iab Stress-Induced Translational Regulation Mediated by RNA Binding Proteins: Key Links to {beta}-Cell Failure in Diabetes By diabetes.diabetesjournals.org Published On :: 2020-03-20T11:50:28-07:00 In type 2 diabetes, β-cells endure various forms of cellular stress, including oxidative stress and endoplasmic reticulum stress, secondary to increased demand for insulin production and extracellular perturbations, including hyperglycemia. Chronic exposure to stress causes impaired insulin secretion, apoptosis, and loss of cell identity, and a combination of these processes leads to β-cell failure and severe hyperglycemia. Therefore, a better understanding of the molecular mechanisms underlying stress responses in β-cells promises to reveal new therapeutic opportunities for type 2 diabetes. In this perspective, we discuss posttranscriptional control of gene expression as a critical, but underappreciated, layer of regulation with broad importance during stress responses. Specifically, regulation of mRNA translation occurs pervasively during stress to activate gene expression programs; however, the convenience of RNA sequencing has caused translational regulation to be overlooked compared with transcriptional controls. We highlight the role of RNA binding proteins in shaping selective translational regulation during stress and the mechanisms underlying this level of regulation. A growing body of evidence indicates that RNA binding proteins control an array of processes in β-cells, including the synthesis and secretion of insulin. Therefore, systematic evaluations of translational regulation and the upstream factors shaping this level of regulation are critical areas of investigation to expand our understanding of β-cell failure in type 2 diabetes. Full Article
iab Amino Acid Metabolism, {beta}-Cell Function, and Diabetes By diabetes.diabetesjournals.org Published On :: 2006-12-01 Philip NewsholmeDec 1, 2006; 55:S39-S47Section II: The Muscle and Liver Connections Full Article
iab Amylin Agonists: A Novel Approach in the Treatment of Diabetes By diabetes.diabetesjournals.org Published On :: 2004-12-01 Ole SchmitzDec 1, 2004; 53:S233-S238Section V: The Incretin Pathway Full Article
iab Risk Factors for Diabetic Peripheral Neuropathy and Cardiovascular Autonomic Neuropathy in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) Study By diabetes.diabetesjournals.org Published On :: 2020-05-01 Barbara H. BraffettMay 1, 2020; 69:1000-1010Complications Full Article
iab The Histone Methyltransferase MLL1 Directs Macrophage-Mediated Inflammation in Wound Healing and Is Altered in a Murine Model of Obesity and Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2017-09-01 Andrew S. KimballSep 1, 2017; 66:2459-2471Immunology and Transplantation Full Article
iab Effect of a Sustained Reduction in Plasma Free Fatty Acid Concentration on Intramuscular Long-Chain Fatty Acyl-CoAs and Insulin Action in Type 2 Diabetic Patients By diabetes.diabetesjournals.org Published On :: 2005-11-01 Mandeep BajajNov 1, 2005; 54:3148-3153Metabolism Full Article
iab AMPK: A Target for Drugs and Natural Products With Effects on Both Diabetes and Cancer By diabetes.diabetesjournals.org Published On :: 2013-07-01 D. Grahame HardieJul 1, 2013; 62:2164-2172Perspectives in Diabetes Full Article
iab The High-Fat Diet-Fed Mouse: A Model for Studying Mechanisms and Treatment of Impaired Glucose Tolerance and Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2004-12-01 Maria Sörhede WinzellDec 1, 2004; 53:S215-S219Section V: The Incretin Pathway Full Article
iab Muscle Weakness: A Progressive Late Complication in Diabetic Distal Symmetric Polyneuropathy By diabetes.diabetesjournals.org Published On :: 2006-03-01 Christer S. AndreassenMar 1, 2006; 55:806-812Complications Full Article
iab MicroRNA Networks in Pancreatic Islet Cells: Normal Function and Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2020-05-01 Lena EliassonMay 1, 2020; 69:804-812Small Noncoding RNAs in Diabetes Full Article
iab Sugar, Uric Acid, and the Etiology of Diabetes and Obesity By diabetes.diabetesjournals.org Published On :: 2013-10-01 Richard J. JohnsonOct 1, 2013; 62:3307-3315Perspectives in Diabetes Full Article
iab Pancreas Pathology of Latent Autoimmune Diabetes in Adults (LADA) in Patients and in a LADA Rat Model Compared With Type 1 Diabetes By diabetes.diabetesjournals.org Published On :: 2020-04-01 Anne JörnsApr 1, 2020; 69:624-633Islet Studies Full Article
