[Updated] Minister of Home Affairs Walter Roban held a press conference this afternoon [July 7] to introduce the new Solar Photovoltaic Certification Training Programme. The press conference has just concluded and we will have additional information later on, and in the meantime the live video replay is below. Update 3.05pm: Minister Roban’s remarks: Good afternoon […]

The Bermuda Golf Association launched its Junior Golf Program for Fall 2024, powered by Operation 36. A spokesperson said, “The program will begin the week of September 30th and run through the week of November 18th, with breaks for the October half-term, November 11th holiday, and PGA Tour event. “Group lessons will take place at Ocean […]

The Bermuda Golf Association, alongside The Bermuda Golf Foundation, has launched the Operation 36 program at Ocean View Golf Course. A spokesperson said, “The Bermuda Golf Association [BGA], the National Sport Governing Body for golf and The Bermuda Golf Foundation [Charity #141] are delighted to announce the launch of the Operation 36 program at Ocean […]

The Dance Programme at the Berkeley Institute is set to perform “#Trending,” a student-choreographed dance showcase inspired by the influence of social media on daily life, on Wednesday, March 27th. A spokesperson said, “Social Media is an integral aspect of our daily lives, even more so with our youth. This is the inspiration behind ‘#Trending’ […]

Port Royal Golf Course, which recently celebrated its 50th anniversary, made time to allow their staff to receive training organized by the Bermuda Tourism Authority. A spokesperson said, “AnchorBDA is City & Guilds certified and was created by the Bermuda Tourism Authority [BTA] to establish our own industry-recognised designation to empower residents. This designation is […]

1. New program will see pregnant mothers and babies protected from life-threatening virus  SBS
2. World-leading approach to protect babies from RSV  Department of Health
3. Government-funded RSV vaccines to protect infants from severe disease  Australian Pharmacist
4. 'Very scary': Wagga mum's plea for parents to protect babies through RSV jab  The Daily Advertiser
5. Guild backs free RSV vaccinations  Australian Journal of Pharmacy

A comment on my previous post said,

The most difficult thing when coming to a different language is to leave the other language behind. The kind of friction experienced here is common when transliterating ideas from one language to another. Go (in this case) is telling you it just doesn't like to work like this.

Try writing simple Go, instead of reaching for Lisp idioms. Then find the ways that work for Go to express the concepts you find.

That's not at all how I approach programming.

A friend of mine once paid me a high compliment. He said, “Even your C code looks like Lisp.”

When I write code, I don't think in terms of the language I'm using, I think in terms of the problem I'm solving. I'm a mostly functional programmer, so I like to think in terms of functions and abstractions. I mostly reason about my code informally, but I draw upon the formal framework of Lambda Calculus. Lambda Calculus is a simple, but powerful (and universal) model of computation.

Programming therefore becomes a matter of expressing the solution to a problem with the syntax and idioms of the language I'm using. Lisp was inspired by Lambda Calculus, so there is little friction in expressing computations in Lisp. Lisp is extensible and customizable, so I can add new syntax and idioms as desired.

Other languages are less accommodating. Some computations are not easily expressable in the syntax of the language, or the semantics of the language are quirky and inconsistent. Essentially, every general purpose fourth generation programming language can be viewed as a poorly-specified, half-assed, incomplete, bug-ridden implementation of half of Common Lisp. The friction comes from working around the limitations of the language.

Why the government's flood insurance program is underwater Major flooding events are increasingly common across the U.S., but homeowners looking for flood insurance will find few choices. The main providers of flood insurance is the U.S. government through the National Flood Insurance Program, or…

This evaluation report is based on feedback from people living with dementia and carers who received an Individual Award from the Life Changes Trust. The Individual Awards Pilot Scheme was run in Argyll & Bute and Edinburgh in 2014-15 and aimed to provide a small amount of additional financial empowerment to a number of individuals whose lives have been affected by dementia, to help improve their well-being and quality of life. A secondary aim of the pilot scheme was to find out what people would spend the Award on when given relatively broad choice, and what benefit that might bring in the short and medium terms.

When Windows tells you it's out of memory, what does it mean and what can you do about it?

