Despite significant cuts to NASAs Planetary Science Division budget early in this decade, the space agency has made impressive progress in meeting goals outlined in the 2013-2022 planetary decadal survey by the National Academies of Sciences, Engineering, and Medicine, says a new midterm assessment from the National Academies.

Read a new Perspective on promoting transparency in scientific authorship co-authored by NAS President Marcia McNutt. Appearing in the latest issue of Proceedings of the National Academy of Sciences, the piece offers suggestions for improving how author contributions are attributed in scientific publications.

To answer significant questions about planetary systems, such as whether our solar system is a rare phenomenon or if life exists on planets other than Earth, NASA should lead a large direct imaging mission – an advanced space telescope – capable of studying Earth-like exoplanets orbiting stars similar to the sun, says a new congressionally mandated report by the National Academies of Sciences, Engineering, and Medicine.

To advance the search for life in the universe, NASA should support research on a broader range of biosignatures and environments, and incorporate the field of astrobiology into all stages of future exploratory missions, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

The National Academy of Sciences (NAS) announces the appointment of May R. Berenbaum as Editor-in-Chief of the Proceedings of the National Academy of Sciences (PNAS), the official journal of the Academy. Berenbaum will begin the editorship on January 1, 2019.

We thank the organizing committee of the Second International Summit on Human Genome Editing, held this week in Hong Kong, for planning an important and timely conference on a rapidly advancing area of science and medicine.

NASA’s investment in new instruments to analyze extraterrestrial samples is insufficient to provide for replacement of existing instruments, says a new report from the National Academies of Sciences, Engineering, and Medicine.

With the new year underway, we would like to share with you our outlook for the National Academies of Sciences, Engineering, and Medicine in 2019.

Renewed interest in exploration of the moon has the potential to benefit lunar science greatly and could evolve into a program facilitated by partnerships between commercial companies and NASA’s Science Mission Directorate (SMD), say companion reports by the National Academies of Sciences, Engineering, and Medicine.

In a Nature commentary published today, National Academy of Sciences President Marcia K. McNutt and several colleagues make the case for the creation of a U.S. advisory board for research integrity and quality.

The current measles outbreaks in the United States and elsewhere are being fueled by misinformation about the safety of vaccines.

From revolutionizing cancer care to modeling the economic impact of climate change, recent winners of Nobel and Kavli Prizes have explored virtually every angle of science.

NAS President Marcia McNutt delivered the commencement address to Boston University graduates on May 19, where she discussed trust in science and evidence, and the importance of making informed decisions.

As we welcome a new year and a new decade, we can make one prediction with certainty -- profound change lies ahead.

NASA should collaborate with the Federal Aviation Administration (FAA), industry, academia to research the full effects that increased unpiloted air vehicle traffic would have on society, including ramifications to sound, privacy, environmental matters, and cybersecurity, says a new report from the National Academies of Sciences, Engineering, and Medicine.

The National Academies stand ready to convene America’s best minds in research, government, medicine, and private industry to marshal evidence-based insights and advice for confronting today’s pandemic and future crises.

In light of the present situation in the U.S., we believe that it is essential to explore a wide range of options for treating the increasing numbers of very ill patients with COVID-19 respiratory illness.

As the COVID-19 pandemic grips the nation and the world, policymakers and the public are counting on science, engineering, and medicine to discover how the virus infects humans, slow its spread, treat those infected, and provide solutions that lay the groundwork for recovery.

It is critical for the U.S. to continue its funding for the World Health Organization in the midst of the COVID-19 pandemic given the WHO’s lead role in coordinating an international response, especially in developing countries.

Anthony Fauci and other panelists explored the status of the pandemic, research underway, and the key role of vaccines in bringing the pandemic to an end.

