The bio-based medical-grade PVC compounds utilize resins and plasticizers manufactured with renewable energy and bio-attributed classification. 

Between strict energy codes and residing in a high-wind area, installing solar on a multi-roof family compound in Boulder, Colo. proved to be a challenge.

We think they had a baby named Gateau Breton.

The post The day pound cake married shortbread first appeared on Federal News Network.

Meat producer BrucePac is recalling nearly 10 million pounds of meat and poultry products sold at Trader Joe's, Target, Kroger and other retailers because they might be contaminated with listeria.

Berkeley chemists have created a reusable material that pulls carbon dioxide from the air and holds onto it until it can be stored.

Scientists advance Parkinson’s disease biomarker research one sniff at a time.

Wylie Hunter refuses to give up…

We'll continue to invest in our brand, technology, products, and grow our offline online touchpoints. We are going to open around 350 stores over the next three years and grow our multi-channel competitive strengths. We will also enhance our in-house brands and their distribution through pharmacies and grocery stores. We also plan to invest in manufacturing, international markets and Globalbees, our brand aggregator platform,Supam Maheshwari, cofounder and CEO of FirstCry said.

The cruelty is the point with these disgusting excuses for human beings. Maybe they can do something about illegal immigrant Elon while they're at it. The incompetent first Trump administration got their rear ends handed to them during their last attempt to deport all of the DREAMers who were living in the United States under the Deferred Action for Childhood Arrivals program, otherwise known as DACA.

Now they're ready to do it again with Trump's plans for mass deportations, that would destroy the United States' economy.

Trump supporter Vivek Ramaswamy, who could end up with a job in the Trump administration, made an appearance on ABC's This Week, and was asked about whether Trump would actually follow through with his threat or not, and when host Jonathan Karl brought up the DREAMers, who were brought here as children, Ramaswamy basically told them all to pound sand.

KARL: Now, obviously, Trump's promised --and you've talked a lot about this, the -- you know, mass deportation of undocumented immigrants.

read more

Full Article

There are laptops sold with NVidia's high-end 4090 graphics chip, but it's a power-constrained mobile version appropriate for portable machines. A Chinese-language blogger modded themselves a beast of a machine with a full desktop-class 4090 card. This thing weighs 15 pounds and its battery life is a Borgesian map of nothing (one must plug it in). — Read the rest

The post "Laptop" with full 4090 GPU weighs 15 pounds appeared first on Boing Boing.

Centrioles are key eukaryotic organelles that are responsible for the formation of cilia and flagella, and for organizing the microtubule network and the mitotic spindle in animals. Centriole assembly requires oligomerization of the essential protein spindle assembly abnormal 6 (SAS-6), which forms a structural scaffold templating the organization of further organelle components. A dimerization interaction between SAS-6 N-terminal “head” domains was previously shown to be essential for protein oligomerization in vitro and for function in centriole assembly. Here, we developed a pharmacophore model allowing us to assemble a library of low-molecular-weight ligands predicted to bind the SAS-6 head domain and inhibit protein oligomerization. We demonstrate using NMR spectroscopy that a ligand from this family binds at the head domain dimerization site of algae, nematode, and human SAS-6 variants, but also that another ligand specifically recognizes human SAS-6. Atomistic molecular dynamics simulations starting from SAS-6 head domain crystallographic structures, including that of the human head domain which we now resolve, suggest that ligand specificity derives from favorable Van der Waals interactions with a hydrophobic cavity at the dimerization site.

Costco voluntarily recalled 79,200 pounds of two types of its store-brand butter over the past month because their labels may not have said the products contain milk.

Costco voluntarily recalled 79,200 pounds of two types of its store-brand butter over the past month because their labels may not have said the products contain milk.

Travis Gienger, who nicknamed his prize-winning pumpkin "Rudy," has been growing gourds for nearly 30 years

The pound stabilised on Friday after a volatile few sessions, but still headed for its longest stretch of weekly losses in nearly six years, as political and monetary uncertainty has prompted investors to favour the dollar lately.

Panel: Compound Climate Threats Increase Need for Regional Cooperation in the Pacific Panel: Compound Climate Threats Increase Need for Regional Cooperation in the Pacific

While operating in the area, soldiers from the Shaldag Unit identified several tunnel shafts leading to the compound, which led to the exposure of the full tunnel. 

