Some big games on the horizon as Notre Dame women's basketball is at No. 5 in latest Coaches Poll

AMERICUS, Ga. — Georgia Southwestern State University graduate guard Destiny Garrett was named the Peach Belt Conference Women's Basketball Player of the Week this afternoon by the league office. Garrett set a school record with 13 assists in the 17th-ranked Lady Hurricanes 85-61 win over Florida Tech on Saturday and completed her first-ever double-double with a career-best 21 points. Garrett ...

FSU women's basketball improves to 2-1 after a dominating victory over FAMU on Monday.

Tennessee soccer earned an NCAA Tournament berth for the fourth straight season and will face No. 7 seed Virginia Tech in the first round Friday

On Wednesday at Moody Center, a Lamar team that went 24-7 last season should provide a tougher test for the Longhorns than in their season opener.

EAU CLAIRE— This weekend saw the first basketball games for Blugold men’s and women’s basketball during the Market & Johnson Blugold Tip-Off Tournament. The games were the first to be played at the Sonnentag Event Center, a part of the new $122 million multi-purpose facility which opened earlier this year. The event center has a capacity of 3,500 people for sporting events as compared to the ...

Tallahassee, FL - The South Georgia Technical College Lady Jets dropped a hard fought three-point loss, 50 – 47, to the nationally ranked Eastern Florida State College Titans before rallying to a 66 – 60 victory over Tallahassee State College in the Tallahassee Community College Classic this weekend to move to 3 – 1 on the season. “We put ourselves in a position to beat a very talented team ...

Lauren M. Hablitz
Sep 15, 2021; 41:7698-7711
Review

Systemic study of pathogenic pathways and interrelationships underlying genes associated with Alzheimer's disease (AD) facilitates the identification of new targets for effective treatments. Recently available large-scale multiomics datasets provide opportunities to use computational approaches for such studies. Here, we devised a novel disease gene identification (digID) computational framework that consists of a semi-supervised deep learning classifier to predict AD-associated genes and a protein–protein interaction (PPI) network-based analysis to prioritize the importance of these predicted genes in AD. digID predicted 1,529 AD-associated genes and revealed potentially new AD molecular mechanisms and therapeutic targets including GNAI1 and GNB1, two G-protein subunits that regulate cell signaling, and KNG1, an upstream modulator of CDC42 small G-protein signaling and mediator of inflammation and candidate coregulator of amyloid precursor protein (APP). Analysis of mRNA expression validated their dysregulation in AD brains but further revealed the significant spatial patterns in different brain regions as well as among different subregions of the frontal cortex and hippocampi. Super-resolution STochastic Optical Reconstruction Microscopy (STORM) further demonstrated their subcellular colocalization and molecular interactions with APP in a transgenic mouse model of both sexes with AD-like mutations. These studies support the predictions made by digID while highlighting the importance of concurrent biological validation of computationally identified gene clusters as potential new AD therapeutic targets.

A new book from the Smithsonian’s National Museum of African American History and Culture shows the images and impacts of athletes on and off the playing field

Representatives of all countries in Latin America and the Caribbean have gathered here this week to agree on the actions needed to definitively eradicate hunger in the region before 2025. [...]

With rapid soil degradation, fast depletion of groundwater, excessive use of pesticides-fertilizers and extreme weather events all collectively putting stress on farming and forestry, it is time to recognise the [...]

FAO Director-General José Graziano da Silva has been selected as one of the world's most influential Latin Americans for his work against hunger and malnutrition in the world. In its [...]

Addressing the plenary meeting in the closing session of the 159^th Session of the Council, the Director-General expressed his appreciation to delegates for their commitment and hard work to [...]

The Food and Agriculture Organization of the United Nations (FAO), in collaboration with the Secretariat of the Convention on Biological Diversity (CBD), will hold a Global Dialogue on the [...]

Under exuberant coach, Knute Rockne, Notre Dame set the standards for football excellence. But off the field, the Fighting Irish was a PR sensation, capturing the hearts of a riveted nation.

Coffee - it's a staple of American life, and inside the vaults of the National Museum of American History, they know the secret to its wide spread success: packaging

How did a god fearing church-goer like Lizzie Borden become a suspect in the gruesome crime of the century? Her inconsistent account, and an eerie nonchalance, immediately damaged her credibility with investigators.

