Air Force Secretary Frank Kendall said the branch is looking toward confronting China, as well as unity in its ranks, and added that the service needs to retire older aircraft and programs -- and focus on ones that work.

Abnormal neuronal morphological features, such as dendrite branching, axonal branching, and spine density, are thought to contribute to the symptoms of depression and anxiety. However, the role and molecular mechanisms of aberrant neuronal morphology in the regulation of mood disorders remain poorly characterized. Here, we show that neuritin, an activity-dependent protein, regulates the axonal morphology of serotonin neurons. Male neuritin knock-out (KO) mice harbored impaired axonal branches of serotonin neurons in the medial prefrontal cortex and basolateral region of the amygdala (BLA), and male neuritin KO mice exhibited depressive and anxiety-like behaviors. We also observed that the expression of neuritin was decreased by unpredictable chronic stress in the male mouse brain and that decreased expression of neuritin was associated with reduced axonal branching of serotonin neurons in the brain and with depressive and anxiety behaviors in mice. Furthermore, the stress-mediated impairments in axonal branching and depressive behaviors were reversed by the overexpression of neuritin in the BLA. The ability of neuritin to increase axonal branching in serotonin neurons involves fibroblast growth factor (FGF) signaling, and neuritin contributes to FGF-2-mediated axonal branching regulation in vitro. Finally, the oral administration of an FGF inhibitor reduced the axonal branching of serotonin neurons in the brain and caused depressive and anxiety behaviors in male mice. Our results support the involvement of neuritin in models of stress-induced depression and suggest that neuronal morphological plasticity may play a role in controlling animal behavior.

The superior colliculus receives a direct projection from retinal ganglion cells. In primates, it remains unknown if the same ganglion cells also supply the lateral geniculate nucleus. To address this issue, a double-label experiment was performed in two male macaques. The animals fixated a target while injection sites were scouted in the superior colliculus by recording and stimulating with a tetrode. Once suitable sites were identified, cholera toxin subunit B-Alexa Fluor 488 was injected via an adjacent micropipette. In a subsequent acute experiment, cholera toxin subunit B-Alexa Fluor 555 was injected into the lateral geniculate nucleus at matching retinotopic locations. After a brief survival period, ganglion cells were examined in retinal flatmounts. The percentage of double-labeled cells varied locally, depending on the relative efficiency of retrograde transport by each tracer and the precision of retinotopic overlap of injection sites in each target nucleus. In counting boxes with extensive overlap, 76–98% of ganglion cells projecting to the superior colliculus were double labeled. Cells projecting to the superior colliculus constituted 4.0–6.7% of the labeled ganglion cell population. In one particularly large zone, there were 5,746 cells labeled only by CTB-AF555, 561cells double labeled by CTB-AF555 and CTB-AF488, but no cell labeled only by CTB-AF488. These data indicate that retinal input to the macaque superior colliculus arises from a collateral axonal branch supplied by ~5% of the ganglion cells that project to the lateral geniculate nucleus. Surprisingly, there exist no ganglion cells that project exclusively to the SC.

Did you know? The Publications and Library branch and the FSN Forum are teaming up to provide Forum participants with additional references and resources to raise awareness on topics of their contributions.

Who does what 

The Global Forum on Food [...]

Even as they fundraise for other community organizations, some legions across Canada are having trouble keeping their own lights on amid rising inflation and maintenance costs.

The P.E.I. Woodlot Owners Association is encouraging its members to boost the biodiversity of their woods with different varieties of trees and shrubs. As CBC's Nancy Russell reports, the goal is to provide habitat for endangered species and protect the forests from future disasters like post-tropical storm Fiona.

Public Schools Branch director Tracy Beaulieu speaks with CBC News: Compass host Steve Bruce about the money for schools in the new capital budget the province presented last week, and about the work that lies ahead.

Dozens of arborists and professionals from three Delaware tree care companies volunteered for the 7th Annual "Saluting Branches" event by devoting a day to trimming, shaping, and removing hazardous trees from the Delaware Veterans Memorial Cemetery in Millsboro. The Delaware site was one of 40 sites throughout the United States that participated in the event, which attracted more than 3,000 volunteers. Workers from Tri-State Tree Care, Complete Tree Care, and Cypress Tree Care spent their entire day as a way to pay tribute to the veterans and their service.

