attacker to create an admin user account and bypass authentication giving her the power to turn off a power supply to a resource.

A new report produced by the International Energy Agency (IEA), the International Renewable Energy Agency (IRENA), the United Nations Statistics Division (UNSD), the World Bank and the World Health Organization (WHO) and released this week says that despite significant progress in recent years, the world is falling short of meeting the global energy targets set in the United Nations Sustainable Development Goals (SDG) for 2030.

Kyushu Electric Power Co. will suspend responding to applications from renewable-energy producers applying to access its grid while it reviews how much more clean energy it’s capable of handling.

New Crane Wharf Freehold Ltd v Jonathan Mark Dovener [2019] UKUT 98 (LC) A lease covenant requiring the tenant defendant, Mr Dovener, to “permit” its landlord “…at al...

Executive Summary The European Commission has consulted on an implementing regulation which will provide additional detail for procedures and criteria to be followed by service facility operators in order to satisfy their obligations under Directive...

The Hong Kong Court has recently confirmed the Securities and Futures Commission (“SFC”)’s powers to seize, search and compel access to digital devices rejecting challenges to such powers based on privacy grounds. Data privacy is a...

(MENAFN - IANS) San Francisco, May 9 (IANS) Taking control of a Microsoft employee's GitHub account, a hacker recently got access to some of the c... ......

Press freedom in Bangladesh has been in decline long before the coronavirus came to our shores. Over the last decade, thanks to increasingly repressive media laws and highhanded measures adopted by the authorities, the health of journalism has been deteriorating in such a way that even the stalwarts of the fourth estate began to worry […]

The post Blocking media access during Covid-19 appeared first on Inter Press Service.

Universal health coverage must be high quality to improve patients’ health outcomes

Microchip Unveils Family Details and Opens Early Access Program for RISC-V Enabled Low-Power PolarFire SoC FPGA Family

Functional Safety Manual and FMEDA Access for dsPIC33C Family

Approved project 53097-002 in Papua New Guinea.

U.S. luxury department store chain Neiman Marcus Group said on Friday it received court approval to access $675 million of its debtor-in-possession financing, which will allow continuity of the company's business during Chapter 11 bankruptcy proceedings and enable it to pay employees and vendors.

U.S. luxury department store chain Neiman Marcus Group said on Friday it received court approval to access $675 million of its debtor-in-possession financing, which will allow continuity of the company's business during Chapter 11 bankruptcy proceedings and enable it to pay employees and vendors.

Title: CDC: Kids Lack Access to Healthy Food Choices
Category: Health News
Created: 4/27/2011 11:00:00 AM
Last Editorial Review: 4/27/2011 12:00:00 AM

Title: White House to Challenge Ruling on Unlimited Access to 'Morning-After' Pill
Category: Health News
Created: 5/2/2013 10:35:00 AM
Last Editorial Review: 5/2/2013 12:00:00 AM

Title: Study Supports Broader Access to Lap-Band Weight-Loss Surgery
Category: Health News
Created: 5/2/2013 10:35:00 AM
Last Editorial Review: 5/2/2013 12:00:00 AM

A new page, Public Access & PMC, has now been added to the About PMC section of the PubMed Central site. “Public Access & PMC” provides information on the relationship between PMC and the NIH Public Access policy, including the difference between the NIH Public Access journal list and PMC journal list. In particular, authors and publishers should find this new site to be a useful resource.

The Public Access & PMC page has been redesigned for greater clarity and usability. In addition to including a list of the FAQs at the top, the new page features a table illustrating all the ways to find various reference numbers for an article: the PMID, NIHMSID, and most important, the PMCID, which must be used to demonstrate compliance in terms of the NIH Public Access Policy.

You can now search for Open Access articles that have certain types of licenses, by using special filters in both PMC and PubMed. These filters are based on license information that is provided to PMC by publishers and other content providers, as encoded by machine-readable identifiers in the source XML of each article. For more information, see our updated Open Access Subset page.