In March 1895, Boston and New York City began an epic and highly competitive race to become the first American city with a working subway system.

By late September 1918, in a bid to contain the spread of the flu, the U.S. had made the decision to cancel the draft. It was too little, too late—in October alone, over 200,000 Americans were killed by the disease.

After his arrival in Omaha in 1892, Tom Dennison - nicknamed the "Grey Wolf" - controlled the city's street's for more than 30 years

Transitions: Photographs by Robert Creamer

Hours after the Titanic sank, news organizations latched onto a telegraph message that seemed to say that the ship and all its passengers had been rescued. It would turn out to be a tragic case of fake news.

In 1619, George Yeardley, the newly appointed governor of Jamestown, made history: He convened 22 elected members of a burgeoning commonwealth, creating the first democratic assembly in America.

A step-by-step tour of the renovation of the National Museum of American History (Narration by Beth Py-Lieberman / Edited by Ryan Reed and Brian Wolly)

Aziz Ansari | Smithsonian Magazine’s 2016 American Ingenuity Award Winner for Performing Arts The actor, comedian and author is being honored for his starring role as Dev Shah in “Master of None,” the Netflix series that he created with Alan Yang. Like the character he plays, Ansari is the son of Indian immigrant parents, and his smart, surprising take on life, love, technology and cultural identity in the United States has helped make the show “the year’s best comedy straight out of the gate,” as the New York Times put it. Among Ansari’s other accomplishments are his unforgettable portrayal of the loopy Tom Haverford on NBC’s “Parks and Recreation,” his best-selling book about dating in the internet age, Modern Romance (co-authored with Eric Klinenberg), and his blockbuster stand-up act that sold out Madison Square Garden. Read more about Ansari’s work: http://smithmag.co/jvdAaL | #IngenuityAwards And more about the American Ingenuity Awards: http://smithmag.co/77xPqy

A close look reveals how the famed photographer altered his glass negatives, creating the popular image of Native Americans that still exists today

In 1918, Lulu Hunt Peters—one of the first women in America to earn a medical doctorate—published the best seller Diet and Health With Key to the Calories, making a name for herself as an apostle for weight reduction in an era when malnutrition was a far greater public health threat than obesity. She pioneered the idea of measuring food intake via the calorie, which at the time was an obscure unit of measurement familiar only to chemists.  A century later, the Centers for Disease Control and Prevention reports (https://www.cdc.gov/nchs/products/databriefs/db360.htm) that 42 percent of American adults are clinically obese and that Type 2 diabetes is on the rise (https://www.cdc.gov/media/releases/2022/p1229-future-diabetes-surge.html) . With those who can afford it now turning to pharmaceuticals to help them lose weight, we’ll examine why and how calorie counting has failed to help Americans maintain a “healthy” weight.  In this episode of “There’s More to That,” we hear from food historian Michelle Stacey about Peters’ legacy—and from Ronald Young Jr., creator and host of the critically acclaimed podcast “Weight For It (https://www.radiotopia.fm/podcasts/weight-for-it) ,” about how American society continues to stigmatize what he calls “fat folks” for reasons that have nothing to do with public, or even individual, health. A transcript is below. To subscribe to “There’s More to That,” and to listen to past episodes on the complex legacy of Sojourner Truth (https://www.smithsonianmag.com/history/how-to-separate-fact-from-myth-in-the-extraordinary-story-of-sojourner-truth-180983820/) , how Joan Baez opened the door for Taylor Swift (https://www.smithsonianmag.com/arts-culture/before-beyonce-taylor-swift-ran-world-joan-baez-180983893/) , how machine learning is helping archeologists to read scrolls (https://www.smithsonianmag.com/history/how-artificial-intelligence-is-making-2000-year-old-scrolls-readable-again-180984264/) buried by the eruption of Mount Vesuvius nearly 2,000 years ago and more, find us on Apple Podcasts (https://podcasts.apple.com/us/podcast/theres-more-to-that/id1694965155?ign-itscg=30200&ign-itsct=podcast_box_player) , Spotify (https://open.spotify.com/show/4NYRCRxkYJTLjW71sqYOFv?si=08fa62c3e59d450f&nd=1) or wherever you get your podcasts. Read Michelle Stacey's story about Dr. Lulu Hunt Peters in the June 2024 issue of Smithsonian here (https://www.smithsonianmag.com/science-nature/doctor-pioneered-counting-calories-century-ago-were-still-dealing-with-consequences-180984282/) . Listen to Ronald Young, Jr.'s podcast "Weight For It" here (https://www.radiotopia.fm/podcasts/weight-for-it) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Rye Dorsey, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz. Music by APM Music.

