protein [ASAP] Harnessing ß-Lactam Antibiotics for Illumination of the Activity of Penicillin-Binding Proteins in <italic toggle="yes">Bacillus subtilis</italic> By feedproxy.google.com Published On :: Fri, 20 Mar 2020 04:00:00 GMT ACS Chemical BiologyDOI: 10.1021/acschembio.9b00977 Full Article
protein [ASAP] Antibody–PROTAC Conjugates Enable HER2-Dependent Targeted Protein Degradation of BRD4 By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT ACS Chemical BiologyDOI: 10.1021/acschembio.0c00285 Full Article
protein [ASAP] Generation of Recombinant Mammalian Selenoproteins through Genetic Code Expansion with Photocaged Selenocysteine By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Chemical BiologyDOI: 10.1021/acschembio.0c00147 Full Article
protein [ASAP] Fr-PPIChem: An Academic Compound Library Dedicated to Protein–Protein Interactions By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT ACS Chemical BiologyDOI: 10.1021/acschembio.0c00179 Full Article
protein [ASAP] Site-Selective Protein Chemical Modification of Exposed Tyrosine Residues Using Tyrosine Click Reaction By feedproxy.google.com Published On :: Mon, 13 Apr 2020 04:00:00 GMT Bioconjugate ChemistryDOI: 10.1021/acs.bioconjchem.0c00120 Full Article
protein [ASAP] Artificial Molecular Chaperone Systems for Proteins, Nucleic Acids, and Synthetic Molecules By feedproxy.google.com Published On :: Sun, 26 Apr 2020 04:00:00 GMT Bioconjugate ChemistryDOI: 10.1021/acs.bioconjchem.0c00133 Full Article
protein [ASAP] Pyrocinchonimides Conjugate to Amine Groups on Proteins via Imide Transfer By feedproxy.google.com Published On :: Thu, 30 Apr 2020 04:00:00 GMT Bioconjugate ChemistryDOI: 10.1021/acs.bioconjchem.0c00143 Full Article
protein [ASAP] Supramolecular Encapsulation of Small-Ultrared Fluorescent Proteins in Virus-Like Nanoparticles for Noninvasive In Vivo Imaging Agents By feedproxy.google.com Published On :: Thu, 07 May 2020 04:00:00 GMT Bioconjugate ChemistryDOI: 10.1021/acs.bioconjchem.0c00190 Full Article
protein [ASAP] The Protein Corona Does Not Influence Receptor-Mediated Targeting of Virus-like Particles By feedproxy.google.com Published On :: Fri, 08 May 2020 04:00:00 GMT Bioconjugate ChemistryDOI: 10.1021/acs.bioconjchem.0c00240 Full Article
protein [ASAP] Mass Spectrometry-Based Protein Footprinting for Higher-Order Structure Analysis: Fundamentals and Applications By feedproxy.google.com Published On :: Wed, 22 Apr 2020 04:00:00 GMT Chemical ReviewsDOI: 10.1021/acs.chemrev.9b00815 Full Article
protein Intrinsically disordered proteins [electronic journal]. By encore.st-andrews.ac.uk Published On :: Full Article
protein Heat Shock Proteins in Signaling Pathways By library.mit.edu Published On :: Sun, 18 Aug 2019 09:32:39 EDT Online Resource Full Article
protein Biophysics of RNA-protein interactions: a mechanistic view / Chirlmin Joo, David Rueda, editors By library.mit.edu Published On :: Sun, 13 Oct 2019 07:39:15 EDT Online Resource Full Article
protein Advances in membrane proteins: building, signaling and malfunction / Yu Cao, editor By library.mit.edu Published On :: Sun, 27 Oct 2019 07:30:14 EDT Online Resource Full Article
protein Heat shock protein 60 in human diseases and disorders / Alexzander A. A. Asea, Punit Kaur, editors By library.mit.edu Published On :: Sun, 17 Nov 2019 07:51:28 EST Online Resource Full Article
protein Heat shock proteins in neuroscience / edited by Alexzander A. A. Asea, Punit Kaur By library.mit.edu Published On :: Sun, 17 Nov 2019 07:51:28 EST Online Resource Full Article
protein Protein homeostasis: a subject collection from Cold Spring Harbor perspectives in biology / edited by Richard I. Morimoto, Northwestern University, F. Ulrich Hartl, Max Planck Institute of Biochemistry, Jeffery W. Kelly, The Scripps Research Institute By library.mit.edu Published On :: Sun, 17 Nov 2019 07:51:28 EST Hayden Library - QP551.P69594 2019 Full Article
protein Heat shock protein 90 in human diseases and disorders Alexzander A.A. Asea, Punit Kaur, editors By library.mit.edu Published On :: Sun, 22 Dec 2019 07:46:07 EST Online Resource Full Article
protein Protein allostery in drug discovery / Jian Zhang, Ruth Nussinov, editors By library.mit.edu Published On :: Sun, 22 Dec 2019 07:46:07 EST Online Resource Full Article
protein Reverse phase protein arrays: from technical and analytical fundamentals to applications / Tesshi Yamada, Satoshi S. Nishizuka, Gordon B. Mills, Lance A. Liotta, editors By library.mit.edu Published On :: Sun, 19 Jan 2020 07:42:04 EST Online Resource Full Article