How Do I Tell Which Program Is Using So Much Memory? from Ask Leo!.
Get the Confident Computing weekly newsletter: https://newsletter.askleo.com

The expansion will allow other national laboratories to join PPPL in supporting the growth of the next generation of innovators and technicians.

“Close Encounters: Facing the Bomb in a New Nuclear Age” is on display at SPIA’s Bernstein Gallery through Oct. 25. 

Come do Competitive Programming at Princeton! Improve your coding abilities. Increase your knowledge of algorithms and data structures. Learn problem solving skills.

Come do Competitive Programming at Princeton! Improve your coding abilities. Increase your knowledge of algorithms and data structures. Learn problem solving skills.

The Program in Visual Arts hosts an info session for all sophomores interested in the program minor and the Art & Archaeology Practice of Art track major. Students will have the opportunity to meet current faculty, majors, and minors to ask questions about the program and application process.

Come do Competitive Programming at Princeton! Improve your coding abilities. Increase your knowledge of algorithms and data structures. Learn problem solving skills.

Join us in an engaging workshop to learn how to think like a start-up and see if your research or innovation has the potential to effectively solve real-world problems. Our Novus I-Corps Program at Princeton University is a half-day introduction to I-Corps hosted by the NSF I-Corps Northeast Hub(Link opens in new window). The Novus I-Corps Program at Princeton University provides an opportunity for individuals and teams with innovations or ideas to: Shift the mindset from science and technology to the people who would benefit Understand how Customer Discovery drives innovation (and gets you out of the building!). Meet local leaders in NSF I-Corps and Princeton University's Office of Innovation to guide your journey. Learn tips for success from an I-Corps Alumni Panel sharing their experience. Network with innovation-minded individuals to help form teams or guide your next steps. Who Should Attend: (Individuals and teams from any campus are invited) Princeton University faculty, postdoctoral researchers, graduate students, undergraduates, and alumni who are developing a scientific discovery or technical innovation. Local academic researchers from nearby institutions are welcome to attend. Individuals, including community innovators & local entrepreneurs, who want to learn how innovation happens at the Rutgers University and potentially join a team. Student Organization / Program Leaders who want to learn more about how I-Corps can benefit their members. Potential Mentors looking to get involved in supporting Rutgers startups. Benefits: TRAINING: Three-hour training introducing the I-Corps Lean LaunchPad approach to evaluating technologies through customer-discovery research, focused on identifying the technology’s potential for development in a startup or other venture. NETWORKING: Build relationships with local I-Corps program leaders to get guidance and support. Individuals can form teams to be eligible to apply for the Regional I-Corps program. PREPARATION: Attendees will be prepared to begin a journey of Customer Discovery with their own team or with a team they newly created. FOLLOW-ON OPPORTUNITIES: Attendees can be fast-tracked to an upcoming 4-week regional I-Corps Program and have access to a $1,500 NSF grant to do Customer Discovery. Teams who complete 20+ interviews after Novus can become eligible to apply for the $50k National I-Corps Teams program.

Students across the country are participating in NOVA's film production program to make videos about climate change solutions in their local communities.

Engage your students with science journalism about issues in their communities with the NOVA Science Studio program!

Join our reseller partner program and grow your digital signage business. Purchase software licences as and when you need them and we give you all the presales and technical support you need. Simple to use digital signage computer software allows content to be displayed on screens anywhere in the world.

This marks the launch of various ventures, including a festival project, a therapeutic space with therapy animals, and a holistic health program for women. 

