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Covid-19 claims second Cape nurse

A Tygerberg Hospital nurse has become the latest health-care worker to die of Covid-19 as the Western Cape saw an increase of 11 coronavirus deaths and more than 500 new infections.




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Corona: Why Researchers Fear a Second Wave

Germany’s strict limitations on contact between people haven't conquered the virus - they have merely bought the country more time. Epidemiologists believe a second wave will come.





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Covid-19 claims second Cape nurse

Cape Town - A Tygerberg Hospital nurse has become the latest health-care worker to die of Covid-19 as the Western Cape saw an increase of 11 coronavirus deaths and more than 500 new infections on Friday. “We are deeply saddened to announce the death of a Tygerberg Hospital nurse, Ntombizakithi Ngidi,” said Premier Alan Winde. “We extend our deepest condolences to her family, friends and her colleagues at this time and we honour her service to the people of this province.” Ngidi is the second nurse to die from Covid-19 in the...




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US lifts the Cuba secondary sanctions waiver

The United States (“US”) Government announced on 17 April 2019 that it would not renew a waiver to Title III of the US Helms-Burton Act 1996 (“Title III”) that had effectively prevented former owners of property confiscated f...




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‘Fortnite’ Party Royale Will Become ‘Second Life’ On Its Way To Being The Metaverse

Fortnite will become Second Life before it becomes the Metaverse. And it's getting extremely close. ......




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Enjoy every second of the play-off semi-final win over Brighton today

Crystal Palace went into the second leg of the play-off semi-final against Brighton & Hove Albion without the Championship's top scorer, Glenn Murray. Murray had found the back of the net 30 times...




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Second Group of Russian Servicemen Helping Italy to Fight Coronavirus Heading Back Home

Moscow sent over a dozen military transport planes with equipment and specialists to Italy back in March to help the country in its efforts to stop the spread of the COVID-19 infection. ......




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At Estonia’s initiative, 80 countries across the world discussed lessons for peace from the Second World War and the current security situation

Yesterday 8 May, the largest high-level gathering of UN member states since the beginning of the COVID-19 crisis was held as part of Estonia's presidency of the UN Security Council. The six-hour meeting brought together nearly 80 countries, around 50 of which were represented at a ministerial level, to exchange thoughts on lessons learnt from the Second World War. All the Security Council members were represented, with almost half attending with high-level participants: Germany, France, Belgium, Vietnam, United States and the United Kingdom in addition to Estonia. 'Yesterday's meeting was the largest international event to mark the 75th anniversary of the Second World War in Europe. It...




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Aizanoi, the second Ephesus of Turkey

Aizanoi, located in the western province of Kütahya’s Çavdarhisar district and on the UNESCO Tentative List of World Heritage, is home to the best-protected temple in Anatolia: The Temple of Zeus. (Photos: Alamy)




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World's second deepest canyon attracts visitors

World's second deepest canyon located in Turkey's Black Sea province of Kastamonu attracts visitors. (Source: Anadolu Agency)




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Syrian man vandalizes Amsterdam kosher restaurant for second time


The attack was the fifth case of vandalism or intimidation in 2 ½ years.




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Warning Of A Second Pandemic Wave, Health Minister Says Iran Needs A CDC

While admitting that the official death toll from the coronavirus outbreak in Iran has exceeded 6,000, the Islamic Republic Minister of Health warned of a heavy second wave of the disease next autumn and winter. ";A relatively heavy attack by a combination of flu and coronavirus is expected in the fall and winter";, the Minister, Saeed Namaki, reiterated.




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Second wave a worry, warn advisers

The nation must be ready to cope with a possible resurgence in Covid-19 cases if lockdown measures are eased, as expected, starting on May 17, the government's pandemic advisory committee warned on Friday.




