ring How Offices Are Preparing for Workers' Return By feedproxy.google.com Published On :: Thu, 07 May 2020 00:00:00 -0500 From smartphone-operated elevators to contactless coffee machines, businesses are trying to eliminate major touchpoints to help deter coronavirus spread in the workplace. Full Article
ring A New Era of Virtual Hearings for Pro Standards Enforcement By feedproxy.google.com Published On :: Thu, 07 May 2020 00:00:00 -0500 Rather than waiting for offices to reopen, REALTOR® associations are conducting timely, safe, and efficient ethics hearings through Zoom. From the virtual 2020 REALTORS® Legislative Meetings, April 27-May 15 Full Article
ring AT#304 - Travel to The RIng of Kerry in Ireland By europe.amateurtraveler.com Published On :: Sat, 26 Nov 2011 14:00:00 +0000 The Amateur Traveler talks to Jessie Voigts from Wandering Educators about County Kerry and the Ring of Kerry in Ireland. County Kerry is a popular tourist region in Ireland. Full Article
ring ‘Man of God’ NFL Star Points Out Things To Be Grateful for During the Pandemic: ‘There’s So Much’ By www.westernjournal.com Published On :: Fri, 08 May 2020 21:58:25 +0000 During times of panic and suffering, it is important to take a step back and remember that “God is always in control.” One NFL star known for proudly displaying his faith made that message quite clear during an episode of the Fox Nation show “Bible Study: Messages of Hope” which debuted this week. Demario Davis,… The post ‘Man of God’ NFL Star Points Out Things To Be Grateful for During the Pandemic: ‘There’s So Much’ appeared first on The Western Journal. Full Article Lifestyle News Sports Christianity Coronavirus Faith God Health New Orleans Saints NFL US News
ring Florida Fishermen Nab 6-Foot Bull Shark During First Weekend of Reopened Beaches By www.westernjournal.com Published On :: Sat, 09 May 2020 14:52:59 +0000 Everybody wanted to get to the shore last weekend when the state of Florida reopened its beaches. But one of the beachgoers who came in for some extra attention was a six-foot-long bull shark caught near Navarre Beach, according to WKRG-TV. Video shot by Shelley Goudy of Fort Walton showed several men gathered around the… The post Florida Fishermen Nab 6-Foot Bull Shark During First Weekend of Reopened Beaches appeared first on The Western Journal. Full Article News Animals Coronavirus Florida nature US News Wildlife
ring Hurricane Harvey: Delivering Managed IT Services During a Catastrophe By feedproxy.google.com Published On :: Tue, 29 Aug 2017 15:00:00 +0000 Full Article Manage North America Uptime
ring 17 Indicted in Bust of $32 Million Online Gambling Ring By feedproxy.google.com Published On :: Wed, 28 Oct 2015 18:40:11 EST The online gambling ring allegedly used an offshore website to help book $32 million in illegal sports wagers placed by more than 2,000 bettors in the United States. Full Article
ring 10 of the best fitness trackers for monitoring heart rate By feedproxy.google.com Published On :: Sat, 27 Oct 2018 09:00:00 +0000 BEST FITNESS TRACKER DEALS: Fitbit - Charge 3 Activity Tracker + Heart Rate — $99.95 (save $30) Garmin - Forerunner 645 Music GPS Heart Rate Monitor Running Watch — $449.99 3Plus - HR Activity Tracker + Heart Rate — $49.99 Wellness is a buzzy word lately. Over the past few years, we’ve seen a surge in all things health, wellness, and spirituality. Juice bars are popping up, boutique studios are becoming more accessible, and essential oils are chilling us out. Self-care is becoming more of the norm too, but amidst all this hype, it can be challenging to find the right routine that promotes good exercise, sleep, vitals, and mindset. Read more...More about Apple Watch, Fitness Trackers, Smart Watch, Heart Rate Monitor, and Mashable Shopping IMAGE: Amazon BEST OVERALL Apple Watch Series 4 Take heart monitoring to the next level with the Apple Watch Series 4's amazing EKG feature and FDA-cleared precision. Warranty: 90 days with Apple Care+ Smartphone compatibility: Yes Battery life: 22 hours Weight: 1.06 oz What you'll get: A case, band, 1m magnetic charging cable, and 5W USB Power Adapter $236.98 from Amazon IMAGE: Amazon BEST BANG FOR YOUR BUCK Polar A370 Fitness Tracker Smartphone compatibility and a variety of wellness features makes Polar’s A370 Fitness Tracker our top choice for health management. Warranty: 2 years Smartphone Compatibility: Yes Battery life: 4 days Weight: 13.8 ounces What you’ll get: A Polar A370 Fitness Tracker, a band, a charging cable, and a manual $114.99 from Amazon IMAGE: Amazon EASIEST TO USE Fitbit Charge 3 Fitness Activity Tracker The new Charge 3 provides no-fuss wellness features to take your daily sleep, workouts, and vitals to the next level. Warranty: 45-day guarantee and 1 year warranty Smartphone compatibility: Yes Battery life: 7 days Weight: 4.8 ounces What you’ll get: A Fitbit Charge 3, classic wristbands (both small & large), and a charging cable $119.03 from Amazon IMAGE: Best Buy BEST FOR ATHLETES Garmin Forerunner 735XT Smartwatch With sport-specific settings, advanced training feedback, and a connected app, Garmin’s Forerunner 735XT Smartwatch is the perfect fitness companion for athletes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 1 day Weight: 1.4 ounces What you’ll get: A Garmin Forerunner 735XT Smartwatch, a charging/data clip, and a manual $349.99 from Best Buy IMAGE: Amazon BEST FOR TECH ENTHUSIASTS Nokia Steel HR Hybrid Smartwatch Add some tech to your exercise regimen with the Nokia’s Steel HR Hybrid with Alexa integration and three different heart monitor modes. Warranty: 1 year Smartphone compatibility: Yes Battery life: 25 days Weight: 8.2 ounces What you’ll get: A Nokia Steel HR Hybrid Smartwatch and a CR2 battery $199.95 from Amazon IMAGE: Amazon BEST FOR WATER SPORTS Garmin vívoactive 3 Warranty: 1 year Smartphone compatibility: Yes Battery life: 10 days Weight: 1.44 ounces What you'll get: A vívoactive 3 Fitness Tracker, a charging/data cable, and manuals $319.99 from Amazon IMAGE: Amazon BEST FOR STYLE Motiv Ring Warranty: 45-day guarantee and 1-year warranty Smartphone compatibility: Yes Battery life: 3 days Weight: 1.6 ounces What you'll get: A Motiv Ring, sizing set, and two slim charging docks $199.99 from Amazon IMAGE: Amazon BUDGET PICK Microtella Fitness Tracker Microtella’s Fitness Tracker is affordable, monitors your heart rate, and comes with 14 different fitness settings for personalized workout stats. Warranty: None Smartphone Compatibility: Yes Battery life: 7 days Weight: 4 ounces What you’ll get: A Microtella Fitness Tracker, a band, and a USB charger $39.99 from Amazon IMAGE: Amazon BEST OF BOTH WORLDS Samsung Galaxy Fit The perfect midpoint between the Fitbit and Apple Watch, the Samsung Galaxy Fit is great for tracking your high-intensity activities and for managing your daily life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 7 days Weight: 3.2 ounces What you'll get: Samsung Galaxy Fit, charging cable, manuals $79 from Amazon IMAGE: Amazon BEST ON-SCREEN WORKOUTS Fitbit Versa The Fitbit Versa is best for those who need some extra guidance in the gym, and thanks to its comprehensive array of on-screen workouts, you'll get exactly that. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 4 days Weight: 5.12 ounces What you'll get: Fitbit Versa, charging cable, manuals $199.95 from Amazon IMAGE: Amazon BEST BATTERY LIFE Wahoo TICKR Won't take up precious real estate on your wrists and will provide personalized heart rate training, as well as an unbeatable 12-month battery life. Warranty: 1 year Smartphone Compatibility: Yes Battery Life: 1 year Weight: 2.4 ounces What you'll get: Wahoo TICKR, battery, manuals $45.94 from Amazon Full Article Apple Watch Fitness Trackers Smart Watch Heart Rate Monitor Mashable Shopping
ring Remembering Freeman Dyson By feedproxy.google.com Published On :: Wed, 04 Mar 2020 14:31:30 +0000 Freeman Dyson died last week at the age of 96 after injuring himself in a fall in the cafeteria at the Institute of Advanced Studies in Princeton, where he had continued to work right up to the end. I can’t resist adding to the outpouring of appreciation and love that has ensued. He has an […] Full Article Innovation & Disruption Commentary
ring The surreal experience of flying during a pandemic By feedproxy.google.com Published On :: Fri, 08 May 2020 09:54:21 PDT "[F]lying during a pandemic turned out to be more stressful—and surreal—than I’d planned for," writes McKay Copkins in The Atlantic. After two months of social distancing Copkins went on a reporting trip that required a plane flight. He was looking forward to the trip, but as soon as he got on the plane he realized that air travel is no fun during a pandemic. I arrived at my assigned row, and found a stocky, gray-haired man in the seat next to mine. When I moved to sit down, he stopped me. “Sit there,” he said gruffly, pointing to the aisle behind us. “Social distance.” Not eager for a confrontation, I decided to comply. Within seconds, though, a flight attendant materialized and ordered me back to my assigned seat. My recalcitrant would-be seatmate, vigorously objecting to this development, responded by blocking my entrance to the row with his leg. Photo by Ethan McArthur on Unsplash Read the rest Full Article Post air travel coronavirus COVID-19
ring Stuck on cruise ships during pandemic, crews beg to go home By www.ctvnews.ca Published On :: Sat, 9 May 2020 06:18:00 -0600 Tens of thousands of other crew members have been trapped for weeks aboard dozens of cruise ships around the world -- long after governments and cruise lines negotiated their passengers' disembarkation. Some have gotten ill and died; others have survived but are no longer getting paid. Full Article