Oman, otherwise officially known as the Sultanate of Oman, is within the southeastern portion of the Arabian Peninsula. The country is surrounded by two sea bodies including the Arabian Sea in the southeast and the Sea of Oman in the northeastern portion. A larger body of water, the Indian Ocean, is also near Oman in the southeastern area like the Arabian Sea. Americans, Canadians, and other digital nomads from various countries can easily assimilate as digital nomads since English is a widely used language besides the official language, Arabic. While there is no digital nomad visa program in Oman, you can opt to apply for an employment visa. If you are a digital nomad, you will have to apply for various eVisas depending on where you are going, such as an eVisa Ethiopia. How To Apply for An Employment Visa in Oman Applying for an employment visa in Oman takes six steps with an overall turnaround time of up to 9 weeks long depending on individual processing time. The first step is the initiation process where you have to contact Fakhoury Global Immigration and send in the appropriate documents to start applying for the employment visa. This initial step only takes about 24-72 hours. The second step involves filling out the labor permit application and waiting for that to be approved within 3 to 4 weeks. For step 3, you must fill out the employment visa application and provide the mandated documents. Take everything to the closest Royal Oman Police location for full processing within 1 week to a month. The fourth step involves entering Oman where you can begin your digital nomad endeavors once this happens. For step 5, you need to have a health exam at one of the entity’s supported clinics. You will need a chest X-ray, blood tests to be sure you don’t have any bad diseases, as well as pee and poop samples for a full health profile. The final step is applying for and receiving a residential ID card from the Directorates General of Civil Status. The Benefits of Being A Digital Nomad In Oman Your day can be filled with exploring what Oman has to offer in between getting your work done on your laptop. You can have breakfast at Tr.Eat Cafe and get your work done with nearby free Wi-Fi. Then, you can take a break and explore the Sultan Qaboos Grand Mosque in the afternoon before grabbing dinner at Theatrum Restaurant. Plan your itinerary in Oman around your work schedule so that you can still have fun where you are temporarily living while getting your work done. Locating yourself in Muscat would be your best bet as it is the most popular part of Oman with the most free Wi-Fi spots so you can have a variety of places to work. Work can get boring if you are working in the same place every day. Instead of purchasing expensive home Internet, you can plan your day to be located near free Wi-Fi spots to get your work done. No Internet access at home can help you to stay connected to yourself with non-tech activities like reading a book or embarking on a hobby before you go back to being a digital nomad exploring Oman the next day. Where Can I Get Free Wi-Fi in Oman? According to WiFi Map, the top 5 places with free Wi-Fi in Oman are Muscat, Seeb, Salalah, Sohar, and Matrah. Muscat is the most popular region of Oman with free Wi-Fi spots, featuring 2,883 locations to connect with your laptop to complete your workload. When you first enter Muscat or another popular region in Oman with Wi-Fi spots, you can download WiFi Map to your smartphone so you are informed of all the nearby spots where you can get connected. Local hotels, cafes, restaurants, and other businesses could have free Wi-Fi for their patrons. Maybe you want to explore a part of Oman that you have not seen yet. Book a few days at a local hotel and you can utilize the free Wi-Fi there. Whenever you stop at a cafe or restaurant for a meal, you can get some work done after eating before you go to your next destination. Become A Digital Nomad in Oman Today! Oman has so much to offer such as opera houses, mosques, delightful eateries, and forts like the Jibreen Castle. Wadi Bani Khalid is a desert retreat with a mountainous landscape and clear green waters for swimming. When you have to stay connected to work, you can stop by one of the most popular Wi-Fi spots in Muscat. When you want to explore Oman’s attractions and eateries, you can put away your work and enjoy life. Being a digital nomad in Oman can change your life so start the employment visa process today! Author Bio: Cathy Slater is an experienced content writer. She is associated with many renowned travel blogs as a guest author where she shares her valuable travel tips with the audience.

The post Does Oman Have A Specific Digital Nomad Visa Program? appeared first on Geeky Traveller.

The genetic testing company 23andMe announced it will cut 40% of its workforce, or 200 jobs, and halt the work on therapies it was developing. As the BBC notes, the company is fighting for survival after hackers gained access to personal information of millions of its users, causing the stock to crater by more than 70%. All seven of its independent directors also resigned in September, following a protracted negotiation with founder and Chief Executive Anne Wojcicki over her plan to take the company private. The BBC reports: On Tuesday, the company warned investors of "substantial doubt" about its ability to continue operating, as it reported that revenue had fallen to $44 million between July and September compared to $50 million in the same period last year. Losses fell to $59 million from $75 million. The job cuts are expected to lead to one-off costs of $12 million, including severance pay, for the plan that will result in savings of $35 million. "We are taking these difficult but necessary actions as we restructure 23andMe and focus on the long-term success of our core consumer business and research partnerships," Ms Wojcicki said. The company also said it is considering what to do with the therapies it had in development, including licensing or selling them. 23andMe is a giant of the growing ancestor-tracing industry. It offers genetic testing from DNA, with ancestry breakdown and personalised health insights. Its customers include famous names, from rapper Snoop Dogg to multi-billionaire investor Warren Buffett. The company was valued at roughly $3.5 billion when it listed on the Nasdaq stock exchange in 2021 and its share price peaked at $17.65. But they have since tumbled and are currently trading at less than $5.

