engine Qantas plane from Perth forced to make emergency landing after experiencing 'engineering issue' By www.dailymail.co.uk Published On :: Thu, 16 Jan 2020 08:06:30 GMT Flight QF642 from Perth to Sydney took off about 9.30am on Thursday and was in the air for 58 minutes before having to make an emergency landing. Full Article
engine Qantas engineer who slapped a flight attendant on the bottom is sacked By www.dailymail.co.uk Published On :: Thu, 09 Apr 2020 04:43:17 GMT Luke Sikalias lost his claim for unfair dismissal at the Fair Work Commission after an incident before a flight from Melbourne to Sydney in May 2018. Full Article
engine Honda's S2000 sports car from a golden age of engineering: Cash Cars By www.dailymail.co.uk Published On :: Thu, 07 Feb 2019 09:56:51 GMT Buy a good Honda S2000 now for under £10,000 it should hold its value and reward you with many miles of high-revving fun, says Tony Middlehurst in our Cash Cars column. Full Article
engine Techno Electric And Engineering ... vs Central Electricity Regulatory ... on 5 March, 2020 By indiankanoon.org Published On :: Thu, 05 Mar 2020 00:00:00 +0530 Mr. Amit Kapur Ms. Poonam Verma Mr. Saunak Kumar Mr. Rajguru Mr. Sidhant Kaushik Ms. Aparajita Upadhyay Ms. Adhishree Chakraborty Ms. Sakshi Kapoor Counsel for the Respondent(s) : Ms. Abiha Zaidi for R-2 Order PER HON'BLE MR. S. D. DUBEY, TECHNICAL MEMBER IA No. 324 of 2020 Full Article
engine Oberoi Paints Pvt. Ltd vs Unilec Engineers Ltd on 6 May, 2020 By indiankanoon.org Published On :: Wed, 06 May 2020 00:00:00 +0530 2. Relevant facts are that plaintiff has filed suit for recovery against the defendant no.1 and 2. The case of the plaintiff, as set out in the plaint, is that plaintiff is a company registered under the Companies Act 1956 and is engaged in the manufacturing of coating powder and trading of decorative and industrial paints and thinner since 1994. The defendant is a limited company and registered under the Companies Act, 1956 and involved in the manufacturing of electrical panels. The defendant through its directors/ officials approached the plaintiff for purchase of the coating powder and industrial paints and thinner and at the time of commencement of the business, the terms of business, as specifically printed on or contained in the plaintiff's invoices were agreed by the defendant and thereafter business dealings and transactions started between the parites hereto in 2004 and since 15.04.2004 they have been maintaining a running account. Full Article
engine Barefoot, female and a Solar Engineer By indiatogether.org Published On :: Wed, 01 Jan 2003 00:00:00 +0000 The Social Work Research Centre addresses community problems by building upon people's skills, and placing the solutions in their own hands. Full Article
engine Scientific Consensus Shows Covid-19 'Not Genetically Engineered', India Funding Vaccine Development: DBT Secretary By www.news18.com Published On :: Sun, 10 May 2020 11:58:38 +0530 Ministry of Science and Technology's Department of Biotechnology (DBT) Dr Renu Swarup says that based on the latest WHO consensus, Covid-19 as a 'lab release' theory is likely to be false. Full Article
engine 2020 Nissan Kicks Gets New Turbo-Petrol Engine: नई निसान किक्स को मिला नया टर्बो-पेट्रोल इंजन By hindi.drivespark.com Published On :: Fri, 08 May 2020 12:46:36 +0530 नई निसान किक्स 2020 को अब और बेहतर और ताकतवर इंजन के साथ अपडेट किया गया है। कंपनी ने इस कार में नया टर्बो इंजन इस्तेमाल किया है। बता दें कि निसान ने अपनी दूसरी कंपनी रेनॉल्ट की डस्टर में इस टर्बो इंजन को पेश किया था। Full Article
engine 2020 Honda City To Feature New Petrol Engine: नई होंडा सिटी में मिलेगा 1.5 लीटर पेट्रोल इंजन By hindi.drivespark.com Published On :: Fri, 08 May 2020 22:14:54 +0530 होंडा (HONDA) भारत में नई सिटी को जल्द ही लाने वाली है। कंपनी ने धीरे धीरे अपने डीलरशिप खोलने शुरू कर दिए है तथा लॉकडाउन के खत्म होते ही नई सिटी की बिक्री शुरू की जा सकती है। नई होंडा सिटी Full Article
engine SSC CHSL, Junior Engineer And Stenographer Exams Postponed Due to Coronavirus By www.careerindia.com Published On :: Fri, 17 Apr 2020 12:33:24 +0530 The country is going through a national emergency due to the outbreak of Novel Coronavirus pandemic and hence is currently observing the lockdown till May 3, 2020. Most of the entrance exams along with board exams deferred due to COVID. There Full Article
