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Die Rhinoskopie und ihr Werth für die ärztliche Praxis : ein monographischer Versuch / von Friedrich Semeleder.

Leipzig : W. Engelmann, 1862.




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Die Serumtherapie bei Diphtherie in Theorie und Praxis : nach eignen Beobachtungen in der Chirurgischen Klinik zu Halle / von Kurt Müller.

Halle : M. Niemeyer, 1895.




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Die specielle Therapie / nach den hinterlassenen Papieren des verstorbenen D. Aug. Gottl. Richter ... ; herausgegeben von D. Georg. Aug. Richter.

Wien : Doll, 1817-




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Die Therapie an den Wiener Kliniken : ein Verzeichniss der wichtigsten, an denselben gebräuchlichen Heilmethoden und Recepte / von Ernst Landesmann.

Leipzig : F. Deuticke, 1891.




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Die Therapie der Magen-und Darmerkrankungen / von Carl Wegele.

Jena : Fischer, 1905.




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Die thiericshen [i.e. thierischen] Parasiten des Menschen : im Anhang Tabellen enthaltend die wichtigsten Merkmale der Parasiten, Diagnosen und Angaben über die Therapie der durch die Parasiten hervorgerufenen pathologischen Erscheinungen / bearbeite

Cassel : T. Fischer, 1884.




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Die Trichinenepidemie zu Hedersleben : Beitrag zur Pathologie und Therapie der Trichinenkrankheiten / von F. Kratz.

Leipzig : W. Engelmann, 1866.




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Die Tuberkulose, ihre Aetiologie, Prophylaxis und Therapie : nach klinischen Erfahrungen und Versuchen / von J. Goldschmidt.

Leipzig : Vogel, 1904.




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Die Verwertung der Fäcesuntersuchung für die Diagnose und Therapie der Säuglingsdarmkatarrhe nach Biedert : auf Grund zahlreicher eigener Beobachtungen für den praktischen Gebrauch / von Paul Selter.

Stuttgart : Enke, 1904.




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Die Wechselbeziehungen in der menschlichen Pathologie und Therapie : eine allgemein-medizinische Studie / von S. Laache.

Stuttgart : Enke, 1905.




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Die Zählung der Blutkörperchen und deren Bedeutung für Diagnose und Therapie / von Emil Reinert.

Leipzig : F.C.W. Vogel, 1891.




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Digestion and indigestion : proper and improper feeding in health and disease / by A. Lockhart Gillespie.

Edinburgh : MacNiven & Wallace, 1896.




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Dissertation sur les affections locales des nerfs / par Pierre-Jules Descot.

Paris : chez Mlle Delaunay, 1825.




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Dr. H. Helfft's Handbuch der Balneotherapie : practischer Leitfaden bei Verordnung der Mineralquellen, Molken, Seebäder, klimatischen Kurorte, &c. / mit Benutsung der vom Verfasser hinterlassenen Notizen neu bearbeitet und herausgegeben von E

Berlin : A. Hirschwald, 1870.




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Du choix de l'intervention dans les affections des annexes de l'uterus / par Pierre Camescasse.

Paris : G. Steinheil, 1893.




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The effect of the cold weather in the early part of 1895 on the admission of medical cases into the Royal Edinburgh Infirmary. With a note on some earlier periods of severe weather / by A. Lockhart Gillespie.

London : Kenny & Co, [1895?]




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Einleitung in die technische Mikroskopie nebst mikroskopisch-technischen Untersuchungen : für Techniker, Chemiker, und zum Gebrauche an polytechnischen Schulen / von Julius Wiesner.

Wien : W. Braumuller, 1867.




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Embryologie und Infections-Krankheits-Uebertragung, sowie die Blutserum-Therapie / von Heinrich Janke.

Berlin : Heuser, 1894.




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Encyklopaedie der Therapie / herausgegeben von Oscar Liebreich ; unter Mitwirkung von Martin Mendelsohn und Arthur Würzburg.

