Emily J. Lombardi, Candice L. Bywater, and Craig R. White

The Oxygen and Capacity-Limited Thermal Tolerance (OCLTT) hypothesis proposes that the thermal tolerance of an animal is shaped by its capacity to deliver oxygen in relation to oxygen demand. Studies testing this hypothesis have largely focused on measuring short-term performance responses in animals under acute exposure to critical thermal maximums. The OCLTT hypothesis, however, emphasises the importance of sustained animal performance over acute tolerance. The present study tested the effect of chronic hypoxia and hyperoxia during development on medium to long-term performance indicators at temperatures spanning the optimal temperature for growth in the speckled cockroach, Nauphoeta cinerea. In contrast to the predictions of the OCLTT hypothesis, development under hypoxia did not significantly reduce growth rate or running performance, and development under hyperoxia did not significantly increase growth rate or running performance. The effect of developmental temperature and oxygen on tracheal morphology and metabolic rate were also not consistent with OCLTT predictions, suggesting that oxygen delivery capacity is not the primary driver shaping thermal tolerance in this species. Collectively, these findings suggest that the OCLTT hypothesis does not explain moderate-to-long-term thermal performance in Nauphoeta cinerea, which raises further questions about the generality of the hypothesis.

Objective

To assess the impact of APOE polymorphisms on cognitive performance in patients newly diagnosed with clinically isolated syndrome (CIS) or relapsing-remitting MS (RRMS).

Methods

This multicenter cohort study included 552 untreated patients recently diagnosed with CIS or RRMS according to the 2005 revised McDonald criteria. The single nucleotide polymorphisms rs429358 (4) and rs7412 (2) of the APOE haplotype were assessed by allelic discrimination assays. Cognitive performance was evaluated using the 3-second paced auditory serial addition test and the Multiple Sclerosis Inventory Cognition (MUSIC). Sum scores were calculated to approximate the overall cognitive performance and memory-centered cognitive functions. The impact of the APOE carrier status on cognitive performance was assessed using multiple linear regression models, also including demographic, clinical, MRI, and lifestyle factors.

Results

APOE 4 homozygosity was associated with lower overall cognitive performance, whereas no relevant association was observed for APOE 4 heterozygosity or APOE 2 carrier status. Furthermore, higher disability levels, MRI lesion load, and depressive symptoms were associated with lower cognitive performance. Patients consuming alcohol had higher test scores than patients not consuming alcohol. Female sex, lower disability, and alcohol consumption were associated with better performance in the memory-centered subtests of MUSIC, whereas no relevant association was observed for APOE carrier status.

Conclusion

Along with parameters of a higher disease burden, APOE 4 homozygosity was identified as a potential predictor of cognitive performance in this large cohort of patients with CIS and early RRMS.

Transportation infrastructure owners manage an array of different asset types such as bridges, road pavements, earthworks and drainage. Currently, most organization management procedures are siloed by asset type; however, there are important interactions between these asset groups that need to be managed in a cross-asset way. Although these interactions are known, there is little or no quantification of these interactions. For the first time, this paper quantifies that 74% of Highways England's earthwork failures are a result of drainage-related problems, either the lack of drainage infrastructure or the poor performance of it. The analysis undertaken is an important first step not only in moving towards more connected asset management planning for earthworks and drainage, but to also provide guidance for other owners of earthwork infrastructure assets to improve their strategic asset management procedures.

Thematic collection: This article is part of the Ground-related risk to transportation infrastructure collection available at https://www.lyellcollection.org/cc/Ground-related-risk-to-transportation-infrastructure