Title: Excess Pounds Raise Risk of Breast Cancer Recurrence, Death: Study
Category: Health News
Created: 8/27/2012 10:05:00 AM
Last Editorial Review: 8/27/2012 12:00:00 AM

Title: 30 Minutes of Daily Exercise Enough to Shed Pounds
Category: Health News
Created: 8/25/2012 11:00:00 AM
Last Editorial Review: 8/27/2012 12:00:00 AM

Title: Less Sleep in Teen Years Tied to More Pounds at 21
Category: Health News
Created: 8/28/2014 4:36:00 PM
Last Editorial Review: 8/29/2014 12:00:00 AM

Title: Diabetes Drug May Help Kids With Autism Fight Unwanted Pounds
Category: Health News
Created: 8/24/2016 12:00:00 AM
Last Editorial Review: 8/25/2016 12:00:00 AM

Title: Brain Scans Offer Clues to Why Some Teens Pile on Pounds
Category: Health News
Created: 8/31/2017 12:00:00 AM
Last Editorial Review: 9/1/2017 12:00:00 AM

Title: Too Little Sleep Could Have Teens Piling on Pounds
Category: Health News
Created: 8/24/2022 12:00:00 AM
Last Editorial Review: 8/24/2022 12:00:00 AM

Compound probiotics have been widely used and commonly coadministered with other drugs for treating various chronic illnesses, yet their effects on drug pharmacokinetics remain underexplored. This study elucidated the impact of VSL#3 on the metabolism of probe drugs for cytochrome P450 enzymes (P450s), specifically omeprazole, tolbutamide, midazolam, metoprolol, phenacetin, and chlorzoxazone. Male Wistar rats were administered drinking water containing VSL#3 or not for 14 days and then intragastrically administered a P450 probe cocktail; this was done to investigate the host P450’s metabolic phenotype. Stool, liver/jejunum, and serum samples were collected for 16S ribosomal RNA sequencing, RNA sequencing, and bile acid profiling. The results indicated significant differences in both α and β diversity of intestinal microbial composition between the probiotic and vehicle groups in rats. In the probiotic group, the bioavailability of omeprazole increased by 269.9%, whereas those of tolbutamide and chlorpropamide decreased by 28.1% and 27.4%, respectively. The liver and jejunum exhibited 1417 and 4004 differentially expressed genes, respectively, between the two groups. In the probiotic group, most of P450 genes were upregulated in the liver but downregulated in the jejunum. The expression of genes encoding metabolic enzymes and drug transporters also changed. The serum-conjugated bile acids in the probiotic group were significantly reduced. Shorter duodenal villi and longer ileal villi were found in the probiotic group. In summary, VSL#3 administration altered the gut microbiota, host drug–processing gene expression, and intestinal structure in rats, which could be reasons for pharmacokinetic changes.

BEIRUT/JERUSALEM — The Israeli military pounded Beirut's southern suburbs with airstrikes on Tuesday (Nov 12), mounting one of its heaviest daytime attacks yet on the Hezbollah-controlled area, and struck the middle of the country where more than 20 people were killed. Smoke billowed over Beirut as around a dozen strikes hit the southern suburbs starting in midmorning. After posting warnings to civilians on social media, the Israeli military said it struck Hezbollah targets in Beirut's Dahiyeh area and later said it dismantled most of the group's weapons and missile facilities. Israel said it had taken steps to reduce harm to civilians and repeated its standing accusation that Hezbollah deliberately embeds itself into civilian areas to use residents as human shields, a charge Hezbollah rejects. In northern Israel, two people were killed in the city of Nahariya when a residential building was struck, Israeli police said. Hezbollah later claimed responsibility for a drone attack that it said was aimed at a military base east of Nahariya.

Guidelines for Compounding of Offences under the IT Act 1961

In a tragic incident that highlights the dire consequences of medlinkmedical negligence/medlink, a 28-year-old woman lost her life during a sterilization

A team of research scientists said that they have developed a male oral contraceptive pill that didn't cause observable side effects, with the drug expected to enter human trials by the end of 2022.

Periodontal disease or periodontitis is a significant inflammatory condition triggered by an infection from periodontal pathogens. This condition not

INSIGHT - The Consumer Magazine (September-October 2007) , published by Consumer Education and Research Society (CERS),

London : Methuen Drama, 2022.

The resort town of Interlaken is not just about idyllic lake cruises

Researchers from Saint Louis University in the United States have said that curcumin, an active ingredient in the spice, holds promise in treating such cancers.