The compounds 2',3',4',6'-tetra-O-acetyl-β-d-gluco­pyranosyl N'-cyano-N-phenyl­carbamimido­thio­ate (C22H25N3O9S, 5a), 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-phenyl­carbamimido­thio­ate, (C22H25N3O9S, 5b), 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-methyl­carbamimido­thio­ate (C17H23N3O9S, 5c), and 2',3',4',6'-tetra-O-acetyl-β-d-galacto­pyranosyl N'-cyano-N-p-tolyl­carbamimido­thio­ate (C23H27N3O9S, 5d) all crystallize in P212121 with Z = 4. For all four structures, the configuration across the central (formal) C=N(CN) double bond of the carbamimido­thio­ate group is Z. The torsion angles C5—O1—C1—S (standard sugar numbering) are all close to 180°, confirming the β position of the substituent. Compound 5b involves an intra­molecular hydrogen bond N—H⋯O1; in 5c this contact is the weaker branch of a three-centre inter­action, whereas in 5a and 5d the H⋯O distances are much longer and do not represent significant inter­actions. The C—N bond lengths at the central carbon atom of the carbamimido­thio­ate group are almost equal. All C—O—C=O torsion angles of the acetyl groups correspond to a synperiplanar geometry, but otherwise all four mol­ecules display a high degree of conformational flexibility, with many widely differing torsion angles for equivalent groups. In the crystal packing, 5a, 5c and 5d form layer structures involving the classical hydrogen bond N—H⋯Ncyano and a variety of ‘weak’ hydrogen bonds C—H⋯O or C—H⋯S. The packing of 5b is almost featureless and involves a large number of borderline ‘weak’ hydrogen bonds. In an appendix, a potted history of wavelength preferences for structure determination is presented and it is recommended that, even for small organic crystals in non-centrosymmetric space groups, the use of Mo radiation should be considered.

The mol­ecular structure of the tripodal carbamoyl­methyl­phosphine oxide compound diethyl {[(5-[2-(di­eth­oxy­phosphor­yl)acetamido]-3-{2-[2-(di­eth­oxy­phos­phor­yl)acetamido]­eth­yl}pent­yl)carbamo­yl]meth­yl}phospho­nate, C25H52N3O12P3, features six intra­molecular hydrogen-bonding inter­actions. The phospho­nate groups have key bond lengths ranging from 1.4696 (12) to 1.4729 (12) Å (P=O), 1.5681 (11) to 1.5811 (12) Å (P—O) and 1.7881 (16) to 1.7936 (16) Å (P—C). Each amide group adopts a nearly perfect trans geometry, and the geometry around each phophorus atom resembles a slightly distorted tetra­hedron.

A demonstrator holds a sign in support of the Affordable Care Act in front of the U.S. Supreme Court last November. On Thursday, the justices did just that.; Credit: Alex Brandon/AP

The U.S. Supreme Court upheld the Affordable Care Act for the third time on Thursday, leaving in place the broad provisions of the law enacted by Congress in 201o. The vote was 7 to 2.

The opinion was authored by Justice Stephen Breyer who was joined by Chief Justice John Roberts and Justices Clarence Thomas, Sonia Sotomayor, Elena Kagan, Brett Kavanaugh and Amy Coney Barrett. Justices Samuel Alito and Neil Gorsuch dissented.

The decision threw out the challenge to the law on the grounds that Texas and other objecting GOP-dominated states were not required to pay anything under the mandate provision and thus had no standing to bring the challenge to court.

"To have standing, a plaintiff must 'allege personal injury fairly traceable to the defendant's allegedly unlawful conduct and likely to be redressed by the requested relief,' " the majority wrote. "No plaintiff has shown such an injury 'fairly traceable' to the 'allegedly unlawful conduct' challenged here."

The mandate, the most controversial provision of the law, required that people either buy health insurance or pay a penalty. In 2012, it was upheld by a 5-4 vote, with Chief Justice John Roberts casting the decisive fifth vote, on the grounds that the penalty fell within the taxing power of Congress.

