ual [ASAP] Molecular Basis for Omapatrilat and Sampatrilat Binding to Neprilysin—Implications for Dual Inhibitor Design with Angiotensin-Converting Enzyme By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.0c00441 Full Article
ual [ASAP] Pharmacophore-Based Virtual Screening for Identification of Negative Modulators of GLI1 as Potential Anticancer Agents By feedproxy.google.com Published On :: Wed, 08 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00639 Full Article
ual [ASAP] New Dual CK2/HDAC1 Inhibitors with Nanomolar Inhibitory Activity against Both Enzymes By feedproxy.google.com Published On :: Fri, 10 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.9b00561 Full Article
ual [ASAP] Discovery of a Potent Dual Inhibitor of Wild-Type and Mutant Respiratory Syncytial Virus Fusion Proteins By feedproxy.google.com Published On :: Wed, 15 Apr 2020 04:00:00 GMT ACS Medicinal Chemistry LettersDOI: 10.1021/acsmedchemlett.0c00008 Full Article
ual Contextual styling with custom properties By simurai.com Published On :: Sun, 01 Apr 2018 00:00:00 +0000 Something I’ve been wanting for a long time, define different regions like a footer section, or side bar and not have to deal with all the contextual styling hassle. A.k.a. “Now that this button is used on a dark background, the button needs to change its colors too. Where should the styles live?”. Here an old post about struggling with contextual styling. So then the other day I was doing some experiments with using custom properties for Atom’s UI. Turns out, using custom properties might make contextual styling a bit easier. For the rest of the post, let’s switch to a more simple example. A page where the main area is light, but then has a dark hero and footer section. Like this: In the past, I probably would’ve created variations like Button--dark or overwrote it with header .Button {…}. Depends a bit on the project. Here another approach: Create themes with a set of variables, then apply the theme to the different areas. 1. Default theme First let’s define our default theme with a bunch of variables. [data-theme="default"] { --fg: hsl(0,0%,25%); --border: hsl(0,0%,75%); --bg: hsl(0,0%,95%); --button-bg: hsl(0,0%,99%); --input-bg: hsl(0,0%,90%); } Then we create some components where we use the variables defined above. [data-theme] { color: var(--fg); background-color: var(--bg); } .Button { color: var(--fg); border: 1px solid var(--border); background-color: var(--button-bg); } .Input { color: var(--fg); border: 1px solid var(--border); background-color: var(--input-bg); } And lastly we add the [data-theme="default"] attribute on the body so that our components will pick up the variables. <body data-theme="default"> If you wonder why use data-theme attributes over classes? Well, no specific reason. Maybe with attributes, it’s a hint that only one theme should be used per element and is more separated from your other classes. At this point we get this: See the Pen Contextual styling with custom properties (1/3) by simurai (@simurai) on CodePen. 2. Dark theme But our designer wants the hero and footer to be dark. Alright, let’s define another theme region. [data-theme="dark"] { --fg: hsl(0,10%,70%); --border: hsl(0,10%,10%); --bg: hsl(0,0%,20%); --button-bg: hsl(0,0%,25%); --input-bg: hsl(0,0%,15%); } And add the theme attribute to the header and footer. <header data-theme="dark"> <footer data-theme="dark"> Which gives us this: See the Pen Contextual styling with custom properties (2/3) by simurai (@simurai) on CodePen. The reason why this works is that custom properties cascade and can be overridden on nested elements, just like normal properties. 3. Hero theme A few months pass and our designer comes back with a redesigned hero section. “To make it look fresh” with a splash of color. No problem! Just like with the dark theme, we define a new “hero” theme. [data-theme="hero"] { --fg: hsl(240,50%,90%); --border: hsl(240,50%,10%); --bg: hsl(240,33%,30%); --button-bg: hsl(240,33%,40%); --input-bg: hsl(240,33%,20%); } <header data-theme="hero"> And here is that fresh hero: See the Pen Contextual styling with custom properties (3/3) by simurai (@simurai) on CodePen. It’s also not limited to colors only, could be used for sizes, fonts or anything that makes sense to define as variables. Benefits Using these theme “regions” lets your components stay context un-aware and you can use them in multiple themes. Even on the same page. Developers can add components, move components around, without having to know about in what context (theme) they live. The markup for the components stays the same. Design systems authors can create new components without worrying about where they get used, the variables used in components stay the same. Designers can define new theme regions, or