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Second case of bird flu discovered in Pardubice area

Prague Daily Monitor

A second case of bird flu was discovered in Pardubice area at a commercial chicken farm, the spokesperson for the Minister of Agriculture Vojtěch Bílý communicated the news to ČTK. The first case in three years was discovered this year in January at a farm in small farm in the Žďár area. The Ministry is still analyzing the situation and will hold a press conference which will include the Minister of Agriculture and the Director of the Czech Veterinary Office.

read more




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France star suffers calf knock in second Barca training session

The 26-year-old joined Barca from Lyon in 2016.




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'The greatest challenge': Asia catches coronavirus' second wave

Beijing has imposed new restrictions on an upscale diplomats district home to 3.5 million people, as it guards a second wave of coronavirus cases.




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Sonam Kapoor receives love, prayers on her second wedding anniversary

Anil Kapoor wrote, "May you be blessed with all the love & happiness, just as we feel blessed to have you in our lives."




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Coronavirus latest: Italy second European country to reach 30k COVID-19 deaths

1




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Second White House worker tests positive for coronavirus

A second White House worker this week has tested positive for coronavirus, officials said Friday, even as President Donald Trump continued to go mask-free at a World War II commemoration with veterans in their 90s.




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Home sales expected to rise 26 per cent in second half of 2014: Knight Frank

After a lacklustre first half, home sales across the top six cities in the country are expected to rise 26 per cent in the second half of 2014 compared to a year ago, according to a research report by property advisory firm Knight Frank. A negative sentiment among home buyers due to the slow economy, high interest rates, inflation and also political uncertainty had tempered home sales in the first half of the year. While new launches in the period dropped 32 per cent, sales volume was down 27 per cent. But now, with a positive election result, a stable government at the centre and sops for the housing sector […]




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MOST150 Technology to Control the Infotainment System on Volvo Cars’ Second-Generation XC60 SUV

MOST150 Technology to Control the Infotainment System on Volvo Cars’ Second-Generation XC60 SUV




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Social Protection Support Project (Second Additional Financing)

Approved project 43407-017 in Philippines.




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3353-VIE: The Second Greater Mekong Subregion (GMS) Corridor Towns Development Project [Package SP2]




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SRI: Second Integrated Road Investment Program




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Loan No. 50301-SRI: Second Integrated Road Investment Program [RDA/ADB/iROAD-2(UVA)/NCB]




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Secondhand Smoke Blocks Artery Repair

Title: Secondhand Smoke Blocks Artery Repair
Category: Health News
Created: 4/30/2008 2:00:00 AM
Last Editorial Review: 4/30/2008 12:00:00 AM




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Secondhand Smoke Permeates Many Apartment Buildings: Study

Title: Secondhand Smoke Permeates Many Apartment Buildings: Study
Category: Health News
Created: 4/29/2012 10:05:00 AM
Last Editorial Review: 4/30/2012 12:00:00 AM




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Many Asthmatic Kids Harmed by Secondhand Smoke: Study

Title: Many Asthmatic Kids Harmed by Secondhand Smoke: Study
Category: Health News
Created: 5/1/2012 10:05:00 AM
Last Editorial Review: 5/1/2012 12:00:00 AM




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Second Man Arrested in Tainted Letter Case, Officials Report

Title: Second Man Arrested in Tainted Letter Case, Officials Report
Category: Health News
Created: 4/27/2013 6:35:00 PM
Last Editorial Review: 4/29/2013 12:00:00 AM




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Secondhand Smoke Tied to Lower 'Good' Cholesterol in Teen Girls

Title: Secondhand Smoke Tied to Lower 'Good' Cholesterol in Teen Girls
Category: Health News
Created: 4/30/2013 2:35:00 PM
Last Editorial Review: 5/1/2013 12:00:00 AM




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Necklace Spots A-Fib in Just Over 30 Seconds

Title: Necklace Spots A-Fib in Just Over 30 Seconds
Category: Health News
Created: 5/6/2020 12:00:00 AM
Last Editorial Review: 5/7/2020 12:00:00 AM




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Necklace Spots A-Fib in Just Over 30 Seconds

A necklace outfitted with a high-tech pendant may be able to screen for signs of an abnormal heart rhythm condition known as atrial fibrillation.