Soil core samples show an ancient riverbed under the desert near many Egyptian pyramids, revealing an ancient waterway that dried up thousands of years ago

The spliceosome is a eukaryotic multimegadalton RNA–protein complex that removes introns from transcripts. The spliceosome ensures the selection of each exon-intron boundary through multiple recognition events. Initially, the 5' splice site (5' SS) and branch site (BS) are bound by the U1 small nuclear ribonucleoprotein (snRNP) and the U2 snRNP, respectively, while the 3' SS is mostly determined by proximity to the branch site. A large number of splicing factors recognize the splice sites and recruit the snRNPs before the stable binding of the snRNPs occurs by base-pairing the snRNA to the transcript. Fidelity of this process is crucial, as mutations in splicing factors and U2 snRNP components are associated with many diseases. In recent years, major advances have been made in understanding how splice sites are selected in Saccharomyces cerevisiae and humans. Here, I review and discuss the current understanding of the recognition of splice sites by the spliceosome with a focus on recognition and binding of the branch site by the U2 snRNP in humans.

As many as 115 Post Office Branches and hundreds of jobs could be at risk following a strategic review held by Post Office Chairman Nigel Railton.

Hundreds of head office workers are facing cuts and loss-making branches are under threat of closure.

Heard both sides.

https://www.mhc.tn.gov.in/judis

2. The Petitioner is the State Bank of India represented by its Branch Manager at their Zonal Office, Trichirappalli. Aggrieved by the common award passed by the First Respondent Central Government Industrial Tribunal (CGIT) at Chennai made in I.D.No.22 to 25 of 2007 dt. 27.7.2010 these writ petitions were filed by them.

3. The 1st Respondent CGIT by its Common Award granted the following relief to the 2nd Respondent workmen in all the WPs:-

“In the result all the petitioners in ID 22/2007, 23/2007, 24/2007 and ID 25/2007 are entitled to be reinstated into service forthwith with continuity of service and all attendant benefits but they are not entitled to back-wages for the whole period during which they remained out of employment of Respondent. After reinstatement into service the Management may start a process for the regularization of the workmen if and in accordance with the rules in vogue they are entitled to the same.”

Most developers spoil themselves with fun command line utilities to make their work easier and more efficient. One such command line helper allows developers to always show the git branch in the command line. How can you get the current branch? With this handy snippet: git branch --show-current It’s great to keep this snippet around […]

The post How to Get the Current Branch Name with git appeared first on David Walsh Blog.

Singapore : Horizon Books, 2002.

[U.K.] : TLA Releasing, [2011]

[Hong Kong] : Royal Asiatic Society, Hong Kong Branch

[Hong Kong] : Royal Asiatic Society, Hong Kong Branch

From financial inclusion to wooing back savings deposits, lenders have reasons to reject digital-only mode

BoB Chief Debadatta Chand says FY25 credit, deposit growth targets revised down to balance CD ratio

Earlier in 2024, Sundaram Home Finance bolstered its presence in non-South regions with branch openings in Mumbai and Kota, Rajasthan

Union Bank of India opens Nari Shakti branches in Bengaluru, Chennai, Visakhapatnam, and Jaipur

>. Learned counsel for the appellants has also filed written notes of arguments and in reply a further written note of arguments has been filed by learned counsel for the respondent. The respondent, as an account holder in the State Bank of India (SBI), suffered a loss of Rs. 18,35 lakh through 20 internet transactions and the money was transferred to 20 accounts, all with the SBI. The account holder/complainant filed Petition No. 1 of 2013 before the leamed A.O./Secretary to Government, Information Technology, Electronics and Communications Department, Government of Andhra Pradesh. After hearing the parties in detail and taking into consideration the defence of the Bank, which is the appellants herein, and all the relevant documents, learned A.O. by the impugned order dated 12,3.2014 has allowed claim of the complainant who is respondent herein and directed SBI to pay the entire amount of Rs. 18.35 lakh with interest from the date of loss ie. 13.5.2012 till the date of payment along with the costs of Rs. 39,750.00. The rate of interest is 18% per annum. Admittedly, nothing has been paid by SBI so far.

2. Brief facts necessary to be noticed for deciding this petition are that in the above dispute raised under the provisions of the Industrial Disputes Act, 1947, the Labour court was called upon to adjudicate a reference wherein the issue was "whether the denial of employment of Smt.Ramani Amma, Smt.Geetha.G. and Geetha.R, who were employees of Western India Cashew Company, was justifiable and if it was found otherwise, the relief for which they were entitled to."