Last month marked the third anniversary of the White House’s Office of Science and Technology Policy (OSTP) memorandum directing Federal agencies with more than $100 million in annual research and development (R&D) expenditures to develop plans for increasing public access to the results of the research they support, including scholarly publications. As a result of this directive, in 2015, PMC started providing support as a public access repository for funding agencies beyond the National Institutes of Health (NIH) and Howard Hughes Medical Institute (HHMI).

As of March 2015, the following additional agencies are using the NIH Manuscript Submission (NIHMS) system to facilitate the deposit in PMC of peer-reviewed manuscripts that fall under their public access policies:

• Agency for Healthcare Research Quality (AHRQ/HHS)
• Centers for Disease Control and Prevention (CDC/HHS),
• Food and Drug Administration (FDA/HHS),
• National Institute of Standards and Technology (NIST), and
• U.S. Department of Veterans Affairs (VA)

Additionally, the following additional HHS and other federal agencies have announced public access plans and committed to using PMC as the repository for agency-funded publications:

• Administration for Community Living (ACL/HHS)
• Assistant Secretary for Preparedness and Response (ASPR/HHS)
• Environmental Protection Agency (EPA)
• National Aeronautics and Space Administration (NASA)

PMC will continue to update the list of participating funding agencies at Public Access and PMC as these agencies begin implementation of their policies.

More information about the current status of public access expansion as a result of the OSTP memo can be found on the White House blog.

PMC has reorganized its FTP Service site for users interested in accessing the Text Mining Collections, which include the original Open Access (OA) Subset. New top-level FTP directories help users quickly locate the content available for bulk download that best suits their research needs. These directories include:

• oa_package - article packages for individual OA articles
• oa_pdf – individual PDFs for OA articles
• oa_bulk – bulk packages of text from OA articles
• manuscript – author manuscripts collected under a funding agency’s public access policy
• historical_ocr – select OCR texts from the PMC Back Issue Digitization project

To make it easier for users to identify and comply with the different licenses that apply to OA articles, new file lists have been created and the file lists for individual OA articles now include a “license-type” field for each article. Similarly, the bulk packages of OA article text have been divided into two sets. One set comprises articles that may be used for commercial purposes (the Commercial Use Collection); the other contains articles that can be used only for non-commercial purposes. See the Open Access Subset page for details.

To allow regular users to transition to the new arrangement, the previous arrangement of files and directories will be maintained in parallel for at least four weeks (i.e., until the end of August 2016).

Collaboration with publishers and funders to ensure the openness and preservation of the scientific record is one of PMC’s core principles. Open Access Week offers an opportunity to celebrate some of the recent outcomes of these collaborations:

• In July 2018, the PMC corpus of publicly accessible articles hit 5 million articles.
• In May 2018, the PMC Open Access Subset surpassed the 2 million article mark.
• The Author Manuscript Collection now includes more than 500,000 papers for text mining.
• The PMC and Research Funder Policy page underwent an update in September 2018 to increase transparency around funder support in PMC for publishers, authors, and the public.
• Funder policy support in PMC has been extended to the US Department of Homeland Security, in addition to several new US private research funders via the Health Research Alliance.

In FY2018 more than 200 new journals committed to archiving their complete contents in PMC, to be made publicly accessible in 12 months or less.

On March 18, 2019, PMC will no longer provide bulk packages of Open Access (OA) Subset text and XML at the top level directory of the FTP Service. These files were superseded in August 2016 by the Commercial Use and Non-Commercial Use bulk packages located in the oa_bulk subdirectory. One set comprises articles that may be used for commercial purposes (the Commercial Use Collection); the other contains articles that can be used only for non-commercial purposes. Anyone planning to use OA subset content for non-commercial purposes will need to download both “non_comm_use.*.tar.gz” and “comm_use.*.tar.gz” to access the complete collection. See the Open Access Subset page for additional details. Questions should be directed to pubmedcentral@ncbi.nlm.nih.gov.