With increased interest in lipoprotein(a) (Lp[a]) concentration as a target for risk reduction and growing clinical evidence of its impact on cardiovascular disease (CVD) risk, rigorous analytical performance specifications (APS) and accuracy targets for Lp(a) are required. We investigated the biological variation (BV) of Lp(a), and 2 other major biomarkers of CVD, apolipoprotein A-I (apoA-I) and apolipoprotein B-100 (apoB), in the European Biological Variation Study population.Serum samples were drawn from 91 healthy individuals for 10 consecutive weeks at 6 European laboratories and analyzed in duplicate on a Roche Cobas 8000 c702. Outlier, homogeneity, and trend analysis were performed, followed by CV-ANOVA to determine BV estimates and their 95% CIs. These estimates were used to calculate APS and reference change values. For Lp(a), BV estimates were determined on normalized concentration quintiles.Within-subject BV estimates were significantly different between sexes for Lp(a) and between women aged <50 and >50 years for apoA-I and apoB. Lp(a) APS was constant across concentration quintiles and, overall, lower than APS based on currently published data, whereas results were similar for apoA-I and apoB.Using a fully Biological Variation Data Critical Appraisal Checklist (BIVAC)–compliant protocol, our study data confirm BV estimates of Lp(a) listed in the European Federation of Clinical Chemistry and Laboratory Medicine database and reinforce concerns expressed in recent articles regarding the suitability of older APS recommendations for Lp(a) measurements. Given the heterogeneity of Lp(a), more BIVAC-compliant studies on large numbers of individuals of different ethnic groups would be desirable.

Hundreds of neighbours came together to perform a socially distanced dance to Whigfield's iconic hit Saturday Night in an effort to spread cheer during the coronavirus lockdown.

This is the moment a firefighter's star-spangled tribute entertained health workers outside a Manhattan hospital.

Learn to get the most out of your ZFS filesystem in our new series on storage fundamentals.

Priti Patel had defended Boris Johnson after he was branded a "racist" by rapper Dave on stage at the 2020 Brit Awards.

On Thursday night, popular video game Fortnite hosted rapper Travis Scott as part of the Astronomical musical experience.

New TV drama charts story of infamous 2001 coughing scandal

Beyoncé was a surprise addition to the TV fundraiser for America's coronavirus relief effort

The singer has announced she will no longer be touring her Lover album this year

Sheen's uncanny performance got the seal of approval from the four-year-old

Taylor Swift has reignited a feud with her former record label, accusing it of "shameless greed" over a plan to release a live album she has not authorised.

For the latest episode of At Home With... pop star Justin Jesso Zooms with Amira Hashish from his family home and gives an exclusive performance of his new single

For the latest episode of At Home With...JP Saxe opens up about his song with girlfriend Julia Michaels and challenges Amira Hashish to sing her verse of If The World Was Ending

Tottenham star Heung-min Son has been awarded South Korea's Pilsung Prize after completing his military service.

Thirty-two ballerinas from 14 countries are participating.

The virtual performance includes 32 dancers in 14 countries.

A study at Columbia University Mailman School of Public Health found that black subjects who were exposed to highly segregated neighborhoods in young adulthood exhibited worse performance in cognitive skills in mid-life. This outcome may explain black-white disparities in dementia risk at older age.

Over the last twenty years, SaaS investors and executives alike have done a great job at defining, evolving and managing to Key "Enterprise Valuation" Indicators such as Customer Acquisition Cost (CAC), Customer Acquisition Cost Ratio, Customer Lifetime Value (CLTV), CMRR/ARR, Gross Margin, Gross and Net Churn, and of course, the "Rule of 40".   Several industries influencers, such as Pacific Crest (Key Bank Capital Markets), OpenView, Insight Partners and KPMG, to name just a few, have done ...

Keep on reading: SaaS Key Performance Indicator Index – An Operational Perspective

Veteran character actor Peter Gerety has a meaty role in Richard Jury's "Working Man" even as the movie shifts from quiet dignity into melodrama.

A former U.S. Department of Energy (DOE) employee who falsified his performance evaluation to justify an annual performance award to which he was not entitled pleaded guilty today to one count of making false statements.

The biotech IPO market in 2020 remains strong, despite the volatility and COVID headwinds. We’ve seen stellar pricings and good after-market performance, with ten new offerings already this year. And the queue for companies with active S1’s on file is

The post Value Creation And Destruction: Dispersion of Performance In Biotech IPOs appeared first on LifeSciVC.