Read more of this story at Slashdot.

velocityconf: New #velocityconf CA program preview is up: http://t.co/rKjf91RXdD @ariyahidayat on End-to-End JS Quality Analysis.

Creon Butler appointed to lead Global Economy and Finance Programme News Release sysadmin 22 October 2019

Creon Butler has been appointed to lead the Global Economy and Finance programme at Chatham House, joining the institute at the beginning of December. He will also form part of the institute’s senior leadership team.

The Math Community Educational Outreach (Math CEO) program at the University of California, Irvine (UCI) will receive the 2025 AMS Award for an Exemplary Program or Achievement in a Mathematics Department.

Founded in 2014, UCI’s Math CEO is an after-school math enrichment program aimed at increasing the number of talented students in STEM from diverse backgrounds by fostering mathematical exploration, mentor development, and community engagement.

From the citation

The University of California, Irvine (UCI) Math CEO program is recognized for its exceptional contributions to the mathematics community and society at large. Established in 2014 by professors Alessandra Pantano and Li-Sheng Tseng, Math CEO targets students from Title I middle schools, providing them with a high-quality after-school math enrichment program. This program brings middle-school students to the UCI campus to work in small groups with undergraduate mentors, many of whom are also from historically marginalized groups, to engage in challenging mathematical tasks and encourage exploration. 

From September 2019 to June 2024, Math CEO engaged a total of 1,221 youth, with 48.6% identifying as female. The ethnic background of the participants was predominantly Latinx (93.5%), with smaller representations of Asian, white, and multiethnic students. In the same five-year period, Math CEO engaged 553 undergraduate mentors, 62.2% of whom were female. The mentors’ ethnic backgrounds were diverse, with significant representation of Asian (52%) and Latinx (30%) students. The undergraduate mentors, many of whom pursue careers in education, receive training in culturally responsive teaching practices and equity in education, significantly impacting their professional development. In a post-survey, 52.3% of the undergraduate mentors expressed interest in teaching or working in education and 45.9% were likely to pursue professions working with children or families.

Recognizing the central role of families in supporting Latinx youth, Math CEO involves parents through bilingual workshops that enhance community awareness of college pathways and financial opportunities. 

Math CEO has been the foundation for numerous research projects in mathematics education, supported by NSF grants, leading to publications and program growth. The program’s success is evident in its expansion to high schools and other regions in Southern California, including a new branch at California State University, Dominguez Hills. Math CEO continues to make a substantial impact on underserved youth, demonstrating a model of systemic, reproducible change that can be implemented by others.

Response of Alessandra Pantano, UCI Math CEO

I am deeply honored to receive the AMS Award for an Exemplary Program in a Mathematics Department on behalf of the UCI Math CEO team. This wonderful award recognizes the work of many colleagues, graduate students, and undergraduate students in developing and delivering the UCI Math Community Educational Outreach (Math CEO) program. For over a decade, Math CEO has provided creative and culturally responsive math enrichment opportunities for hundreds of underprivileged middle-school students, many of which have since “graduated” to high school or even college. Leading this exceptional and dedicated team of volunteers has been the highest pride of my professional life. A special thanks to my partners-in-crime, Prof. Li-Sheng Tseng, codirector of Math CEO, and former graduate student Andres Forero Cuervo, academic coordinator for Math CEO: We could have never done this without you. I look forward to pushing this activity forward and continuing to dedicate my energy to help kids in our county find the way to express their potential – in math and in life! A big thanks to the colleagues who nominated us and to the AMS for recognizing our efforts.  