3. The case of the Union, which espoused the cause of the workers, was that the delinquent workers were employed by the management in their packing centre at Puthentheruvu, Karunagappally. Since 26.10.2012 was a public holiday owing to Bakrid, the factory was closed. On 27.10.2012, when the workers reached the factory, they were denied employment by the Management. The Union raised an industrial dispute and the matter reached the District Labour Officer, who convened a conference. In the meantime, a WP(C) No.12490/2018 3 show cause notice was issued to the workers and consequently on 2.11.2012, the workers were suspended from service pending enquiry. An enquiry officer was appointed who proceeded with the enquiry and submitted a report with the finding that the workers were guilty of all charges. Banking on the said report, the workers were dismissed from service with retrospective effect. According to the Union, the enquiry which was conducted was a farce and is therefore vitiated. The principles of natural justice were violated and the management failed to bring home the charge. They also contended that the punishment imposed was grossly disproportionate to the nature of charges levelled against the workers.

Archives, Room Use Only - TK144.F67 1846

The transmission of the optical components of the Bernina branch of the Aramis beamline at SwissFEL has been measured with an X-ray gas monitor from DESY and compared with a PSI gas detector upstream of the optical components. The transmission efficiencies of the Mo, Si and SiC mirror coatings of the Aramis beamline and the various other in-beam components were evaluated and compared with theoretical calculations, showing an agreement of 6% or better in all cases. The experiment has also shown the efficacy of the high-harmonic rejection mirrors at the Bernina branch of the Aramis beamline at SwissFEL, and characterized the transmission efficiency of the on-line spectrometer in the Aramis beamline. The theoretical transmission of the mirror coatings match the experimental data to within 7%. The accuracy of these measurements was checked against a radiative bolometer from a Japanese collaboration and found to agree to a level of 4% or better. Further comparisons with a diamond detector from a US-based inter-institute collaboration demonstrated a good agreement for the attenuator settings of the beamline.

This study presents the crystal structure of a thiol variant of the human mitochondrial branched-chain aminotransferase protein. Human branched-chain aminotransferase (hBCAT) catalyzes the transamination of the branched-chain amino acids leucine, valine and isoleucine and α-ketoglutarate to their respective α-keto acids and glutamate. hBCAT activity is regulated by a CXXC center located approximately 10 Å from the active site. This redox-active center facilitates recycling between the reduced and oxidized states, representing hBCAT in its active and inactive forms, respectively. Site-directed mutagenesis of the redox sensor (Cys315) results in a significant loss of activity, with no loss of activity reported on the mutation of the resolving cysteine (Cys318), which allows the reversible formation of a disulfide bond between Cys315 and Cys318. The crystal structure of the oxidized form of the C318A variant was used to better understand the contributions of the individual cysteines and their oxidation states. The structure reveals the modified CXXC center in a conformation similar to that in the oxidized wild type, supporting the notion that its regulatory mechanism depends on switching the Cys315 side chain between active and inactive conformations. Moreover, the structure reveals conformational differences in the N-terminal and inter-domain region that may correlate with the inactivated state of the CXXC center.

When songwriter Oscar Hammerstein penned the lyrics “fish gotta swim, birds gotta fly,” he clearly did not have the ratites in mind. Large flightless birds, the ratites include ostriches, emus, rheas and cassowaries, along with kiwis and several extinct species.

The post DNA evidence is rearranging the branches of the avian family tree appeared first on Smithsonian Insider.

A newly-discovered species of ant supports a controversial theory of species formation. The ant, known to live only under a single eucalyptus tree on the […]

The post Deadbeat ant species branched off as parasite inside its own colony appeared first on Smithsonian Insider.

38625 14th Avenue, Suite 100
North Branch, MN 55056
Thursday, May 28, 2020, 9am – 4pm

Every Thursday Residential Services, Inc (RSI) hosts walk-in interviews at our office in North Branch, hiring for the position of Direct Support Professional.