protein Cullin-RING ligases and protein neddylation: biology and therapeutics / Yi Sun, Wenyi Wei, Jianping Jin, editors By library.mit.edu Published On :: Sun, 16 Feb 2020 07:32:02 EST Online Resource Full Article
protein Macromolecular protein complexes II: structure and function / J. Robin Harris, Jon Marles-Wright, editors By library.mit.edu Published On :: Sun, 23 Feb 2020 09:06:07 EST Online Resource Full Article
protein Protein reviews. M. Zouhair Atassi, editor By library.mit.edu Published On :: Sun, 15 Mar 2020 07:45:28 EDT Online Resource Full Article
protein Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and Other Body Fluid Proteins By library.mit.edu Published On :: Sun, 12 Apr 2020 09:09:06 EDT Online Resource Full Article
protein Protein tyrosine phosphatases: structure, signaling and drug discovery / Lalima G. Ahuja By library.mit.edu Published On :: Sun, 26 Apr 2020 08:31:05 EDT Hayden Library - QP609.P56 A38 2018 Full Article
protein New bioprocessing strategies: development and manufacturing of recombinant antibodies and proteins / Bob Kiss, Uwe Gottschalk, Michael Pohlscheidt, editors ; with contributions by E. Abraham [and more] By library.mit.edu Published On :: Sun, 20 Jan 2019 07:42:06 EST Online Resource Full Article
protein Nanoparticle-protein corona: biophysics to biology / edited by Ashutosh Kumar and Alok Dhawan By library.mit.edu Published On :: Sun, 18 Aug 2019 06:49:38 EDT Online Resource Full Article
protein A highly stable RNA aptamer probe for the retinoblastoma protein in live cells By feeds.rsc.org Published On :: Chem. Sci., 2020, 11,4467-4474DOI: 10.1039/D0SC01613F, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Thao T. Le, Andreas Bruckbauer, Bogachan Tahirbegi, Alastair J. Magness, Liming Ying, Andrew D. Ellington, Anthony E. G. CassAn RNA G-quadruplex aptamer, specific for the human retinoblastoma protein (RB) and highly stable inside cells, is selected and its application to live cell probing of the protein illustrated.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Determination of protein-ligand binding modes using fast multi-dimensional NMR with hyperpolarization By feeds.rsc.org Published On :: Chem. Sci., 2020, Accepted ManuscriptDOI: 10.1039/D0SC00266F, Edge Article Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Yunyi Wang, Jihyun Kim, Christian HiltyElucidation of small molecule-protein interactions provides essential information for understanding biological processes such as cellular signaling, as well as for rational drug development. Here, multi-dimensional NMR with sensitivity enhancement by...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein [ASAP] Combining Docking Pose Rank and Structure with Deep Learning Improves Protein–Ligand Binding Mode Prediction over a Baseline Docking Approach By feedproxy.google.com Published On :: Tue, 03 Mar 2020 05:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.9b00927 Full Article
protein [ASAP] Will Cryo-Electron Microscopy Shift the Current Paradigm in Protein Structure Prediction? By feedproxy.google.com Published On :: Wed, 18 Mar 2020 04:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.0c00177 Full Article
protein [ASAP] Retrospect and Prospect of Single Particle Cryo-Electron Microscopy: The Class of Integral Membrane Proteins as an Example By feedproxy.google.com Published On :: Fri, 20 Mar 2020 04:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.9b01015 Full Article
protein [ASAP] Development and Evaluation of MM/GBSA Based on a Variable Dielectric GB Model for Predicting Protein–Ligand Binding Affinities By feedproxy.google.com Published On :: Fri, 20 Mar 2020 04:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.0c00024 Full Article
protein [ASAP] Deep Dive into Machine Learning Models for Protein Engineering By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.0c00073 Full Article
protein [ASAP] Accelerated Protein Folding Using Greedy-Proximal A* By feedproxy.google.com Published On :: Tue, 05 May 2020 04:00:00 GMT Journal of Chemical Information and ModelingDOI: 10.1021/acs.jcim.9b01194 Full Article
