Note left behind blamed the leader

Medical staff and their kin talk about sacrifices they are willingly making for each other and the nation

Dr Zahid Abdul Majeed, a critical care specialist at AIIMS recently saved a critically-ill patient suffering from Covid-19 while putting his own life at risk of contracting the infection. He took off his protective goggles to re-intubate a patient keeping in mind the imminent death of the patient if he failed. Dr Zahid has now been advised quarantine for 14 days.

Honorary doctorate for new BGS director  Agg-Net

Fracking firm Cuadrilla signs secret deal with geological agency to 'destroy confidential documents'  iNews

The crystal structure of title salt, C22H46N42+·2NO3−·2H2O, has been determined using synchrotron radiation at 220 K. The structure determination reveals that protonation has occurred at diagonally opposite amine N atoms. The asymmetric unit contains half a centrosymmetric dication, one nitrate anion and one water mol­ecule. The mol­ecular dication, C22H46N42+, together with the nitrate anion and hydrate water mol­ecule are involved in an extensive range of hydrogen bonds. The mol­ecule is stabilized, as is the conformation of the dication, by forming inter­molecular N—H⋯O, O—H⋯O, together with intra­molecular N—H⋯N hydrogen bonds.

The title compound, C15H22N4O5S, was prepared via alkyl­ation of 3-(chloro­meth­yl)-5-(pentan-3-yl)-1,2,4-oxa­diazole in anhydrous dioxane in the presence of tri­ethyl­amine. The thia­diazine ring has an envelope conformation with the S atom displaced by 0.4883 (6) Å from the mean plane through the other five atoms. The planar 1,2,4-oxa­diazole ring is inclined to the mean plane of the thia­diazine ring by 77.45 (11)°. In the crystal, mol­ecules are linked by C—H⋯N hydrogen bonds, forming chains propagating along the b-axis direction. Hirshfeld surface analysis and two-dimensional fingerprint plots have been used to analyse the inter­molecular contacts present in the crystal. Mol­ecular docking studies were use to evaluate the title compound as a potential system that inter­acts effectively with the capsid of the Hepatitis B virus (HBV), supported by an experimental in vitro HBV replication model.

A combined biophysical approach was applied to map gas-docking sites within murine neuroglobin (Ngb), revealing snapshots of events that might govern activity and dynamics in this unique hexacoordinate globin, which is most likely to be involved in gas-sensing in the central nervous system and for which a precise mechanism of action remains to be elucidated. The application of UV–visible microspectroscopy in crystallo, solution X-ray absorption near-edge spectroscopy and X-ray diffraction experiments at 15–40 K provided the structural characterization of an Ngb photolytic intermediate by cryo-trapping and allowed direct observation of the relocation of carbon monoxide within the distal heme pocket after photodissociation. Moreover, X-ray diffraction at 100 K under a high pressure of dioxygen, a physiological ligand of Ngb, unravelled the existence of a storage site for O2 in Ngb which coincides with Xe-III, a previously described docking site for xenon or krypton. Notably, no other secondary sites were observed under our experimental conditions.

Scientists and local dive operators first noticed coral bleaching in the waters surrounding Isla Colon, in Panama’s Bocas del Toro province in July. Smithsonian staff scientist Nancy Knowlton and colleagues documented an extensive bleaching event in late September.

The post Coral bleaching event caused by warming ocean waters is documented in Panama appeared first on Smithsonian Insider.

For two weeks the team recorded and documented the community’s elders, families and llamas along a pilgrimage of remembrance in Pisaq, Peru.

The post American Indian Museum launches Chawaytiri documentation project in Peru appeared first on Smithsonian Insider.

The awarded film features STRI marine biologist Héctor M. Guzman diving with a group of five whale sharks while traveling in the Tropical Eastern Pacific. In the video, Guzmán tags a radiotransmitter to one of the sharks in order to follow its voyages.

The post Whale sharks featured in award-winning documentary following the work of Tropical Research Institute’s Héctor Guzman appeared first on Smithsonian Insider.

The post What will invasive round goby fish do to Great Lakes streams? Join SERC post doc Matt Kornis and find out. appeared first on Smithsonian Insider.

The post Kepler 11: A Six-Planet Sonata by Alex Parker, postdoctoral researcher at the Harvard–Smithsonian Center for Astrophysics appeared first on Smithsonian Insider.