The best sports nutrition formulas designed to improve performance draw from a pool of ingredients researched for benefits to energy production, cognitive function and endurance both in general and specifically concerning muscles.

For the past five years as part of their economic development strategies, 28 U.S. metro areas have been developing global trade and investment plans. These metro areas have devoted substantial energy and resources to this process, motivated by the conviction that global engagement will have a significant impact on their economies. But things often change once plans are released: The conviction that fuels the planning process doesn’t necessarily translate into the resources required to put these plans into action.

A decline in workers’ power, rather than an increase in corporations’ monopoly power, likely explains the co-existence of four significant trends in the U.S. economy since the early 1980s: a declining share of national income going to labor, increased market values of corporations, low average unemployment, and low inflation, says a paper to be discussed…

Different pollution control policies, even if they achieve the same emissions goal, could have importantly different effects on the composition of the energy sector and economic outcomes. In this paper, we use the G-Cubed1 model of the global economy to compare two basic policy approaches for controlling carbon emissions from power plants: (1) a tradable…

Executive Summary Problems that arise in the implementation process make it less likely that policy objectives will be achieved in many government programs. Implementation problems may also damage the morale and external reputations of the agencies in charge of implementation. Although many implementation problems occur repeatedly across programs and can be predicted in advance, legislators…

This home for a family of three and two cats has been built with efficiency, comfort and health in mind.

Architect Jonathan Kearns shows that you can have it all.

It's urban, Passive House and prefab. What's not to love?

Let's hope that unlike the Oscars, they make the right choices and open the right envelopes.

The Forever Floatride GROW is made with castor beans, algae, eucalyptus, and natural rubber.

