Microfluidic devices having a protein renaturation component and methods for using the same are provided. Aspects of the present disclosure include microfluidic devices that include a separation medium with a first flow path and a protein renaturation component in fluid communication with the separation medium and having a second flow path. Also provided are methods of using the devices as well as systems and kits that include the devices. The devices, systems and methods find use in a variety of different applications, including diagnostic and validation assays.

Methods and systems for selectively capturing analytes, such as cells, e.g., circulating tumor cells (CTCs), from fluid samples are disclosed. The methods include contacting the sample with an analyte binding moiety that selectively binds to the analytes; optionally separating first components of the sample including a majority of the analytes bound to the binding moieties from second components of the sample using size-based separation, e.g., in a microfluidic channel; adding to the first components of the sample a plurality of binding agents under conditions that enable a plurality of the binding agents to be linked to the analyte binding moieties to form multivalent tagging agents bound to the analyte; passing the first components of the sample past a surface to which is attached a plurality of capture agents that selectively bind to the binding agents; and capturing the analytes by providing conditions that enable the multivalent tagging agents bound to the analytes to bind to one or more of the capture agents.

The present invention provides stabilized oil-in-water emulsions with an extended range of chemical, thermal and/or mechanical stabilities, and method(s) for their preparation. Such preparations provide an environmentally-protective biopolymer component exhibiting improved adherence to the dispersed phase, reducing or eliminating dissociation therefrom under such conditions, for use in the context of a range of food, pharmaceutical, personal care, health care, cosmetic and other end-use applications.

The scroll refrigeration compressor includes a sealed casing, stationary and moving volutes including spiral wraps engaged in one another and defining the variable-volume compression chambers, a delivery chamber defined by the plate of the stationary volute and the sealed casing, a heat shield disposed in the delivery chamber and dividing the delivery chamber into a first volume defined by the plate of the stationary volute and the heat shield and a second volume defined by the heat shield and the sealed casing, and at least one flow passage arranged to communicate the first and second volumes. The compressor further includes at least one bypass passage arranged to communicate the first volume with an intermediate compression chamber, and at least one bypass valve disposed in the first volume and movable between closing and opening positions for closing and opening the corresponding bypass passage.

A compressor is provided and may include a shell, a motor assembly, a drive shaft, a first compression mechanism, and a second compression mechanism. The motor assembly may be disposed within the shell. The drive shaft may be powered by the motor assembly. The first compression mechanism may be disposed within the shell and may be driven by the motor assembly. The second compression mechanism may be driven by the motor assembly.

A microlaser system includes an optical source, a microlaser, an actuator switch, and a photovoltaic power source. The microlaser, which includes a control element, is optically pumped by at least a portion of light emitted by the optical source. The actuator switch is configured to be activated by a triggering event. Furthermore, the photovoltaic power source is coupled in a series connection with the actuator switch and the control element, the series connection configured to connect the photovoltaic power source to the control element of the microlaser when the actuator switch is activated by the triggering event.

Novel methods and systems for miniaturized lasers are described. A photonic crystal is bonded to a silicon-on-insulator wafer. The photonic crystal includes air-holes and can include a waveguide which couples the laser output to a silicon waveguide.

A device including one or more layers with lateral regions configured to facilitate the transmission of radiation through the layer and lateral regions configured to facilitate current flow through the layer is provided. The layer can comprise a short period superlattice, which includes barriers alternating with wells. In this case, the barriers can include both transparent regions, which are configured to reduce an amount of radiation that is absorbed in the layer, and higher conductive regions, which are configured to keep the voltage drop across the layer within a desired range.

Methods for the fabrication of a Microelectromechanical Systems (“MEMS”) devices are provided, as are MEMS devices. In one embodiment, the MEMS device fabrication method includes forming at least one via opening extending into a substrate wafer, depositing a body of electrically-conductive material over the substrate wafer and into the via opening to produce a via, bonding the substrate wafer to a transducer wafer having an electrically-conductive transducer layer, and forming an electrical connection between the via and the electrically-conductive transducer layer. The substrate wafer is thinned to reveal the via through a bottom surface of the substrate wafer, and a backside conductor is produced over a bottom surface of the substrate wafer electrically coupled to the via.