engine SSC Results Postponed For Junior Engineer, MTS And CGL Due To Coronavirus By www.careerindia.com Published On :: Mon, 27 Apr 2020 16:06:46 +0530 The Staff Selection Commission (SSC) has announced that the results of various exams have been postponed due to the outbreak of Novel Coronavirus (COVID 19). The Commission has postponed the results of dates of Junior Engineer (Civil, Mechanical, Electrical and Quantity Full Article
engine New Honda City Will Feature 1.5-Litre Petrol Engine: Will Produce More Power By www.drivespark.com Published On :: Fri, 08 May 2020 19:36:12 +0530 The 2020 Honda City will be powered by an all-new 1.5-litre petrol engine in the Indian market. Apart from achieving BS6 compliance, the new engine is also expected to produce more power at lower RPMs as compared to the previous-gen model. Full Article
engine A textbook on telegraph engineering / International Correspondence Schools, Scranton, Pa By library.mit.edu Published On :: Sun, 19 Jan 2014 06:34:31 EST Archives, Room Use Only - TK5261.I58 1901 Full Article
engine Submarine telegraphy: instruction paper / presented by the engineers of the Western Union Telegraph Company By library.mit.edu Published On :: Sun, 19 Jan 2014 06:34:31 EST Archives, Room Use Only - TK5621.A44 1920 Full Article
engine McNeill's code: arranged to meet the requirements of mining, metallurgical and civil engineers; directors of mining, smelting and other companies; bankers; stock and share brokers; solicitors, accountants, financiers and general merchants: safety and By library.mit.edu Published On :: Sun, 2 Feb 2014 06:35:43 EST Archives, Room Use Only - HE7677.M6 M36 1895 Full Article
engine Sir William Preece, F.R.S.: Victorian engineer extraordinary / E. C. Baker By library.mit.edu Published On :: Sun, 9 Feb 2014 06:34:19 EST Archives, Room Use Only - TK140.P73 B34 1976 Full Article
engine Electricity in theory and practice, or, The elements of electrical engineering / by Bradley A. Fiske By library.mit.edu Published On :: Sun, 16 Feb 2014 06:33:42 EST Archives, Room Use Only - TK145.F57 1884 Full Article
engine Text book on telegraph cable engineering / [Eastern Associated Telegraph Companies] ; edited by J.H. Stephens By library.mit.edu Published On :: Sun, 2 Mar 2014 06:33:00 EST Archives, Room Use Only - TK5481.E27 1925 Full Article
engine Catalogue of the Wheeler gift of books, pamphlets and periodicals in the library of the American Institute of Electrical Engineers / edited by William D. Weaver ; with introduction, descriptive and critical notes by Brother Potamian By library.mit.edu Published On :: Sun, 16 Mar 2014 06:33:01 EDT Archives, Room Use Only - ZTK143.N532 Full Article
engine The life story of Sir Charles Tilston Bright, civil engineer: with which is incorporated the story of the Atlantic cable, and the first telegraph to India and the colonies / by Charles Bright By library.mit.edu Published On :: Sun, 27 Apr 2014 06:17:16 EDT Archives, Room Use Only - TK5611.B85 1910 Full Article
engine The history of the Institution of Electrical Engineers (1871-1931) / by Rollo Appleyard By library.mit.edu Published On :: Sun, 25 May 2014 06:33:02 EDT Archives, Room Use Only - TK1.I42 1939 Full Article
engine Submarine telegraphy / prepared by the Engineers of The Western Union Telegraph Company By library.mit.edu Published On :: Sun, 8 Jun 2014 06:17:54 EDT Archives, Room Use Only - TK5626.W47 1920 Full Article
engine McNeill's code: arranged to meet the requirements of mining, metallurgical and civil engineers; directors of mining, smelting and other companies; bankers; stock and share brokers; solicitors, accountants, financiers and general merchants: safety and By library.mit.edu Published On :: Sun, 22 Jun 2014 06:19:54 EDT Archives, Room Use Only - HE7677.M6 M36 1905 Full Article
engine Duplex and quadruplex telegraphy: instruction paper / prepared by the engineers of the Western Union Telegraph Company By library.mit.edu Published On :: Sun, 22 Jun 2014 06:19:54 EDT Archives, Room Use Only - TK5521.A44 1917 Full Article
