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Obese Mexican American Children Have Elevated MCP-1, TNF-{alpha}, Monocyte Concentration, and Dyslipidemia

Nearly one-third of all US children are overweight or obese, with even higher prevalence among Mexican American children. Overweight and obesity increase systemic inflammation, contributing to increased risk for chronic diseases, such as type 2 diabetes mellitus and cardiovascular disease.

Obese Mexican American children had concurrent alterations in both inflammatory markers and traditional disease risk markers, relative to healthy weight children. Our results provide evidence partially explaining the health disparity for disease in Mexican American children who are overweight/obese. (Read the full article)




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Health Risks of Oregon Eighth-Grade Participants in the "Choking Game": Results From a Population-Based Survey

Estimates of youth participation in strangulation activity, commonly referred to as the "choking game," range from 5% to 11%. Previous studies have documented correlations between youth choking game participation and health risks such as substance use and mental health issues.

Among Oregon eighth-graders surveyed, >6% had ever participated in the choking game. Participation was linked to poor nutrition and gambling among females, exposure to violence among males, and sexual activity and substance use among both genders. (Read the full article)




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Vitamin B6 Vitamer Concentrations in Cerebrospinal Fluid Differ Between Preterm and Term Newborn Infants

There is no literature on the concentrations of vitamin B6 vitamers in cerebrospinal fluid of preterm and term newborn infants. This knowledge, however, is highly important, because vitamin B6 plays a pivotal role in brain development and functioning.

In cerebrospinal fluid of newborn infants, B6 vitamer concentrations are strongly dependent on postmenstrual age, indicating that vitamin B6 homeostasis in brain differs between preterm and term newborns. This has implications for the evaluation of epilepsy and vitamin B6 deficiency. (Read the full article)




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Prevalence and Correlates of Low Fundamental Movement Skill Competency in Children

Children’s mastery of fundamental movement skills is correlated with a number of health benefits, including higher levels of physical activity, cardiorespiratory fitness, perceived scholastic and athletic competence, and lower levels of overweight.

This is the first study to examine the associations between low skill competence (a new and novel way to report motor skills) and a range of health-related and sociodemographic factors in a large representative sample of children and youth. (Read the full article)




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Culturally Tailored, Family-Centered, Behavioral Obesity Intervention for Latino-American Preschool-aged Children

Childhood obesity is already prevalent by preschool age, particularly among Latinos. Parents have tremendous influence on factors that contribute to childhood obesity (eg, diet, physical activity); thus, family plays a crucial role in pediatric obesity prevention.

This randomized controlled trial examined the effect of a behavioral intervention involving Latino-American parent–preschool-aged child dyads. The intervention resulted in reductions in absolute BMI across the 3-month study period, with patterns suggesting the largest effect for obese children. (Read the full article)




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Bone Mineral Density and Vitamin D Status Among African American Children With Forearm Fractures

Forearm fractures are unique injuries which are associated with lower bone mineral density in adults and white children. The relationships among bone mineral density, 25-hydroxyvitamin D status, and risk for forearm fracture have not been investigated in African American children.

Our data support an association between both lower bone mineral density and vitamin D deficiency and increased odds of forearm fracture in African American children. Promotion of bone health is indicated in this population. (Read the full article)




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Vaccination Coverage Among American Indian and Alaska Native Children, 2006-2010

Disparities in vaccination coverage between American Indian/Alaska Native and white children previously existed between 2001 and 2004 but were not present in 2005.

This study updates a previous study by analyzing data through 2010 and found that these gains have been maintained. (Read the full article)




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Trends in Adverse Reactions to Trimethoprim-Sulfamethoxazole

Antimicrobials are a medication class frequently implicated in pediatric adverse drug reactions (ADRs). Trimethoprim-sulfamethoxazole (TMP-SMX) is long recognized as a contributor to the burden of these undesired and unpredictable events.

TMP-SMX ADRs increased from 2000 to 2009, with the majority of children taking the antibiotic for skin and soft tissue infections. The significant increase in TMP-SMX prescribing for these infections may result in a continued increase of associated ADRs. (Read the full article)




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Changes in Metabolic Syndrome in American and Korean Youth, 1997-2008

In the United States, adolescent obesity rates have tripled in the last 3 decades, with concomitant increases in other metabolic risk factors, including the metabolic syndrome (MetSyn). However, in Asian countries, these same risks have only recently begun increasing.

Representative data for the United States and Korea reveal trends in adolescent obesity and MetSyn moving in opposite directions. This study provides a benchmark for Korea and other Asian countries toward mitigating the upward trends in obesity and MetSyn. (Read the full article)




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Quality of Reporting and Evidence in American Academy of Pediatrics Guidelines

In the only previous cross-sectional study, the quality of pediatric guidelines was rated low on the AGREE-II (Appraisal of Guidelines for Research and Evaluation II) scale. The levels of evidence used in pediatric clinical practice guidelines have never been described.