Embodiments of a method for fabricating stacked microelectronic packages are provided, as are embodiments of a stacked microelectronic package. In one embodiment, the method includes arranging microelectronic device panels in a panel stack. Each microelectronic device panel includes a plurality of microelectronic devices and a plurality of package edge conductors extending therefrom. Trenches are formed in the panel stack exposing the plurality of package edge conductors. An electrically-conductive material is deposited into the trenches and contacts the plurality of package edge conductors exposed therethrough. The panel stack is then separated into partially-completed stacked microelectronic packages. For at least one of the partially-completed stacked microelectronic packages, selected portions of the electrically-conductive material are removed to define a plurality of patterned sidewall conductors interconnecting the microelectronic devices included within the stacked microelectronic package.

A microelectronic assembly and method of making, which includes a first microelectronic element (including a substrate with first and second opposing surfaces, a semiconductor device, and conductive pads at the first surface which are electrically coupled to the semiconductor device) and a second microelectronic element (including a handler with first and second opposing surfaces, a second semiconductor device, and conductive pads at the handler first surface which are electrically coupled to the second semiconductor device). The first and second microelectronic elements are integrated such that the second surfaces face each other. The first microelectronic element includes conductive elements each extending from one of its conductive pads, through the substrate to the second surface. The second microelectronic element includes conductive elements each extending between the handler first and second surfaces. The conductive elements of the first microelectronics element are electrically coupled to the conductive elements of the second microelectronics element.

Disclosed are one-port and two-port voltage-tunable micro-electromechanical capacitors, switches, and filter devices. High aspect-ratio metal micromachining is used to implement very high quality factor (Q) tunable and fixed capacitors, fixed inductors, and low insertion loss tunable and fixed bandpass LC filters. The tunable capacitors can move in the plane of the substrate by the application of DC voltages and achieve greater than 100% of tuning. A combination of low-loss substrate and highest conductivity metal is used to achieve record high Q and low insertion loss at radio frequencies. The disclosed tunable capacitor structure can also be used as a micromechanical switch.

Disclosed is a coolant with dispersed neutron poison micro-particles, used in a supercritical water-cooled reactor (SCWR) emergency core cooling system. Since the neutron poison micro-particles are uniformly dispersed in the coolant of the emergency core cooling system for a long period time, their fluidity is not lowered even though the polarity of water is changed in a supercritical state. Therefore, the neutron poison micro-particles absorb neutrons produced from nuclear fission in a nuclear reactor core. Accordingly, the neutron poison micro-particles can be appropriately used as a means for controlling neutrons and stopping a nuclear reactor in the SCWR emergency core cooling system.

A negotiable instrument such as a check includes a unique microprint identifier that allows for authentication while preventing unauthorized reproduction and alternation. A printing system generates the identifier after receiving a customer order for printing a plurality of negotiable instruments, to allow inclusion of information that is specific to the customer order and/or the printing process. In various embodiments, the identifier is unique to each or each subset of the plurality of negotiable instruments and facilitates authentication of each of the negotiable instruments when needed.

A porous silica material in which silica particles are connected to one another three-dimensionally, wherein: the porous silica material includes a through hole including first pores smaller than a mean free path of an air, and second pores larger than the first pores; the porous silica material has a density of 100 kg/m3 or more and 300 kg/m3 or less; and an isobutyl group is bound to silicon of silica of the silica particles.

The invention relates to a catalytic reactor including: at least one first architecture/microstructure including a ceramic and/or metal cellular architecture having a pore size of 2 to 80 ppi and a macroporosity of more than 85%, and a microstructure having a grain size of 100 nm to 5 microns, and skeleton densification of more than 95%, and a catalytic layer; and at least one second architecture/microstructure including a spherical or cylindrical architecture having a pore size of 0.1 to 100 μm and a macroporosity of less than 60%, and a microstructure having a grain size of 20 nm to 10 μm and a skeleton densification of 20% to 90%, and a catalytic layer; the first and second architecture/microstructure being stacked inside said reactor.

System and method for sustainable economic development which includes hydrogen extracted from substances, for example, sea water, industrial waste water, agricultural waste water, sewage, and landfill waste water. The hydrogen extraction is accomplished by thermal dissociation, electrical dissociation, optical dissociation, and magnetic dissociation. The hydrogen extraction further includes operation in conjunction with energy addition from renewable resources, for example, solar, wind, moving water, geothermal, or biomass resources.