The North American Orchid Conservation Center is working to ensure the survival of some of the most unique plants in the world

The grand buildings of Washington, D.C. would look quite different were it not for the work of Palladio. Read more at Smithsonian.com

In the 1920s, the U.S. was in full thrill-seeking mode. From horse-diving (you have to see it to believe it) to barnstorming. And at the center of many of these activities were a group of daring young women.

"OK Go made music videos relevant again." – Stephen Colbert OK Go​, Damian Kulash Jr. and Trish Sie​ won the Smithsonian magazine​ American Ingenuity Award for Visual Arts for pushing the music-video envelope with their zero-gravity video for "Upside Down & Inside Out." Read more about their work and see the video here: http://smithmag.co/HZ8vzr The Smithsonian has been celebrating innovation in American culture for more than 150 years, and following in this tradition, Smithsonian magazine presents the American Ingenuity Awards, honoring revolutionary breakthroughs in the arts and sciences, education and social progress. http://smithmag.co/R7hyRO

Fannie Lou Hamer, a voting rights activist, suffered unspeakable violence and intimidation at the hands of white supremacists and police. Her response: to elevate her cause by launching a long-shot campaign for the U.S. Senate

African cuisine has always been well represented in the United States, particularly in dishes characterized as “Southern” in origin, like gumbo or hoppin’ john. But even before chef Serigne Mbaye’s New Orleans eatery Dakar NOLA was named (https://www.eater.com/24175309/james-beard-awards-2024-winners-restaurant-and-chef-awards) the Best New Restaurant of 2024 at the James Beard Awards this week, the contributions of the African diaspora to the American diet had at last begun to enjoy a long-overdue reappraisal via reality television, Netflix docuseries and, most important, a number of widely praised dining establishments: If you want to book a table at Tatiana (https://www.tatiananyc.com/story/) in Manhattan, Dept of Culture (https://www.deptofculturebk.com/) in Brooklyn or Kann (https://kannrestaurant.com/) in Portland, you’d better plan ahead, because their tables are often booked up well in advance. In this episode, Smithsonian contributor Rosalind Cummings-Yeates explains how the ascendancy of pan-African cuisine from “auntie” restaurants into the rarefied fine dining sphere is part of a larger and more meaningful campaign of cultural reclamation. And Mbaye tells us why it was so important to him to make Dakar NOLA (https://www.dakarnola.com/) a showcase of the distinctive flavors of Senegal, where he spent his formative years. Read Rosalind's Smithsonian story about the rise of West African fine dining in the U.S. here (https://www.smithsonianmag.com/arts-culture/these-chefs-are-elevating-african-and-caribbean-cuisines-from-carryouts-to-fine-dining-180984466/) . See the full list of 2024's James Beard Award winners here (https://www.jamesbeard.org/blog/the-2024-james-beard-award-winners) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Rye Dorsey, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz / photography by Katherine Kimball, Joshua Brasted, and Jeremy Tauriac Music by APM Music.

Book-banning might seem like a relic of less enlightened times, but the practice is back in a big way. The American Library Association reports (https://www.smithsonianmag.com/smart-news/american-library-association-names-2022s-most-banned-books-180982048/) that 2022 saw more attempts to have books removed from public libraries than in any prior year this century — indeed, it documented more than twice as many attempted bans in 2022 than in 2021. In schools, attempts to keep certain books out of the hands of students have been even more aggressive and draconian. What’s new about these efforts is the subject that binds the most-challenged titles: Most of them address themes of LGBT+ identity or gender expression. In this episode, we talk with journalist Colleen Connolly about Thomas Morton’s New English Canaan, the first book ever to be suppressed in North America. What did the Puritans find so threatening about it, and how has this book echoed through subsequent centuries? Then we’re joined by Dr. Carla Hayden, Librarian of Congress, for a wide-ranging conversation about the history of book bans in the United States, how a resurgent wave of book bans in many states differs from those of prior eras, and why organized attempts to prevent specific people from reading specific books usually fail. A transcript of this episode can be found here (http://smithsonianmag.com/history/a-brief-history-of-banned-books-in-america-180983011) . Read Colleen’s Smithsonian story about New English Canaan here (https://www.smithsonianmag.com/history/how-americas-first-banned-book-survived-and-became-an-anti-authoritarian-icon-180982971/) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Fact-checking by Stephanie Abramson. Episode artwork by Emily Lankiewicz. Music by APM Music.