ring Sport24.co.za | Hard work paid off for former Springbok Bands By www.sport24.co.za Published On :: Sat, 09 May 2020 16:32:59 +0200 It isn’t surprising that former Springbok tighthead Richard Bands is remembered mainly for one bullocking run for the Springboks in Dunedin in 2003. Full Article
ring Where is Unemployment Slowing Faster During the Pandemic? By feedproxy.google.com Published On :: Fri, 01 May 2020 16:00:58 +0000 Where is Unemployment Slowing Faster During the... This post takes a deeper look at unemployment insurance claims and provides some additional insights into the labor market for each state. By: Nadia Evangelou Full Article
ring Sheltering in Place in Mexico City By feedproxy.google.com Published On :: Sun, 29 Mar 2020 17:01:28 +0000 This is not where I thought I’d be. If things had gone to plan, I would now be on a bus moving through the Peruvian countryside, smiling at the memory of my meals at Central and Maido, looking forward to sandboarding in Huacachina, seeing Machu Picchu, and exploring the Galapagos a few weeks after that. … Sheltering in Place in Mexico City Read More » The post Sheltering in Place in Mexico City appeared first on Adventurous Kate. Full Article Blog Mexico
ring BioLite HeadLamp 200 Is the Featherweight Head Lamp You’ll (Probably) Forget You’re Wearing By feedproxy.google.com Published On :: Fri, 06 Mar 2020 21:43:29 +0000 It's not the brightest headlamp on the market, but it's more than adequate for cooking, reading, or finding a pee tree in the dark. Plus, it's comfortable, easy-to-use, and USB rechargeable. The post BioLite HeadLamp 200 Is the Featherweight Head Lamp You’ll (Probably) Forget You’re Wearing appeared first on Vagabondish. Full Article Modern Vagabond Review Camping
ring Hiring programmers with a take-home test By feedproxy.google.com Published On :: Tue, 28 Apr 2020 22:31:34 +0000 There’s no perfect process for hiring great programmers, but there are plenty of terrible ways to screw it up. We’ve rejected the industry stables of grilling candidates in front of a whiteboard or needling them with brain teasers since the start at Basecamp. But you’re not getting around showing real code when applying for a… keep reading Full Article Uncategorized
ring Video: John Roderick on String Art Owls, Copper Pipe, and Bono's Boss By feedproxy.google.com Published On :: Fri, 21 Jan 2011 18:51:26 +0000 [jump to video] Long story (not very) short? One night in 2003--after killing it in front of audience of about 30 lucky people in Oakland--The Long Winters needed a place to crash, and my wife and I were happy to oblige. So, they drove their Big Stinky Blue Van over the bridge, slept on our floor, and by breakfast the next morning, it'd become clear to me that I'd provided lodging to a man who was not only very likely a member of my karass--he was also one of the smartest bullshit artists I'd ever met. Almost eight years later, although I don't see him nearly as much as I'd like, I still count the guy as one of my best pals ever. That's John Roderick. And, I think you need to know about him. John doesn't read this site--he's more of a Twitter person--so I don't risk feeding his astounding excess of dignity by saying he's one of the most gifted writers and bon vivants of our generation. He's just the best. In large part because he's congenitally incapable of suffering bullshit. This was never more apparent than the Saturday morning in 2007 when we sat in my back yard and talked about a lot of stuff. Playing guitar, advertising on the web, the evil work of promoters, and why everyone is always trying to shortchange everyone on copper pipe. That talking became a four-part interview I ran on the late and occasionally lamented The Merlin Show, and, to this day, it's one of my favorite things I've been lucky enough to post to the web. So, y'know how I'm definitely "not for everyone?" Well, John is really "not for everyone." He's opinionated and arrogant and undiplomatic and unironically loves Judas Priest--meaning everyone will find at least one thing not to like about him. Despite being hairy and enjoying laying on your bed, John is not exactly a teddy bear. But, John's also right a lot. And, he never sands off the edges of his personality or opinions to make you theoretically "like" him. Which, it will come as no surprise to you, is a big reason I love the guy more than a free prime rib dinner. So, why the jizzfest about that awful jerk, John Roderick? Because, as I noted the other day on the Twitter, in our first episode of Back to Work I misattributed a line that should have been credited to John. Which in itself is unimportant, except inasmuch as finding that link to correct the error got me watching our 50-some minutes of chatting again. I also received some at-responses and emails that reminded me how much people enjoyed our chat. But, really it made me realize how much that rambling morning in my back yard still resonates so much with stuff I care a lot about. Independence. Agency. Directness. And, never apologizing for wanting to get paid. Also, guitars and talkative hippies. So, anyway. John. I edited all four parts of the video into one big (streamable/downloadable) movie that should make it way easier to watch at a sitting. Should that interest you. Which it may not. Which, as ever, is totally fine, and kind of the point. But. If you like Dan and my new show (and, seriously—God bless you magnificent bastards who helped briefly make B2W the most popular podcast in the world [gulp]), I think you'll really like this interview a lot too. I hope so, anyway. Thus, submitted for your disapproval, permit me to present my four-year-old visit with the acerbic, opinionated, and reportedly unlikeable bullshit artist whom I respect and adore more than just about anybody. Meet Hotrod. Vimeo Page Direct Download Link (589 mb, requires login) ”Video: John Roderick on String Art Owls, Copper Pipe, and Bono's Boss” was written by Merlin Mann for 43Folders.com and was originally posted on January 21, 2011. Except as noted, it's ©2010 Merlin Mann and licensed for reuse under CC BY-NC-ND 3.0. "Why a footer?" Full Article Brady's Bits John Roderick The Merlin Show video
ring Mother Nature blankets parts of Muskoka with spring snowfall By barrie.ctvnews.ca Published On :: Fri, 8 May 2020 15:03:52 -0400 The calendar may say May, but that didn't stop Mother Nature from blasting some wintry weather in Muskoka on Friday. Full Article
ring Legal landscape murky for B.C. workers and employers during pandemic By bc.ctvnews.ca Published On :: Fri, 8 May 2020 19:39:00 -0700 Labour laws haven’t changed in our province, but legal experts are already urging B.C. employers to be flexible and reasonable — while warning employees they may not be legally protected if they refuse work during the pandemic. Full Article
ring Police investigating child luring attempt on Vancouver's West Side By bc.ctvnews.ca Published On :: Fri, 8 May 2020 20:58:10 -0700 The incident happened in the West Point Grey neighbourhood around 3:30 p.m. on Wednesday, police said. Full Article
ring BREAKING: 43-Yr-Old Father Of 9, Dollar Store Sec Guard, Shot DEAD While Allegedly Trying To Enforce MI Gov Whitmer’s Face Covering Exec Order By 100percentfedup.com Published On :: Wed, 06 May 2020 18:27:38 +0000 The following article, BREAKING: 43-Yr-Old Father Of 9, Dollar Store Sec Guard, Shot DEAD While Allegedly Trying To Enforce MI Gov Whitmer’s Face Covering Exec Order, was first published on 100PercentFedUp.com. Will the mainstream media report about the senseless death of a 43-year-old father of nine, who would have been alive today if it were not for VP wannabe, Gretchen Whitmer's executive order that forced him to respond to a customer not wearing a face mask? Continue reading: BREAKING: 43-Yr-Old Father Of 9, Dollar Store Sec Guard, Shot DEAD While Allegedly Trying To Enforce MI Gov Whitmer’s Face Covering Exec Order ... Full Article Featured Left News Politics
ring Chicago Inmate Switches Identities While Wearing Mask…Is Released from Jail By 100percentfedup.com Published On :: Thu, 07 May 2020 03:16:17 +0000 The following article, Chicago Inmate Switches Identities While Wearing Mask…Is Released from Jail, was first published on 100PercentFedUp.com. A Cook County, Chicago inmate, was able to switch identities with another inmate allowing the wrong inmate to be released. How did they carry that off without anyone catching them? The inmate was wearing a mask when he was released, so it wasn’t as easy to identify him. Last Saturday, Quintin Henderson (pictured below), 28, […] Continue reading: Chicago Inmate Switches Identities While Wearing Mask…Is Released from Jail ... Full Article Breaking Crime Featured
ring Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom By 100percentfedup.com Published On :: Fri, 08 May 2020 18:49:10 +0000 The following article, Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom, was first published on 100PercentFedUp.com. The normalizing of pedophilia is not a far-right conspiracy theory... Continue reading: Fed Judge Releases 21-Yr-Old Man To “Clean and Sober House” After Appearing In Court For Sexually Assaulting 12-Yr-Old Girl For One Month While Hiding In Her Bedroom ... Full Article Featured Left News
ring Busted! Late-Night Hack Comedian, Jimmy Kimmel Is Forced To Apologize For Sharing Highly Edited Video Of VP Pence To Make Him Look Bad By 100percentfedup.com Published On :: Sat, 09 May 2020 01:45:58 +0000 The following article, Busted! Late-Night Hack Comedian, Jimmy Kimmel Is Forced To Apologize For Sharing Highly Edited Video Of VP Pence To Make Him Look Bad, was first published on 100PercentFedUp.com. Last night, Jimmy Kimmel, host of the low-rated, late-night Jimmy Kimmel Show, shared a deceptively edited video clip of Vice President Pence delivering PPE to a nursing home. Today, liberal activist Matt McDermott tweeted the videotaped segment on VP Pence that was edited to make the vice president look like he was faking a delivery […] Continue reading: Busted! Late-Night Hack Comedian, Jimmy Kimmel Is Forced To Apologize For Sharing Highly Edited Video Of VP Pence To Make Him Look Bad ... Full Article Featured Politics