The present invention provides a surface covering for enabling a surface, e.g. of the uneven, muddy, marshy, or sandy ground type, to be crossed by a vehicle, said surface covering including a double-ply textile core having two covered faces, each covered with at least one polymer layer, and a plurality of through tubular pockets extending substantially transversely through the thickness of the core between the two layers, and enabling respective stiffener bars to be inserted into each tubular pocket so as to make it possible, in particular, to increase the drivability and the load-bearing capacity of the surface when the surface covering is positioned on said surface.

A packaging device allowing for the distribution, storage and cooking of various food products, such as perishable or frozen food product(s). The packaging device includes a plurality of micro-perforations that may promote the extended shelf-life of the perishable food product and the maintenance of the quality of the perishable food product or be configured to maintain the integrity of a frozen food product. The packaging device also includes a venting system that allows the cooking of the perishable or frozen food products within the packaging device.

The invention relates to a method for producing a bevel gear wheel, in particular for rudder propellers, the teeth of which have a macro geometry specific to the gear wheels, the teeth of which can be described by flank and profile lines, the flanks of which have a tooth flank micro topography and the bearing surface of which represents the contact region of the inter-meshing teeth. The crown of a tooth flank corresponds to the elevation of the tooth flank center with respect to the tooth flank edge, wherein the course of the height and width crowns of the flank surface is substantially shaped like a circular arc. By means of precise material removal, the micro topography of the tooth flank and thus the bearing surface is optimized firstly in that the material removal is carried out such that the end relief on the tooth flank surface is reduced toward the tooth heel side and the tooth toe side, an area having a greater length and width comes into engagement on the flank and thus an enlarged bearing surface is present, and secondly in that the course of the crown the crown of a tooth flank follows an approximately logarithmic, elliptical and/or an exponential curve shape, which runs through the point of contact, when the ease-off is viewed with no load, in a longitudinal section in the flank sectional surface and/or in a profile section in the profile sectional surface.

A case mouth chamfer tool utilizes an easily adjustable cutter holder member. The adjustable cutter holder member slides in a dovetail, is adjusted by advancing and retreating a screw, and is held in place by a set screw. The case mouth chamfer tool may be fixed to a micrometer dial threadedly engaging a barrel. A case adapter bearing is fixed to the barrel. The case mouth chamfer tool is adjusted to cut an inside chamfer and the micrometer dial is rotated to adjust the position of the case mouth chamfer tool with respect to the case adapter bearing to precisely adjust the amount of material cut from the case. The case adapter bearing is easily changed to chamfer different cases.

Wind turbine rotor blades include a shell having a leading edge opposite a trailing edge, a structural support member that supports the shell and is disposed internal the wind turbine rotor blade between the leading edge and the trailing edge and extends for at least a portion of a rotor blade span length, and a resistive cellular support structure disposed at least partially about the wind turbine rotor blade that physically supports at least a portion of the wind turbine rotor blade and at least partially absorbs radar energy.

Wind turbine rotor blades with a reduced radar cross sections include a shell having a leading edge opposite a trailing edge, a structural support member that supports the shell and is disposed internal the wind turbine rotor blade between the leading edge and the trailing edge and extends for at least a portion of a rotor blade span length, wherein the structural support member comprises fiberglass, one or more cavities internal the wind turbine rotor blade, and a lightweight broadband radar absorbing filler material disposed in at least one of the one or more cavities to provide the reduced radar cross section.

A mirror for the EUV wavelength range (1) having a layer arrangement (P) applied on a substrate (S), the layer arrangement having a periodic sequence of individual layers, where the periodic sequence has at least two individual layers—forming a period—composed respectively of silicon (Si) and ruthenium (Ru). Also disclosed are a projection objective for microlithography (2) including such a mirror, and a projection exposure apparatus for microlithography having such a projection objective (2).

In a wireless network, plural downlink signals from plural base stations are transmitted to a terminal. The plural downlink signals all carry the same information to the terminal. The terminal provides feedback on the downlink channels. The feedback provides information on the taps of the channels. The amount of information fed back is constrained. Based on the feedback, transmission parameters of the downlink signals are adjusted. The process of transmitting, providing feedback, and adjusting the parameters continue so that the energy of the downlink signal is enhanced at the terminal location and suppressed elsewhere. Beam forming can be used to further suppress the energy signature at locations other than the terminal location.