iab The Incretin Approach for Diabetes Treatment: Modulation of Islet Hormone Release by GLP-1 Agonism By diabetes.diabetesjournals.org Published On :: 2004-12-01 Jens Juul HolstDec 1, 2004; 53:S197-S204Section V: The Incretin Pathway Full Article
iab Mechanisms of {beta}-Cell Death in Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2005-12-01 Marc Y. DonathDec 1, 2005; 54:S108-S113Section III: Inflammation and beta-Cell Death Full Article
iab Type 2 Diabetes: Demystifying the Global Epidemic By diabetes.diabetesjournals.org Published On :: 2017-06-01 Ranjit UnnikrishnanJun 1, 2017; 66:1432-1442Perspectives in Diabetes Full Article
iab Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet-Induced Obesity and Diabetes in Mice By diabetes.diabetesjournals.org Published On :: 2008-06-01 Patrice D. CaniJun 1, 2008; 57:1470-1481Metabolism Full Article
iab Environmental Triggers and Determinants of Type 1 Diabetes By diabetes.diabetesjournals.org Published On :: 2005-12-01 Mikael KnipDec 1, 2005; 54:S125-S136Section IV: Polygenic Disease and Environment Full Article
iab Insulin Resistance and Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2012-04-01 Roy TaylorApr 1, 2012; 61:778-779Commentary Full Article
iab Predictors of Postpartum Diabetes in Women With Gestational Diabetes Mellitus By diabetes.diabetesjournals.org Published On :: 2006-03-01 Kristian LöbnerMar 1, 2006; 55:792-797Pathophysiology Full Article
iab PPARA Polymorphism Influences the Cardiovascular Benefit of Fenofibrate in Type 2 Diabetes: Findings From ACCORD-Lipid By diabetes.diabetesjournals.org Published On :: 2020-04-01 Mario Luca MorieriApr 1, 2020; 69:771-783Genetics/Genomes/Proteomics/Metabolomics Full Article
iab Intense Exercise Has Unique Effects on Both Insulin Release and Its Roles in Glucoregulation: Implications for Diabetes By diabetes.diabetesjournals.org Published On :: 2002-02-01 Errol B. MarlissFeb 1, 2002; 51:S271-S283Section 6: Pusatile and Phasic Insulin Release in Normal and Diabetic Men Full Article
iab Vitamin D Receptor Overexpression in {beta}-Cells Ameliorates Diabetes in Mice By diabetes.diabetesjournals.org Published On :: 2020-05-01 Meritxell MorróMay 1, 2020; 69:927-939Islet Studies Full Article
iab The Rise of Childhood Type 1 Diabetes in the 20th Century By diabetes.diabetesjournals.org Published On :: 2002-12-01 Edwin A.M. GaleDec 1, 2002; 51:3353-3361Perspectives in Diabetes Full Article
iab ACE2 and Diabetes: ACE of ACEs? By diabetes.diabetesjournals.org Published On :: 2010-12-01 Daniel BatlleDec 1, 2010; 59:2994-2996Commentaries Full Article
iab Effect of a High-Protein, Low-Carbohydrate Diet on Blood Glucose Control in People With Type 2 Diabetes By diabetes.diabetesjournals.org Published On :: 2004-09-01 Mary C. GannonSep 1, 2004; 53:2375-2382Pathophysiology Full Article
iab Mechanisms of Pancreatic {beta}-Cell Death in Type 1 and Type 2 Diabetes: Many Differences, Few Similarities By diabetes.diabetesjournals.org Published On :: 2005-12-01 Miriam CnopDec 1, 2005; 54:S97-S107Section III: Inflammation and beta-Cell Death Full Article
iab Autoantibodies in Diabetes By diabetes.diabetesjournals.org Published On :: 2005-12-01 Catherine PihokerDec 1, 2005; 54:S52-S61Section II: Type 1-Related Forms of Diabetes Full Article
iab Low-Grade Systemic Inflammation and the Development of Type 2 Diabetes: The Atherosclerosis Risk in Communities Study By diabetes.diabetesjournals.org Published On :: 2003-07-01 Bruce B. DuncanJul 1, 2003; 52:1799-1805Pathophysiology Full Article
iab Five Stages of Evolving Beta-Cell Dysfunction During Progression to Diabetes By diabetes.diabetesjournals.org Published On :: 2004-12-01 Gordon C. WeirDec 1, 2004; 53:S16-S21Section I: Insulin Resistance-Beta-Cell Connection in Type 2 Diabetes Full Article
iab From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus By diabetes.diabetesjournals.org Published On :: 2009-04-01 Ralph A. DeFronzoApr 1, 2009; 58:773-795Banting Lecture Full Article
iab Diabetes in China: Epidemiology and Genetic Risk Factors and Their Clinical Utility in Personalized Medication By diabetes.diabetesjournals.org Published On :: 2018-01-01 Cheng HuJan 1, 2018; 67:3-11Perspectives in Diabetes Full Article
iab The Pathobiology of Diabetic Complications: A Unifying Mechanism By diabetes.diabetesjournals.org Published On :: 2005-06-01 Michael BrownleeJun 1, 2005; 54:1615-1625Banting Lecture 2004 Full Article