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Second HIV Patient Reportedly 'Cured'

Title: Second HIV Patient Reportedly 'Cured'
Category: Health News
Created: 3/9/2020 12:00:00 AM
Last Editorial Review: 3/10/2020 12:00:00 AM




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Secondary osteon structural heterogeneity between the cranial and caudal cortices of the proximal humerus in white-tailed deer [RESEARCH ARTICLE]

Jack Nguyen and Meir M. Barak

Cortical bone remodeling is an ongoing process triggered by microdamage, where osteoclasts resorb existing bone and osteoblasts deposit new bone in the form of secondary osteons (Haversian systems). Previous studies revealed regional variance in Haversian systems structure and possibly material, between opposite cortices of the same bone. As bone mechanical properties depend on tissue structure and material, it is predicted that bone mechanical properties will vary in accordance with structural and material regional heterogeneity. To test this hypothesis, we analyzed the structure, mineral content and compressive stiffness of secondary bone from the cranial and caudal cortices of the white-tailed deer proximal humerus. We found significantly larger Haversian systems and canals in the cranial cortex but no significant difference in mineral content between the two cortices. Accordingly, we found no difference in compressive stiffness between the two cortices and thus our working hypothesis was rejected. Seeing that the deer humerus is curved and thus likely subjected to bending during habitual locomotion, we expect that similar to other curved long bones, the cranial cortex of the deer humerus is likely subjected primarily to tensile strains and the caudal cortex is likely subject primarily to compressive strains. Consequently, our results suggest that strain magnitude (larger in compression) and sign (compression vs. tension) affect differently the osteoclasts and osteoblasts in the BMU. Our results further suggest that osteoclasts are inhibited in regions of high compressive strains (creating smaller Haversian systems) while osteoblasts’ osteoid deposition and mineralization is not affected by strain magnitude and sign.




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Renal, Cardiovascular, and Safety Outcomes of Canagliflozin by Baseline Kidney Function: A Secondary Analysis of the CREDENCE Randomized Trial

Background

Canagliflozin reduced renal and cardiovascular events in people with type 2 diabetes in the CREDENCE trial. We assessed efficacy and safety of canagliflozin by initial estimated glomerular filtration rate (eGFR).

Methods

CREDENCE randomly assigned 4401 participants with an eGFR of 30 to <90 ml/min per 1.73 m2 and substantial albuminuria to canagliflozin 100 mg or placebo. We used Cox proportional hazards regression to analyze effects on renal and cardiovascular efficacy and safety outcomes within screening eGFR subgroups (30 to <45, 45 to <60, and 60 to <90 ml/min per 1.73 m2) and linear mixed effects models to analyze the effects on eGFR slope.

Results

At screening, 1313 (30%), 1279 (29%), and 1809 (41%) participants had an eGFR of 30 to <45, 45 to <60, and 60 to <90 ml/min per 1.73 m2, respectively. The relative benefits of canagliflozin for renal and cardiovascular outcomes appeared consistent among eGFR subgroups (all P interaction >0.11). Subgroups with lower eGFRs, who were at greater risk, exhibited larger absolute benefits for renal outcomes. Canagliflozin’s lack of effect on serious adverse events, amputations, and fractures appeared consistent among eGFR subgroups. In all subgroups, canagliflozin use led to an acute eGFR drop followed by relative stabilization of eGFR loss. Among those with an eGFR of 30 to <45 ml/min per 1.73 m2, canagliflozin led to an initial drop of 2.03 ml/min per 1.73 m2. Thereafter, decline in eGFR was slower in the canagliflozin versus placebo group (–1.72 versus –4.33 ml/min per 1.73 m2; between-group difference 2.61 ml/min per 1.73 m2).

Conclusions

Canagliflozin safely reduced the risk of renal and cardiovascular events, with consistent results across eGFR subgroups, including the subgroup initiating treatment with an eGFR of 30 to <45 ml/min per 1.73 m2. Absolute benefits for renal outcomes were greatest in subgroups with lower eGFR.