A method and device that interrogates the availability of a called party before placing a communication from the calling party to the called party. A callback may be initiated so that both communications are completed simultaneously. The routing of communication may take place through any one of a number of different networks and at another time of the day, even if the caller does not otherwise have access to those networks.

In some embodiments, a method for processing output of at least one microphone of a device (e.g., a headset) to identify at least one touch gesture exerted by a user on the device, including by distinguishing the gesture from input to the microphone other than a touch gesture intended by the user, and by distinguishing between a tap exerted by the user on the device and at least one dynamic gesture exerted by the user on the device, where the output of the at least one microphone is also indicative of ambient sound (e.g., voice utterences). Other embodiments are systems for detecting ambient sound (e.g., voice utterences) and touch gestures, each including a device including at least one microphone and a processor coupled and configured to process output of each microphone to identify at least one touch gesture exerted by a user on the device.

In one example, a method includes receiving an indication of an input gesture detected at a presence-sensitive input device, where the input gesture includes one or more input points and each input point is detected at a respective location of the presence-sensitive input device. The method may also include determining a focal point of the input gesture, and determining a radius length. The method may also include determining a shape centered at the focal point and having a size determined based on the radius length. The method may also include responding to a change in a geometric property of the shape by scaling information included in a graphical user interface, where the scaling of the information being centered at the focal point.

The present invention provides an artificial microstructure employed in an artificial electromagnetic material. The artificial microstructure includes a first segment, a second segment, and a third segment. The first segment is parallel to the second segment, and the third segment is connected between the first segment and the second segment. The artificial electromagnetic material has a special electromagnetic effect. The artificial electromagnetic material can be applied to various electromagnetic application systems instead of the typical electromagnetic material.

A method for scheduling a charge of a plug-in electric vehicle (PEV) includes receiving, by a load management system, PEV information from a PEV plugged into an electric vehicle supply equipment (EVSE); transformer information from a transformer management system, the transformer information relating to a transformer associated with the EVSE; determining, by the charging information based on the PEV information and transformer information; providing the charging information to the PEV.

A device for use during riding and training of animals such as horses which can be utilized either as a riding crop or longeing whip. The body portion of the device defines a crop having a handle formed at one end and a cracker attached to the opposite end. A plurality of flexible wand elements are nested within the body portion and are telescopically extendable from that end to which the cracker is attached. A line defining a lash is attached to the wand element whose axis coincides with that of the body portion and the cracker is fabricated in the form of a closeable pocket. The device forms a longeing whip with the lash and wand elements fully extended and when retracted the lash is retained in coiled form within the closeable pocket thus converting the device to a riding crop.

The present invention relates to riding clappers crops, in which the clapper (1) is made, at least partly, of molded material the mass of which surrounds at least the adjacent end of the crop (2) in order to provide the fixation of the two parts to each other.

An improved riding crop that allows a horseback rider to retain the crop on her hand without needing to tightly grip the crop includes a rod having opposite ends, a clapper fixed at one or both ends of the rod, a grip fixed to the rod or slidably retained on the rod, and an elastic cord extending from opposite ends of the grip and through an adjustable cord lock. Other preferred embodiments include a clapper fixed at each of the opposite ends of the rod, and a grip slidably retained on the rod between a clapper at one end of the rod and a stop located between the opposite end of the rod and the midpoint of the rod, which allow a rider to use either end of the crop for cueing the horse.

A no-till apparatus for application of herbicide and fertilizer, soil preparation, and seeding of a cover crop in a standing crop has inter-row assemblies configured to pass along inter-row areas between adjacent row lines of standing crop plants. Each assembly includes a fertilizer applicator, a no-till soil preparation element, a cover crop seed applicator, and a post-seeding element.

This technology is a method and apparatus for the semi-continuous measurement of the concentration of constituents of airborne particles which couples a laminar flow, water condensation particle collector to a microfluidic device for assay of particle chemical composition by electrophoresis. The technology has been used for the assay of sulfates, nitrates, chlorides, and organic acids contained in fine and submicrometer atmospheric particles. For these compounds the apparatus and method described is capable of one-minute time resolution at concentrations at the level of micrograms of analyte species per cubic meter of air. Extension to other analytes is possible.