Human Resources

Turtle Beach Reveals the All-New Elite Pro

Turtle Beach Reveals the All-New Elite Pro

#262 — April 15, 2020 Read on the Web StatusCode Weekly Covering the week's news in software development, ops, platforms, and tooling. GitHub Shakes Up Pricing, Makes Most Core Features Free — One of the good consequences of Microsoft acquiring GitHub seems to be that they want to open it up to everyone without any barriers, so now you can use GitHub for private development with unlimited collaborators for free, and even the enterprise features are cheaper now. Nat Friedman (GitHub) Comparing HTTP/3 vs. HTTP/2 Performance — HTTP/3 is still in a draft status spec-wise, but it’s already being supported here and there, including on Cloudflare. This post covers where HTTP/3 is right now, why it matters, and some basic benchmarks. Sreeni Tellakula (Cloudflare) We Now Offer Remote Go, Docker or Kubernetes Training — We offer live-streaming remote training as well as video training for engineers and companies that want to learn Go, Docker and/or Kubernetes. Having trained over 5,000 engineers, we have carefully crafted these classes for students to get as much value as possible. Ardan Labs sponsor Ask HN: How to Rediscover the Joy of Programming? — A popular Hacker News discussion from this week about how to make programming really click for you, rather than being merely a daily slog. Hacker News How Deploys Work at Slack — When you’re running a service that’s used at the heart of so many companies, like Slack, deploys require a careful balance of speed and reliability. This is a very high level look at what Slack does. Slack Engineering Quick bytes: The English mathematician John Conway, perhaps best known for his Game of Life cellular automaton, has died. Windows is adding support for seeing files from Linux filesystems in File Explorer. Remember how New Jersey is looking for COBOL developers? Well, IBM are launching a COBOL training course too. AMD is claiming their new EPYC Rome 7Fx2 processors have the world's fastest per-core performance. Well, for x86 server CPUs anyway. Scaleway were famous for offering cheap ARM VMs and servers, but are now dropping ARM entirely. Amazon Elastic Container Service and AWS Fargate now support Amazon Elastic File System. ???? Jobs Full-Stack Developer (Skien, Norway) — We are looking for a full-stack dev with a solid track record to help us adapt to tomorrow's security requirements. OKAY Find a Job Through Vettery — Vettery specializes in tech roles and is completely free for job seekers. Create a profile to get started. Vettery ???? Stories and Opinions The Death of Hype: What's Next for Scala — Most languages go through a ‘hype cycle’ and Scala’s initial peak was quite a few years ago now but what’s the long term outlook like? Haoyi The Case for Human-Centric Observability Lightstep sponsor Clocking a 6502 to 15GHz — Via emulation, of course :-) Chris Evans The Malleable Systems Manifesto — An attempt to explore the idea of software being easy to change, reusable, sharable, and thoughtfully crafted. Malleable Systems Collective What Outranks Thread Priority? — When reawakening his laptop because to take longer and longer, Bruce set out to find the cause.. Bruce Dawson Why NextDNS Is My New Favourite DNS Service — Note: This is about using a third party DNS service as a client rather than for serving records. Stanislas Lange ???? Tutorials How to Monitor Your Web Page's Total Memory Usage with performance.measureMemory() — Learn how to measure memory usage of your web page in production to detect regressions. (Chrome only, for now.) Ulan Degenbaev How Anti-Cheat Systems Detect System Emulation — Not an area I’m involved in but this is fascinating. These folks really know their stuff. Daax, iPower, ajkhoury, and Drew ▶  Easy And Correct High Availability Postgres with Kubernetes — A 50 minute talk from PostgresOpen 2019 that goes all the way ‘from containers up’ until actually doing stuff with Postgres. Steven Pousty Some GitHub Pro-Tips Direct from GitHub — Lee Reilly is a developer and marketer at GitHub and has a whole bunch of genuinely useful GitHub power user tips here. Lee Reilly (GitHub) Untangling Microservices, or Balancing Complexity in Distributed Systems — “The microservices honeymoon period is over.” Vladik looks at why, as well as at common design issues that turn microservices into ‘distributed big balls of mud’. Vladik Khononov ▶  Explore Your Microservices Architecture with Graph Theory and Network Science — Can we improve microservice architectures using graph theory? Apparently yes. Nicki Watt Continuous Deployments for WordPress Using GitHub Actions — Shipping code to a production server often requires paid services. With GitHub Actions, Continuous Deployment is free for everyone. Read how to set that up. Steffen Bewersdorff The DevSecOps Security Checklist — The checklist brings security, operations & engineering together to up-level security without impacting velocity. Sqreen sponsor A Beginners Guide to Basic Indexing in Postgres James Bannister ???? Code and Tools The Desmos Graphing Calculator — One of those long-standing tools I lean on every now and then that I think everyone should know about. Ideal for graphing functions, doing approximations, etc.. and you don’t have to sign in or anything ???? Desmos All 200+ Google Cloud Products Described in 4 Words or Less — This is a neat poster. We need AWS and Azure versions of this as well. Greg Wilson IntelliJ IDEA 2020.1 Released — Now supports Java 14 and its new features. JetBrains Portray: A Python3 Documentation Generation Tool — I’m only a Pythonista on rare occasion, but this looks really neat. Timothy Crosley mv.sh: Rename Files with mv Without Typing The Name Twice Přemek Vyhnal regex2fat: Turn Your Favorite Regex into FAT32 — This is an absolutely terrible idea (but in a fun, entertaining way ????) 8051Enthusiast The Simpsons in CSS — Just a bit of fun, but neat to see what you can whip up with (a lot of) CSS. Chris Pattle

Indian shuttlers Ashwini Ponnappa and N Sikki Reddy have finally got some time to pause and reflect due to the COVID-19 pandemic and they are making the most of it by creating a database to analyse their past performances while waiting for another shot at Olympic qualification. The coronavirus outbreak has left over 1.2 lakh people dead and infected nearly 2 million globally, and brought all sports activities, including badminton, to a halt after countries imposed lockdowns. Ashwini and Sikki are doubles specialists and endured an underwhelming season last year. The time at hand has given them a chace to analyse the past performances.