Clinical Trial registry name and registration number

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy (CREDENCE), NCT02065791.




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Intravenous Iron Dosing and Infection Risk in Patients on Hemodialysis: A Prespecified Secondary Analysis of the PIVOTAL Trial

Background

Experimental and observational studies have raised concerns that giving intravenous (IV) iron to patients, such as individuals receiving maintenance hemodialysis, might increase the risk of infections. The Proactive IV Iron Therapy in Haemodialysis Patients (PIVOTAL) trial randomized 2141 patients undergoing maintenance hemodialysis for ESKD to a high-dose or a low-dose IV iron regimen, with a primary composite outcome of all-cause death, heart attack, stroke, or hospitalization for heart failure. Comparison of infection rates between the two groups was a prespecified secondary analysis.

Methods

Secondary end points included any infection, hospitalization for infection, and death from infection; we calculated cumulative event rates for these end points. We also interrogated the interaction between iron dose and vascular access (fistula versus catheter).

Results

We found no significant difference between the high-dose IV iron group compared with the lose-dose group in event rates for all infections (46.5% versus 45.5%, respectively, which represented incidences of 63.3 versus 69.4 per 100 patient years, respectively); rates of hospitalization for infection (29.6% versus 29.3%, respectively) also did not differ. We did find a significant association between risk of a first cardiovascular event and any infection in the previous 30 days. Compared with patients undergoing dialysis with an arteriovenous fistula, those doing so via a catheter had a higher incidence of having any infection, hospitalization for infection, or fatal infection, but IV iron dosing had no effect on these outcomes.

Conclusions

The high-dose and low-dose IV iron groups exhibited identical infection rates. Risk of a first cardiovascular event strongly associated with a recent infection.




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Shared decision making about blood tests: secondary analysis of video-recorded primary care consultations

BackgroundAwareness of the importance of shared decision making (SDM) is widespread; however, little research has focused on discussions surrounding investigations, despite increasing laboratory testing in primary care.AimTo explore the discussion of blood tests in routine primary care consultations.Design and settingA secondary analysis of 50 video-recorded routine primary care consultations, linked surveys, and records data (all from the One in a Million [OiaM] archive). The consultations were taken by 22 GPs across 12 practices.MethodA coding scheme was developed, using qualitative content analysis, to explore discussion of blood tests in transcripts of recorded consultations. Codes focused on instigating testing, the extent of SDM, and how results were explained. Survey data were used to compare patients’ pre-visit expectations with consultation content. Medical records were reviewed to compare tests discussed with those ordered.ResultsIn 36 out of 50 consultations that discussed ordering blood tests, 11 patients (31%) hinted that they wanted a blood test; however, none asked explicitly. Only four patients (11%) were offered alternative options. In 29 cases (81%) the GP gave some explanation of the indication, but only in six cases (17%) were the limitations of testing explained. Only 10 out of 31 patients (32%) were informed about all blood tests ordered. Of the 23 out of 50 consultations in which results were conveyed, the GP gave no explanation of the results in six cases (26%). Thirteen patients (57%) were only informed of an assessment of the results (for example, ‘normal’), rather than the actual results.ConclusionA lack of information dissemination and SDM exists around ordering tests and conveying results. Promoting SDM could reduce unnecessary testing and improve patient-centred care.




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Design of the {beta}3-Adrenergic Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure Trial

Combined pre-and post-capillary hypertension (CpcPH) is a relatively common complication of heart failure (HF) associated with a poor prognosis. Currently, there is no specific therapy approved for this entity. Recently, treatment with beta-3 adrenergic receptor (β3AR) agonists was able to improve pulmonary hemodynamics and right ventricular (RV) performance in a translational, large animal model of chronic PH. The authors present the design of a phase II randomized clinical trial that tests the benefits of mirabegron (a clinically available β3AR agonist) in patients with CpcPH due to HF. The effect of β3AR treatment will be evaluated on pulmonary hemodynamics, as well as clinical, biochemical, and advanced cardiac imaging parameters. (Beta3 Agonist Treatment in Chronic Pulmonary Hypertension Secondary to Heart Failure [SPHERE-HF]; NCT02775539)




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FPS Second Extinction Announced for Xbox Series X, Xbox One and PC

Developer Systemic Reaction has announced three-player, online cooperative shooter, Second Extinction, for the Xbox Series X, Xbox One and Windows PC via Steam.