A microfluidic cell for the dielectrophoretic separation, accumulation, and/or lysis of polarizable bioparticles, including an interdigital electrode system composed of two electrode groups having interdigitated electrodes, and a micromixer having microchannels and microelevations. The interdigital electrode system and the micromixer are situated on the same side of the cell to improve the separation, accumulation, and/or lysis characteristics. Moreover, also described is a microfluidic system which includes such a microfluidic cell, and use thereof, and a method for separating, accumulating, and/or lysing polarizable bioparticles.

A microelectronic assembly includes a first component with first conductive elements; a second component with second conductive elements; a bond metal; and an underfill layer. The posts have a height above the respective surface from which the posts project. A bond metal can be disposed between respective pairs of conductive elements, each pair including at least one of the posts and at least one of the first or second conductive elements confronting the at least one post. The bond metal can contact edges of the posts along at least one half the height of the posts. An underfill layer contacts and bonds the first and second surfaces of the first and second components. A residue of the underfill layer may be present at at least one interfacial surfaces between at least some of the posts and the bond metal or may be present within the bond metal.

Hemispheres and spheres are formed and employed for a plurality of applications. Hemispheres are employed to form a substrate having an upper surface and a lower surface. The upper surface includes peaks of pillars which have a base attached to the lower surface. The peaks have a density defined at the upper surface by an array of hemispherical metal structures that act as a mask during an etch to remove substrate material down to the lower surface during formation of the pillars. The pillars are dense and uniform and include a microscale average diameter. The spheres are formed as independent metal spheres or nanoparticles for other applications.

A three-phase disconnect switch for a power distribution system that supplies three-phase power from a source through a main circuit breaker to multiple three-phase feeder circuits, includes three pairs of contacts adapted for connection to the three phase lines of a selected one of the feeder circuits for opening and closing each of the phase lines, and a movable actuator associated with the three pairs of contacts and responsive to a signal indicating the occurrence of an arcing fault in the selected feeder circuit for initially creating a short circuit across the three phase lines of the feeder circuit and then opening the contacts.

A multi-standard flash-memory-card carrier is about the same size as a thick credit card and fits into a wallet. The multi-standard flash-memory-card carrier has bays that accept flash-memory cards. Larger bays on one side receive SD cards and a Memory Stick Duo card, while micro bays on another side of the carrier receive microSD cards and Memory Stick Micro cards. A carrier spine sandwiched between top and bottom covers has openings forming the bays. Spring-clip tabs on spring-clip fingers fit into notches on the side of the flash-memory cards to secure the flash-memory cards into the multi-standard flash-memory-card carrier to prevent loss. The spring-clip fingers are movable parts of the carrier spine that are deformed during insertion of the flash-memory cards. Both micro and standard flash-memory cards can be carried in the same multi-standard flash-memory-card carrier that can be placed in plastic sleeves for credit cards in a person's wallet.

A microwave semiconductor amplifier includes a semiconductor amplifier element, an input matching circuit and an output matching circuit. The semiconductor amplifying element includes an input electrode and an output electrode and has a capacitive output impedance. The input matching circuit is connected to the input electrode. The output matching circuit includes a bonding wire and a first transmission line. The bonding wire includes first and second end portions. The first end portion is connected to the output electrode. The second end portion is connected to one end portion of the first transmission line. A fundamental impedance and a second harmonic impedance seen toward the external load change toward the one end portion. The second harmonic impedance at the one end portion has an inductive reactance. The output matching circuit matches the capacitive output impedance of the semiconductor amplifying element to the fundamental impedance of the external load.

High impedance, high frequency nanoscale device electronics configured to interface with low impedance loads include an impedance transforming stage constructed of multiple nanoscale devices, such as carbon nanotube field-effect transistors. In an embodiment of the present invention, an impedance transforming output stage of a multistage amplifier is configured to drive a 50 ohm transmission line with unity voltage gain using multiple carbon nanotube field-effect transistors in parallel. In a further embodiment, a receiver provided for an electronically steered receive array is a monolithic, lumped-element system formed from nanoscale devices and configured to interface with the external electrical systems via a single transmission line.