ring Watch: Biden Pulls Awkward Stunt During Town Hall By 100percentfedup.com Published On :: Sat, 09 May 2020 16:08:56 +0000 The following article, Watch: Biden Pulls Awkward Stunt During Town Hall, was first published on 100PercentFedUp.com. Joe Biden began his virtual town hall on Saturday with the political stunt of wearing a mask in his own home. Biden was attempting to host a live town hall with NowThis News, but glitch after glitch happened throughout the Biden campaign’s attempt to reach supporters. When the video below begins, it looks like he’s […] Continue reading: Watch: Biden Pulls Awkward Stunt During Town Hall ... Full Article Breaking Featured Politics
ring How Winnipeggers can celebrate Mother's Day during COVID-19 By winnipeg.ctvnews.ca Published On :: Fri, 8 May 2020 17:47:00 -0600 Mother's Day is Sunday, but with COVID-19, it's forcing many to change their plans. Full Article
ring Neil Shearing By feedproxy.google.com Published On :: Wed, 29 Apr 2020 18:45:16 +0000 Associate Fellow, Global Economy and Finance Programme Biography Neil Shearing is group chief economist at Capital Economics, the leading economic research company. He heads a team of 70 economists spread across Europe, the Americas and Asia, and is responsible for driving the firm’s research agenda as well as developing its products and relationships with clients. He is also a director of the company.Neil has 20 years’ experience as a macroeconomist, built in both the government and financial sector. He presents regularly on the global economic and financial market outlook and is a well-known voice within the investment community, having worked in both London and New York.Neil has written articles in the Financial Times and a number of other newspapers, as well as appearing regularly on TV and radio.Prior to becoming group chief economist, Neil was chief emerging markets economist at Capital Economics, managing a team that won several awards for forecast accuracy. He also managed the New York office.Neil joined Capital Economics from HM Treasury where he worked as an economic adviser in various areas, including fiscal policy and global economics.He holds degrees in Economics from the University of York and the University of London and is a fellow of the Royal Society of Arts.Neil's main area of research interest is in analysing and understanding structural shifts in the global economy. This clearly touches on a wide range of issues, but a fundamental question today is whether we’re facing the end of globalisation, a key area of current work which raises several interesting questions.What does history tell us about past waves of globalisation? Are they doomed to end? What role is technology playing? Could new technologies drive another wave of integration or are they more likely to lead to re-shoring as robots replace workers? Which countries would be most vulnerable to a rollback of globalisation? Related to this, will emerging economies ever 'catch up' to income levels in developed economies? What are the implications for policy makers (governments, central banks) and global institutions (IMF, World Bank)? Areas of expertise Global economyEmerging markets (China, Latin America, Central & Eastern Europe)Monetary economicsGlobal trade and capital flows Full Article
ring Synergy in North Africa: Furthering Cooperation By feedproxy.google.com Published On :: Mon, 20 Jan 2020 15:57:54 +0000 21 January 2020 Discussions of North African integration have evoked ideas of a shared identity and a common destiny in the region. However, recent attempts to build regional blocs in North Africa have been unsuccessful. This paper examines the benefits of a ‘synergistic’ approach to North African cooperation. Read online Download PDF in English Download PDF in Arabic Dr Mohammed Masbah Associate Fellow, Middle East and North Africa Programme @MasbahMohammed LinkedIn Google Scholar Mohamed El Dahshan Associate Fellow, Middle East and North Africa Programme @eldahshan LinkedIn Google Scholar 2020-01-21-Market.jpg A Tunisian vendor poses as he sells white truffles at a market in the town of Ben Guerdane, 40km west of the Libyan border, in February 2016. Photo: Getty Images. SummaryNorth African integration is not a new idea. However, countries in the region have so far struggled to form a cohesive bloc with deep political, economic and social ties. Political instability has effectively deprioritized North African integration. A focus on thematic (political, economic and security) ‘synergies’ may provide a better framework for cooperation than seeking opportunities for all-encompassing ‘deep’ and ‘comprehensive’ integration.Governments of North Africa dedicate considerable resources to domestic security. Much of their efforts are conducted at the national-level and directed towards threats from terrorists, insurgents and militias. Improved security cooperation would achieve better outcomes and economies of scale, including efforts to tackle human trafficking.A new generation of jihadis has emerged in North Africa since 2011. Nearly 27 per cent of the 30,000 fighters who travelled to Syria are from the Maghreb. While government counterterrorism operations have been effective, countries have failed to address the root causes of radicalization.Border economies have suffered as a consequence of a security focus on terrorism and smuggling, which has rendered many previously accepted cross-border trade activities illegal. States have struggled to provide alternative livelihoods for those who have lost this source of income. Border forces tend to lack the right combination of capacity, training and equipment to secure borders and often resort to heavy-handed tactics.New thinking is required to develop a more human-centric and proactive approach to migration issues in the region, which continues to witness huge flows of migrants. The migration policy of Morocco, introduced through legislation in 2014, could be a model for North Africa.The countries of North Africa have varying economic profiles, ranging from economically diverse Morocco to oil-and-gas-dependant Libya. However, they all face similar challenges including unemployment (particularly among the young), poor public-service delivery, low FDI levels, an oversized public sector, ineffective tax collection, and high informality.Fostering entrepreneurship and the development of small and medium-sized enterprises (SMEs) are priorities for North African countries, particularly regarding job creation. Regulatory cooperation – such as harmonizing SME definitions, legislation and support institutions – across North Africa is an obvious area where further integration would encourage the development of start-ups and small businesses.With the advent of the fourth industrial revolution, North African governments must address their technological gaps and work to improve public–private cooperation. In some sectors, such as the fintech industry, North African countries can build upon nascent synergies that have developed organically, such as those of start-up incubators and angel investors that work across the region.Renewables, particularly solar energy production, are a promising development for North Africa. While regional initiatives, such as Desertec, have stalled due to political differences between countries, the sector has witnessed exponential growth in Tunisia, Egypt and Morocco, where the involvement of the private sector has proved successful. Department/project Middle East and North Africa Programme, North Africa Dialogues Full Article
ring Exploring the Transatlantic Rift By feedproxy.google.com Published On :: Thu, 27 Aug 2015 10:38:30 +0000 27 August 2015 Xenia Wickett Former Head, US and the Americas Programme; Former Dean, The Queen Elizabeth II Academy for Leadership in International Affairs @xeniawickett LinkedIn If the US and Europe drift apart, there will be grave consequences for Western global leadership. 