As of today, there are 3,230,433 coronavirus cases with 228,394 deaths. On a hopeful note, 1,007,136 have recovered. As the coronavirus pandemic takes an ever-larger toll across the world, extensive researches and surveys have been exploring who is at greatest risk

Stroke is ranked as the second leading cause of death and the third leading cause of disability worldwide, as per the World Health Organization. It is estimated that 70 per cent of stroke and 87 per cent of deaths caused by

Archives, Room Use Only - HE7677.M6 M36 1895

Archives, Room Use Only - TF64.L8 H43 1849

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Archives, Room Use Only - HE7677.M6 M67 1907

At the Ghazipur border, they huddled close together, only some with masks -- aware of the coronavirus threat that had led to an unprecedented 21-day lockdown of the country and taken away their jobs, but helpless to do anything about combating the infection.

The police registered a case against a person for negligent act likely to spread disease, and not having a pass to enter Udupi district on May 8. Acco

Workers rush to Tiruppur Railway Station, only to be disappointed

4.75 lakh e-tokens issued for liquor sale in Delhi

The Kuniyamuthur police here have registered a case against Naam Tamilar Katchi coordinator Seeman for allegedly speaking against the Central Governme

Residents speak of shock after being woken by EARTHQUAKE in early hours of morning  Hartlepool Mail

Invertebrates make up more than 80 percent of all known species and provide humans with a myriad of valuable services—from crop pollination to their use as food—yet they are overlooked and underrepresented in conservation decisions and on priority lists of threatened and endangered species.

The post Invertebrates are ignored, overlooked by conservationists, policymakers and the public appeared first on Smithsonian Insider.

Archan Chakraborty, Wei-Cheng Lin, Yu-Tsun Lin, Kuang-Jing Huang, Pei-Yu Wang, Yi-Feng Chang, Hsiang-Iu Wang, Kung-Ting Ma, Chun-Yen Wang, Xuan-Rong Huang, Yen-Hsien Lee, Bi-Chang Chen, Ya-Ju Hsieh, Kun-Yi Chien, Tzu-Yang Lin, Ji-Long Liu, Li-Ying Sung, Jau-Song Yu, Yu-Sun Chang, and Li-Mei Pai

Under metabolic stress, cellular components can assemble into distinct membraneless organelles for adaptation. One such example is cytidine 5'-triphosphate synthase (CTPS), which forms filamentous structures under glutamine deprivation. We have previously demonstrated that histidine (His)-mediated methylation regulates the formation of CTPS filaments to suppress enzymatic activity and preserve the CTPS protein under Gln deprivation, which promotes cancer cell growth after stress alleviation. However, it remains unclear where and how these enigmatic structures are assembled. Using CTPS-APEX2-mediated in vivo proximity labeling, we found that SNAP29 regulates the spatiotemporal filament assembly of CTPS along the cytokeratin network in a keratin 8 (KRT8)-dependent manner. Knockdown of synaptosome-associated protein 29 (SNAP29) interfered with assembly and relaxed the filament-induced suppression of CTPS enzymatic activity. Furthermore, APEX2 proximity labeling of keratin 18 (KRT18) revealed a spatiotemporal association of SNAP29 with cytokeratin in response to stress. Super-resolution imaging suggests that during CTPS filament formation, SNAP29 interacts with CTPS along the cytokeratin network. This study links the cytokeratin network to the regulation of metabolism by compartmentalization of metabolic enzymes during nutrient deprivation.

Tropical forests are a sometimes underappreciated asset in the battle against climate change. They cover 7 percent of land surface yet hold more than 30 […]

The post Vine-choked forests can’t capture carbon appeared first on Smithsonian Insider.

Fragments of crushed rock released into the ocean during oil and gas exploration can physically bury organisms that live on the seafloor, accounting for 55% of offshore drilling???s environmental impact, according to a recent study. To allow more informed marine policy decisions, this physical impact must be recognised alongside the impact of chemicals released in drilling waste.

Crop rotation is gaining increasing research- and policy attention as an environmentally friendly way to manage weeds. In such rotations, crops are introduced that release chemicals into the environment known to inhibit weed germination or growth (so-called allelopathic crops). Previous studies have identified Cynara cardunculus L., a perennial thistle, including varieties of globe artichoke and cardoon, as a potential allelopathic candidate. This study conducted field experiments using three botanical varieties of C. cardunculus to evaluate their effect on weeds within an ecosystem. The results confirm that C. cardunculus has an allelopathic effect in monoculture, reducing the amount of weed seeds present in soil. This paves the way for its inclusion in crop rotation as part of eco-friendly, sustainable weed-management strategies.

A new study by European researchers highlights the important contribution of greenhouse gases (GHGs) other than carbon dioxide to climate change and suggests policy measures to help reduce their impact. The study provides improved estimates of the current GHG balance of Europe, taking nitrous oxide and methane into account.