change existing ones, without having to make changes to a component’s HTML or CSS, it stays the same. Less time to talk about who, how and where, more time to talk about the weather. ☔️???? Concerns Yeah, right. The big question: But does it scale? Can this be used for all use cases. Ok, I’m pretty sure it doesn’t fit all situations. There are just too many to find a single solution for them all. And I’m actually not sure how well it scales. I guess it works great in these simple demos, but I have yet to find a larger project to test it on. So if you have used (or plan to use) this approach, I’m curious to know how it went. A concern I can imagine is that the list of variables might grow quickly if themes have totally different characteristics. Like not just a bit darker or lighter backgrounds. Then you might need to have foreground and border colors for each component (or group of components) and can’t just use the general --fg and --border variables. Naming these variables is probably the hardest part. Update I @giuseppegurgone made an interesting comment: in suitcss projects I used to define component level custom props, theme variables and then create themes by mapping the former to the latter suitcss-toolkit So if I understood it correctly, by mapping theme variables to component variables, you could avoid your theme variables from growing too much and you can decide for each component how to use these theme variables. Update II If it’s too early to use custom properties in your project, @szalonna posted an example how to do something similar in SCSS. Full Article
ual Land, sand, strand: activation manual / drawings by Suki Seokyeong Kang By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N6488.I8 V433 2019 K6 Full Article
ual Exercises in freedom: polnische Konzeptkunst, 1968-1981 = Polish conceptualism, 1968-1981 / Herausgeber = editor, Staatliche Kunstsammlungen Dresden, Kupferstich-Kabinett, Björn Egging By library.mit.edu Published On :: Sun, 23 Feb 2020 06:00:02 EST Rotch Library - N7255.P6 E88 2018 Full Article
ual Introducing science through images: cases of visual popularization / Maria E. Gigante By library.mit.edu Published On :: Sun, 26 Apr 2020 06:00:01 EDT Rotch Library - N72.S3 G54 2018 Full Article
ual Crítica textual: un enfoque multidisciplinario para la edición de textos / editores, Belem Clark de Lara [and others] By library.mit.edu Published On :: Sun, 25 Nov 2018 06:36:04 EST Online Resource Full Article
ual Lírica cortesana y lírica popular actual / Yvette Jiménez de Baez By library.mit.edu Published On :: Sun, 24 Feb 2019 09:28:49 EST Online Resource Full Article
ual Creating a Gender-Equal and Equitable World By www.mathematica.org Published On :: Fri, 06 Mar 2020 18:25:24 Z At Mathematica, we work collectively with partners across the country and around the globe to create a gender-equal world where women, girls, communities, and economies can thrive. Full Article
ual Evaluation of multilingual and multi-modal information retrieval [electronic resource] : 7th Workshop of the Cross-Language Evaluation Forum, CLEF 2006, Alicante, Spain, September 20-22, 2006 : revised selected papers / Carol Peters [and others] (eds.) By darius.uleth.ca Published On :: Berlin ; New York : Springer, 2007 Full Article
ual NATO, civilisation and individuals: the unconscious dimension of international security / Sarah da Mota By library.mit.edu Published On :: Sun, 14 Jul 2019 09:32:17 EDT Online Resource Full Article
ual La carrera de relaciones internacionales en México: orígenes y situación actual / Luis Ochoa Bilbao By library.mit.edu Published On :: Sun, 4 Aug 2019 10:22:43 EDT Online Resource Full Article
ual Abuses of the erotic: militarizing sexuality in the post-Cold War United States / Josh Cerretti By library.mit.edu Published On :: Sun, 26 Apr 2020 09:04:30 EDT Dewey Library - JZ6405.W66 C47 2019 Full Article
ual The guarantee of perpetual peace / Wolfgang Ertl By library.mit.edu Published On :: Sun, 3 May 2020 10:24:48 EDT Online Resource Full Article
ual Pensar el fenómeno narco: el narcotráfico en los discursos audiovisuales (2010-2015) / Esteban Mizrahi [and 6 others] By library.mit.edu Published On :: Sun, 15 Sep 2019 07:36:30 EDT Online Resource Full Article
ual Science fiction cinema and 1950s Britain: recontextualising cultural anxiety / Matthew Jones By library.mit.edu Published On :: Sun, 3 Nov 2019 06:37:50 EST Online Resource Full Article
ual Queer timing: the emergence of lesbian sexuality in early cinema / Susan Potter By library.mit.edu Published On :: Sun, 23 Feb 2020 07:00:06 EST Hayden Library - PN1995.9.L48 P68 2019 Full Article
ual Stanley Kubrick: New York Jewish intellectual / Nathan Abrams By library.mit.edu Published On :: Sun, 26 Apr 2020 07:06:33 EDT Hayden Library - PN1998.3.K83 A57 2018 Full Article