20150827USBrandenburg.jpg An American flag flies in front of the Brandenburg Gate, near the US embassy on 7 July 2014 in Berlin. Photo by Getty Images. Is there a ‘crisis’ in the transatlantic relationship? Although the US and Europe are not irresistibly diverging, there are indications that governments and their populations on both sides of the Atlantic are becoming less aligned in their thinking and actions. And it is happening just when they need to become closer.The ‘rise of the rest’, in which new emerging markets are coming to the fore, is creating a more competitive international environment. And the West is not putting on an adequate response. Unless the US and Europe want to relinquish leadership on building global norms and standards on key issues, their leaders once again need to work more collectively together.Divides in the Atlantic communityThe structures put together in the first half of the 20th century by the Atlantic community (such as NATO, the UN, the WTO/GATT, the IMF and the World Bank) provided the architecture and norms by which everyone functioned – and thereby primed the international context in their favour.However, these institutions have become increasingly dysfunctional or unfit for purpose, and are increasingly ignored (like the UN) or replaced (as China’s new Asian Infrastructure Investment Bank [AIIB] is arguably attempting to do). That contextual advantage has gone. And there are many other good reasons to be concerned.Shared values are a notable aspect of the strong and longstanding relationship between the US and Europe. But now, although the US does appear to be coming closer to Europe on some measures (Pew polling suggests America is becoming less religious and more liberal on gay rights and recreational drugs, for instance), there is clear evidence that differences of opinion are becoming more entrenched.Policy divides between the US and Europe are commonplace, but recently the list of differences (and the degree of difference of opinion) appears to be growing. The split over joining the AIIB is the most recent of these, being a visible symptom of a larger fundamental difference of opinion on Asia. But other issues that divide include actions in Libya in 2011, Syria today, Russia, support for NATO, energy independence and what to do about climate change.The study on elite perceptions conducted by Chatham House’s US Project in 2014 made clear how important Europeans perceived America’s traditional values to be, but also raised the concern that the US was losing sight of them (citing, for example, the lack of universal healthcare and attitudes towards the death penalty and gun laws). The visceral response of the German public to the Snowden revelations is a stark example of the divide in attitudes.Special relationshipsAnecdotally, the evidence is also not good. Over the past four years the general tone of conversations in Europe about the US has changed, due to huge uncertainty about whether the US is going to continue to play the same role it has in the past or whether it will leave Europe to face its challenges alone. Meanwhile, in the US the conversation around whether Europe will step up (particularly in security) has heightened tremendously. Four years ago, no one thought to question the transatlantic relationship. Today, on both sides, there is a lack of confidence.The US-UK relationship has a special part in this – it has long been and still remains the centre-point of the transatlantic relationship. From a realpolitik perspective, the US sees the UK as valuable for three principal reasons: A) its role in the EU promoting common UK/US interests; B) the assets it brings to the table (particularly defence and intelligence); and C) its external perspective and its support internationally (ensuring the US is rarely alone). However, in the coming years A might go away and B is declining with falling defence spending, leaving only C. And a weak US-UK relationship could cause significant trouble for the wider US-Europe relationship.It is all too easy to forget the importance of the transatlantic relationship. For many it is increasingly irrelevant – the emerging powers such as China and Brazil are far more interesting. And for others it is just an ever-present reality – the Atlantic allies have been so close and through so much that nothing can change it.Neither of these is right. The transatlantic relationship is vital part of addressing global challenges and it is something that, if continued to be treated either with either contempt or ignorance, will be lost before we know it. For these reasons, the US Project is beginning new research that looks at the transatlantic relationship and asks whether there is a rift. If yes, we hope to explore what can be done to mitigate it – before it is too late.To comment on this article, please contact Chatham House Feedback Full Article
ring Biosecurity: Preparing for the Aftermath of Global Health Crises By feedproxy.google.com Published On :: Thu, 09 Jan 2020 14:16:59 +0000 9 January 2020 Professor David R Harper CBE Senior Consulting Fellow, Global Health Programme @DavidRossHarper Benjamin Wakefield Research Associate, Global Health Programme @BCWakefield LinkedIn The Ebola outbreak in the Democratic Republic of the Congo is a reminder that the security of samples taken during global health emergencies is a vital part of safeguarding biosecurity. 2020-01-09-DRC.jpg A nurse prepares a vaccine against Ebola in Goma in August 2019. Photo: Getty Images. The world’s second-largest Ebola outbreak is ongoing in the Democratic Republic of the Congo (DRC) and experts from around the world have been parachuted in to support the country’s operation to stamp out the outbreak. The signs are encouraging, but we need to remain cautious.In such emergencies, little thought is usually given to what happens to the body-fluid samples taken during the course of the outbreak after the crisis is over. What gets left behind has considerable implications for global biosecurity.Having unsecured samples poses the obvious risk of accidental exposures to people who might come into contact with them, but what of the risk of malicious use? Bioterrorists would have ready access to materials that have the characteristics essential to their purpose: the potential to cause disease that is transmissible from person to person, the capacity to result in high fatality rates and, importantly, the ability to cause panic and social disruption at the very mention of them.Comparisons can be drawn with the significant international impact of the anthrax attacks in the US in 2001. Not only was there a direct effect in the US with five deaths and a further 17 people infected, but there was a paralysis of public health systems in other countries involved in the testing of countless samples from the so-called ‘white-powder incidents’ that followed.Many laboratory tests were done purely on a precautionary basis to eliminate any possibility of a risk, no matter how remote. However, the UK was also hit when a hoaxer sent envelopes of white powder labelled as anthrax to 15 MPs.The threat of the pathogen alone resulted in widespread fear, the deployment of officers trained in response to chemical, biological, radiological and nuclear incidents and the evacuation of a hospital emergency department.We learned from the 2014–16 West Africa Ebola outbreaks that during the emergency, the future biosecurity implications of the many thousands of samples taken from people were given very little consideration. It is impossible to be sure where they all are and whether they have been secured.It is widely recognized that the systems needed at the time for tracking and monitoring resources, including those necessary for samples, were weak or absent, and this has to be addressed urgently along with other capacity-building initiatives.In Sierra Leone, for example, the remaining biosecurity risk is only being addressed after the fact. To help achieve this, the government of Canada is in the process of providing a secure biobank in the Sierra Leonean capital of Freetown. The aim is to provide the proper means of storage for these hazardous samples and to allow them to remain in-country, with Sierra Leonean ownership.However, it is already more three years since the emergency was declared over by the then director-general of the World Health Organization (WHO), Margaret Chan, and the biobank and its associated laboratory are yet to be fully operational.There are many understandable reasons for this delay, including the critical issue of how best to ensure the sustainability of any new facility. But what is clear is that these solutions take time to implement and must be planned for in advance.The difficulties of responding to an outbreak in a conflict zone have been well documented, and the frequent violence in DRC has undoubtedly caused delays in controlling the outbreak. According to figures from WHO, during 2019 approximately 390 attacks on health facilities in DRC killed 11 and injured 83 healthcare workers and patients.Not only does the conflict inhibit the response, but it could also increase the risk posed by unsecured samples. There are two main potential concerns.First is the risk of accidental release during an attack on a health facility, under which circumstances sample containers may be compromised or destroyed. Second is that the samples may be stolen for malicious use or to sell them to a third-party for malicious use. It is very important in all outbreaks to ensure the necessary measures are in place to secure samples; in conflict-affected areas, this is particularly challenging.The sooner the samples in the DRC are secured, the sooner this risk to global biosecurity is reduced. And preparations for the next emergency must be made without further delay.The following steps need to be taken:Affected countries must ‘own’ the problem, with clear national government commitment to take the required actions.Funding partners must coordinate their actions and work closely with the countries to find the best solutions.If samples are to be kept in-country, secure biobanks must be established to contain them.Sustainable infrastructure must be built for samples to be kept secure into the future.An international agreement should be reached on the best approach to take to prepare for the aftermath of global health emergencies. Full Article
ring Residually finite rationally solvable groups and virtual fibring By www.ams.org Published On :: Tue, 10 Mar 2020 10:59 EDT Dawid Kielak J. Amer. Math. Soc. 33 (2019), 451-486. Abstract, references and article information Full Article
ring Parallel Reaction Monitoring for High Resolution and High Mass Accuracy Quantitative, Targeted Proteomics By feedproxy.google.com Published On :: 2012-11-01 Amelia C. PetersonNov 1, 2012; 11:1475-1488Technological Innovation and Resources Full Article
ring A Tandem Affinity Tag for Two-step Purification under Fully Denaturing Conditions: Application in Ubiquitin Profiling and Protein Complex Identification Combined with in vivoCross-Linking By feedproxy.google.com Published On :: 2006-04-01 Christian TagwerkerApr 1, 2006; 5:737-748Research Full Article