Inhaling smoke from forest, grass and peat fires causes about 340,000 premature deaths worldwide every year, according to new research. Reducing the number and extent of human-induced landscape fires could significantly improve air quality, mitigate climate change and reduce the rate of biodiversity loss, say scientists.

Particles from vehicle emissions are not the only traffic-related factor that causes deterioration of air quality in cities. Suspended road dust, caused by studded tyres, road salt and sand used in winter, may be at least as important in contributing to mortality rates, according to a new study in Stockholm, which suggests that these coarse particles should be controlled separately to fine particles.

Lesser kestrel (Falco naumanni) populations survive equally well in grassland and artichoke fields in Italy, a recent study has concluded. Overall, however, populations are declining and the researchers recommend reducing pesticide use, growing alternative crops such as artichokes, and maintaining grasslands as part of the farming landscape.

Increased black smoke pollution was associated with increased mortality rates almost a month after exposure in a recent study. The researchers studied death rates in relation to pollution concentrations over a 22-year period in the city of Glasgow, UK, and found significantly higher mortality rates among residents at 13-18 and 19-24 days after increased exposure to black smoke.

Road traffic noise and air pollution both increase the risk of having a stroke, recent research from Denmark suggests. The results suggest that traffic noise is more strongly associated with ischaemic stroke, whereas only air pollution appears to be linked with more serious, fatal strokes.

Exposure to gaseous and particulate matter pollution have been found to increase the immediate risk of stroke, a review of medical studies has shown. The increased risk is most pronounced the same day as the exposure, and for fine particles the increased risk persists over several days. The authors hope information from this study will help policymakers to develop suitable controls to limit the risks posed by these harmful air pollutants.

Jessica Mauboy needs connection with her family likes she needs oxygen. She usually travels from Sydney to Darwin every couple of weeks to spend time with her parents Therese and Ferdi, sisters Sandra, Jenny, Catherine and Sophia and her nieces and nephews.

SALEM – As part of the ongoing construction to replace the bridge over Back Creek on Route 220, an extended lane closure has been scheduled for next week. The bridge is near the intersection of Route 657 (Crowell Gap Road and Winter Drive).  Beginning Monday, October 8 at 9 a.m., the right northbound lane of Route 220 and the crossover at Crowell Gap Road will be closed until Wednesday, October 10 at 5 p.m. to pave a segment of the roadway that will connect to the new bridge. Drivers traveling on Route 220 northbound into Roanoke should expect significant delays on Route 220 during this time and are encouraged to plan their travel accordingly. The bridge replacement is expected to be complete in spring 2020. For updates on this project and other traffic impacts and lane closure, visit www.511Virginia.org .

SALEM – Route 220 north and south at Route 419 (Electric Road) in the Southern Hills area of Roanoke County is closed due to flooding. Drivers will need to seek alternate routes as the road will remain closed until the water recedes. Message boards are in place to alert motorists of the closure. Roads throughout the area may also experience flash flooding conditions as heavy rains continue through the evening. Drivers should use caution, drive with care and expect delays on their commute home from work today. If you see water across a road, turn around. Do not attempt to cross and or go around barricades that have closed a road. The Virginia Department of Transportation will be monitoring road conditions overnight. To report road conditions and downed trees, call 1-800-FOR-ROAD. For updates on this lane closure and others around the district, visit www.511Virginia.org . Follow us on Twitter for the latest updates in our region at @511southwestva and @VaDOTSalem.

SALEM – The left lane of southbound Route 220 is closed due to a slope failure in the median just south of the Franklin County line. The lane closure begins approximately one mile prior to  the Roanoke County and Franklin County line and just north of the intersection with Route 613 (Naff Road).   Drivers should prepare for travel delays and plan accordingly. Message boards are in place to alert motorists of the closure. The Virginia Department of Transportation is currently investigating to determine what repairs need to be made. The lane will remain closed until further notice.   For updates on this lane closure, visit www.511Virginia.org .

SALEM – The recent flooding and heavy rainfall has resulted in several slope and shoulder failures along Route 220 in Roanoke and Franklin Counties. During the next week, crews will be working to repair the damage and commuters and travelers will be impacted. Route 220 Southbound between Buck Mountain Road and Yellow Mountain Road in Roanoke County The right lane of southbound Route 220 is closed due to a slope failure on the right shoulder of the road between Buck Mountain and Yellow Mountain Road in Roanoke County.  High water from the heavy rains caused a rock slide that impacted the shoulder of the roadway. The weight caused the shoulder to collapse resulting in the road being pushed out and giving way. The right lane closure will remain in place through Monday evening, weather permitting. Crews are developing a plan to repair the pipe and plan to begin work over the weekend.   Route 220 Southbound at Franklin County Line The left lane of southbound Route 220 has been closed due to a slope failure in the median just south of the Franklin County line. VDOT crews have been working to determine how a pipe under the road has failed and how to proceed with repairs. At this time, the ground continues to settle and move, therefore, the lane will remain closed through the weekend and into Monday . The lane closure is located approximately one mile prior to the Roanoke County and Franklin County line and just north of the intersection with Route 613 (Naff Road).  Route 220 Shoulder Repairs There will be alternating right and left lane closures on southbound and northbound Route 220 next week, weather permitting, to repair shoulders that have been damaged by the heavy rainfall. Drivers using Route 220 southbound and northbound should plan ahead for significant delays during this time until repairs can be made and lane closures are removed. Drivers should plan ahead accordingly. For updates on this lane closure, visit www.511Virginia.org .