In a process for producing a microneedle (12) that can be inserted into body tissue in which a needle tip (20) and a preferably capillary collecting channel (14) having a distal inlet for body fluid formed at the needle tip (20) are formed, it is provided that at least part of a preform (38) prefabricated from a flat material is shaped into a tubular structure (22) so that the collecting channel (14) is at least substantially annularly closed in the cross-section in the area of the tubular structure (22).

An arrangement for providing a throttle cross-section for a fluid flow. The throttle cross-section can be varied depending on a pressure difference present across the throttle cross-section. The arrangement is designed such that the polarity of the pressure difference, by which the throttle cross-section can be varied and/or changed. It is thereby possible to use the arrangement for fluid flows that alternate in the flow direction thereof.

A method and a system for supplying power to a microcontroller with a single cell. One embodiment of the present invention discloses incorporation of a power supply pump circuit with the microcontroller and their dynamic interaction. The microcontroller sends its power requirements to the power supply pump circuit and in response, the power supply pump circuit controls the operating voltage with optimal efficiency. The dynamic update of power supply pump circuit results in an efficient use of the power supply pump circuit and thus results in a reduction of the number of dry cell batteries to only a single cell. Incorporation of the microcontroller and power supply pump circuit onto a single chip reduces the pin number requirements as well as the space required on the printed circuit board.

A bridge for crossing a passage of a navigation channel includes a section in the form of a single span, which may be displaced by vertical translation between a base position spanning the passage, in which the span rests on fixed support sections of the bridge, and a raised position, for opening the passage, and a support structure for the span on displacement of the span, and a drive for lifting the span. The bridge has only one support structure, with the drive, located on one side of the passage to be spanned.

This disclosure relates to a micro manipulator having a simple structure and having high possibility of recording a biological signal of a neuron at a desired position by improving positioning resolution of an electrode disposed adjacent to a subject's brain neuron or an electrode holder attached with the electrode. The micro manipulator according to the disclosure includes: a motor which includes a shaft and a vibration portion; a mobile which is connected to the shaft so as to be movable along the shaft; and a frame which supports the motor, wherein an electrode is connected to the mobile in a direction parallel to a longitudinal direction of the shaft, and wherein when the mobile moves linearly in accordance with a vibration of the shaft due to the vibration portion, the electrode moves linearly.

A method and a system for supplying power to a microcontroller with a single cell. One embodiment of the present invention discloses incorporation of a power supply pump circuit with the microcontroller and their dynamic interaction. The microcontroller sends its power requirements to the power supply pump circuit and in response, the power supply pump circuit controls the operating voltage with optimal efficiency. The dynamic update of power supply pump circuit results in an efficient use of the power supply pump circuit and thus results in a reduction of the number of dry cell batteries to only a single cell. Incorporation of the microcontroller and power supply pump circuit onto a single chip reduces the pin number requirements as well as the space required on the printed circuit board.

A vehicle bumper for use with police and other emergency vehicles for pushing another vehicle which is fabricated of a tubular loop defining a generally oval cross-section. The oval cross-section tubular loop is oriented such that the major axis of the oval cross-section extends front to back with respect to the host vehicle while the minor axis extends up and down. The vehicle bumper further supports a plurality of resilient pads to aid in controlling the pushed vehicle and to cushion impact transfer between the bumper and the pushed vehicle. The inventive vehicle bumper is substantially stronger and substantially lighter in weight while simultaneously providing a more attractive front view cross-section when mounted on a host vehicle. A plurality of attachments are secured to the tubular loop and are used in securing the vehicle bumper to a suitable portion of a host vehicle.

An apparatus for treating a flow of fluid with microwave radiation, the apparatus comprising: a vessel having a sidewall and opposed first and second end walls defining a substantially cylindrical chamber, the first end wall being disposed a predetermined distance d1 from the second end wall; a pipeline for flowing fluid through, the pipeline passing through the first end wall towards the second end wall of the vessel, the chamber and the pipeline being substantially co-axial and the pipeline being substantially transparent to microwave radiation; and a microwave radiation inlet in the side wall of the vessel for admitting microwave radiation of wavelength λ into the chamber, wherein the distance d1 is substantially equal to an integral multiple of λ/2 so that the chamber is a microwave resonator.