Berlin : A. Hirschwald, 1896-1900.




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Endoskopie und endoskopische Therapie der Krankheiten der Harnrohre und Blase / von Emil Burckhardt.

Tubingen : H. Laupp, 1889.




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Epidemic of scarlet fever at Donaldson's Hospital during the autumn and winter of 1861 / by James D. Gillespie.

Edinburgh : Oliver & Boyd, 1862.




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Alaska Reporter Will Study Rural Education as 2nd Chronister Fellowship Recipient

Victoria Petersen, of the Peninsula Clarion on the Kenai Peninsula, will report on the challenges of rural education, especially in a state as vast as Alaska.




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Saint Matthew. Engraving by N. Dorigny, 1707, after D. Zampieri, il Domenichino.

[Rome] : [Nicolaus Dorigny?], Sup. perm. 1707.




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Fortitude with her attributes. Engraving by J. Frey, 1725, after D. Zampieri, il Domenichino.

[Rome], [1725]




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Justice with her attributes. Engraving by J. Frey, 1725, after D. Zampieri, il Domenichino.

[Rome], [1725]




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The device of the Emperor Charles V surrounding initials of the artist Pieter Coecke van Aelst. Process print, 1873.




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PHT Morning Skate: Pietrangelo’s future; underrated Bjorkstrand

Friday's collection of links.




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Marketplace, power, prestige : the healthcare professions' struggle for recognition (19th-20th century) / edited by Pierre Pfütsch.

Stuttgart : Franz Steiner Verlag, 2019.




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Tierische Drogen im 18. Jahrhundert im Spiegel offizineller und nicht offizineller Literatur und ihre Bedeutung in der Gegenwart / Katja Susanne Moosmann ; mit einem Geleitwort von Christoph Friedrich.

Stuttgart : In Kommission: Wissenschaftliche Verlagsgesellschaft, 2019.




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Rx: 3 x/week LAAM : alternative to methadone / editors, Jack D. Blaine, Pierre F. Renault.

Rockville, Maryland : The National Institute on Drug Abuse, 1976.




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Narcotic antagonists : naltrexone : progress report / editors, Demetrios Julius, Pierre Renault.

Rockville, Maryland : U.S. Dept. of Health, Education, and Welfare, Public Health Service, Alcohol, Drug Abuse and Mental Health Administration, 1976.




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Integrating behavioral therapies with medications in the treatment of drug dependence / editors, Lisa Simon Onken, Jack D. Blaine, John J. Boren.

Rockville, Maryland : National Institute on Drug Abuse, 1995.




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Estimating piecewise monotone signals

Kentaro Minami.

Source: Electronic Journal of Statistics, Volume 14, Number 1, 1508--1576.

Abstract:
We study the problem of estimating piecewise monotone vectors. This problem can be seen as a generalization of the isotonic regression that allows a small number of order-violating changepoints. We focus mainly on the performance of the nearly-isotonic regression proposed by Tibshirani et al. (2011). We derive risk bounds for the nearly-isotonic regression estimators that are adaptive to piecewise monotone signals. The estimator achieves a near minimax convergence rate over certain classes of piecewise monotone signals under a weak assumption. Furthermore, we present an algorithm that can be applied to the nearly-isotonic type estimators on general weighted graphs. The simulation results suggest that the nearly-isotonic regression performs as well as the ideal estimator that knows the true positions of changepoints.




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Branch and Bound for Piecewise Linear Neural Network Verification