When: Thursdays from 9am-4pm
Where: 38625 14th Avenue, Suite 100


Qualifications:
-Must be 18 years of age (21 to work in child foster care settings)
-Must be able to pass a background check
Passionate about improving the lives of others

About the Job:
DSPs provide individualized services to people with disabilities and/or mental illness who are living in home settings. The people who receive services from RSI rely on their caregivers to provide a safe living environment and to help meet all of their physical, emotional, social, medical, spiritual, and recreational needs and wants. DSPs assist in a variety of day-to-day tasks based on the individual needs and goals of the people they are caring for, which could include medication administration, household duties, assistance with personal hygiene, and community activities such as shopping, concerts, going out to eat, movies, fitness, outdoor recreation, and more.

RSI is an Equal Opportunity Employer

Event type: Job and Career Fairs
Filter by Location: Greater Minnesota
Event Audience: For Job Seekers, For Veterans
Accommodation Request: 2187407621
CareerForce Sponsored Event: Other event
More info: www.rsi.jobs

38625 14th Avenue, Suite 100
North Branch, MN 55056
Thursday, May 21, 2020, 9am – 4pm

Every Thursday Residential Services, Inc (RSI) hosts walk-in interviews at our office in North Branch, hiring for the position of Direct Support Professional.

When: Thursdays from 9am-4pm
Where: 38625 14th Avenue, Suite 100


Qualifications:
-Must be 18 years of age (21 to work in child foster care settings)
-Must be able to pass a background check
Passionate about improving the lives of others

About the Job:
DSPs provide individualized services to people with disabilities and/or mental illness who are living in home settings. The people who receive services from RSI rely on their caregivers to provide a safe living environment and to help meet all of their physical, emotional, social, medical, spiritual, and recreational needs and wants. DSPs assist in a variety of day-to-day tasks based on the individual needs and goals of the people they are caring for, which could include medication administration, household duties, assistance with personal hygiene, and community activities such as shopping, concerts, going out to eat, movies, fitness, outdoor recreation, and more.

RSI is an Equal Opportunity Employer

Event type: Job and Career Fairs
Filter by Location: Greater Minnesota
Event Audience: For Job Seekers, For Veterans
Accommodation Request: 2187407621
CareerForce Sponsored Event: Other event
More info: www.rsi.jobs

38625 14th Avenue, Suite 100
North Branch, MN 55056
Thursday, May 14, 2020, 9am – 4pm

Every Thursday Residential Services, Inc (RSI) hosts walk-in interviews at our office in North Branch, hiring for the position of Direct Support Professional.

When: Thursdays from 9am-4pm
Where: 38625 14th Avenue, Suite 100


Qualifications:
-Must be 18 years of age (21 to work in child foster care settings)
-Must be able to pass a background check
Passionate about improving the lives of others

About the Job:
DSPs provide individualized services to people with disabilities and/or mental illness who are living in home settings. The people who receive services from RSI rely on their caregivers to provide a safe living environment and to help meet all of their physical, emotional, social, medical, spiritual, and recreational needs and wants. DSPs assist in a variety of day-to-day tasks based on the individual needs and goals of the people they are caring for, which could include medication administration, household duties, assistance with personal hygiene, and community activities such as shopping, concerts, going out to eat, movies, fitness, outdoor recreation, and more.

RSI is an Equal Opportunity Employer

Event type: Job and Career Fairs
Filter by Location: Greater Minnesota
Event Audience: For Job Seekers, For Veterans
Accommodation Request: 2187407621
CareerForce Sponsored Event: Other event
More info: www.rsi.jobs

The drab potoo bird uses its coloring to disguise itself as a tree limb.

High-tech water filters are wonderful. But what if you could go DIY, using just a piece of wood?

DARPA using biotechnology in an effort to boost the U.S.'s national defense.

In honor of Women's History Month, Enviva honors and highlight the achievements of 3 remarkable female foresters.

As the first working week of self-isolation comes to a close for many, Insurance Age content director Jonathan Swift looks at the stance brokers are taking in terms shutting up shop or keeping their branches open.

Forget everything you know about how the West was won ~ The Spirits have a story to tell.

4-Ever-in-My Heart is an enchanting of blend action, drama and the Lakota culture and as a bonus, readers can download free Native flute music by acclaimed musician, Randy McGinnis.

Readers declare Wind in the Grasses Dancing"Mesmerizing," "Exciting," "A Jewel"

Author Quentin H. Young's Mystic Visions: Black Elk's Great Vision Clarified is now available.

Saint Coleman's Men's Club event "Walk on Water Fishing Tournament" partners with Alsco to benefit the Special Olympics of Broward County

Donation provides food to needy individuals, children and elderly in Southern Nevada