iab Latent Autoimmune Diabetes in Adults: Definition, Prevalence, {beta}-Cell Function, and Treatment By diabetes.diabetesjournals.org Published On :: 2005-12-01 Gunnar StenströmDec 1, 2005; 54:S68-S72Section II: Type 1-Related Forms of Diabetes Full Article
iab Differentiation of Diabetes by Pathophysiology, Natural History, and Prognosis By diabetes.diabetesjournals.org Published On :: 2017-02-01 Jay S. SkylerFeb 1, 2017; 66:241-255Perspectives in Diabetes Full Article
iab Diabetes Core Update – July 2019 By diabetescoreupdate.libsyn.com Published On :: Wed, 19 Jun 2019 21:28:16 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Prognostic Significance of Unrecognized MI in Patients with Diabetes Driving and Glucose Variability Fournier Gangrene Associated with SGLT-2 Inhibitors Faster Acting Insulin Aspart vs. Insulin Aspart Sleep and Glycemia Flash Glucose Monitoring and Effect on Glycemic Control For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – August 2019 By diabetescoreupdate.libsyn.com Published On :: Wed, 24 Jul 2019 18:30:00 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Dapagliflozin Plus Saxagliptin Add-on Therapy Compared with Insulin Dulaglutide and Cardiovascular Outcomes in Type 2 Diabetes (REWIND) Mediterranean Diet and the Need for Glucose- Lowering Medications Oral Semaglutide versus Subcutaneous Liraglutide and Placebo Vitamin E and Pioglitazone for Nonalcoholic Steatohepatitis in Patients with Type 2 Diabetes Durability of Insulin Degludec plus Liraglutide versus Insulin Glargine U100 For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – September 2019 By diabetescoreupdate.libsyn.com Published On :: Sat, 24 Aug 2019 19:00:00 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Oral Semaglutide Monotherapy in Type 2 Diabetes Lifestyle Counseling and Long-term Clinical Outcomes Economic Burden of Diabetes in the United States Microvascular Disease and Heart Failure with Preserved Ejection Fraction Optimal Blood Pressure Target for Patients with Type 1 Diabetes Lack of Durable Improvements in Beta-Cell Function after Medication Withdrawal in Prediabetes For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – October 2019 By diabetescoreupdate.libsyn.com Published On :: Tue, 24 Sep 2019 18:30:00 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Nasal Glucagon Incidence of type 2 diabetes in people with a history of hospitalization for major mental illness Achievement of Target A1C <7.0% after treatment with basal insulin in Randomized Controlled Trials and Clinical Practice Metformin effect on Coronary endothelial Dysfunction in prediabetic patients with stable angina Change in cardiovascular health risk and the development of type 2 diabetes and impaired fasting glucose Association between diabetes HbA1c, glycaemia and development of frailty in the elderly For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – November 2019 By diabetescoreupdate.libsyn.com Published On :: Fri, 25 Oct 2019 12:46:30 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Glycemia Reduction Approaches in Diabetes (GRADE) Trial The Effect of Disasters on Patients with Diabetes Fixed Ratio GLP-1/Basal Insulin in Patients Uncontrolled on GLP-1 Mechanisms of CV Protection for SGLT-2 Inhibitors Oral Semaglutide and Cardiovascular Outcomes Trends in Pancreatitis and Pancreatic Cancer in patients started on DPP-4 Inhibitors For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – December 2019 By diabetescoreupdate.libsyn.com Published On :: Sun, 24 Nov 2019 20:00:00 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Combination Basal Insulin/GLP-1 RA vs Basal Bolus for Persons with Very Elevated A1c Changes in Consumption of Sugary Beverages and Artificially Sweetened Beverages and the Risk of Type 2 Diabetes Oral Semaglutide vs. Placebo added to Insulin : The PIONEER 8 Trial Residual Hypertriglyceridemia and Estimated Atherosclerotic CV Risk by Stain Use in U.S. Adults with Diabetes A1c Variability and the Risk of Poor Outcomes in People with Type 2 Diabetes Oral Semaglutide vs. Empagliflozin in Persons with Type 2 Diabetes Uncontrolled on Metformin For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – January 2019 By diabetescoreupdate.libsyn.com Published On :: Thu, 26 Dec 2019 20:41:53 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Linagliptin in Older adults on Insulin Lactic Acidosis from Metformin – FDA analysis Glucagon Receptor Antagonist RV-1502 – Efficacy and Safety Early Identification of MODY SGLT-2 Inhibitors and the Development of Mycotic Infections and UTIs SFLT-2 Inhibitors in Patients with Type 1 Diabetes and the Rate of Diabetic Ketoacidosis For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – February 2019 By diabetescoreupdate.libsyn.com Published On :: Sat, 25 Jan 2020 11:33:45 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Efficacy and safety of dapagliflozin in the elderly Lactic Acidosis from Metformin – FDA analysis Economic and Clinical Burden of Nonalcoholic Steatohepatitis in Patients With Type 2 Diabetes in the United States 2019 update to: Management of hyperglycaemia in type 2 diabetes, 2018. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Transitioning to Fixed-Ratio Combination Therapy: Practical Advice General practitioner advice associated with greater physical activity in adults with type 2 diabetes Empagliflozin Effectively Lowers Liver Fat Content For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – March 2019 By diabetescoreupdate.libsyn.com Published On :: Mon, 24 Feb 2020 20:30:00 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This month we review articles on: Association of body mass index, fitness, and mortality in patients with diabetes Cognitive deficits and traditional diabetic complications in the severely obese Late Relapse of Diabetes after Bariatric Surgery Hypoglycemia in Type 1 Diabetes and Subsequent Cognitive Deficits Nutrient Induced Beta Cell Stress Topical Oxygen Therapy in the Treatment of Diabetic Foot Ulcers For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – COVID-19 UPDATE: March 2019 By diabetescoreupdate.libsyn.com Published On :: Tue, 24 Mar 2020 12:58:08 +0000 This is a special issue focusing on Covid-19 and Diabetes: Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China Clinical course and risk factors for mortality Diabetes and Hypertension: Are ACE’s, ARBs and NSAIDs OK to Use? Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Abington Jefferson Health Full Article
iab Diabetes Core Update – April 2019 By diabetescoreupdate.libsyn.com Published On :: Tue, 31 Mar 2020 15:50:29 +0000 Diabetes Core Update is a monthly podcast that presents and discusses the latest clinically relevant articles from the American Diabetes Association’s four science and medical journals – Diabetes, Diabetes Care, Clinical Diabetes, and Diabetes Spectrum. Each episode is approximately 20 minutes long and presents 5-6 recently published articles from ADA journals. Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. This issue will review: Normalization of functional beta cell capacity after weight loss in type 2 diabetes Screening for glucose intolerance and diabetes in patients with coronary artery disease Trends Prescribing Preferences for SGLT2 Inhibitors and GLP-1 Receptor Agonists, 2013–2018 Impact of a Telephone Intervention to Improve Diabetes Control on Healthcare Utilization and Cost for Adults in South Bronx, New York – Efficacy and Safety of Dapagliflozin Plus Saxagliptin Versus Insulin Glargine Over 52 Weeks as Add‐on to Metformin With or Without Sulfonylurea in Patients With Type 2 Diabetes The Association Between Poor Glycemic Control and Health Care Costs in People With Diabetes For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health Full Article
iab Diabetes Core Update: Therapeutic Inertia – April 2020 By diabetescoreupdate.libsyn.com Published On :: Tue, 14 Apr 2020 19:00:00 +0000 In this first episode of a three-part series on “Disrupting Therapeutic Inertia in Diabetes Management,” Drs. John Russell and Neil Skolnik examine a case study of a 55-year-old man with type 2 diabetes (3 years duration, A1C 8.2%). In so doing, they review six articles that define achievement gaps in reaching A1C goals and the reasons for why those gaps exist. In episodes 2 and 3 of this series, Drs. Russell and Skolnik we will look at additional causes of therapeutic inertia and solutions for overcoming it. This special three-part series on therapeutic inertia is supported by independent educational grant from Sanofi (https://www.sanofi.com). This issue will review: Achievement of target therapeutic goals in persons with T2DM Achievement of therapeutic goals from 2005 – 2015 Clinical Inertia in Newly Diagnosed Type 2 DM Clinical Inertia over Time in Type 2 DM Gap Between Efficacy in Randomized Controlled Trials and Effectiveness in Real-World Use Difference between Clinical Trial and Real-World Studies Achievement of Target A1C <7.0% in Patients Treated with Basal Insulin in RCTs and Clinical Practice For more information about each of ADA’s science and medical journals, please visit www.diabetesjournals.org. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Associate Director, Family Medicine Residency Program, Abington Jefferson Health John J. Russell, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University; Director, Family Medicine Residency Program, Chair-Department of Family Medicine, Abington Jefferson Health Full Article