ual Affectual erasure: representations of indigenous peoples in Argentine cinema / Cynthia Margarita Tompkins By library.mit.edu Published On :: Sun, 26 Apr 2020 07:06:33 EDT Hayden Library - PN1995.9.I49 T66 2018 Full Article
ual Intimate visualities and the politics of fandom in India / Roos Gerritsen By library.mit.edu Published On :: Sun, 3 May 2020 07:23:24 EDT Dewey Library - PN1993.5.I8 G47 2019 Full Article
ual Child Care and Early Education Policy Research Consortium Annual Meeting By www.mathematica.org Published On :: Wed, 07 Feb 2018 05:00:00 Z The Child Care and Early Education Policy Research Consortium (CCEEPRC) provided a forum for researchers and policymakers to investigate emerging research findings, questions, and methods that relate to improved outcomes for children and families. Several Mathematica researchers presented on topics such as: child care quality measures, support for home-based care providers, and research on coordinated services for children and their families. Full Article
ual Disability Research Consortium Annual Meeting 2018 By www.mathematica.org Published On :: Wed, 01 Aug 2018 12:00:00 Z This conference highlighted the DRC’s latest research findings and their implications for the future of state and federal disability policies and programs. Full Article
ual Seeing Is Believing: Visualizing Data for Evidence-Based Policymaking By www.mathematica.org Published On :: Tue, 01 Oct 2019 19:00:00 Z While many industries have increasingly turned to data science to make informed business decisions, social service organizations and government agencies have been slower to fully embrace the potential of current and emerging data science methods. The challenges are real. Full Article
ual Q-CCIIT: Measuring the Quality of Caregiver–Child Interactions: Free Webinar for Early Childhood Professionals By www.mathematica.org Published On :: Tue, 17 Mar 2020 17:00:00 Z Mathematica will launch a groundbreaking new quality measurement observation tool, now available to the early childhood community (including program administrators, professional development providers, researchers, and others) during a webinar. Full Article
ual Simultaneous co-assembly of fenofibrate and ketoprofen peptide for the dual-targeted treatment of nonalcoholic fatty liver disease (NAFLD) By feeds.rsc.org Published On :: Chem. Commun., 2020, 56,4922-4925DOI: 10.1039/D0CC00513D, CommunicationZhongyan Wang, Chuanrui Ma, Yuna Shang, Lijun Yang, Jing Zhang, Cuihong Yang, Chunhua Ren, Jinjian Liu, Guanwei Fan, Jianfeng LiuAn ingenious co-assembled nanosystem based on fenofibrate and ketoprofen peptide for the dual-targeted treatment of NAFLD by reducing hepatic lipid accumulation and inflammatory responses.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual A dual-round signal amplification strategy for colorimetric/photoacoustic/fluorescence triple read-out detection of prostate specific antigen By feeds.rsc.org Published On :: Chem. Commun., 2020, 56,4942-4945DOI: 10.1039/D0CC01086C, CommunicationChao Jiang, Yan Huang, Ting He, Peng Huang, Jing LinA colorimetric/fluorescence/photoacoustic triple read-out detection of prostate specific antigen (PSA) was developed by using a silica coated Au@Ag core–shell nanorod (denoted Au@Ag@SiO2) based enzyme-linked immunosorbent assay (ELISA) system.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual A DNA logic gate with dual-anchored proximity aptamers for accurate identification of circulating tumor cells By feeds.rsc.org Published On :: Chem. Commun., 2020, Accepted ManuscriptDOI: 10.1039/D0CC00564A, CommunicationTianshu Chen, Xin Fu, Qianqian Zhang, Dongsheng Mao, Yuchen Song, Chang Feng, Xiaoli ZhuWe have designed a DNA logic gate that can integrate multiple biomarkers recognition with signal amplification to perform accurate and and sensitive analysis of circulating tumor cells (CTCs). It also...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual Deep imaging for visualizing nitric oxide in lipid droplets: discovering the relationship between nitric oxide and resistance to cancer chemotherapy drugs By feeds.rsc.org Published On :: Chem. Commun., 2020, Advance ArticleDOI: 10.1039/D0CC01856B, CommunicationMiantai Ye, Wei Hu, Meng He, Chenchen Li, Shuyang Zhai, Zhihong Liu, Yanying Wang, Huijuan Zhang, Chunya LiA near-infrared two-photon fluorescent probe for selective detection and deep-depth imaging of NO helps to discover the relationship between NO and resistance to antitumor drugs.