The success of Deep Learning and its potential use in many safety-critical applicationshas motivated research on formal verification of Neural Network (NN) models. In thiscontext, verification involves proving or disproving that an NN model satisfies certaininput-output properties. Despite the reputation of learned NN models as black boxes,and the theoretical hardness of proving useful properties about them, researchers havebeen successful in verifying some classes of models by exploiting their piecewise linearstructure and taking insights from formal methods such as Satisifiability Modulo Theory.However, these methods are still far from scaling to realistic neural networks. To facilitateprogress on this crucial area, we exploit the Mixed Integer Linear Programming (MIP) formulation of verification to propose a family of algorithms based on Branch-and-Bound (BaB). We show that our family contains previous verification methods as special cases.With the help of the BaB framework, we make three key contributions. Firstly, we identifynew methods that combine the strengths of multiple existing approaches, accomplishingsignificant performance improvements over previous state of the art. Secondly, we introducean effective branching strategy on ReLU non-linearities. This branching strategy allows usto efficiently and successfully deal with high input dimensional problems with convolutionalnetwork architecture, on which previous methods fail frequently. Finally, we proposecomprehensive test data sets and benchmarks which includes a collection of previouslyreleased testcases. We use the data sets to conduct a thorough experimental comparison ofexisting and new algorithms and to provide an inclusive analysis of the factors impactingthe hardness of verification problems.




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Flexible, boundary adapted, nonparametric methods for the estimation of univariate piecewise-smooth functions

Umberto Amato, Anestis Antoniadis, Italia De Feis.

Source: Statistics Surveys, Volume 14, 32--70.

Abstract:
We present and compare some nonparametric estimation methods (wavelet and/or spline-based) designed to recover a one-dimensional piecewise-smooth regression function in both a fixed equidistant or not equidistant design regression model and a random design model. Wavelet methods are known to be very competitive in terms of denoising and compression, due to the simultaneous localization property of a function in time and frequency. However, boundary assumptions, such as periodicity or symmetry, generate bias and artificial wiggles which degrade overall accuracy. Simple methods have been proposed in the literature for reducing the bias at the boundaries. We introduce new ones based on adaptive combinations of two estimators. The underlying idea is to combine a highly accurate method for non-regular functions, e.g., wavelets, with one well behaved at boundaries, e.g., Splines or Local Polynomial. We provide some asymptotic optimal results supporting our approach. All the methods can handle data with a random design. We also sketch some generalization to the multidimensional setting. To study the performance of the proposed approaches we have conducted an extensive set of simulations on synthetic data. An interesting regression analysis of two real data applications using these procedures unambiguously demonstrates their effectiveness.




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Item 01: Notebooks (2) containing hand written copies of 123 letters from Major William Alan Audsley to his parents, ca. 1916-ca. 1919, transcribed by his father. Also includes original letters (2) written by Major Audsley.




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A Conversation with Piet Groeneboom

Geurt Jongbloed.

Source: Statistical Science, Volume 34, Number 1, 156--168.

Abstract:
Petrus (Piet) Groeneboom was born in Scheveningen in 1941 and grew up in Voorburg. Both villages are located near The Hague in The Netherlands; Scheveningen actually being part of The Hague. He attended the gymnasium of the Huygens lyceum. In 1959, he entered the University of Amsterdam, where he studied psychology. After his “candidate” exam (comparable to BSc) in 1963, he worked at the psychological laboratory of the University of Amsterdam until 1966. In 1965, he took up mathematics as a part-time study. After having obtained his master’s degree in 1971, he had a position at the psychological laboratory again until 1973, when he was appointed to the Mathematical Center in Amsterdam. There, he wrote between 1975 and 1979 his Ph.D. thesis with Kobus Oosterhoff as advisor, graduating in 1979. After a period of two years as visiting professor at the University of Washington (UW) in Seattle, Piet moved back to the Mathematical Center until he was appointed full professor of statistics at the University of Amsterdam in 1984. Four years later, he moved to Delft University of Technology where he became professor of statistics and stayed until his retirement in 2006. Between 2000 and 2006 he also held a part-time professorship at the Vrije Universiteit in Amsterdam. From 1999 till 2013 he was Affiliate Professor at the statistics department of UW, Seattle. Apart from being visiting professor at the UW in Seattle, he was also visiting professor at Stanford University, Université Paris 6 and ETH Zürich. Piet is well known for his work on shape constrained statistical inference. He worked on asymptotic theory for these problems, created algorithms to compute nonparametric estimates in such models and applied these models to real data. He also worked on interacting particle systems, extreme value analysis and efficiency theory for testing procedures. Piet (co-)authored four books and 64 papers and served as promotor of 13 students. He is the recipient of the 1985 Rollo Davidson prize, a fellow of the IMS and elected member of the ISI. In 2015, he delivered the Wald lecture at the Joint Statistical Meeting in Montreal. Piet and his wife Marijke live in Naarden. He has two sons, Thomas and Tim, and (since June 12, 2018) one grandson, Tarik. This conversation was held at Piet’s house in Naarden, on February 28 and April 24, 2018.