"I’m very proud of what our team has created," said Systemic Reaction managing director Tobias Andersson. "As a live game, we plan to support Second Extinction long-term, as we do with all our titles. We can’t wait for players to team up, start playing, and become part of our community."

Lead producer Brynley Gibson added, "Second Extinction is a real passion project for our tight-knit team, and we’re just getting started. It’s incredible how far we’ve come in this short time, and I’m super excited to reveal more details, including our live roadmap, in the coming months."

View the announcement trailer below:

Here is an overview of the game:

Second Extinction is an intense three-player cooperative shooter, where your goal is to wipe out the mutated dinosaurs that have taken over the planet. Teamwork is  vital as you adopt the role of one of the survivors, using a unique combination of  weapons, abilities and skills to take on the vast number of enemies. Fight through  a maelstrom of bullets, bombs, teeth, claws and gore, it’s up to you to reclaim  Earth!

Key Features:

  • Intense Three-Player Co-Op – Earth is overrun by mutated dinosaurs! Team up with up to two other resistance fighters to take it back in short but intense combat operations.
  • Battle Mutated Monstrosities – These dinos are nothing like the ones in your history books! From electric raptors  to behemoth T-Rexes that tower over the horizon, these deadly creatures have evolved into the ultimate killing machines.
  • Experience Spectacular Action – Combine your fireteam’s unique weapons and abilities for explosive results  against overwhelming opposition in challenging combat set pieces.
  • Take Part in a Joint Effort – Your actions, together with the rest of the community, will shape the course of  the war against the dinosaurs.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443423/fps-second-extinction-announced-for-xbox-series-x-xbox-one-and-pc/




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Second NY Child Dies From Rare Syndrome Linked to COVID-19

Lucas Jackson/Reuters

A 7-year-old boy from Westchester County is the second child in New York state to die from pediatric multi-symptom inflammatory syndrome tied to COVID-19 since the pandemic began. A 5-year-old boy died earlier in the week from the same syndrome at Mount Sinai Kravis Children’s Hospital in New York City.

The childhood ailment has affected at least 73 children in New York state and authorities are now looking for other potential cases across the country. Cases have also been reported in Washington, D.C., California, Delaware, Louisiana, Massachusetts, Pennsylvania, Washington state and New Jersey, where a 4-year-old died with symptoms last month.

It has been previously thought that children are less likely to suffer any serious complications from the coronavirus.

Read more at The Daily Beast.





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Time is running out for the leap second

Abolition would see 'official' time unmoored from the Sun.




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Second Extinction reveal: Xbox Series X game gives us serious Turok vibes



During Inside Xbox's special stream today, Systemic Reaction gave us our first taste of next-gen dino hunting glory




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White House Misled Public, Buried CDC Reopening Guidelines and is Now Preparing for Second Coronavirus Wave

The White House is making "contingency plans" for a second wave of coronavirus after emails reportedly contradict their claims that Centers for Disease Control and Prevention guidelines to safely reopen the economy were set aside because medical experts did not approve of them.




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We need more video games that are social platforms first, games second

During these long, mundane physically-distant days, stretching on into an uncertain future like an ever-lengthening beigeish corridor, it’s impossible not to miss hanging out with friends. Especially the kind of hanging out where you’re not really doing anything in particular, not talking about any one thing—just kind of being. As we continue to stay physically […]




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Umtiti injured in second session of Barcelona training return

Samuel Umtiti injured his right calf during Barcelona's second training session since being allowed to return to club facilities.






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Second man charged after drugs stolen from pharmacy during alleged armed robbery




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UK pledges £200m to World Health Organisation in battle against second global wave of coronavirus

Read our live coronavirus updates HERE