"We don't have any one to sit and do analysis for us, so now that we have time, I'm doing some analysis of our performance. I am jotting down points, about areas where I can improve. I started with my matches and then other players on tour," Ashwini, who represented India at the London and Rio Olympic Games, told PTI. "You can always watch and analyse and understand the patterns but it is different when you see things on paper. It is more concrete. So trying to set up a complete database. My brother will help me out. He made an app for me in the past." Ashwini and Sikki fell at the first hurdle 13 times in 20 tournaments last year, and exited from the second round thrice.

Ashwini also picked up a calf injury during the Syed Modi International but the duo was still confident of qualifying by performing well in the remaining Olympic qualifiers. But with Badminton World Federation (BWF) cancelling all tournaments due to the coronavirus pandemic, their fate remains uncertain. "The problem is we don't know the new BWF rules regarding the qualification. There is one year left now, you can't take a two year old performance to select for Olympics, it has to be present performance, so we have to wait," said Sikki. "In badminton, there is a ranking cut off, so how will they accommodate the cancelled qualifiers, how will they count the ranking points, everything is too messed up now," she added. Sikki and Ashwini had reached the finals at Hyderabad Open Super 100 and Maldives International Challenge, last year.

The Indian pair is ranked 28th and will need to be inside top 16 on April 29, 2021 -- the new Olympic cut off date. Ashwini said: "Me and Sikki were confident of doing well in the 4-5 tournaments left but now no one knows what would be the criteria of Olympic qualification and BWF can't really say anything with things changing every moment." They are using the coronavirus-forced break to learn cooking, besides doing some wall practice and exercises for physical fitness. Talking about the effects of the lockdown on mental health, Sikki said: "We have been travelling a lot all these years and now for a month, we are at home, it is fine. But what if it is for 2-3 months, then it will get tough to stay away from the game.

"So it is important to stay motivated for once the lockdown is lifted because you will in a comfortable zone in the break and then all of a sudden you will need to push yourself." Ashwini added: "...now that Olympics have been postponed, nothing is certain and it is tough, you have to be really strong." The economic fallout of the coronavirus outbreak has hit sports hard and Ashwini said badminton too will be affected. "It will hit in terms of sponsors, in terms of tournaments being conducted because countries need sponsors to host events, and after this, I'm not sure what the economic status of many countries would be. "The way things are, it is will be tough to host tournaments, it will not be easy for countries to have tournaments with many big companies shut and struggling to survive," she signed off.

Catch up on all the latest sports news and updates here. Also download the new mid-day Android and iOS apps to get latest updates.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

The art display at the debut edition of the festival

This weekend, if you step into the heritage precinct of the Great Eastern Mills compound in Byculla, you’ll get to feast your eyes on oil and watercolour paintings by 50 artists from across India. The showcase is part of the second edition of Art 35, a three-day carnival that celebrates affordable art. “Though we had a basic festival last year, I have taken it to a bigger scale this year by curating carpet displays, fashion apparel, jewellery and food stalls; paper and origami workshops for children and music performances too,” shares Charu Tewari, CEO of Ficus Fine Living, that’s presenting the festival.

Mooralala Marwada

The performance line-up includes an afternoon of Sufi renditions by Mooralala Marwada, a well-known folk singer from the Janana village in Kutch district of Gujarat. The artiste, who sings in the Kaafi form of music, will regale the audience with poetry of Kabir, Mirabai and Ravidas. Other must-catch acts include a Dastangoi storytelling session with Ankit Chadha and a stand-up comedy show titled Oye... Stand Up by Ankita Shrivastav and Mohit Sharma. The latter will also perform a solo act of Toba Tek Singh. The play based on Saadat Hasan Manto’s famous short story set in the aftermath of Partition will see the actor don 19 characters in 60 minutes.

Mohit Sharma in an earlier performance of Toba Tek Singh

The fest also offers a range of workshops — from one on digital photography by Himanshuu Chandrakant Sheth to tarot card reading by Ruchi Shah, finger painting, fabric painting, mural painting, collage making as well as cupcake decoration with fondants and frostings. Each workshop is curated for specific age groups, including two-year-olds.