engine The new general and mining telegraph code ...: alphabetically arranged for the use of mining companies, mining engineers, stockbrokers, financial agents, and trust and finance companies / by C. Algernon Moreing and Thomas Neal By library.mit.edu Published On :: Sun, 13 Jul 2014 06:17:13 EDT Archives, Room Use Only - HE7677.M6 M67 1907 Full Article
engine Modern electrical engineering / prepared under the editorship of Magnus Maclean By library.mit.edu Published On :: Sun, 27 Jul 2014 07:06:48 EDT Archives, Room Use Only - TK145.M334 1919 Full Article
engine Telegraphy and telephony with railroad applications / by Charles Stanley Rhoads ; a description of the fundamentals of telegraphy and telephony and of the organization, outside and inside plant, apparatus, circuits and methods of operation, engineering a By library.mit.edu Published On :: Sun, 27 Jul 2014 07:06:48 EDT Archives, Room Use Only - TK5262.R46 1924 Full Article
engine Telegraph repeaters: instruction paper / prepared by the Engineers of the Western Union Telegraph Company By library.mit.edu Published On :: Sun, 27 Jul 2014 07:06:48 EDT Archives, Room Use Only - TK5571.W47 1918 Full Article
engine District telegraph and time service: instruction paper / prepared by the Engineers of the Western Union Telegraph Company By library.mit.edu Published On :: Sun, 17 Aug 2014 07:36:28 EDT Archives, Room Use Only - TK5263.W468 1917 Full Article
engine History of the Engineering department / by E.C. Baker By library.mit.edu Published On :: Sun, 31 Aug 2014 08:18:07 EDT Archives, Room Use Only - HE6935.B35 1939 Full Article
engine London international telephone exchange: reproduced from the Post Office Electrical Engineers' Journal of July, 1934 / by S. Birch and C.H. Hartwell By library.mit.edu Published On :: Sun, 31 Aug 2014 08:18:07 EDT Archives, Room Use Only - TK6211.B57 1934 Full Article
engine Pioneer inventions and pioneer patents: a lecture on patent law delivered to the senior engineering students of Purdue University of the classes of '22, '23, and '24 and previous classes / by Frank Keiper By library.mit.edu Published On :: Sun, 14 Sep 2014 08:09:40 EDT Archives, Room Use Only - T223.Z1 K45 1924 Full Article
engine JavaScript engine fundamentals: Shapes and Inline Caches By mathiasbynens.be Published On :: Thu, 14 Jun 2018 12:57:44 +0200 This article describes some key fundamentals that are common to all JavaScript engines — and not just V8, the engine the authors work on. As a JavaScript developer, having a deeper understanding of how JavaScript engines work helps you reason about the performance characteristics of your code. Full Article
engine JavaScript engine fundamentals: optimizing prototypes By mathiasbynens.be Published On :: Thu, 16 Aug 2018 10:35:56 +0200 This article explains JavaScript engine optimization pipeline trade-offs, and describes how engines such as V8 speed up accesses to prototype properties. As a JavaScript developer, having a deeper understanding of how JavaScript engines work helps you reason about the performance characteristics of your code. Full Article
engine Chemical crystallography and crystal engineering By journals.iucr.org Published On :: Today, there is very little doubt that chemistry owes as much to crystallography as crystallography does to chemistry. This mutual synergy defines modern chemical crystallography. Full Article text
engine Interview: Michael Stephenson, British Geological Survey head of science & technology - The Engineer By www.theengineer.co.uk Published On :: Mon, 16 Jan 2017 08:00:00 GMT Interview: Michael Stephenson, British Geological Survey head of science & technology The Engineer Full Article
engine Geoenergy Observatory to go ahead in Cheshire - The Engineer By www.theengineer.co.uk Published On :: Mon, 08 Jul 2019 07:00:00 GMT Geoenergy Observatory to go ahead in Cheshire The Engineer Full Article