ring Quantitative Mass Spectrometric Multiple Reaction Monitoring Assays for Major Plasma Proteins By feedproxy.google.com Published On :: 2006-04-01 Leigh AndersonApr 1, 2006; 5:573-588Research Full Article
ring Polarization of protease-activated receptor 2 (PAR-2) signaling is altered during airway epithelial remodeling and deciliation [Immunology] By feedproxy.google.com Published On :: 2020-05-08T03:41:14-07:00 Protease-activated receptor 2 (PAR-2) is activated by secreted proteases from immune cells or fungi. PAR-2 is normally expressed basolaterally in differentiated nasal ciliated cells. We hypothesized that epithelial remodeling during diseases characterized by cilial loss and squamous metaplasia may alter PAR-2 polarization. Here, using a fluorescent arrestin assay, we confirmed that the common fungal airway pathogen Aspergillus fumigatus activates heterologously-expressed PAR-2. Endogenous PAR-2 activation in submerged airway RPMI 2650 or NCI–H520 squamous cells increased intracellular calcium levels and granulocyte macrophage–colony-stimulating factor, tumor necrosis factor α, and interleukin (IL)-6 secretion. RPMI 2650 cells cultured at an air–liquid interface (ALI) responded to apically or basolaterally applied PAR-2 agonists. However, well-differentiated primary nasal epithelial ALIs responded only to basolateral PAR-2 stimulation, indicated by calcium elevation, increased cilia beat frequency, and increased fluid and cytokine secretion. We exposed primary cells to disease-related modifiers that alter epithelial morphology, including IL-13, cigarette smoke condensate, and retinoic acid deficiency, at concentrations and times that altered epithelial morphology without causing breakdown of the epithelial barrier to model early disease states. These altered primary cultures responded to both apical and basolateral PAR-2 stimulation. Imaging nasal polyps and control middle turbinate explants, we found that nasal polyps, but not turbinates, exhibit apical calcium responses to PAR-2 stimulation. However, isolated ciliated cells from both polyps and turbinates maintained basolateral PAR-2 polarization, suggesting that the calcium responses originated from nonciliated cells. Altered PAR-2 polarization in disease-remodeled epithelia may enhance apical responses and increase sensitivity to inhaled proteases. Full Article
ring Japan's ‘Indo-Pacific’ question: countering China or shaping a new regional order? By feedproxy.google.com Published On :: Wed, 08 Jan 2020 11:19:14 +0000 8 January 2020 , Volume 96, Number 1 Read online Kei Koga Japan's primary objective of the ‘free and open Indo-Pacific’ (FOIP) strategy is to shape and consolidate regional order in the Indo-Pacific region based on the existing rules-based international order. The concept initially aimed to achieve two different objectives—shaping a regional order in the Indo-Pacific and ensuring the defence of Japan; however, Japan has gradually shifted its strategic focus onto the former, separating national defence from the FOIP concept, which reflects a change in the degree of its commitment to the two objectives. On the one hand, as its overall security strategy, Japan has determined to steadily enhance its national defence by increasing its own defence capabilities and strengthening the US–Japan alliance, while transforming its partnerships with like-minded states, such as Australia and India, into a diplomatic, and potentially military, alignment. This has been brought about by shifts in the regional balance of power, particularly the rise of China and the relative decline of the United States. On the other hand, as part of its FOIP strategy, Japan's attempts to build a new regional order in the Indo-Pacific region aim to defend the existing rules-based order established by the United States from challengers, particularly China. Yet, given the strategic uncertainty over Japan's international coalition-building efforts to create a new regional order, Japan has made its approach flexible; Tokyo is using its ambiguous FOIP concept to gauge other states' responses, understand their perspectives, and change its strategic emphases accordingly—so-called ‘tactical hedging’. Japan has pursued similar means to achieve the two key objectives. Nevertheless, the country's core interest, the defence of Japan, is more imperative than building a regional order in the Indo-Pacific region, and Japan faces different types of challenges in the future. Full Article
ring Supporting NHS Cybersecurity During COVID-19 is Vital By feedproxy.google.com Published On :: Thu, 02 Apr 2020 12:09:33 +0000 2 April 2020 Joyce Hakmeh Senior Research Fellow, International Security Programme; Co-Editor, Journal of Cyber Policy @joycehakmeh LinkedIn The current crisis is an opportunity for the UK government to show agility in how it deals with cyber threats and how it cooperates with the private sector in creating cyber resilience. 2020-04-02-NHS-nurse-tech-cyber Nurse uses a wireless electronic tablet to order medicines from the pharmacy at The Queen Elizabeth Hospital, Birmingham, England. Photo by Christopher Furlong/Getty Images. The World Health Organization, US Department of Health and Human Services, and hospitals in Spain, France and the Czech Republic have all suffered cyberattacks during the ongoing COVID-19 crisis.In the Czech Republic, a successful attack targeted a hospital with one of the country’s biggest COVID-19 testing laboratories, forcing its entire IT network to shut down, urgent surgical operations to be rescheduled, and patients to be moved to nearby hospitals. The attack also delayed dozens of COVID-19 test results and affected the hospital’s data transfer and storage, affecting the healthcare the hospital could provide.In the UK, the National Health Service (NHS) is already in crisis mode, focused on providing beds and ventilators to respond to one of the largest peacetime threats ever faced. But supporting the health sector goes beyond increasing human resources and equipment capacity.Health services ill-preparedCybersecurity support, both at organizational and individual level, is critical so health professionals can carry on saving lives, safely and securely. Yet this support is currently missing and the health services may be ill-prepared to deal with the aftermath of potential cyberattacks.When the NHS was hit by the Wannacry ransomware attack in 2017 - one of the largest cyberattacks the UK has witnessed to date – it caused massive disruption, with at least 80 of the 236 trusts across England affected and thousands of appointments and operations cancelled. Fortunately, a ‘kill-switch’ activated by a cybersecurity researcher quickly brought it to a halt.But the UK’s National Cyber Security Centre (NCSC), has been warning for some time against a cyber attack targeting national critical infrastructure sectors, including the health sector. A similar attack, known as category one (C1) attack, could cripple the UK with devastating consequences. It could happen and we should be prepared.Although the NHS has taken measures since Wannacry to improve cybersecurity, its enormous IT networks, legacy equipment and the overlap between the operational and information technology (OT/IT) does mean mitigating current potential threats are beyond its ability.And the threats have radically increased. More NHS staff with access to critical systems and patient health records are increasingly working remotely. The NHS has also extended its physical presence with new premises, such as the Nightingale hospital, potentially the largest temporary hospital in the world.Radical change frequently means proper cybersecurity protocols are not put in place. Even existing cybersecurity processes had to be side-stepped because of the outbreak, such as the decision by NHS Digital to delay its annual cybersecurity audit until September. During this audit, health and care organizations submit data security and protection toolkits to regulators setting out their cybersecurity and cyber resilience levels.The decision to delay was made to allow the NHS organizations to focus capacity on responding to COVID-19, but cybersecurity was highlighted as a high risk, and the importance of NHS and Social Care remaining resilient to cyberattacks was stressed.The NHS is stretched to breaking point. Expecting it to be on top of its cybersecurity during these exceptionally challenging times is unrealistic, and could actually add to the existing risk.Now is the time where new partnerships and support models should be emerging to support the NHS and help build its resilience. Now is the time where innovative public-private partnerships on cybersecurity should be formed.Similar to the economic package from the UK chancellor and innovative thinking on ventilator production, the government should oversee a scheme calling on the large cybersecurity capacity within the private sector to step in and assist the NHS. This support can be delivered in many different ways, but it must be mobilized swiftly.The NCSC for instance has led the formation of the Cyber Security Information Sharing Partnership (CiSP)— a joint industry and UK government initiative to exchange cyber threat information confidentially in real time with the aim of reducing the impact of cyberattacks on UK businesses.CiSP comprises organizations vetted by NCSC which go through a membership process before being able to join. These members could conduct cybersecurity assessment and penetration testing for NHS organizations, retrospectively assisting in implementing key security controls which may have been overlooked.They can also help by making sure NHS remote access systems are fully patched and advising on sensible security systems and approved solutions. They can identify critical OT and legacy systems and advise on their security.The NCSC should continue working with the NHS to enhance provision of public comprehensive guidance on cyber defence and response to potential attack. This would show they are on top of the situation, projecting confidence and reassurance.It is often said in every crisis lies an opportunity. This is an opportunity for the UK government to show agility in how it deals with cyber threats and how it cooperates with the private sector in creating cyber resilience.It is an opportunity to lead a much-needed cultural change showing cybersecurity should never be an afterthought. Full Article