The Encyclopedia of Life is an unprecedented global effort to document all 1.8 million named species of animals, plants and other forms of life on Earth. For the first time in the history of the planet, scientists, students, and citizens will have multi-media access to all known living species, even those that have just been discovered. The Field Museum of Natural History, Harvard University, Marine Biological Laboratory, Smithsonian Institution, and Biodiversity Heritage Library joined together to initiate the project, bringing together species and software experts from across the world. Lean more at www.eol.org

The post The Encyclopedia of Life is a global effort to document all 1.8 million named species of animals, plants and other life forms on Earth appeared first on Smithsonian Insider.

Coastal marine environments are impacted by human disturbance. Dock pilings allow MarineGEO researchers to study these impacts in a standardized way around the world to […]

The post The incredible marine diversity under boat docks appeared first on Smithsonian Insider.

The National Research Council today released its assessment of U.S. doctoral programs, which includes data on over 5,000 programs in 62 fields at 212 universities nationwide.

A new report by the National Academies of Sciences, Engineering, and Medicine proposes a strategy that the U.S. Environmental Protection Agency (EPA) should use to evaluate the evidence of adverse human health effects from low doses of exposure to chemicals that can disrupt the endocrine system.

Director Michael Apted (L) with Larry Mantle in the AirTalk studio.

This past Wednesday on "AirTalk," film director Michael Apted came in to talk with us about his eighth documentary in the series that's followed the lives of 13 people, beginning in 1964 when the kids were seven.  They've shared their stories with Apted every seven years, and he's clearly invested a lot of emotion into this project.

"56 Up" is wonderful for how it shows the mid-life evolution of the participants.  Apted includes scenes from earlier interviews, so that we see what aspects of today's 56-year-olds were present in childhood and what turns their lives have made over these years. 

"56 Up" is showing at the Nuart in West Los Angeles, and Apted will be doing Q-and-A at some of the screenings.

This content is from Southern California Public Radio. View the original story at SCPR.org.

Circus of Books storefront.; Credit: Netflix/Circus Of Books (2020)

Rachel Mason had, to a certain extent, the normal upbringing you’d imagine a family of five with small business owner parents would have. But in her documentary, ‘Circus of Books’, she pulls the curtain on the double-life her parents led as modest business owners and pillars of the LGBTQ community.

Karen and Barry Mason established West Hollywood’s Circus of Books on Santa Monica Boulevard in the 1980s. What seemed like an unassuming bookstore was actually a gay porn shop that became an institution in the LGBTQ community during a time when homosexuality was still largely unaccepted. The store was far from being a “bookstore with a circus theme”. The Los Angeles-based shop was the central hub for gay pornography around the country, once one of the main distributors for adult films. 

While the store was becoming a home for gay culture and pride, the Masons largely kept their business a secret from colleagues, friends, family, even their own children. It’s a central conflict that Rachel Mason explores throughout the film as the daughter of two shop owners caught between the pressures of maintaining a traditional family image and making a living as gay pornography distributors.

Today on FilmWeek, we’re joined by ‘Circus of Books’ director Rachel Mason for a conversation on her documentary and the experience of creating a film with her parents and their secret as the subject.

‘Circus Of Books’ is currently streaming on Netflix. For more on the film from LAist’s Mike Roe, click here.

Guest:

Rachel Mason, director of the Netflix documentary ‘Circus of Books’ and daughter of Circus of Books owners Karen and Barry Mason; she tweets @RachelMasonArt

This content is from Southern California Public Radio. View the original story at SCPR.org.

A still from "Spaceship Earth".; Credit: Neon/"Spaceship Earth" (2020)

Two months is a long time to be quarantined in one place. Just ask, well, pretty much anyone in the era of COVID-19. But imagine if you were quarantined for two years instead of two months, all in the name of science, and it was by choice!

In 1991, eight researchers did exactly that in Oracle, Arizona as part of a first-of-its-kind mission called BIOSPHERE 2. No, there was no failed BIOSPHERE 1 mission -- BIOSPHERE 1 is planet Earth. The mission’s goal was to create a living ecosystem inside a massive glass and steel facility to show that human life could be sustained in outer space. The idea was that whenever humanity finally did gain the ability to travel deeper into space and colonize another planet, a biosphere would need to be built first so that life could be sustained. But what started as a science experiment quickly evolved into a cultural phenomenon, and while some watched with bated breath to see whether the researchers could really create a living ecosystem in a controlled environment, others saw the project and those who were involved as a cult of sorts. Director Matt Wolf explores BIOSPHERE 2  the researchers (“biospherians”) who carried the mission out, what ultimately happened and the good and bad ways in which it became a cultural phenomenon.