Source: Streetwise Reports   04/22/2020

In an April 20 research note, Dawson James analyst Jason Kolbert wrote that results from Can-Fite BioPharma Ltd.'s (CANF:NYSE.MKT) Phase 2 trial of Namodenoson for nonalcoholic fatty liver disease with or without nonalcoholic steatohepatitis "look pretty good."

He added that "the consistency of the data from the studies (preclinical and clinical), should support business development interest."

Dawson James has a $9 per share target price on Can-Fite; the stock is currently trading at around $1.75 per share.

Kolbert recapped the study design and provided the results.

This purpose of this multicenter, randomized, double-blinded, placebo-controlled trial involving 60 patients was to determine dose efficacy and safety. Patients were treated twice a day with either 12.5 milligrams or 25 milligrams of oral Namodenoson or a placebo for 12 weeks.

The primary endpoint was effect on inflammation, measured by mean percent change from baseline in alanine transaminase blood levels and safety. The second endpoints included the percent change from baseline in liver fat, as determined by MRI proton density fat fraction.

In terms of safety, study participants tolerated Namodenoson at both doses, and no adverse events were reported. Otitis media occurred in two patients but was deemed to be unrelated to the drug. The four other events that occurred that were drug related were mild and self-limited.

Regarding efficacy of Namodenoson, Kolbert noted that "for a small Phase 2 exploratory study, there appears to be a significant efficacy signal."

Kolbert provided updates on other Can-Fite clinical trials.

The company's COVID-19 trial is now designed. Plans call for it to be randomized, open label, and double armed with Piclidenoson administered plus standard supportive care, compared to standard supportive care alone, in 40 hospitalized COVID-19-infected patients with moderate to severe symptomatic disease.

Patients are to be randomized at a 1:1 ratio to one of the trial arms and treated for up to four weeks. The primary efficacy measures will be time to resolution of viral shedding, time to resolution of clinical symptoms, respiratory function, need for ventilatory support and overall mortality.

Piclidenoson, Can-Fite's lead drug candidate, also is in Phase 3 in two indications: moderate to severe rheumatoid arthritis (the ACROBAT study) and moderate to severe plaque psoriasis (the COMFORT study). Enrollment for both trials is more halfway complete. In both, Piclidenoson "hold great promise as alternative therapies with what appears to be a more favorable side effects profile," Kolbert commented.

Dawson James has a Buy rating on Can-Fite BioPharma.

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Disclosures for Dawson James Securities, Can-Fite BioPharma Ltd., April 20, 2020,

Analyst Certification: The analyst(s) whose name appears on this research report certifies that 1) all of the views expressed in this report accurately reflect his (their) personal views about any and all of the subject securities or issuers discussed; and 2) no part of the research analyst’s compensation was, is, or will be directly or indirectly related to the specific recommendations or views expressed by the research analyst in this research report; and 3) all Dawson James employees, including the analyst(s) responsible for preparing this research report, may be eligible to receive non-product or service specific monetary bonus compensation that is based upon various factors, including total revenues of Dawson James and its affiliates as well as a portion of the proceeds from a broad pool of investment vehicles consisting of components of the compensation generated by investment banking activities, including but not limited to shares of stock and/or warrants, which may or may not include the securities referenced in this report.

( Companies Mentioned: CANF:NYSE.MKT, )

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NASA's Aqua satellite provided a visible image of Super Typhoon Meranti as it continued to move toward Taiwan and the northern Philippines.

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Bloomberg

If The Florist is cool and charming, its new downstairs neighbour, Las Iguanas, is all about fun and colour.

This file is in PDF format, requiring the Adobe Acrobat Reader to open.

Suggested names for the new TRAPPIST-1 system planets range from Planet McPlanetface to the series 'Friends.'

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The Kennedy Space Center hideaway sustained significant damage from Hurricane Matthew.

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Climate scientist James Hansen was arrested on Feb. 13 outside the White House while protesting the Keystone Pipeline.

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NASA astronauts make history with an all-female spacewalk — now that the spacesuit problem is resolved.