ring Nuclear Tensions Must Not Be Sidelined During Coronavirus By feedproxy.google.com Published On :: Fri, 01 May 2020 11:18:35 +0000 1 May 2020 Ana Alecsandru Research Assistant, International Security Programme @anaalecs LinkedIn Although the pandemic means the Nuclear Non-Proliferation Treaty (NPT) Review Conference (RevCon) is postponed, the delay could be an opportunity to better the health of the NPT regime. 2020-05-01-Iran-Peace-Nuclear Painted stairs in Tehran, Iran symbolizing hope. Photo by Fatemeh Bahrami/Anadolu Agency/Getty Images. Despite face-to-face diplomatic meetings being increasingly rare during the current disruption, COVID-19 will ultimately force a redefinition of national security and defence spending priorities, and this could provide the possibility of an improved political climate at RevCon when it happens in 2021.With US presidential elections due in November and a gradual engagement growing between the EU and Iran, there could be a new context for more cooperation between states by 2021. Two key areas of focus over the coming months will be the arms control talks between the United States and Russia, and Iran’s compliance with the 2015 Joint Comprehensive Plan of Action (JCPOA), also known as the Iran Nuclear Deal.It is too early to discern the medium- and longer-term consequences of COVID-19 for defence ministries, but a greater focus on societal resilience and reinvigorating economic productivity will likely undercut the rationale for expensive nuclear modernization.Therefore, extending the current New START (Strategic Arms Reduction Treaty) would be the best, most practical option to give both Russia and the United States time to explore more ambitious multilateral arms control measures, while allowing their current focus to remain on the pandemic and economic relief.Continuing distrustBut with the current treaty — which limits nuclear warheads, missiles, bombers, and launchers — due to expire in February 2021, the continuing distrust between the United States and Russia makes this extension hard to achieve, and a follow-on treaty even less likely.Prospects for future bilateral negotiations are hindered by President Donald Trump’s vision for a trilateral arms control initiative involving both China and Russia. But China opposes this on the grounds that its nuclear arsenal is far smaller than that of the two others.While there appears to be agreement that the nuclear arsenals of China, France, and the UK (the NPT nuclear-weapons states) and those of the states outside the treaty (India, Pakistan, North Korea, and Israel) will all have to be taken into account going forward, a practical mechanism for doing so proves elusive.If Joe Biden wins the US presidency he seems likely to pursue an extension of the New START treaty and could also prevent a withdrawal from the Open Skies treaty, the latest arms control agreement targeted by the Trump administration.Under a Biden administration, the United States would also probably re-join the JCPOA, provided Tehran returned to strict compliance with the deal. Biden could even use the team that negotiated the Iran deal to advance the goal of denuclearization of the Korean peninsula.For an NPT regime already confronted by a series of longstanding divergences, it is essential that Iran remains a signatory especially as tensions between Iran and the United States have escalated recently — due to the Qassim Suleimani assassination and the recent claim by Iran’s Revolutionary Guard Corps to have successfully placed the country’s first military satellite into orbit.This announcement raised red flags among experts about whether Iran is developing intercontinental ballistic missiles due to the dual-use nature of space technology. The satellite launch — deeply troubling for Iran’s neighbours and the EU countries — may strengthen the US argument that it is a cover for the development of ballistic missiles capable of delivering nuclear weapons.However, as with many other countries, Iran is struggling with a severe coronavirus crisis and will be pouring its scientific expertise and funds into that rather than other efforts — including the nuclear programme.Those European countries supporting the trading mechanism INSTEX (Instrument in Support of Trade Exchanges) for sending humanitarian goods into Iran could use this crisis to encourage Iran to remain in compliance with the JCPOA and its NPT obligations.France, Germany and the UK (the E3) have already successfully concluded the first transaction, which was to facilitate the export of medical goods from Europe to Iran. But the recent Iranian escalatory steps will most certainly place a strain on the preservation of this arrangement.COVID-19 might have delayed Iran’s next breach of the 2015 nuclear agreement but Tehran will inevitably seek to strengthen its hand before any potential negotiations with the United States after the presidential elections.As frosty US-Iranian relations — exacerbated by the coronavirus pandemic — prevent diplomatic negotiations, this constructive engagement between the E3 and Iran might prove instrumental in reviving the JCPOA and ensuring Iran stays committed to both nuclear non-proliferation and disarmament.While countries focus their efforts on tackling the coronavirus pandemic, it is understandable resources may be limited for other global challenges, such as the increasing risk of nuclear weapons use across several regions.But the potential ramifications of the COVID-19 crisis for the NPT regime are profound. Ongoing tensions between the nuclear-armed states must not be ignored while the world’s focus is elsewhere, and the nuclear community should continue to work together to progress nuclear non-proliferation and disarmament, building bridges of cooperation and trust that can long outlast the pandemic. Full Article
ring Politics, policy-making and the presence of images of suffering children By feedproxy.google.com Published On :: Thu, 07 May 2020 08:45:52 +0000 7 May 2020 , Volume 96, Number 3 Helen Berents Read Online In 2017 Trump expressed pity for the ‘beautiful babies’ killed in a gas attack on Khan Shaykhun in Syria before launching airstrikes against President Assad's regime. Images of suffering children in world politics are often used as a synecdoche for a broader conflict or disaster. Injured, suffering, or dead; the ways in which images of children circulate in global public discourse must be critically examined to uncover the assumptions that operate in these environments. This article explores reactions to images of children by representatives and leaders of states to trace the interconnected affective and political dimensions of these images. In contrast to attending to the expected empathetic responses prompted by images of children, this article particularly focuses on when such images prompt bellicose foreign policy decision-making. In doing this, the article forwards a way of thinking about images as contentious affective objects in international relations. The ways in which images of children's bodies and suffering are strategically deployed by politicians deserves closer scrutiny to uncover the visual politics of childhood inherent in these moments of international politics and policy-making. Full Article
ring Activists and Entrepreneurs: The Future of the Arab Spring By feedproxy.google.com Published On :: Tue, 27 May 2014 15:00:01 +0000 Research Event 10 June 2014 - 2:30pm to 4:00pm Chatham House, London Event participants Maryam Jamshidi, Author, The Future of the Arab Spring: Civic Entrepreneurship in Politics, Art, and Technology StartupsChair: Leonie Northedge, Research Associate, Middle East and North Africa Programme, Chatham House Three years on from the Arab uprisings, many of the goals of the protests remain unmet. However, the spirit of collaboration which was nurtured during this time lives on and has resulted in an expansion of grassroots organizations, tech startups and artists’ collectives. At this roundtable, Maryam Jamshidi, author of The Future of the Arab Spring: Civic Entrepreneurship in Politics, Art, and Technology Startups, will argue that the Middle East’s ‘civic entrepreneurs’ continue to apply their talents to rebuilding their countries’ political, economic and social fabrics.THIS EVENT IS NOW FULL AND REGISTRATION IS CLOSED. Department/project Middle East and North Africa Programme Full Article
ring Thematic review series: Brain Lipids. Cholesterol metabolism in the central nervous system during early development and in the mature animal By feedproxy.google.com Published On :: 2004-08-01 John M. DietschyAug 1, 2004; 45:1375-1397Thematic Reviews Full Article
ring Lipid rafts: bringing order to chaos By feedproxy.google.com Published On :: 2003-04-01 Linda J. PikeApr 1, 2003; 44:655-667Thematic Reviews Full Article