engine Engineering a surrogate human heteromeric α/β glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein By scripts.iucr.org Published On :: 2019-09-04 Protein-engineering methods have been exploited to produce a surrogate system for the extracellular neurotransmitter-binding site of a heteromeric human ligand-gated ion channel, the glycine receptor. This approach circumvents two major issues: the inherent experimental difficulties in working with a membrane-bound ion channel and the complication that a heteromeric assembly is necessary to create a key, physiologically relevant binding site. Residues that form the orthosteric site in a highly stable ortholog, acetylcholine-binding protein, were selected for substitution. Recombinant proteins were prepared and characterized in stepwise fashion exploiting a range of biophysical techniques, including X-ray crystallography, married to the use of selected chemical probes. The decision making and development of the surrogate, which is termed a glycine-binding protein, are described, and comparisons are provided with wild-type and homomeric systems that establish features of molecular recognition in the binding site and the confidence that the system is suited for use in early-stage drug discovery targeting a heteromeric α/β glycine receptor. Full Article text
engine Crystal engineering of exemestane to obtain a co-crystal with enhanced urease inhibition activity By scripts.iucr.org Published On :: 2020-01-01 Co-crystallization is a phenomenon widely employed to enhance the physio-chemical and biological properties of active pharmaceutical ingredients (APIs). Exemestane, or 6-methylideneandrosta-1,4-diene-3,17-dione, is an anabolic steroid used as an irreversible steroidal aromatase inhibitor, which is in clinical use to treat breast cancer. The present study deals with the synthesis of co-crystals of exemestane with thiourea by liquid-assisted grinding. The purity and homogeneity of the exemestane–thiourea (1:1) co-crystal were confirmed by single-crystal X-ray diffraction followed by thermal stability analysis on the basis of differential scanning calorimetry and thermogravimetric analysis. Detailed geometric analysis of the co-crystal demonstrated that a 1:1 co-crystal stoichiometry is sustained by N—H⋯O hydrogen bonding between the amine (NH2) groups of thiourea and the carbonyl group of exemestane. The synthesized co-crystal exhibited potent urease inhibition activity in vitro (IC50 = 3.86 ± 0.31 µg ml−1) compared with the API (exemestane), which was found to be inactive, and the co-former (thiourea) (IC50 = 21.0 ± 1.25 µg ml−1), which is also an established tested standard for urease inhibition assays in vitro. The promising results of the present study highlight the significance of co-crystallization as a crystal engineering tool to improve the efficacy of pharmaceutical ingredients. Furthermore, the role of various hydrogen bonds in the crystal stability is successfully analysed quantitatively using Hirshfeld surface analysis. Full Article text
engine Forthcoming article in Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials By journals.iucr.org Published On :: Full Article Still image
engine Engineering the Fab fragment of the anti-IgE omalizumab to prevent Fab crystallization and permit IgE-Fc complex crystallization By scripts.iucr.org Published On :: 2020-03-02 Immunoglobulin E (IgE) plays a central role in the allergic response, in which cross-linking of allergen by Fc∊RI-bound IgE triggers mast cell and basophil degranulation and the release of inflammatory mediators. The high-affinity interaction between IgE and Fc∊RI is a long-standing target for therapeutic intervention in allergic disease. Omalizumab is a clinically approved anti-IgE monoclonal antibody that binds to free IgE, also with high affinity, preventing its interaction with Fc∊RI. All attempts to crystallize the pre-formed complex between the omalizumab Fab and the Fc region of IgE (IgE-Fc), to understand the structural basis for its mechanism of action, surprisingly failed. Instead, the Fab alone selectively crystallized in different crystal forms, but their structures revealed intermolecular Fab/Fab interactions that were clearly strong enough to disrupt the Fab/IgE-Fc complexes. Some of these interactions were common to other Fab crystal structures. Mutations were therefore designed to disrupt two recurring packing interactions observed in the omalizumab Fab crystal structures without interfering with the ability of the omalizumab Fab to recognize IgE-Fc; this led to the successful crystallization and subsequent structure determination of the Fab/IgE-Fc complex. The mutagenesis strategy adopted to achieve this result is applicable to other intractable Fab/antigen complexes or systems in which Fabs are used as crystallization chaperones. Full Article text