protein Variable protein expression in marine-derived filamentous fungus Penicillium chrysogenum in response to varying copper concentrations and salinity By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/C9MT00316A, PaperNikita Lotlikar, Samir Damare, Ram Murti Meena, Saranya JayachandranCopper is one of the essential trace dietary minerals for all living organisms, but is potentially toxic at higher concentrations, mainly due to the redox reactions in its transition state.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Comparative differential cuproproteomes of Rhodobacter capsulatus reveal novel copper homeostasis related proteins By feeds.rsc.org Published On :: Metallomics, 2020, 12,572-591DOI: 10.1039/C9MT00314B, PaperNur Selamoglu, Özlem Önder, Yavuz Öztürk, Bahia Khalfaoui-Hassani, Crysten E. Blaby-Haas, Benjamin A. Garcia, Hans-Georg Koch, Fevzi DaldalCuproproteome of model bacterium Rhodobacter capsulatus reveals 75 Cu-responsive proteins that are strongly influenced (2–300 fold) by Cu availability.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Investigation of the impact of magnesium versus titanium implants on protein composition in osteoblast by label free quantification By feeds.rsc.org Published On :: Metallomics, 2020, Advance ArticleDOI: 10.1039/D0MT00028K, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.M. Omidi, N. Ahmad Agha, A. Müller, F. Feyerabend, H. Helmholz, R. Willumeit-Römer, H. Schlüter, B. J. C. Luthringer-FeyerabendTo our knowledge, this is the first report describing and comparing the effects of magnesium and titanium biomaterials on human osteoblast proteome.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Diphenyl Diselenide Protects Caenorhabditis elegans Model for Huntington's Disease by Activation of Antioxidant Pathway and Decrease in Protein Aggregation By feeds.rsc.org Published On :: Metallomics, 2020, Accepted ManuscriptDOI: 10.1039/D0MT00074D, PaperFabiane Bicca Obetine Baptista, Marina Lopes Machado, Aline da Silva Franzen, Larissa Marafiga Cordeiro, Tassia da Silveira, Leticia Arantes, Félix A. A. SoaresHuntington’s disease (HD) is an autosomal dominant, progressive neurodegenerative disease with a distinct phenotype. It occurs due to a mutation in huntingtin (or IT19) gene with abnormal CAG repeat, leading...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Podcast: An 80-million-year-old dinosaur protein, sending oxygen to the moon, and competitive forecasting By traffic.omny.fm Published On :: Thu, 02 Feb 2017 14:00:00 -0500 This week, we chat about how the Earth is sending oxygen to the moon, using a GPS data set to hunt for dark matter, and retrieving 80-million year old proteins from dinosaur bones, with Online News Editor David Grimm. And Philip Tetlock joins Alexa Billow to discuss improving our ability to make judgments about the future through forecasting competitions as part of a special section on prediction in this week’s issue of Science. Listen to previous podcasts. [Image: NASA; Music: Jeffrey Cook] Full Article Scientific Community
protein A Stone Age skull cult, rogue Parkinson’s proteins in the gut, and controversial pesticides linked to bee deaths By traffic.omny.fm Published On :: Thu, 29 Jun 2017 16:00:00 -0400 This week we have stories on what the rogue Parkinson’s protein is doing in the gut, how chimps outmuscle humans, and evidence for an ancient skull cult with Online News Editor David Grimm. Jen Golbeck is back with this month’s book segment. She interviews Alan Alda about his new book on science communication: If I Understood You, Would I Have This Look on My Face? Sarah Crespi talks to Jeremy Kerr about two huge studies that take a nuanced looked at the relationship between pesticides and bees. Read the research in Science: Country-specific effects of neonicotinoid pesticides on honey bees and wild bees, B.A. Woodcock et al. Chronic exposure to neonicotinoids reduces honey bee health near corn crops, Tsvetkov et al. Listen to previous podcasts. [Image: webted/Flickr; Music: Jeffrey Cook] Full Article Scientific Community
protein DNA and proteins from ancient books, music made from data, and the keys to poverty traps By traffic.omny.fm Published On :: Thu, 27 Jul 2017 14:00:00 -0400 This week we hear stories on turning data sets into symphonies for business and pleasure, why so much of the world is stuck in the poverty trap, and calls for stiffening statistical significance with Online News Editor David Grimm. Sarah Crespi talks to news writer Ann Gibbons about the biology of ancient books—what can we learn from DNA, proteins, and book worm trails about a book, its scribes, and its readers? Listen to previous podcasts. [Music: Jeffrey Cook] Full Article