SALEM – In conjunction with the regularly scheduled fall transportation meeting for the Salem District, the third and final meeting in the series to receive input on the I-81 Corridor Improvement Plan will be held on October 25 at the Holiday Inn Valley View located at 3315 Ordway Drive NW in Roanoke. Prior to the Interstate 81 meeting, the fall transportation meeting will start at 2 p.m.  Attendees can view displays to learn about transportation planning, interact with subject matter experts, and review the proposed local and regional projects that have been submitted for scoring through SMART SCALE, an objective, data-driven prioritization process to score projects according to critical transportation needs. The Interstate 81 meeting will begin at approximately 3 p.m. and will focus on recommended projects and funding sources.   Following a presentation, there will be an opportunity for the public to provide comments about the I-81 study. Individual formal comment will be limited to three minutes. Feedback will be considered as team members finalize the I-81 corridor study and prepare a draft plan report in the fall.  Recommendations will be presented to the Commonwealth Transportation Board (CTB) for adoption prior to the opening of the 2019 General Assembly session. For those who cannot attend the meeting, comments can be submitted as follows:  Fall Transportation Meeting I-81 Corridor Improvement Plan Meeting Meeting materials will be available October 15 at www.ctb.virginia.gov/planning/fallmeetings/   The comment period ends on December 13.   Highway Comments VDOT Infrastructure Investment Director, Mail :  1401 East Broad Street, Richmond VA, 23219 Email :  Six-YearProgram@VDOT.Virginia.gov   Rail and Public Transit Comments DRPT Public Information Officer Mail :  600 East Main Street, Suite 2102, Richmond, VA 23219 Email :  DRPTPR@DRPT.Virginia.gov   Meeting materials will be available October 18 at www.VA81Corridor.org      The comment period ends on November 30   Send comments to Ben Mannell at   Mail :  1401 East Broad Street, Richmond VA, 23219   Email :  VA81CorridorPlan@OIPI.Virginia.gov        

SALEM – The Virginia Department of Transportation encourages race fans driving to and from Martinsville Speedway for the race on Sunday, October 28, to follow recommended traffic patterns as posted on signs and message boards. Drivers travelling from Roanoke to the Martinsville Speedway for the race events this weekend should plan for possible delays due to a left lane closure on Route 220 southbound approaching the Boones Mill area. VDOT will place many signs and changeable message boards throughout the region to assist travelers. Vehicular and pedestrian traffic will be heavy. Traffic is being routed to the speedway in certain patterns to minimize overall congestion as much as possible. Watch for the speed limit to reduce gradually from 65 mph to 35 mph on the Route 220/Route 58 Bypass as you approach the speedway. From Roanoke and areas north of Martinsville: Race fans traveling south on Route 220 are encouraged to allow for extra travel time. A left lane closure is in place for a pipe failure in the median about eight miles south of Roanoke and 1.7 miles north of Boones Mill. Drivers can take the exit onto Route 58 to Martinsville to reach the track or they can continue on the Route 220/Route 58 Bypass past the speedway interchange and turn right onto the access road that leads into the speedway. The entrance is located one mile east of the Route 220 interchange and may provide easier access. Signs are in place designating the entrance to the speedway.  From Danville and areas east of Martinsville: Motorists on the Route 58 Bypass should follow signs directing them to use the track’s back gate. This entrance is located off the bypass, east of the track. From Greensboro and areas south of Martinsville: Route 220 northbound traffic will split into three lanes shortly before reaching the speedway.  Motorists should watch for electronic message boards and obey police directing traffic. Through traffic should use the left lane. From Stuart and areas west of Martinsville: Motorists should stay on Route 58 east and follow signs and message boards to the track.  ADA Parking: Race fans needing ADA Parking are encouraged to enter the Speedway via Old Sand Roa Those attending the race should closely follow directional information and plan to arrive early and expect heavy traffic and delays. Martinsville Speedway has shared the attached graphics for drivers entering and exiting from the race.

Newark Mayor Cory Booker performs social media magic like no other politician.

Would someone get this man a superhero costume already?

How to help kids deal with unrequited love, a scarcity of cards, and broken hearts on Valentine's Day.

Thirdhand smoke is residual smoke and chemicals that linger in surfaces and still cause harm to people and animals.

Metaphysical services are disappearing from the online marketplace faster than you can say 'I bind you, Etsy, from doing harm ...'

Smoked watermelon "ham," the most bizarre viral dish of 2018, sets its sights on the holidays.

Artichokes have so much more potential than you might suspect.