History of the program

The UC Irvine Math Community Educational Outreach (Math CEO) program was founded in 2014 by math faculty Alessandra Pantano and Li-Sheng Tseng in collaboration with Santa Ana Unified math teacher Jasmina Matasovic. The founders shared a belief that low standardized test scores in underserved communities do not reflect students’ interest and potential to succeed in STEM. Math CEO runs free, weekly, after-school math enrichment sessions, welcoming all youth regardless of math achievement. Starting with only 25 students from one middle school, the program has grown and engaged nearly two thousand students in all, from multiple school districts in Southern California.

About the award

The annual AMS Award for an Exemplary Program or Achievement in a Mathematics Department was established in 2004 and first given in 2006. This award recognizes a department which has distinguished itself by undertaking an unusual or particularly effective program of value to the mathematics community, internally or in relation to the rest of society. Departments of mathematical sciences in North America that offer at least a bachelor’s degree in mathematical sciences are eligible. The award amount is currently $5,000. The award will be presented at the 2025 Joint Mathematics Meetings in Seattle.

Learn more about the award and previous recipients.

Contact: AMS Communications.

*****

The American Mathematical Society is dedicated to advancing research and connecting the diverse global mathematical community through our publications, meetings and conferences, MathSciNet, professional services, advocacy, and awareness programs.
 

Programmed ribosomal frameshifting (PRF) is a mechanism used by arteriviruses like porcine reproductive and respiratory syndrome virus (PRRSV) to generate multiple proteins from overlapping reading frames within its RNA genome. PRRSV employs −1 PRF directed by RNA secondary and tertiary structures within its viral genome (canonical PRF), as well as a noncanonical −1 and −2 PRF that are stimulated by the interactions of PRRSV nonstructural protein 1β (nsp1β) and host protein poly(C)-binding protein (PCBP) 1 or 2 with the viral genome. Together, nsp1β and one of the PCBPs act as transactivators that bind a C-rich motif near the shift site to stimulate −1 and −2 PRF, thereby enabling the ribosome to generate two frameshift products that are implicated in viral immune evasion. How nsp1β and PCBP associate with the viral RNA genome remains unclear. Here, we describe the purification of the nsp1β:PCBP2:viral RNA complex on a scale sufficient for structural analysis using small-angle X-ray scattering and stochiometric analysis by analytical ultracentrifugation. The proteins associate with the RNA C-rich motif as a 1:1:1 complex. The monomeric form of nsp1β within the complex differs from previously reported homodimer identified by X-ray crystallography. Functional analysis of the complex via mutational analysis combined with RNA-binding assays and cell-based frameshifting reporter assays reveal a number of key residues within nsp1β and PCBP2 that are involved in complex formation and function. Our results suggest that nsp1β and PCBP2 both interact directly with viral RNA during formation of the complex to coordinate this unusual PRF mechanism.

Methionine, through S-adenosylmethionine, activates a multifaceted growth program in which ribosome biogenesis, carbon metabolism, and amino acid and nucleotide biosynthesis are induced. This growth program requires the activity of the Gcn4 transcription factor (called ATF4 in mammals), which facilitates the supply of metabolic precursors that are essential for anabolism. However, how Gcn4 itself is regulated in the presence of methionine is unknown. Here, we discover that Gcn4 protein levels are increased by methionine, despite conditions of high cell growth and translation (in which the roles of Gcn4 are not well-studied). We demonstrate that this mechanism of Gcn4 induction is independent of transcription, as well as the conventional Gcn2/eIF2α-mediated increased translation of Gcn4. Instead, when methionine is abundant, Gcn4 phosphorylation is decreased, which reduces its ubiquitination and therefore degradation. Gcn4 is dephosphorylated by the protein phosphatase 2A (PP2A); our data show that when methionine is abundant, the conserved methyltransferase Ppm1 methylates and alters the activity of the catalytic subunit of PP2A, shifting the balance of Gcn4 toward a dephosphorylated, stable state. The absence of Ppm1 or the loss of the PP2A methylation destabilizes Gcn4 even when methionine is abundant, leading to collapse of the Gcn4-dependent anabolic program. These findings reveal a novel, methionine-dependent signaling and regulatory axis. Here methionine directs the conserved methyltransferase Ppm1 via its target phosphatase PP2A to selectively stabilize Gcn4. Through this, cells conditionally modify a major phosphatase to stabilize a metabolic master regulator and drive anabolism.