protein Fossilized dinosaur proteins, and making a fridge from rubber bands By traffic.omny.fm Published On :: Thu, 10 Oct 2019 15:15:00 -0400 Have you ever tried to scrub off the dark, tarlike residue on a grill? That tough stuff is made up of polymers—basically just byproducts of cooking—and it is so persistent that researchers have found similar molecules that have survived hundreds of millions of years. And these aren’t from cook fires. They are actually the byproducts of death and fossilization. Host Sarah Crespi talks with Contributing Correspondent Gretchen Vogel about how these molecules can be found on the surface of certain fossils and used as fingerprints for the proteins that once dwelled in dinos. And Sarah talks with Zunfeng Liu, a professor at Nankai University in Tianjin, China, about a new cooling technology based on a 100-year-old observation that a stretched rubber band is warm and a relaxed one is cool. It’s going to be hard to beat the 60% efficiency of compression-based refrigerators and air conditioning units, but Zunfeng and colleagues aim to try, with twists and coils that can cool water by 7°C when relaxed. This week’s episode was edited by Podigy. Ads on this week’s show: The Tangled Tree: A Radical New History of Life by David Quammen Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast Full Article Scientific Community
protein A deep learning approach to identify association of disease–gene using information of disease symptoms and protein sequences By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2016-2026DOI: 10.1039/C9AY02333J, PaperXingyu Chen, Qixing Huang, Yang Wang, Jinlong Li, Haiyan Liu, Yun Xie, Zong Dai, Xiaoyong Zou, Zhanchao LiPrediction of disease–gene association based on a deep convolutional neural network.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein A simple and rapid method for blood plasma separation driven by capillary force with an application on protein detection By feeds.rsc.org Published On :: Anal. Methods, 2020, Accepted ManuscriptDOI: 10.1039/D0AY00240B, PaperQingxue Gao, Yongjia Chang, Qingmei Deng, Hui YouBlood plasma separation is a vital sample pre-treatment procedure for microfluidic devices of blood diagnostic, which requires reliability and speediness. In this work, we propose a novel and simple method...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Selection and optimization of protein and carbohydrate assays for the characterization of marine biofouling By feeds.rsc.org Published On :: Anal. Methods, 2020, 12,2228-2236DOI: 10.1039/D0AY00272K, PaperChloe Richards, Nicole O'Connor, Diveena Jose, Alan Barrett, Fiona ReganBiofilms comprise a set of microorganisms attached to a surface through extracellular polymeric substances (EPS). Development of reliable analytical assays are valuable in determining the rate of biofilm attachment on surfaces.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Protein—fragment complex structures derived by NMR Molecular Replacement By feeds.rsc.org Published On :: RSC Med. Chem., 2020, Accepted ManuscriptDOI: 10.1039/D0MD00068J, Research Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Felix Torres, Dhiman Ghosh, Dean Strotz, Celestine Chi, Ben Davis, Julien OrtsRecently we have established an NMR Molecular Replacement method, which is capable of solving the structure of the interaction site of protein-ligand complexes in a fully automated manner. While the...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein Reversing binding sensitivity to A147T translocator protein By feeds.rsc.org Published On :: RSC Med. Chem., 2020, 11,511-517DOI: 10.1039/C9MD00580C, Research ArticleSophie V. Vo, Samuel D. Banister, Isaac Freelander, Eryn L. Werry, Tristan A. Reekie, Lars M. Ittner, Michael KassiouA loss in binding affinity at A147T relative to WT TSPO is seen with most TSPO ligands. Provision of hydrogen-bonding opportunities on indole carboxamides rescues this loss in affinity.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
protein [ASAP] High-Field Asymmetric Waveform Ion Mobility Spectrometry and Native Mass Spectrometry: Analysis of Intact Protein Assemblies and Protein Complexes By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.0c00649 Full Article
protein [ASAP] Structural Characterization of Individual a-Synuclein Oligomers Formed at Different Stages of Protein Aggregation by Atomic Force Microscopy-Infrared Spectroscopy By feedproxy.google.com Published On :: Fri, 01 May 2020 04:00:00 GMT Analytical ChemistryDOI: 10.1021/acs.analchem.0c00593 Full Article