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual Enzyme-mimicking accelerated signal enhancement for visually multiplexed quantitation of telomerase activity By feeds.rsc.org Published On :: Chem. Commun., 2020, Accepted ManuscriptDOI: 10.1039/D0CC01951H, CommunicationLu Sun, Qiao Zhao, Xinli Liu, Yongchun Pan, Yanfeng Gao, Jingjing Yang, Yuzhen Wang, Yujun SongHere, we propose an amplification strategy of enzyme-mimicking accelerated signal enhancement integrated with triple-channel volumetric bar-chart chip for visually multiplexed quantitation of telomerase activity. This platform was used for evaluating...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual A combined viscosity-restricted intramolecular motion and mitochondrial targeting leads to selective tumor visualization By feeds.rsc.org Published On :: Chem. Commun., 2020, Accepted ManuscriptDOI: 10.1039/D0CC02943B, CommunicationLe Yu, Jun Feng Zhang, Mingle Li, Dewei Jiang, Ying Zhou, Peter Verwilst, Jong Seung KimWe report a novel fluorescent molecular conjugate V-M1 enabling an accurate visualization of tumor tissues. The emission wavelength of V-M1 exceeds 650 nm, well within the near-infrared therapeutic window. Tumor...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
ual Oracle programming with Visual Basic / Nick Snowdon By prospero.murdoch.edu.au Published On :: Snowdon, Nick Full Article
ual Researching virtual worlds : methodologies for studying emergent practices / edited by Ursula Plesner and Louise Phillips By prospero.murdoch.edu.au Published On :: Full Article
ual Virtual world design / Ann Latham Cudworth By prospero.murdoch.edu.au Published On :: Cudworth, Ann Latham, 1955- Full Article
ual The Oxford handbook of virtuality / edited by Mark Grimshaw By prospero.murdoch.edu.au Published On :: Full Article
ual Grid systems in graphic design : a visual communication manual for graphic designers, typographers and three dimensional designers = Raster Systeme für die visuelle Gestaltung: ein Handbuch für Grafiker, Typografen und Ausstellungsgestalter / Jo By prospero.murdoch.edu.au Published On :: Müller-Brockmann, Josef, 1914-1996, author Full Article
ual Visual research : an introduction to research methodologies in graphic design / Ian Noble, Russell Bestley ; foreward by Ellen Lupton By prospero.murdoch.edu.au Published On :: Noble, Ian, 1960- Full Article
ual A designer's research manual : succeed in design by knowing your clients and what they really need / Jenn + Ken Visocky O'Grady By prospero.murdoch.edu.au Published On :: Visocky O'Grady, Jennifer Full Article
ual Geometric graphics : a visual celebration of simple forms / [chief editor, Wang Shaoqiang] By prospero.murdoch.edu.au Published On :: Full Article
ual 2800 QCM de culture générale et d'actualité - Méthode et entraînement - Catégories B et C By www.vuibert.fr Published On :: Wed, 29 Apr 2020 04:01:37 +0000 13,99 €19,90 € Mélanie Hoffert, Lionel Lavergne 7e édition mars 2020 352 pages Un entraînement intensif en culture générale et actualité pour réussir les épreuves écrites et orales des concours de catégories B et C ! Ouvrage d'entraînement Nouveau 978-2-311-20842-9 Concours 2020-2021 Disponible Livre Full Article
ual Platonic architectonics : Platonic philosophies & the visual arts / John Hendrix By prospero.murdoch.edu.au Published On :: Hendrix, John Shannon Full Article
ual The inheritance of wealth : justice, equality, and the right to bequeath / Daniel Halliday By prospero.murdoch.edu.au Published On :: Halliday, Daniel, author Full Article
ual Body-self dualism in contemporary ethics and politics / Patrick Lee (Franciscan University of Steubenville), Robert P. George (Princeton University) By prospero.murdoch.edu.au Published On :: Lee, Patrick, 1952- author Full Article
ual Philosophy of mind and phenomenology [electronic resource] : conceptual and empirical approaches / edited by Daniel O. Dahlstrom, Andreas Elpidorou, and Walter Hopp By prospero.murdoch.edu.au Published On :: Full Article
ual Dazzling darkness : gender, sexuality, illness and God / Rachel Mann By prospero.murdoch.edu.au Published On :: Mann, Rachel, author Full Article
ual Intimate assemblages: the politics of queer identities and sexualities in Indonesia / Hendri Yulius Wijaya By library.mit.edu Published On :: Sun, 15 Mar 2020 08:09:28 EDT Online Resource Full Article
ual The Great Leveler: Violence and the History of Inequality from the Stone Age to the Twenty-First Century. By library.mit.edu Published On :: Sun, 22 Mar 2020 07:44:49 EDT Online Resource Full Article
ual King and the other America: the Poor People's Campaign and the quest for economic equality / Sylvie Laurent ; foreword by William Julius Wilson By library.mit.edu Published On :: Sun, 26 Apr 2020 09:04:30 EDT Dewey Library - HN90.S6 L35 2018 Full Article
ual A global history of sexual science, 1880-1960 / edited by Veronika Fuechtner, Douglas E. Haynes, and Ryan M. Jones By library.mit.edu Published On :: Sun, 26 Apr 2020 09:04:30 EDT Hayden Library - HQ60.G56 2018 Full Article