ABSTRACT

Human immunodeficiency virus type 1 (HIV-1) establishes lifelong infections in humans, a process that relies on its ability to thwart innate and adaptive immune defenses of the host. Recently, we reported that HIV-1 infection results in a dramatic reduction of the cellular peroxisome pool. Peroxisomes are metabolic organelles that also function as signaling platforms in the innate immune response. Here, we show that the HIV-1 accessory protein Vpu is necessary and sufficient for the depletion of cellular peroxisomes during infection. Vpu induces the expression of four microRNAs that target mRNAs encoding proteins required for peroxisome formation and metabolic function. The ability of Vpu to downregulate peroxisomes was found to be dependent upon the Wnt/β-catenin signaling pathway. Given the importance of peroxisomes in innate immune signaling and central nervous system function, the roles of Vpu in dampening antiviral signaling appear to be more diverse than previously realized. Finally, our findings highlight a potential role for Wnt/β-catenin signaling in peroxisome homeostasis through modulating the production of biogenesis factors.

IMPORTANCE People living with HIV can experience accelerated aging and the development of neurological disorders. Recently, we reported that HIV-1 infection results in a dramatic loss of peroxisomes in macrophages and brain tissue. This is significant because (i) peroxisomes are important for the innate immune response and (ii) loss of peroxisome function is associated with cellular aging and neurodegeneration. Accordingly, understanding how HIV-1 infection causes peroxisome depletion may provide clues regarding how the virus establishes persistent infections and, potentially, the development of neurological disorders. Here, we show that the accessory protein Vpu is necessary and sufficient for the induction of microRNAs that target peroxisome biogenesis factors. The ability of Vpu to downregulate peroxisome formation depends on the Wnt/β-catenin pathway. Thus, in addition to revealing a novel mechanism by which HIV-1 uses intracellular signaling pathways to target antiviral signaling platforms (peroxisomes), we have uncovered a previously unknown link between the Wnt/β-catenin pathway and peroxisome homeostasis.

To better the health of all North Carolinians, policymakers must come together to improve access to care, expand broadband, and close the coverage gap.

A time course experiment is a widely used design in the study of cellular processes such as differentiation or response to stimuli. In this paper, we propose time course regulatory analysis (TimeReg) as a method for the analysis of gene regulatory networks based on paired gene expression and chromatin accessibility data from a time course. TimeReg can be used to prioritize regulatory elements, to extract core regulatory modules at each time point, to identify key regulators driving changes of the cellular state, and to causally connect the modules across different time points. We applied the method to analyze paired chromatin accessibility and gene expression data from a retinoic acid (RA)–induced mouse embryonic stem cells (mESCs) differentiation experiment. The analysis identified 57,048 novel regulatory elements regulating cerebellar development, synapse assembly, and hindbrain morphogenesis, which substantially extended our knowledge of cis-regulatory elements during differentiation. Using single-cell RNA-seq data, we showed that the core regulatory modules can reflect the properties of different subpopulations of cells. Finally, the driver regulators are shown to be important in clarifying the relations between modules across adjacent time points. As a second example, our method on Ascl1-induced direct reprogramming from fibroblast to neuron time course data identified Id1/2 as driver regulators of early stage of reprogramming.

Editor’s Note: This article is adapted from a speech Ms. Youssef delivered as President, Health Care & Education of the American Diabetes Association at its 79th Scientific Sessions in San Francisco, CA, on 8 June 2019. A webcast of the speech can be viewed on ADA’s DiabetesPro website at professional.diabetes.org/webcast/president-health-care-education-address%E2%80%94it%E2%80%99s-all-about-access.

Background

Advances in information communications technology (ICT) provide opportunities for enhanced diabetes care. Knowledge of the more acceptable communication modalities in patients of different ages will help to inform the direction of future innovations.

Background:

It is unclear how patient-reported access to primary care differs by physician payment model and participation in team-based care. We examined the association between timely and after-hours access to primary care and physician payment model and participation in team-based care, and sought to assess how access varied by patient characteristics.

This example demonstrates customizations that enable keyboard shortcuts and an experimental Voice Assistant to improve the accessible of Interactive Video. Action Shortcut Navigate through annotations […]

The post Accessibility appeared first on e-Learning Feeds.

Developer Mirari & Co. announced the science-fiction action platformer Dark Light for Windows PC via Steam Early Access on May 8 and later for the Nintendo Switch when the game leaves Steam Early Access. 

