Agora integrates with OpenAI to enable real-time conversational AI.

Es la única aseguradora que no licita ya a ningún concurso sanitario para empleados públicos, al calcular que el planteamiento del ministro y Hacienda duplicaba lo ya perdido hasta ahora Leer

De la vicepresidenta de Ingeniería de Seguridad de Google depende la estrategia de defensa ante ataques cibernéticos. Ayer defendió el uso de la inteligencia artificial para este cometido en un congreso en Málaga Leer

The 2024 Cinetopia Film Festival rolls on in Ann Arbor! Marquee Arts executive director Russ Collins joins WEMU's David Fair to provide an update on the film fest and the new films opening downtown. Plus, Russ brings along filmmaker and Eastern Michigan University alumnus Heidi Philipsen, who talks about her film "Love & Vodka," which closes out Cinetopia this weekend!

Bermudian runner Cameron Adkins achieved a personal best time at the Eye-Opener Cross Country Meet in Spartanburg, South Carolina, helping his Christ School team to a sixth-place finish. Adkins crossed the line in 16:37.90, securing 53rd place in a competitive field within the international boys division. Christ School, with a total of 255 points, finished […]

Cameron Adkins and his Christ School men’s cross country teammates competed in the North Carolina High School Athletic Association [NCHSAA] Cross Country Championships. Christ School competing in the 4A Boys 5k finished 9th with 223 points, this after Adkins finished 64th with a time of 17:54. Related Stories Armstrong Competes In MAAC Championships Marshall & […]

Cameron Adkins made his Christ School debut, competing in the Brevard High School Two-Mile Preseason Cross Country Meet. Adkins clocked a time of 10:14 to finish 7th overall, he was the 4th Christ School runner to cross the line as they claimed all three spots on the podium. Related Stories Prunty Claims Victory At AXA […]

In addition to their well-known role in the control of cellular proliferation and cancer, cell cycle regulators are increasingly identified as important metabolic modulators. Several GWAS have identified SNPs near CDKN2A, the locus encoding for p16INK4a (p16), associated with elevated risk for cardiovascular diseases and type-2 diabetes development, two pathologies associated with impaired hepatic lipid metabolism. Although p16 was recently shown to control hepatic glucose homeostasis, it is unknown whether p16 also controls hepatic lipid metabolism. Using a combination of in vivo and in vitro approaches, we found that p16 modulates fasting-induced hepatic fatty acid oxidation (FAO) and lipid droplet accumulation. In primary hepatocytes, p16-deficiency was associated with elevated expression of genes involved in fatty acid catabolism. These transcriptional changes led to increased FAO and were associated with enhanced activation of PPARα through a mechanism requiring the catalytic AMPKα2 subunit and SIRT1, two known activators of PPARα. By contrast, p16 overexpression was associated with triglyceride accumulation and increased lipid droplet numbers in vitro, and decreased ketogenesis and hepatic mitochondrial activity in vivo. Finally, gene expression analysis of liver samples from obese patients revealed a negative correlation between CDKN2A expression and PPARA and its target genes. Our findings demonstrate that p16 represses hepatic lipid catabolism during fasting and may thus participate in the preservation of metabolic flexibility.

Premiered on October 6, Bigg Boss 18 is hosted by Salman Khan

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Continue reading "Andrew Hulshult 2024 Interview: DOOM IDKFA, Blood Swamps, DUSK, Iron Lung, AMID EVIL, Music, Guitars, Cold Brew Coffee, and More"

New Amsterdam Vodka presents "It's Your Town"

Some farmers say studies suggest Paraquat could be a factor in the onset of Parkinson's Disease.

NIDDK and ORWH Team Up For Mother's Day and National Women's Health Week to Raise Awareness of Gestational Diabetes and

Bigg Boss 18: The addition of actress Shilpa Shirodkar making a comeback through the reality series was something that left quite some buzz. However, the impact seems to have fizzled out with time.

1. This bail application has been filed by the accused-petitioner under Section 483 B.N.S.S., in connection with F.I.R. No.287/2024, registered at the Police Station Adarshnagar Jaipur City (East), District Jaipur City (East) for the offences punishable under Sections 140(2) & 142 of BNS.

2. Counsel for the petitioner submits that the accused- petitioner has falsely been implicated in this matter. Counsel further submits that co-accused have already been enlarged on bail by this Court on 25.10.2024. Counsel further submits that the accused-petitioner is in custody since long time. He is no more required for any kind of interrogation or recovery, therefore, the petitioner may be released on bail.