engine Wanted to do software engineering. By www.bleepingcomputer.com Published On :: 2019-05-27T07:48:04-05:00 Full Article
engine 5 Reasons the Inka Road is one of the Greatest Achievements in Engineering By insider.si.edu Published On :: Wed, 20 May 2015 18:12:20 +0000 The Inka Empire is one of the greatest civilizations in the Western Hemisphere, spanning from the 13th century until the Spanish invasion in 1532. To […] The post 5 Reasons the Inka Road is one of the Greatest Achievements in Engineering appeared first on Smithsonian Insider. Full Article Anthropology History & Culture South America technology
engine Next Engineering Revolution Is Hiding in Museum Collections By insider.si.edu Published On :: Fri, 10 Jun 2016 18:00:21 +0000 Engineers shouldn’t have to reinvent the wheel—or wings, or sonar systems—when mother nature has already done much of the heavy design work. In fact, finding […] The post Next Engineering Revolution Is Hiding in Museum Collections appeared first on Smithsonian Insider. Full Article Animals Plants Science & Nature bats birds digitization insects mammals National Museum of Natural History
engine 21 Centurys Grand Engineering Challenges Unveiled By feedproxy.google.com Published On :: Fri, 15 Feb 2008 06:00:00 GMT The U.S. National Academy of Engineering (NAE) today announced the grand challenges for engineering in the 21st century. A diverse committee of experts from around the world, convened at the request of the U.S. National Science Foundation, revealed 14 challenges that, if met, would improve how we live. Full Article
engine Genetically Engineered Crops Benefit Many Farmers, but the Technology Needs Proper Management to Remain Effective By feedproxy.google.com Published On :: Tue, 13 Apr 2010 05:00:00 GMT Many U.S. farmers who grow genetically engineered (GE) crops are realizing substantial economic and environmental benefits -- such as lower production costs, fewer pest problems, reduced use of pesticides, and better yields -- compared with conventional crops, says a new report from the National Research Council. Full Article
engine National Academy of Engineering Elects 67 Members and 11 Foreign Associates By feedproxy.google.com Published On :: Thu, 06 Feb 2014 06:00:00 GMT The National Academy of Engineering (NAE) has elected 67 new members and 11 foreign associates, announced NAE President C.D. (Dan) Mote Jr. today. This brings the total U.S. membership to 2,250 and the number of foreign associates to 214. Full Article
engine Genetically Engineered Crops - Experiences and Prospects By feedproxy.google.com Published On :: Tue, 17 May 2016 05:00:00 GMT An extensive study by the National Academies of Sciences, Engineering, and Medicine has found that new technologies in genetic engineering and conventional breeding are blurring the once clear distinctions between these two crop-improvement approaches. Full Article
engine New Report Examines Role of Engineering Technology, Calls for Increased Awareness of Field of Study and Employment By feedproxy.google.com Published On :: Wed, 15 Feb 2017 06:00:00 GMT While workers in the engineering technology (ET) field play an important role in supporting U.S. technical infrastructure and the country’s capacity for innovation, there is little awareness of ET as a field of study or category of employment in the U.S., says a new report from the National Academy of Engineering. Full Article
engine Statement by the National Academies of Sciences, Engineering, and Medicine regarding PLOS ONE article on our study of genetically engineered crops By feedproxy.google.com Published On :: Wed, 01 Mar 2017 06:00:00 GMT The National Academies Committee on Genetically Engineered Crops - Past Experiences and Future Prospects authored an almost 600-page landmark report, released in May 2016. It was perhaps the most comprehensive analysis of genetically engineered crops to date. Full Article