VMXm joins the suite of operational macromolecular crystallography beamlines at Diamond Light Source. It has been designed to optimize rotation data collections from protein crystals less than 10 µm and down to below 1 µm in size. The beamline has a fully focused beam of 0.3 × 2.3 µm (vertical × horizontal) with a tuneable energy range (6–28 keV) and high flux (1.6 × 1012 photons s−1 at 12.5 keV). The crystals are housed within a vacuum chamber to minimize background scatter from air. Crystals are plunge-cooled on cryo-electron microscopy grids, allowing much of the liquid surrounding the crystals to be removed. These factors improve the signal-to-noise during data collection and the lifetime of the microcrystals can be prolonged by exploiting photoelectron escape. A novel in vacuo sample environment has been designed which also houses a scanning electron microscope to aid with sample visualization. This combination of features at VMXm allows measurements at the physical limits of X-ray crystallography on biomacromolecules to be explored and exploited.

Geological samples are inherently multi-scale. Understanding their bulk physical and chemical properties requires characterization down to the nano-scale. A powerful technique to study the three-dimensional microstructure is X-ray tomography, but it lacks information about the chemistry of samples. To develop a methodology for measuring the multi-scale 3D microstructure of geological samples, correlative X-ray micro- and nanotomography were performed on two rocks followed by scanning electron microscopy with energy-dispersive spectroscopy (SEM-EDS) analysis. The study was performed in five steps: (i) micro X-ray tomography was performed on rock sample cores, (ii) samples for nanotomography were prepared using laser milling, (iii) nanotomography was performed on the milled sub-samples, (iv) samples were mounted and polished for SEM analysis and (v) SEM imaging and compositional mapping was performed on micro and nanotomography samples for complimentary information. Correlative study performed on samples of serpentine and basalt revealed multiscale 3D structures involving both solid mineral phases and pore networks. Significant differences in the volume fraction of pores and mineral phases were also observed dependent on the imaging spatial resolution employed. This highlights the necessity for the application of such a multiscale approach for the characterization of complex aggregates such as rocks. Information acquired from the chemical mapping of different phases was also helpful in segmentation of phases that did not exhibit significant contrast in X-ray imaging. Adoption of the protocol used in this study can be broadly applied to 3D imaging studies being performed at the Advanced Light Source and other user facilities.

We present first hard X-ray photoelectron spectroscopy (HAXPES) results of aqueous salt solutions and dispersions of gold nanoparticles in liquid cells equipped with specially designed microfabricated thin silicon nitride membranes, with thickness in the 15–25 nm range, mounted in a high-vacuum-compatible environment. The experiments have been performed at the HAXPES endstation of the GALAXIES beamline at the SOLEIL synchrotron radiation facility. The low-stress membranes are fabricated from 100 mm silicon wafers using standard lithography techniques. Platinum alignment marks are added to the chips hosting the membranes to facilitate the positioning of the X-ray beam on the membrane by detecting the corresponding photoemission lines. Two types of liquid cells have been used, a static one built on an Omicron-type sample holder with the liquid confined in the cell container, and a circulating liquid cell, in which the liquid can flow in order to mitigate the effects due to beam damage. We demonstrate that the membranes are mechanically robust and able to withstand 1 bar pressure difference between the liquid inside the cell and vacuum, and the intense synchrotron radiation beam during data acquisition. This opens up new opportunities for spectroscopic studies of liquids.

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Singapore-based TransferTo has partnered with the Pan-African Ecobank Group in order to expand financial access and cross-border payments across the region of Africa.

Restoration of the imperiled sagebrush biome will require tools that assist resource managers in determining which restoration practices are most effective, and when and where restoration efforts will lead to the most ecosystem recovery. New research from USGS and Colorado State University provides biome-wide insights and spatially explicit tools that can inform restoration practices. 

WHEN:  Wednesday, October 28th10am PT / 1pm ET Join Now!>> SPONSORED BY:  AT&T and NortelJoin this FREE live webinar to learn how you can save energy and costs effectively across ...

Micromax forays in the race of in-house mobile launcher driven by Machine Learning and AI to enhance the user experience.

Bacteria that resist antibiotics can be passed from food animals to humans, but not enough is known to determine the public health risks posed by such transmission, says a new report by a committee of the National Research Council.

Many U.S. farmers who grow genetically engineered (GE) crops are realizing substantial economic and environmental benefits -- such as lower production costs, fewer pest problems, reduced use of pesticides, and better yields -- compared with conventional crops, says a new report from the National Research Council.

On average, Americans die sooner and experience higher rates of disease and injury than people in other high-income countries, says a new report from the National Research Council and Institute of Medicine.

An extensive study by the National Academies of Sciences, Engineering, and Medicine has found that new technologies in genetic engineering and conventional breeding are blurring the once clear distinctions between these two crop-improvement approaches.

The National Academies Committee on Genetically Engineered Crops - Past Experiences and Future Prospects authored an almost 600-page landmark report, released in May 2016. It was perhaps the most comprehensive analysis of genetically engineered crops to date.

New Report Outlines Research Agenda to Better Understand the Relationship Among Microbiomes, Indoor Environments, and Human Health

Producing more precise county-level estimates of crops and farmland cash rents will require integrating multiple data sources using model-based predictions that are more transparent and reproducible, says a new report from the National Academies of Sciences, Engineering, and Medicine.

While a variety of services and programs exist to support the needs of children with disabilities and their families, a focus on achieving specific near- and long-term goals that help prepare for adulthood and coordination of care within and across service sectors are integral to encouraging healthy growth and development, says a new report from the National Academies of Sciences, Engineering, and Medicine.