Pour de nombreuses personnes, perte de poids rime obligatoirement avec privations. Et si vous appreniez aujourd’hui que vous pouvez perdre efficacement vos kilos en trop sans pour autant vous priver excessivement ? De nombreux programmes minceur et de rééquilibrage, notamment Croq’kilos offrent ce genre d’alternative. Mais de quoi s’agit-il réellement ? C’est quoi Croq’Kilos ? Croq’Kilos […]

L’article Croq’Kilos : programme minceur, rééquilibrage alimentaire est apparu en premier sur Ortho Doc France.

Ankylosing Spondylitis (AS) is a common, inflammatory rheumatic disease, which primarily affects the axial skeleton and is associated with sacroiliitis, uveitis and enthesitis. Unlike other autoimmune rheumatic diseases, such as rheumatoid arthritis or systemic lupus erythematosus, autoantibodies have not yet been reported to be a feature of AS. We therefore wished to determine if plasma from patients with AS contained autoantibodies and if so, characterize and quantify this response in comparison to patients with Rheumatoid Arthritis (RA) and healthy controls. Two high-density nucleic acid programmable protein arrays expressing a total of 3498 proteins were screened with plasma from 25 patients with AS, 17 with RA and 25 healthy controls. Autoantigens identified were subjected to Ingenuity Pathway Analysis in order to determine patterns of signalling cascades or tissue origin. 44% of patients with Ankylosing Spondylitis demonstrated a broad autoantibody response, as compared to 33% of patients with RA and only 8% of healthy controls. Individuals with AS demonstrated autoantibody responses to shared autoantigens, and 60% of autoantigens identified in the AS cohort were restricted to that group. The AS patients autoantibody responses were targeted towards connective, skeletal and muscular tissue, unlike those of RA patients or healthy controls. Thus, patients with AS show evidence of systemic humoral autoimmunity and multispecific autoantibody production. Nucleic Acid Programmable Protein Arrays constitute a powerful tool to study autoimmune diseases.

Genetic-testing lab 23andMe plans to cut its workforce by 40% and end its therapeutics program in an effort to cut costs, the company announced Monday.

Lunchables are being pulled from school menus throughout the United States, after food manufacturer Kraft Heinz announced Tuesday that demand for the meal kits has dropped.

Raghunandan Mathur, Senior Systems Engineer, NEC, discusses now with modern day programming frameworks designed around the paradigms of scalar architectures and vector-like extensions, many present-day programmers expect a major learning […]

The post Ease of programming on NEC’s Vector Engine or SX-Aurora TSUBASA appeared first on HPCwire.

Genetic-testing lab 23andMe plans to cut its workforce by 40% and end its therapeutics program in an effort to cut costs, the company announced Monday.

Lunchables are being pulled from school menus throughout the United States, after food manufacturer Kraft Heinz announced Tuesday that demand for the meal kits has dropped.

NASA said on Tuesday that it will restart its Mentor-Protégé Program for contractors on Friday to expand commercial markets with eligible small businesses.

One Montana nonprofit tries to build connections between rural and urban students with exchange program.

Montana's highest court has struck down a tuition tax-credit program which, as enacted by that state's legislature, allowed tuition scholarships to benefit students at private religious schools as well as secular schools.

Small groups of Portland youngsters gathered in gardens, played with plant-based dyes, and cooked up vegan meals as part of Camp ELSO's mission to foster STEM learning for students of color.

An Ohio appellate court struck down a district's policy allowing staff members to carry concealed weapons in school with 24 hours of "active shooter/killer training."

The state's "Influence 100" project includes a leadership development program that will give aspiring district leaders a hands-on opportunity to work through an equity issue in their home districts.

The decision was based on how the voucher-like program is financed, not on the program itself, which is unprecedented in its scope.

The Trump administration backs three families seeking to require the state of Maine to pay tuition for their children to attend religious high schools.

A court said legislators violated the state's constitution when they passed a law that targeted specific areas to be included in the program without local consent.

A budget amendment will provide funds to develop a teacher incentive program in rural areas.

State lawmakers must create a plan to improve rural schools in response to a 2014 state Supreme Court ruling.