iab Diabetes Core Update: Covid-19 - Planning Sick Days April 2019 By diabetescoreupdate.libsyn.com Published On :: Mon, 20 Apr 2020 23:47:13 +0000 This special issue focuses on Diabetes, Covid-19 and managing patient’s diabetes when they are sick. Recorded April 1, 2020. This podcast will cover: How do we help our patients with diabetes stay safe Helping patient negotiate safety issues in the workplace Safety Issues when people do not come in for care Managing SGLT-2 inhibitors during the pandemic Home detection and care of DKA Renewing Medications Telemedicine Visits Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Presented by: Louis Philipson, MD, PhD, ADA Past President, Medicine & Science, University of Chicago Anne Peters, MD, Diabetologist, University of Southern California Full Article
iab Diabetes Core Update: Covid-19 – Inpatient Management of Persons with Diabetes April 2019 By diabetescoreupdate.libsyn.com Published On :: Tue, 21 Apr 2020 16:44:58 +0000 This special issue focuses on Diabetes, Covid-19 and Inpatient Management. Recorded April 3, 2020. This podcast will cover: Risk with Diabetes of Covid-19 and Complications of Covid-19 Management of Hyperglycemia during Covid-19 Infection Sub-cutaneous Insulin for DKA CGM in the Hospital Setting Diabetes Education in the Hospital During Covid-19 Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Presented by: Irl Hirsch, MD, Professor of Medicine, University of Washington, Seattle Guillermo E. Umpierrez, MD, CDE, Professor of Medicine, Emory University, Atlanta Georgia Full Article
iab Diabetes Core Update: Covid-19 – Deep Dive into Medication Management April 2019 By diabetescoreupdate.libsyn.com Published On :: Wed, 22 Apr 2020 18:00:00 +0000 This special issue focuses on Diabetes, Covid-19 and Inpatient Management. Recorded April 14, 2020. This podcast will cover: Inpatient Medication Management for Persons Admitted with Diabetes Outpatient Medication Management for Persons with Diabetes Hypoglycemic Medication Management ACE and ARBs NSAIDs Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Presented by: Neil Skolnik, M.D., Professor of Family and Community Medicine, Sidney Kimmel Medical College, Thomas Jefferson University, Associate Director, Family Medicine Residency Program, Abington Jefferson Health Dr. Joshua Neumiller, Vice Chair & Allen I. White Distinguished Associate Professor of Pharmacotherapy at Washington State University Full Article
iab Diabetes Core Update: Covid-19 and Diabetes – Considerations for Health Care Professionals - April 2019 By diabetescoreupdate.libsyn.com Published On :: Thu, 23 Apr 2020 18:00:00 +0000 Diabetes Core Update: Covid-19 and Diabetes – Considerations for Health Care Professionals - April 2019 This special issue is an audio version of the American Diabetes Associations Covid-19 leadership team discussing a range of issues on Covid-19 and Diabetes. Recorded March 31, 2020. Topics include: Access to medications Effect on Diabetes Self-management Can Patients take their own Supplies if they are an inpatient in the hospital – particularly insulin pumps and CGM Considerations for Specific Hypoglycemic Medications during Inpatient Hospitalization Differences in Management for Persons with Type 1 and Type 2 Diabetes SGLT-2 inhibitors and GLP-1 Receptor Agonists use During Covid-19 Infection Diabetes and Cardiovascular Disease during Covid-19 ACEs and ARBs Stress among Healthcare Professionals Intended for practicing physicians and health care professionals, Diabetes Core Update discusses how the latest research and information published in journals of the American Diabetes Association are relevant to clinical practice and can be applied in a treatment setting. Presented by: Robert Eckel, MD ADA President, Medicine & Science University of Colorado Mary de Groot, PhD ADA President, Health Care & Education Indiana University Irl Hirsch, MD University of Washington Anne Peters, MD University of Southern California Louis Philipson, MD, PhD ADA Past President, Medicine & Science University of Chicago Neil Skolnik, MD Abington Jefferson Health Full Article