What’s a carnival without yum food? Dig into chaat, sandwiches, baos and organic fare from the stalls set up at the fest. These include gourmet lunchboxes for `500 whipped up by Savor, a subscription service launched by the folks behind The Secret Supper Project along with probiotic European fermented milk drink, Kefir, by Moina Oberoi, who runs the city’s first Kefir delivery service. You can also binge on Mutton Kheema Samosas, biryani and other sumptuous fare from a pop-up by The Bohri Kitchen.

If you’re looking for retail therapy, check out faux and semi precious jewellery, fashion apparel by Neelu Oberoi as well as exotic carpets and hides from The Merge Projekt in Bandra.

Irrfan Khan found success even in the harshest of times. The greatest stories are born out of sheer and scarring rejections and that's what Khan had to go through during his early years in the Hindi film industry. I'm reminded of an interview when he spoke about crying profusely on Raghubir Yadav's shoulders after Nana Patekar was given the role he was playing in Mira Nair's Salaam Bombay. But he knew he wanted a life and career in front of the camera.

Another great thing about success is that it never discriminates. Khan's was an unconventional aura yet very charming. He hailed from Jaipur, stayed at Tonk Road and had dreams of making it in Bollywood. The nation saw him for the first time in the immensely successful serial, Chanakya, and his eyes were so gripping and powerful, the viewers couldn't help but be hooked by his persona. He was here to stay.

His early years in Hindi films may have been unsensational but never once anyone doubted his tenacity as an artist. Even in smaller roles like Kasoor and Footpath, you could see the sincerity and earnestness with which he approached these characters. There was something special about his emotions and gravitas that with the same amount of expressions, he could be both chilling and comical. On one hand, we had a film like Gunaah, where he played an inebriated and innocuous police officer, and on the other hand was a film like Hindi Medium, where he made the audiences laugh and even cry.

He won the National Award for Paan Singh Tomar, a film that was driven by rust and robustness, and so was his performance as the eponymous character. It was only after this that he began to get roles that were not only exciting but also very exhilarating, for him and us, both. In The Lunchbox, he played Saajan, an ageing and ordinary man who falls in love with a woman he has never met, thanks to her delicious food that accidentally lands at his office desk. It was a restrained, real, and rousing performance that will always stay as delicious and fresh as the food he consumed.

Another crackling performance was in Shoojit Sircar's Piku, where he was pretty much stuck between a clumsy father and his cantankerous daughter. His deadpan demeanour always works in favour of the films he's a part of, and Piku was one of them. Call it the magic of the narrative or his own Midas touch that even if a single muscle doesn't move on his face, we know exactly how and what he's feeling. And that's precisely what he aspired for, to be a great artist. He never craved fame.

He once said, "Wanting fame is a disease and one day, I want to be free from this disease." Today, by God's will, he has been set free from all his pain and suffering as he departs, leaving behind tons of memories and superlative films and performances. Rest in peace, Irrfan Khan, until we meet again!

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

Actor Kartik Aaryan said playing two characters in one movie would seem scary, but if the transition from Veer to Raghu in "Love Aaj Kal" was smooth he credits the film's director Imtiaz Ali for it. The actor feels Ali brings out great performances from actors in his movies.

Kartik took to Instagram and shared a still from "Love Aaj Kal", and also a picture of himself along with Ali. Alongside the image he wrote: "When you first dream of being in films, you act in front of the mirror and nail it every time, and the world of movies seems magical.?Then you get a movie. You see the camera and are unnerved. It's bigger than the suitcase you brought to Mumbai. The bright lights seem to be scolding you for not landing on a one inch tape mark and wasting everyones time."

"The first few years become about trying not to look nervous.?Then you get an Imtiaz Ali movie. The moment he narrates the story, you are pulled into a dream. I don't even remember seeing the camera on his set, he‘d always be standing wherever I looked after cut. He was never at the monitor, he was by my side. The lights on Imtiaz Ali's set help you find those tape marks," he added.