American Academy of Pediatrics guidelines score low on the AGREE-II scale. Approximately one-quarter of recommendations are based on expert opinion or no reference. These findings support the adoption of standards for guideline development and research targeted toward unsupported recommendations. (Read the full article)




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A Qualitative Study of the Day-to-Day Lives of Obese Mexican-American Adolescent Females

Obesity is a growing concern for Mexican-American adolescents, with both behavioral and cultural variables that are related to the increasing trend.

These results highlight a patient-centered view of the emotional and physical burden of obesity in female Mexican-American adolescents, the families’ personal struggles with weight-related conditions, and the challenge of balancing family needs with those specific to the adolescent. (Read the full article)




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Video Game Use in Boys With Autism Spectrum Disorder, ADHD, or Typical Development

Children with autism spectrum disorder (ASD) and those with ADHD are at risk for problematic video game use. However, group differences in media use or in the factors associated with problematic video game use have not been studied.

Boys with ASD and ADHD demonstrated greater problematic video game use than did boys with typical development. Inattention was uniquely associated with problematic use for both groups, and role-playing game genre was associated with problematic use among the ASD group only. (Read the full article)




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Disparities in Health Insurance Among Children With Same-Sex Parents

Health insurance is associated with improved health for children, but gay and lesbian parents face barriers to adding their children to private health insurance. Little is known about the extent to which insurance disparities exist for children with same-sex parents.

Children with same-sex parents are less likely to have private health insurance. When children live in states in which legal same-sex marriage, civil unions, domestic partnerships, or second-parent adoptions are available, disparities in private insurance diminish for children with same-sex parents. (Read the full article)




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Oral Dexamethasone for Bronchiolitis: A Randomized Trial

Some infants presenting with bronchiolitis are later diagnosed with asthma. Corticosteroid treatment of all infants with bronchiolitis is not clearly efficacious.

We used infant eczema or asthma history in a first-degree relative to select patients with bronchiolitis for dexamethasone or placebo blinded treatment. Dexamethasone treatment of 5 days led to significantly earlier readiness for discharge from infirmary treatment. (Read the full article)




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Impulsivity, "Advergames," and Food Intake

Previous studies have shown that food advertisements influence caloric intake among children. However, individual susceptibility to food advertisements has not been examined thoroughly.

This study examines the role of impulsivity in the effect of food advertisements. An advergame promoting snacks overruled refraining from eating, especially among impulsive children. The findings suggest that impulsivity plays an important role in susceptibility to food advertisements. (Read the full article)




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Identifying Very Preterm Children at Educational Risk Using a School Readiness Framework

Children born very preterm (VPT) are at high risk of educational delay. School readiness has been identified as a potentially useful clinical framework for early detection of those at greatest risk. However, evidence to support its predictive validity is limited.

VPT preschoolers are at risk of impairment across the 5 American Academy of Pediatrics school readiness domains. The number of domains affected predicted likelihood of later learning problems, supporting the utility of schoolreadiness frameworks for identifying children needing surveillance and/or support. (Read the full article)




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Neighborhood Poverty and Allostatic Load in African American Youth

Allostatic load (AL), a biomarker of cardiometabolic risk, predicts the onset of the chronic diseases of aging including cardiac disease, diabetes, hypertension, and stroke. Socioeconomic-related stressors, such as low family income, are associated with AL.

African American youth who grow up in neighborhoods in which poverty levels increase across adolescence evince high AL. The study also highlights the benefits of emotional support in ameliorating this association. (Read the full article)




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Use of Temporary Names for Newborns and Associated Risks

Because there can be no delay in providing newborns with identification wristbands, some hospitals assign newborns temporary first names such as Babyboy or Babygirl. These nondistinct naming conventions result in a large number of patients with similar identifiers in NICUs.

We performed an intervention study to determine if assigning distinct first names at birth would result in a reduction in wrong-patient errors. We used the Retract-and-Reorder tool, an established, automated tool to detect the outcome measure of wrong-patient electronic orders. (Read the full article)




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Dexamethasone Therapy for Septic Arthritis in Children

Two prospective studies of children with septic arthritis have shown that the addition of dexamethasone to antibiotic therapy contributes to clinical and laboratory improvement. Nevertheless, the mainstay of treatment remains antibiotics alone.

This study, which was conducted outside a randomized controlled trial, demonstrates that children with septic arthritis treated early with a short course of adjuvant dexamethasone show earlier improvement in clinical and laboratory parameters than children treated with antibiotics alone. (Read the full article)




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Effects of Genotype and Sleep on Temperament

Sleep disturbances in infants associate with individual differences in temperament. However, little is known about interindividual differences and potential moderating factors, such as genotype.

The results suggest that the cumulative effect of total sleep duration during the first 3 years of life on temperament is moderated by child 5-HTTLPR genotype following a differential susceptibility model. (Read the full article)




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Report: iPhone, iPad, Mac to Run the Same Apps by 2021

Apple is thought to be planning a merger of its app platforms, which means a developer can develop an app once and have it automatically run on iPhone, iPad, and Mac without any extra work. The initiative is called 'Marzipan.'