ring Exploring the Obstacles and Opportunities for Expanded UK-Latin American Trade and Investment By feedproxy.google.com Published On :: Thu, 27 Feb 2020 12:40:01 +0000 Invitation Only Research Event 14 January 2020 - 8:30am to 11:00am Chatham House | 10 St James's Square | London | SW1Y 4LE Trade and investment between the UK and Latin America is woefully underdeveloped. Latin America’s agricultural powerhouses Brazil and Argentina only accounted for a total of 1.6% of the UK’s agricultural market across eight sectors in 2018, all of those areas in which Argentina and Brazil have substantial comparative advantages. Conversely, UK exports to the large Latin American economies remain far below their potential. To cite a few examples, in 2018 in the electrical equipment sector, the UK only exported $95.7 million of those products to Brazil, making the ninth largest economy in the world only the 42nd export market for those goods from the UK; Mexico only imported $91.4 million of UK-made electrical goods, placing it directly behind Brazil as UK’s market for those goods.As we look to the future, any improvement to the relationship will depend on two factors: 1) how the UK leaves the EU and 2) whether Latin American agricultural producers can improve their environmental practices and can meet the production standards established by the EU and likely maintained by a potential post-Brexit Britain.In the first meeting of the working group, Chatham House convened a range of policymakers, practitioners and academics to explore this topic in depth, identify the key issues driving this trend, and begin to consider how improvements might best be made. Subsequent meetings will focus on specific sectors in commerce and investment.We would like to thank BTG Pactual, Cairn Energy plc, Diageo, Equinor, Fresnillo Management Services, HSBC Holdings plc and Wintershall Dea for their generous support of the Latin America Initiative. Event attributes Chatham House Rule Department/project US and the Americas Programme, Latin America Initiative US and Americas Programme Email Full Article
ring Nuclear Tensions Must Not Be Sidelined During Coronavirus By feedproxy.google.com Published On :: Fri, 01 May 2020 11:18:35 +0000 1 May 2020 Ana Alecsandru Research Assistant, International Security Programme @anaalecs LinkedIn Although the pandemic means the Nuclear Non-Proliferation Treaty (NPT) Review Conference (RevCon) is postponed, the delay could be an opportunity to better the health of the NPT regime. 2020-05-01-Iran-Peace-Nuclear Painted stairs in Tehran, Iran symbolizing hope. Photo by Fatemeh Bahrami/Anadolu Agency/Getty Images. Despite face-to-face diplomatic meetings being increasingly rare during the current disruption, COVID-19 will ultimately force a redefinition of national security and defence spending priorities, and this could provide the possibility of an improved political climate at RevCon when it happens in 2021.With US presidential elections due in November and a gradual engagement growing between the EU and Iran, there could be a new context for more cooperation between states by 2021. Two key areas of focus over the coming months will be the arms control talks between the United States and Russia, and Iran’s compliance with the 2015 Joint Comprehensive Plan of Action (JCPOA), also known as the Iran Nuclear Deal.It is too early to discern the medium- and longer-term consequences of COVID-19 for defence ministries, but a greater focus on societal resilience and reinvigorating economic productivity will likely undercut the rationale for expensive nuclear modernization.Therefore, extending the current New START (Strategic Arms Reduction Treaty) would be the best, most practical option to give both Russia and the United States time to explore more ambitious multilateral arms control measures, while allowing their current focus to remain on the pandemic and economic relief.Continuing distrustBut with the current treaty — which limits nuclear warheads, missiles, bombers, and launchers — due to expire in February 2021, the continuing distrust between the United States and Russia makes this extension hard to achieve, and a follow-on treaty even less likely.Prospects for future bilateral negotiations are hindered by President Donald Trump’s vision for a trilateral arms control initiative involving both China and Russia. But China opposes this on the grounds that its nuclear arsenal is far smaller than that of the two others.While there appears to be agreement that the nuclear arsenals of China, France, and the UK (the NPT nuclear-weapons states) and those of the states outside the treaty (India, Pakistan, North Korea, and Israel) will all have to be taken into account going forward, a practical mechanism for doing so proves elusive.If Joe Biden wins the US presidency he seems likely to pursue an extension of the New START treaty and could also prevent a withdrawal from the Open Skies treaty, the latest arms control agreement targeted by the Trump administration.Under a Biden administration, the United States would also probably re-join the JCPOA, provided Tehran returned to strict compliance with the deal. Biden could even use the team that negotiated the Iran deal to advance the goal of denuclearization of the Korean peninsula.For an NPT regime already confronted by a series of longstanding divergences, it is essential that Iran remains a signatory especially as tensions between Iran and the United States have escalated recently — due to the Qassim Suleimani assassination and the recent claim by Iran’s Revolutionary Guard Corps to have successfully placed the country’s first military satellite into orbit.This announcement raised red flags among experts about whether Iran is developing intercontinental ballistic missiles due to the dual-use nature of space technology. The satellite launch — deeply troubling for Iran’s neighbours and the EU countries — may strengthen the US argument that it is a cover for the development of ballistic missiles capable of delivering nuclear weapons.However, as with many other countries, Iran is struggling with a severe coronavirus crisis and will be pouring its scientific expertise and funds into that rather than other efforts — including the nuclear programme.Those European countries supporting the trading mechanism INSTEX (Instrument in Support of Trade Exchanges) for sending humanitarian goods into Iran could use this crisis to encourage Iran to remain in compliance with the JCPOA and its NPT obligations.France, Germany and the UK (the E3) have already successfully concluded the first transaction, which was to facilitate the export of medical goods from Europe to Iran. But the recent Iranian escalatory steps will most certainly place a strain on the preservation of this arrangement.COVID-19 might have delayed Iran’s next breach of the 2015 nuclear agreement but Tehran will inevitably seek to strengthen its hand before any potential negotiations with the United States after the presidential elections.As frosty US-Iranian relations — exacerbated by the coronavirus pandemic — prevent diplomatic negotiations, this constructive engagement between the E3 and Iran might prove instrumental in reviving the JCPOA and ensuring Iran stays committed to both nuclear non-proliferation and disarmament.While countries focus their efforts on tackling the coronavirus pandemic, it is understandable resources may be limited for other global challenges, such as the increasing risk of nuclear weapons use across several regions.But the potential ramifications of the COVID-19 crisis for the NPT regime are profound. Ongoing tensions between the nuclear-armed states must not be ignored while the world’s focus is elsewhere, and the nuclear community should continue to work together to progress nuclear non-proliferation and disarmament, building bridges of cooperation and trust that can long outlast the pandemic. Full Article
ring A kinesin adapter directly mediates dendritic mRNA localization during neural development in mice [Neurobiology] By feedproxy.google.com Published On :: 2020-05-08T03:41:14-07:00 Motor protein-based active transport is essential for mRNA localization and local translation in animal cells, yet how mRNA granules interact with motor proteins remains poorly understood. Using an unbiased yeast two–hybrid screen for interactions between murine RNA-binding proteins (RBPs) and motor proteins, here we identified protein interaction with APP tail-1 (PAT1) as a potential direct adapter between zipcode-binding protein 1 (ZBP1, a β-actin RBP) and the kinesin-I motor complex. The amino acid sequence of mouse PAT1 is similar to that of the kinesin light chain (KLC), and we found that PAT1 binds to KLC directly. Studying PAT1 in mouse primary hippocampal neuronal cultures from both sexes and using structured illumination microscopic imaging of these neurons, we observed that brain-derived neurotrophic factor (BDNF) enhances co-localization of dendritic ZBP1 and PAT1 within granules that also contain kinesin-I. PAT1 is essential for BDNF-stimulated neuronal growth cone development and dendritic protrusion formation, and we noted that ZBP1 and PAT1 co-locate along with β-actin mRNA in actively transported granules in living neurons. Acute disruption of the PAT1–ZBP1 interaction in neurons with PAT1 siRNA or a dominant-negative ZBP1 construct diminished localization of β-actin mRNA but not of Ca2+/calmodulin-dependent protein kinase IIα (CaMKIIα) mRNA in dendrites. The aberrant β-actin mRNA localization resulted in abnormal dendritic protrusions and growth cone dynamics. These results suggest a critical role for PAT1 in BDNF-induced β-actin mRNA transport during postnatal development and reveal a new molecular mechanism for mRNA localization in vertebrates. Full Article