Majhi Ladki Bahin Yojana: देश भर में महिलाओं को सशक्त बनाने के प्रयास में भारत सरकार ने विभिन्न राज्य सरकारों के साथ मिलकर कई योजनाएं शुरू की हैं। इनमें से माझी लड़की बहिन योजना सबसे अलग है, खासकर महाराष्ट्र में जहां

On Friday, Union Minister Nitin Gadkari said that the government is planning to create a deposit-taking 'social microfinance organisation' to disburse loans of up to Rs 10 lakh to women and small entrepreneurs quickly. The Minister for MSME and Road

On Saturday, Union minister for micro, small and medium enterprises (MSME) Nitin Gadkari said that the government will consider increasing import duty on products from some sectors to support domestic businesses. Without specifying these sectors, Gadkari at the India @75 summit

Union Minister Nitin Gadkari slammed the Congress for claiming the BJP will change the country's Constitution. The Maharashtra assembly polls will be held on November 20 and votes will be counted on November 23.

Manchester : Manchester University Press, [2019]

New York, NY : Routledge, 2020

Tells Maharashtra CM to protect Mumbai from water, air pollution

Deputy CM Ajit Pawar tours Baramati villages, addresses key issues ahead of elections and assures continuation of popular schemes

The Maharashtra government rolled out the Majhi Ladki Bahin Yojana in August 2024 and is counting on it to gather votes from women. Ever since the scheme was introduced and beneficiaries began thronging banks, there have been several attacks on public sector bank employees. Vinaya Deshpande Pandit reports on a scheme that has caused law and order problems and created fear among employees

For farmers, the Nationalist Congress Party promised to raise the Shetkari Sanman Nidhi scheme amount from ₹12,000 to ₹15,000 per year.

Skill census, stipend for students, loan waiver to farmers, food and shelter to all the poor some of the highlights

Actor and martial artist Scott Adkins uses the power of Twitter to answer the internet's burning questions about martial arts training. How do MMA fighters take kicks to the shin? How does one get a body like Yuri Boyka? Should you ever let an attacker know you are trained in martial arts? Scott answers all these questions and much more!

Kakodkar spoke about BSR development and a new type of fuel, ANEEL — a concoction of highly enriched uranium and thorium that is making waves in the nuclear energy sector

'One thing I really lack as an actor is angst. I'm not an angry person. I'm a very fun-loving, happy, detached guy.'

The top court’s judgment takes into account the different sociological realities of every ‘jati’ with the aim of addressing the disparity within Scheduled Castes

Gadkari highlighted the significance of efficient highways, waterways, and railways in reducing logistics costs and stimulating economic growth.

Devendra Fadnavis says BJP leader’s name will be first when Maharashtra list candidates are announced

Sukanya Verma looks at their eclectic career of over two decades as their latest offering Citadel: Honey Bunny, the Indian leg of the Russo Brothers globetrotting spy universe series, drops on Amazon Prime Video on November 7.

“In addition to brining in transparency, the bodycams will make police personnel more conscious and improve their conduct with people,” Mangaluru Police Commissioner Anupam Agrawal said

After Prime Minister Narendra Modi accused the Congress government of collecting ₹700 crore from excise sources to fund the Maharashtra elections, it was the turn of N. Cheluvarayaswamy

They held that the State government had already spent nearly ₹75 crore for strengthening alternate route via Hunsur-Gonikoppa-Kutta

But an uphill task for Rest of India still, chasing 480 in the fourth innings

According to quick estimates of the economic think tank National Council of Applied Economic Research (NCAER), logistics costs in India ranged between 7.8% to 8.9% of GDP for the fiscal 2021-22

In an interview with The Hindu, Mr. Gadkari said the BJP remains united in its ideological commitment, with no discord between the party and the RSS.

Maharashtra Chief Minister accuses Congress of copying its flagship popular scheme ‘Mukhyamantri Majhi Ladki Bahin Yojana’ while announcing the five guarantees in Mumbai; welfare schemes of ruling alliance benefit everyone, he says

This is a sixfold increase compared to the demand seen last year

The agreement will see Acer designing, manufacturing, and distributing smartphones under its brand, focusing on models priced between ₹15,000 and ₹50,000