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The 50 Best iPad Games

Sometimes your iPhone just isn't big enough to enjoy the best of iOS gaming. Grab your iPad and take advantage of the expanded screen real estate with these games.




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Neid named best women's coach in FIFA awards

Silvia Neid, who led Germany to Olympic gold in 2016, was named best coach at The Best FIFA Football Awards as Melanie Behringer just missed out on the top player gong.




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Lucy Bronze named UEFA Women's Player of the Year

Lyon and England right-back Lucy Bronze is the first defender to win the poll of coaches and journalists.




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What Game Are You Playing: Improvement or Innovation?

Improvement and innovation have different rules, expectations, and risks. The key is knowing which game you're playing, but getting the balance right between fostering innovation and fighting for equity may be the challenge of our time.




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Straight Up Conversation: First American to Win WISE Prize for Education Innovation

Rick talks with Larry Rosenstock, education icon, the founder and CEO of High Tech High, and recent recipient of the WISE Prize for Education, about what he's learned after a half century in education.




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Amazon: Just Kidding, You Can Keep Selling Used Nintendo Games

On Thursday, the company sent an email to third-party dealers, saying they would need approval to sell used Nintendo Games. Turns out the email was actually sent out in error, Amazon claims.




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8 Great Gifts for Gamers Under $50

If you're shopping for a gamer, especially if you can pin down their preferred platform, these cheap but fun accessories are guaranteed winners.




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Half-Life Game Series Will Finally Return With VR-Based Project

Valve's tweet describes the upcoming title Half-Life: Alyx as the company's 'flagship VR game.' So you'll probably need a virtual headset to play it. The company will reveal more details on Thursday.




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Retro Console Paradise: A Look at Seoul's Video Game Alley

An underground stall in Seoul's Yongsan district holds one of the biggest classic video game malls you'll ever see. Take a tour through our photos.




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The 10 Best NES Games

The Nintendo Entertainment System (NES) has a huge, diverse library of games. These are the cream of the crop for Nintendo's iconic 8-bit home console




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The 10 Best Nintendo 64 Games

The N64 game library feels historically slim compared to other Nintendo consoles, but these are the greatest Nintendo games of the 64-bit era




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2019's Top 'Free' Games Each Made $1.5 Billion-Plus

Movies are barely earning money compared to the games people don't even have to pay for up front—because in-app purchases are making bank.




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Atari Wants to Build Video Game-Themed Hotels

The first hotel will break ground later this year in Phoenix, Arizona. Another is being planned for Las Vegas. They promise to offer Atari-themed lodging, along with lots of video gaming experiences.




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8 Games You'll Want to Buy in February

February pulls no punches, offering entertainment-starved gamers eight excellent titles to snatch up over the next few weeks.




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Cuthbert's Chelsea strike named best goal: watch the top ten

Erin Cuthbert's strike for Chelsea at Lyon has been named goal of the season: watch the top ten.




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SB 12-02 Agricultural Holdings (Amendment)(Scotland) Bill

9 January 2012This briefing details the development of the Agricultural Holdings (Amendment)(Scotland) Bill and the changes proposed by the Bill.




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SB 14-31 Procurement (Reform) (Scotland) Bill – Parliamentary consideration prior to Stage 3

8 May 2014This briefing summarises Stage 1 and Stage 2 consideration of the Procurement (Reform) (Scotland) Bill, introduced in the Parliament on 3rd October 2013.




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Yes, I Get My Period. School Shouldn't Shame Me for It

Schools should take the lead in removing the stigma around menstruation, writes 16-year-old Maggie Di Sanza, founder of Bleed Shamelessly.




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Boys' and Girls' Brains the Same When It Comes to Math

Boys and girls start out on the same biological footing when it comes to math, according to the first neuroimaging study of math gender differences in children.




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The Marek Wielgus tournament

We travel to Kielce to find out more about one of the leading grassroots events for children in Poland.




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Score a Nikon DSLR Camera, Two Lenses For Less Than $600

This bundle normally sells for $1,149.95 but is available right now for just $596.95, and it will arrive before Christmas with Prime.




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Sony RX100 Buying Guide: Which High-End Compact Camera Is Right for You?

Sony reinvented the premium point-and-shoot camera in 2012 with the RX100. It's continued to build out the series, but has also kept older models on sale. We're here to help you find the right one to suit your needs.




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The Best Point-and-Shoot Cameras for 2020

Unwilling to haul a heavy SLR or mirrorless camera? If you want a capable compact camera you can slip into your pocket, these are the top models we've tested.




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The Best Digital Cameras for 2020

Want better photos than your phone can provide? We test and rate hundreds of cameras and lenses each year, ranging from pocket-friendly shooters to high-end medium format systems. Here's everything you need to know to pick the best digital camera for you.




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In Central Africa, an Urgent Challenge to American Leadership




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Burundi: Breaking the Deadlock, The Urgent Need for a New Negotiating Framework




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Disarmament in the Congo: Investing in Conflict Prevention




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The Inter-Congolese Dialogue: Political Negotiation or Game of Bluff?




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Disarmament in the Congo: Jump-Starting DDRRR to Prevent Further War