Today on FilmWeek, “The Frame” host John Horn talks with Wolf about the making of the film and what can be learned from the biospherians about our current situation staying at home because of COVID-19.

Guest:

Matt Wolf, director of the documentary “Spaceship Earth"

This content is from Southern California Public Radio. View the original story at SCPR.org.

The company on Wednesday announced systems integration (SI) capabilities including consulting, agile devOps, cloud migration, cloud capacity optimization and the Future Mode of Operation aimed at taking the communications industry to the cloud at an accelerated pace.

There has been an established increase in reproductive disorders and other hormonal diseases, according to a recent European Environment Agency (EEA) report. The report documents a growing body of research that indicates this increase is influenced by growing levels of chemical pollutants in the environment known as endocrine disrupting chemicals (EDCs).

Endocrine disrupting chemicals (EDCs) can interfere with the hormonal systems of both humans and wildlife. New research quantifying EDCs in marine environments in Greece found concentrations which present significant risks to sediment-dwelling organisms.

A growing body of evidence suggests that endocrine-disrupting compounds (EDCs) are contributing to declines in fertility. This case-control study found that EDCs were associated with changes to sex hormones and risk of subfertility in men. The researchers say environmental levels of these chemicals should be reduced to protect male fertility.

Researchers have recommended that fish from some sections of the River Po and the River Lambro, one of the Italian River Po tributaries, should not be eaten due to high levels of some endocrine-disrupting chemicals in the river sediments and fish. This recommendation is based on an extensive update regarding pollution levels of such substances in the rivers.

Bisphenol A (BPA) is a chemical that is widespread in the environment. Researchers reviewed and critically discussed the sources and routes of human exposure to chlorinated derivatives (ClxBPA) and alternatives to BPA (BPF, BPS), as well as their metabolism, toxicity and concentrations in human tissues. The researchers suggest BPA alternatives and derivatives may have similar effects, and provide directions for future research.

Researchers in Spain have analysed waste water to calculate levels of exposure to phthalates in individuals. The calculations showed that levels of four types of phthalate exceeded safe daily limits in some of the sites studied, with levels of exposure in children being of particular concern. Using the results of waste-water analysis in this way can identify areas where action may need to be taken to lower exposure.

Personal Care Products (PCPs) are of increasing global concern, as thousands of tonnes enter the environment every year. Similar to persistent organic pollutants (POPs), some substances used in PCPs are toxic, persist in the environment and accumulate in the bodies of organisms that take them in. This study focused on the presence of ultraviolet filters (UV-Fs) (used in PCPs such as sunscreens and cosmetics) in the unhatched eggs of wild birds.

Fuel spillages and leaks from petroleum storage facilities can lead to serious pollution of soils and underground water. In a recent study, two strains of Rhodococcus bacteria were found to be effective at degrading a number of petroleum hydrocarbons and thus helping clean up contaminated sites.

“Brexit is costing us lives”

Club doctors are reported to have expressed concerns about the Premier League's Project Restart proposals, which aim to have clubs back training in small groups within the next two weeks.

Cancer-causing human papilloma virus, or HPV, can be spread through kissing and oral sex.

What good can an additional serving of fruit or vegetables a day do?

The new policy at Dignity Health Mercy Medical Center in Merced builds trust and community, and the patients are seeing the results.

Chris Paine's 'Revenge of the Electric Car' gets a wide theatrical release this fall. It's a close-up and dramatic look at the high-stakes EV rollout.

A nearly 70-foot-long dock floated onto an Oregon beach after being torn loose from a fishing port in Japan after the tsunami.

Fisherman discovered a dock from the Japanese tsunami off the shores of Hawaii.

Documentary on coal mining’s effect on Appalachian communities premieres in West Virginia this Saturday.

Anxiety and fear give way to joy and awe when we tune into scenes of the natural world, finds a study commissioned by BBC, makers of "Planet Earth II."

"It's 'Just' Anxiety," a film by Susan Polis Schutz, shows how the mental health issue manifests itself in various people and how they treated it successfully.