In recognition of the need for a national coordinated and collective response to the epidemic of opioid addiction in the U.S., the National Academy of Medicine (NAM), in partnership with the Aspen Institute, launched a public-private partnership made up of more than 35 organizations representing federal, state, and local governments, health systems, associations and provider groups, health education and accrediting institutions, pharmacies, payers, industry, nonprofits, and academia.

The federal government should foster collaboration and decrease obstacles that can keep foreign atomic, molecular, and optical (AMO) physicists from working in the United States, if the nation is to maintain its position as leader in these fields, says a new report from the National Academies of Sciences, Engineering, and Medicine.

There are the telltale signs of aging — a few more wrinkles, graying hair, and changes in posture. Other changes are less obvious. Aging-related changes also occur within the gut microbiome — a collection of bacteria, viruses, and fungi that live in your digestive tract.

Significantly reducing lead emissions from gasoline-powered aircraft will require the leadership and strategic guidance of the Federal Aviation Administration (FAA) and a broad-based and sustained commitment by other government agencies and the nation’s pilots, airport managers, aviation fuel and service suppliers, and aircraft manufacturers, says a new congressionally mandated report from the National Academies of Sciences, Engineering, and Medicine.

If combined with public transit and increased in scale, shared modes of transportation, such as ride-hailing, scooter sharing, and bike sharing, can enhance mobility, equity, and sustainability in metropolitan areas, according to a new report from the National Academies of Sciences, Engineering, and Medicine.

To address enduring and evolving nuclear threats, the U.S. needs a higher prioritized and more integrated program for monitoring, detecting, and verifying nuclear test explosions, nuclear weapon stockpiles, and the production of fissile material, says a new report from the National Academies of Sciences, Engineering, and Medicine.

Some of NASA’s robotic missions to Mars could be subject to less stringent bioburden requirements, which are designed to prevent the unintentional transport of Earth-based microbes, without interfering with searches for indigenous life on the planet.

Safe, effective antimicrobial medicines are essential to modern medical procedures and pandemic preparedness. A new National Academies report recommends a range of policy, regulatory, and financial actions to tackle antimicrobial resistance, spanning human, animal, and environmental health.

Among the many parts of the U.S. public health system strained by the COVID-19 pandemic were the Centers for Disease Control and Prevention’s Division of Global Migration and Quarantine and its network of quarantine stations. A recent report explored how to improve these stations based on lessons learned during the pandemic.

A new roundtable will hold its first public meeting on Jan. 23 to discuss challenges associated with incorporating climate change into the macroeconomic analyses used for federal policymaking. The roundtable’s activities will inform a new White House interagency working group.

The global community is in a crucial window for taking steps to address the numerous threats that climate change poses. Climate Crossroads is a major new initiative at the National Academies to help the nation meet the challenges of climate change.

Organizations, including those that weren’t struck by the CrowdStrike incident, should resist the temptation to attribute the IT meltdown to exceptional circumstances

ESET research examines the group's malicious wares as used to spy on targets in Ukraine in the past two years

Following the takedown of RedLine Stealer by international authorities, ESET researchers are publicly releasing their research into the infostealer’s backend modules

The widespread adoption of cellular connectivity will also contribute to a further reduction in prices for cellular-connected devices, making them more competitive against alternative non-cellular connectivity technologies like LoRa, Sigfox and Wi-SUN, Shah said.

Noam Shazeer, an AI pioneer who left Google in 2021, has returned to the company after Google paid $2.7 billion to acquire his startup, Character.AI. Shazeer is now a vice president at Google and will lead the development of their next-generation AI project, Gemini. This move highlights the intense competition for top AI talent in Silicon Valley.

It will also serve to expand the company's European operations by adding four delivery sites across Germany and the Netherlands, including a specialised Advanced Driver Assistance Systems (ADAS) and imaging centre-of-excellence lab.

The Indian government is expected to propose a penalty of up to Rs 500 crore for violations of the Digital India Bill. The bill would authorize government agencies to monitor and collect traffic data to enhance cyber security. The proposed Digital India Authority would handle grievances and determine the penalty amount based on factors such as the gravity of the breach and the number of affected users.

The European Commission in September opened investigations to assess whether Microsoft's Bing, Edge and Microsoft Advertising as well as Apple's iMessage should be subject to the Digital Markets Act (DMA).

For large enterprises, Conversational AI isn't just another digital tool; it's becoming a strategic imperative. Consider this: a typical Fortune 500 company handles over 50 million customer interactions annually across various channels – from social media and websites to mobile apps and contact centers.

The gusting westerly winds that dominate the climate in central Asia, setting the pattern of dryness and location of central Asian deserts, have blown mostly unchanged for 42 million years. A University of Washington geologist led a team that has discovered a surprising resilience to one of the world's dominant weather systems. The finding could help long-term climate forecasts, since it suggests these winds are likely to persist through radical climate shifts.

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The Series A round was led by RTP Global while YourNest and Omidyar Network India, an investment firm focused on impact, also participated, along with Global Brain, Blume Founders Fund, Alteria Capital, Stride Ventures, Stride One and 9 Unicorns.

How do you turn a problem into an opportunity? When looking for innovative ways to increase the reach and impact of an annual global event, while reducing travel costs, Andres Bulto talked to BT.

Navigate to the "Mark as important" button which is present beneath the compose box and select either the "Important" or "Urgent" option depending on the level of attention the message requires.

Oppo aims to make generative artificial intelligence accessible to 50 million users by 2024 through collaborations with Google and Microsoft, joining other handset makers like Samsung and Xiaomi in leveraging AI for sales growth.

The new offering uses a combination of existing quantum computers, artificial intelligence and conventional high-performance computing systems.