ring Neil Shearing By feedproxy.google.com Published On :: Wed, 29 Apr 2020 18:45:16 +0000 Associate Fellow, Global Economy and Finance Programme Biography Neil Shearing is group chief economist at Capital Economics, the leading economic research company. He heads a team of 70 economists spread across Europe, the Americas and Asia, and is responsible for driving the firm’s research agenda as well as developing its products and relationships with clients. He is also a director of the company.Neil has 20 years’ experience as a macroeconomist, built in both the government and financial sector. He presents regularly on the global economic and financial market outlook and is a well-known voice within the investment community, having worked in both London and New York.Neil has written articles in the Financial Times and a number of other newspapers, as well as appearing regularly on TV and radio.Prior to becoming group chief economist, Neil was chief emerging markets economist at Capital Economics, managing a team that won several awards for forecast accuracy. He also managed the New York office.Neil joined Capital Economics from HM Treasury where he worked as an economic adviser in various areas, including fiscal policy and global economics.He holds degrees in Economics from the University of York and the University of London and is a fellow of the Royal Society of Arts.Neil's main area of research interest is in analysing and understanding structural shifts in the global economy. This clearly touches on a wide range of issues, but a fundamental question today is whether we’re facing the end of globalisation, a key area of current work which raises several interesting questions.What does history tell us about past waves of globalisation? Are they doomed to end? What role is technology playing? Could new technologies drive another wave of integration or are they more likely to lead to re-shoring as robots replace workers? Which countries would be most vulnerable to a rollback of globalisation? Related to this, will emerging economies ever 'catch up' to income levels in developed economies? What are the implications for policy makers (governments, central banks) and global institutions (IMF, World Bank)? Areas of expertise Global economyEmerging markets (China, Latin America, Central & Eastern Europe)Monetary economicsGlobal trade and capital flows Full Article
ring Nuclear Tensions Must Not Be Sidelined During Coronavirus By feedproxy.google.com Published On :: Fri, 01 May 2020 11:18:35 +0000 1 May 2020 Ana Alecsandru Research Assistant, International Security Programme @anaalecs LinkedIn Although the pandemic means the Nuclear Non-Proliferation Treaty (NPT) Review Conference (RevCon) is postponed, the delay could be an opportunity to better the health of the NPT regime. 2020-05-01-Iran-Peace-Nuclear Painted stairs in Tehran, Iran symbolizing hope. Photo by Fatemeh Bahrami/Anadolu Agency/Getty Images. Despite face-to-face diplomatic meetings being increasingly rare during the current disruption, COVID-19 will ultimately force a redefinition of national security and defence spending priorities, and this could provide the possibility of an improved political climate at RevCon when it happens in 2021.With US presidential elections due in November and a gradual engagement growing between the EU and Iran, there could be a new context for more cooperation between states by 2021. Two key areas of focus over the coming months will be the arms control talks between the United States and Russia, and Iran’s compliance with the 2015 Joint Comprehensive Plan of Action (JCPOA), also known as the Iran Nuclear Deal.It is too early to discern the medium- and longer-term consequences of COVID-19 for defence ministries, but a greater focus on societal resilience and reinvigorating economic productivity will likely undercut the rationale for expensive nuclear modernization.Therefore, extending the current New START (Strategic Arms Reduction Treaty) would be the best, most practical option to give both Russia and the United States time to explore more ambitious multilateral arms control measures, while allowing their current focus to remain on the pandemic and economic relief.Continuing distrustBut with the current treaty — which limits nuclear warheads, missiles, bombers, and launchers — due to expire in February 2021, the continuing distrust between the United States and Russia makes this extension hard to achieve, and a follow-on treaty even less likely.Prospects for future bilateral negotiations are hindered by President Donald Trump’s vision for a trilateral arms control initiative involving both China and Russia. But China opposes this on the grounds that its nuclear arsenal is far smaller than that of the two others.While there appears to be agreement that the nuclear arsenals of China, France, and the UK (the NPT nuclear-weapons states) and those of the states outside the treaty (India, Pakistan, North Korea, and Israel) will all have to be taken into account going forward, a practical mechanism for doing so proves elusive.If Joe Biden wins the US presidency he seems likely to pursue an extension of the New START treaty and could also prevent a withdrawal from the Open Skies treaty, the latest arms control agreement targeted by the Trump administration.Under a Biden administration, the United States would also probably re-join the JCPOA, provided Tehran returned to strict compliance with the deal. Biden could even use the team that negotiated the Iran deal to advance the goal of denuclearization of the Korean peninsula.For an NPT regime already confronted by a series of longstanding divergences, it is essential that Iran remains a signatory especially as tensions between Iran and the United States have escalated recently — due to the Qassim Suleimani assassination and the recent claim by Iran’s Revolutionary Guard Corps to have successfully placed the country’s first military satellite into orbit.This announcement raised red flags among experts about whether Iran is developing intercontinental ballistic missiles due to the dual-use nature of space technology. The satellite launch — deeply troubling for Iran’s neighbours and the EU countries — may strengthen the US argument that it is a cover for the development of ballistic missiles capable of delivering nuclear weapons.However, as with many other countries, Iran is struggling with a severe coronavirus crisis and will be pouring its scientific expertise and funds into that rather than other efforts — including the nuclear programme.Those European countries supporting the trading mechanism INSTEX (Instrument in Support of Trade Exchanges) for sending humanitarian goods into Iran could use this crisis to encourage Iran to remain in compliance with the JCPOA and its NPT obligations.France, Germany and the UK (the E3) have already successfully concluded the first transaction, which was to facilitate the export of medical goods from Europe to Iran. But the recent Iranian escalatory steps will most certainly place a strain on the preservation of this arrangement.COVID-19 might have delayed Iran’s next breach of the 2015 nuclear agreement but Tehran will inevitably seek to strengthen its hand before any potential negotiations with the United States after the presidential elections.As frosty US-Iranian relations — exacerbated by the coronavirus pandemic — prevent diplomatic negotiations, this constructive engagement between the E3 and Iran might prove instrumental in reviving the JCPOA and ensuring Iran stays committed to both nuclear non-proliferation and disarmament.While countries focus their efforts on tackling the coronavirus pandemic, it is understandable resources may be limited for other global challenges, such as the increasing risk of nuclear weapons use across several regions.But the potential ramifications of the COVID-19 crisis for the NPT regime are profound. Ongoing tensions between the nuclear-armed states must not be ignored while the world’s focus is elsewhere, and the nuclear community should continue to work together to progress nuclear non-proliferation and disarmament, building bridges of cooperation and trust that can long outlast the pandemic. Full Article
ring Politics, policy-making and the presence of images of suffering children By feedproxy.google.com Published On :: Thu, 07 May 2020 08:45:52 +0000 7 May 2020 , Volume 96, Number 3 Helen Berents Read Online In 2017 Trump expressed pity for the ‘beautiful babies’ killed in a gas attack on Khan Shaykhun in Syria before launching airstrikes against President Assad's regime. Images of suffering children in world politics are often used as a synecdoche for a broader conflict or disaster. Injured, suffering, or dead; the ways in which images of children circulate in global public discourse must be critically examined to uncover the assumptions that operate in these environments. This article explores reactions to images of children by representatives and leaders of states to trace the interconnected affective and political dimensions of these images. In contrast to attending to the expected empathetic responses prompted by images of children, this article particularly focuses on when such images prompt bellicose foreign policy decision-making. In doing this, the article forwards a way of thinking about images as contentious affective objects in international relations. The ways in which images of children's bodies and suffering are strategically deployed by politicians deserves closer scrutiny to uncover the visual politics of childhood inherent in these moments of international politics and policy-making. Full Article
ring Restructuring the European State By feedproxy.google.com Published On :: Wed, 07 Mar 2018 00:00:00 +0000 Full Article
ring Leaders Who Lunch: Robert Barrington By feedproxy.google.com Published On :: Thu, 10 May 2018 00:00:00 +0100 Full Article