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Lego Pieces Could Last for 1,300 Years in Marine Environments

The extent of the toy’s durability came as a 'surprise' to researchers behind a new study




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Van Gogh Masterpiece Stolen From Dutch Museum Shuttered by COVID-19

Thieves pilfered "The Parsonage Garden at Nuenen in Spring 1884" from the Singer Laren in the early hours of Monday morning




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Museums Challenged to Showcase 'Creepiest Objects' Deliver Stuff of Nightmares

We’re really, really sorry




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Norway Lobsters Crush Ocean Plastic Into Even Smaller Pieces—and That's Bad

The crustaceans' guts pulverize plastics into tiny bits that can be consumed by even smaller creatures at the base of the ocean food chain




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Scammers taking advantage of rising demand for pandemic puppies

The COVID-19 pandemic has meant a spike in demand for puppies and an opportunity for scammers who are charging inflated prices for dogs not ready to be adopted out or with missing or bogus papers.



  • News/Canada/Toronto

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Canmore mourns unusual friendly elk who befriended dogs and magpies

Some residents of Canmore, Alta., are mourning the death of an unusual elk that went by the name of Marvin. He was known to frequent backyards and hang out with pets.



  • News/Canada/Calgary

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13 cases of COVID-19 linked to curling bonspiel attended by doctors from across western Canada

The bonspiel took place in Edmonton March 11-14, starting the same day COVID-19 was declared a global pandemic.



  • News/Canada/Saskatchewan

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Making broken pieces beautiful

By offering a creative class for women, an OM worker finds ways to transform broken tiles into art and make relationships where she can share God’s truth.




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Ainsley Harriott: Has there ever been a happier man on TV?

Lauren Taylor catches up with the popular TV chef, after he explores the Med for his new show and cookbook.




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Groupies: muses, victims or both?

THE 2000 film Almost Famous told the love story of a schoolboy writer tracking a rock band and falling for a teenage girl – who happens to be a groupie. Or was she?




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Figueres: “Estados Unidos pierde competitividad saliendo del Acuerdo de París”

Source: EFE Verde - La ex secretaria de cambio climático de la ONU que alcanzó el Acuerdo de París y actual directora del proyecto Misión 2020, Christiana Figueres, subraya que EE.UU. "se queda rezagado y pierde competitividad" abandonando el Acuerdo de París y cediendo a otros países el liderazgo de la economía baja en carbono.




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Use of Antihypotensive Therapies in Extremely Preterm Infants

Extremely preterm infants who receive antihypotensive therapy have worse outcomes than untreated infants. The reasons for this are not clear. High-quality randomized trials have not been performed to date because of logistical challenges, thereby necessitating alternative methods of investigation.

Antihypotensive therapy administration was not associated with improved in-hospital outcomes for any of the 15 definitions of low blood pressure investigated. Alternative methods of deciding who to treat are needed to maximize patient benefit and minimize harm. (Read the full article)




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Unmet Needs of Siblings of Pediatric Stem Cell Transplant Recipients

The American Academy of Pediatrics has recommended that sibling donors should have an independent advocate. Defining the need for and role of this advocate is hampered by a lack of empirical data.

This study provides prospective family data regarding siblings’ experiences during HLA typing and donation pre- and posttransplantation. Most family members, including the siblings, perceive no choice in typing or donation, yet have few concerns and report positive aspects to participating. (Read the full article)