Kartik claimed he never experienced the kind of love and appreciation he got for his performance in "Love Aaj Kal". "And that too from some of my favourite filmmakers and people I most respect in the industry. How ironic that the making of this film felt most effortless. It would scare me to think of doing two characters in one movie. And here, I didn't even realise how smoothly I was being transitioned between #Veer and #Raghu," he wrote.

"For an actor, there is no better environment than being In front of that mirror. Imtiaz Ali takes you there. This is the reason why so many great actors' greatest performances have been in Imtiaz Ali films," Kartik added.

The actor then praised Ali and called him a "magician". "Imtiaz Ali director nahi hain, jadugar hain (Imtiaz Ali is not a director but a magician)! Thank you sir for giving me the best performance of my career yet. @imtiazaliofficial #LoveAajKal."

"Love Aaj Kal" co-starring Sara Ali Khan released on Valentine's Day this year. It traced love stories of two different eras -- the first is set in the late 1980s-early nineties, and unfolds between Raghu and Leena. The other love story, set in the present time, happens between Veer and Zoe.

The film is a retelling of Ali's own film of 2009 that starred Deepika Padukone and Saif Ali Khan, and was a hit. "Love Aaj Kal" 2020 fared below expectation at the box-office and was also critically panned.

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

Lady Gaga on Sunday kicked off the virtual concert One World: Together At Home online with her soulful Smile performance. According to Variety magazine, Smile is a classic majorly popularised by Jimmy Durante and Nat King Cole.

The musician had co-ordinated with the leaders from the World Health Organisation (WHO) and other musicians to begin the show.

Lady Gaga started the show by asking viewers to put their wallets aside as the show wasn't a fundraiser and didn't ask for donations. The online concert was organised to express gratitude towards the frontline workers in the fight against COVID-19.

Terming the special show as the 'love letter to the world,' the pop star shared pictures and videos of other performers as well.

Over 70 artists and celebrities from across the globe had joined the WHO's initiative of the online concert to thank and celebrate the healthcare workers fighting the pandemic.

According to The Hollywood Reporter, the virtual concert raised over USD 127 million for the relief efforts of COVID-19.

Some of the artists that were a part of the show are Elton John, Lizzo, Jennifer Lopez, Taylor Swift, Madonna, Priyanka Chopra, Shah Rukh Khan, Celine Dion, and the Rolling Stone.

The show was hosted by the most popular hosts Jimmy Kimmel, Jimmy Fallon, and Stephen Colbert.

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever

Taylor Swift won millions of hearts with her performance of hope at the virtual concert One World: Together At Home where she performed Soon You'll Be Better.

According to E! Online, the Grammy winner musician didn't use words but the lyrics of her song and her music to do the talking while she expressed gratitude towards the frontline workers during the show.

The singer was seen spreading a ray of hope as she sang, "Soon you'll be better, cause you have to."

Over 70 artists and celebrities from across the globe had joined the WHO's initiative of the online concert to thank and celebrate the healthcare workers fighting the pandemic.

Some of the artists that were a part of the show are Elton John, Lizzo, Jennifer Lopez, Lady Gaga, Madonna, Priyanka Chopra, Shah Rukh Khan, Celine Dion, and the Rolling Stone.

According to The Hollywood Reporter, the virtual concert raised over USD 127 million for the relief efforts of COVID-19.

The show was hosted by the most popular hosts Jimmy Kimmel, Jimmy Fallon, and Stephen Colbert.

Catch up on all the latest entertainment news and gossip here. Also, download the new mid-day Android and iOS apps.

Mid-Day is now on Telegram. Click here to join our channel (@middayinfomedialtd) and stay updated with the latest news

This story has been sourced from a third party syndicated feed, agencies. Mid-day accepts no responsibility or liability for its dependability, trustworthiness, reliability and data of the text. Mid-day management/mid-day.com reserves the sole right to alter, delete or remove (without notice) the content in its absolute discretion for any reason whatsoever