Read more at http://www.smithsonianmag.com/history-archaeology/Nikita-in-Hollywood.html As part of a diplomatic mission, Soviet premier Nikita Khrushchev traveled across the United States, meeting Americans from New York to Iowa to California.

Ancient Greeks were endlessly fascinated by Egyptian culture, and especially the Egyptian Gods whom they saw as versions of their own. So much so that they ended up adopting Egyptian culture and customs as their own.

The National Gallery of Art organized a comprehensive exhibit of Robert Frank's work (Images courtesy of: National Gallery of Art; Produced by: Diane Bolz and Brian Wolly)

Read more at http://blogs.smithsonianmag.com/aroundthemall/2008/12/music-of-the-tropics-balinese-drum-troupe-performs-at-the-sackler/ Bells and gongs are the sounds behind Gamelan music, which has different variants from one Indonesian island to the next.

Take a tour of the National Mall, past and present (Kenneth R. Fletcher). Read more at https://www.smithsonianmag.com/arts-culture/a-brief-history-of-pierre-lenfant-and-washington-dc-39487784/

Watch newsreel footage of Angel Macias' astonishing performance at the Little League World Series.

Boston’s iconic lighthouse, the Boston Light, is managed by a single person: Sally Snowman. She is the 70th keeper of the lighthouse since it was built over 300 years ago.

The 6888th Central Postal Directory Battalion was the only unit comprised entirely of Black women to have been deployed overseas during World War II, and it had served a critical function: clearing the backlog of mail that marked the only line of communication between American soldiers in Europe and their loved ones back home. In this episode, we speak with retired Army Colonel Edna Cummings, who made it her business to get the 6888 their belated recognition, and with Smithsonian magazine senior writer Jennie Rothenberg Gritz, who wrote about Col. Cummings' quest (https://www.smithsonianmag.com/history/how-all-black-female-WWII-unit-saved-morale-battlefield-180981540/) for the March 2023 issue of Smithsonian. NOTE: In the interval since we recorded our interview with Col. Cummings, another veteran from the 6888 has died. With the passing of Crescencia J. Garcia last month at the age of 103, there are now five women who served in the 6888 during World War II who remain alive. Learn more about the women of the 6888th Central Postal Battalion at the Women of the 6888th site (https://www.womenofthe6888th.org/) . Find prior episodes of our show here (https://www.smithsonianmag.com/podcast/) . There’s More to That is a production of Smithsonian magazine and PRX Productions. From the magazine, our team is Chris Klimek, Debra Rosenberg and Brian Wolly. From PRX, our team is Jessica Miller, Adriana Rosas Rivera, Genevieve Sponsler, Terence Bernardo, and Edwin Ochoa. The Executive Producer of PRX Productions is Jocelyn Gonzales. Episode artwork by Emily Lankiewicz. Music by APM Music.

The Chicago White Sox were heavy favorites going into the 1919 World Series. But they were defeated by the Cincinnati Reds - and it soon became clear that the game was rigged

The musicians of the Union and Confederate armies provided strong memories of the homes left behind for the battlefield.

Chris Melissinos, guest curator of an exhibit about video games at the Smithsonian American Art Museum, explains what makes the genre an art form

Merry "Corky" White, author of Coffee Life in Japan, traces the history of coffee culture in the United States

During World War II, Japanese Americans who were sent to internment camps used scraps and found materials to create beautiful works of art.

Lonnie Bunch, the director of the National Museum of African American History and Culture, discusses the Martin Luther King, Jr. memorial, one of America's greatest monuments.