Mirari & Co. is looking to release the game within one year of the Steam Early Access release, however, it depends "on how we are taking players suggestions and advice to shaping the game."

View the latest trailer of the game below:

Here is an overview of the game:

Dark Light is a science-fiction action-platformer with unique gameplay. Explore an apocalyptic cyberpunk world full of supernatural beings. Encounter and defeat creatures of darkness invisible to the naked eye, detected only with the light source from your drone. Experience the horror and feel their presence as they surround you.

As a Dark Hunter you were dropped into a wreaked world. To survive, you need to equip yourself, fight your way through, and collect ‘shards’ from killing supernatural creatures to reinforce your energy. Through survival, you will explore the mysterious dark zones of the apocalypse world.

Key Features:

• Cinematic quality graphic, detailed characters and environment design, and vivid animation with lush visual effect.
• A variety of range, melee, and throwable weapons; unique items; and multiple ways to upgrade weapons, special equipment, and the player to shape your own character skills.
• Non-linear map structure for you to choose your own path to explore the dark zones. Encounter horrifying supernatural enemies, fearsome bosses, and friendly NPCs, and fight with invisible creatures that can only be seen in a special light source.
• Detect invisible enemies and reveal hidden paths with the special light source from your drone.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443411/sci-fi-action-platformer-dark-light-launches-may-8-for-steam-early-access-later-for-switch/

We are increasingly aware that our personal data is a valuable commodity – but just how valuable? A survey has revealed how much people are willing to sell their data for

Chief Justice John Roberts on Friday put a temporary hold on the release of secret materials from former special counsel Robert Mueller's investigation to a Democrat-led House committee.

The order stops the clock on a lower court's ruling requiring the Justice Department to turn over confidential grand jury materials underlying ...

It’s one of the only incubators focused on solar companies – but Powerhouse is part of a larger movement to nurture new companies in the low-carbon future

It started with a crowdfunding startup, an investment from Prince, and the idea to help new solar companies tackle business challenges that can be hard to overcome on their own.

Now, four years later, the idea has morphed into a group called Powerhouse, and notably, in a world flush with tech startups, it’s one of the only incubators out there focused on launching and growing solar companies.

U.S. luxury department store chain Neiman Marcus Group said on Friday it received court approval to access $675 million of its debtor-in-possession financing, which will allow continuity of the company's business during Chapter 11 bankruptcy proceedings and enable it to pay employees and vendors.

Here are the Government guidelines on how the furlough scheme portal works

Twitter is down for a large number of users leaving them unable to load posts.

Care home workers say employers are playing "Russian roulette" with their lives as personal protective equipment (PPE) is withheld or rationed amid unclear guidance, according to a union.

Urgent action is still needed to make it easier for vulnerable people to access supermarket delivery slots and other sources of supplies, Which? has warned.

Tam Carrigan from the Haringey Play Association shares his story You can donate at virginmoneygiving.com/fund/FoodforLondonNOW

Devices will stop working for users who don't want to pay the new monthly fee.

The hacker had access to personal information, the ability to change passwords and two-factor authentication, and could steal valuable in-game items from some of the 'richest' players in the game

EA Access 12 Month Xbox One Membership Card Global $22.99

https://www.bcdkey.com/ea-access-12-month-xbox-one-membership-card-global.html

'It's inevitable many desperate patients will resort to 'DIY dentistry'

Celebrities have backed calls for Home Secretary Priti Patel to end restrictions that prevent thousands of migrants in the UK from accessing financial support during the coronavirus crisis.

There are loads of titles you didn't know were on the streaming service

‘Sophisticated’ identity theft attack leads to Australian Tax Office stopping early super withdrawals until Monday

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Allegations of identity theft involving 150 Australians have forced the government to pause the early release of superannuation, after police froze $120,000 believed to have been ripped off from retirement savings.

On Friday the assistant treasurer, Michael Sukkar, announced the Australian Tax Office would pause requests for early access of superannuation until Monday “out of an abundance of caution” to consider further anti-fraud protection.