In 2017, Congress got rid of the penalty after the Congressional Budget Office concluded that the law would continue to function effectively without it. That prompted the challengers to go back to court, contending that because the penalty had been zeroed out, it was no longer a tax or a mandate. What's more, they contended, because the mandate was so interwoven with the rest of the ACA, the whole law must be struck down.

Over 31 million Americans have access health insurance through the ACA — a record high since the law's inception, the White House said last week. In addition, the Urban Institute reported in May that ACA premiums have gone down each of the last three years.

Many of the provisions of the ACA are now taken for granted. Up to 135 million people are covered by the ban on discrimination against those with preexisting conditions.

Young adults are now permitted to stay on their parents' insurance until age 26; copays are not permitted for preventive care; and insurance companies can no longer put lifetime caps on benefits, are required to spend 80% of premiums on medical coverage and are barred from discrimination based on factors like gender.

In addition, Medicaid coverage was greatly expanded after all but a dozen states took advantage of the ACA to expand federally subsidized coverage under the program. Among those who have benefited are many who lost their health insurance when they lost their jobs in the COVID-19 pandemic.

This content is from Southern California Public Radio. View the original story at SCPR.org.

President Barack Obama reiterated his strong support for science and technology today in a speech to members of the National Academy of Sciences at its 150th annual meeting.

Today President Obama signed a Presidential Memorandum to address climate change and national security. The National Academies of Sciences, Engineering, and Medicine look forward to taking the lead in engaging the academic community in efforts to guide this initiative, and are well-positioned to tap the broad, multidisciplinary expertise of researchers across the nation.

The thaw-and-eat sandwich brand has grown from a $12 million property to about $800 million in annual sales, according to the company.

Hiller announced a five-year partnership with The University of Alabama’s Athletic Department and Crimson Tide Sports Marketing.

BRAVE® Fishin' for the Women

Award-winning writer Clark Hilton debuts a spellbinding science fiction novel "BAMBOO: A Post-Apocalyptic Odyssey," available now to buy online.

Books Illuminated is proud to make available to school libraries and public institutions the hardbound version of their popular climate fiction, "BAMBOO: A Post-Apocalyptic Odyssey."

"Even as a cataract surgeon with more than 30 years of experience, my ability to direct the controlled laser precision to further improve clinical results is amazing," summarized Dr. Michelson.

Local independent insurance group has expanded coverage all over the State of Alabama and Tennessee

Mr. William L. Bamford is recognized for his expert leadership of Decades Construction & Facilities Group.

Shweta S. Rao, BAMS, PGDCR, MPH, CHW channels years of expertise into her work with Sewa International

Press Release

Dr. Harpal Bambah Sodhi, PhD, recognized as an artist and educator with over five decades of experience

Successful dog trainer Dale Buchanan has been awarded the 2023 Best Dog Trainer in Huntsville, AL, from Quality Business Awards.

Successful dog trainer Dale Buchanan now offers Therapy Dog Training in Huntsville, AL.

Successful dog trainer Dale Buchanan has been voted the 2024 Best Pros In Town in Huntsville, AL.

In a pre-empt, the publisher has inked a six-figure, two-book deal for the speculative climate fiction BAMBOO series.

Poet and photographer Hodge and his service dog Mae will join 51 veteran gold medalists in May to showcase their creative talent.

Learn how to avoid missing out on $1000s in Tax credits and richer benefits.

President Barack Obama The White House Today is Earth Day — the last one I’ll celebrate as President. Looking back over the past seven years, I’m hopeful that the work we’ve done will allow my daughters and all of our … Continue reading →

Note: There is swearing in this episode.

In 2017, The University of Minnesota asked comedian Maria Bamford to give their commencement speech. But the University may not have known what it was in for. In her speech, Bamford told the crowd of graduates how much the university offered to pay her (nothing), her counteroffer ($20,000), and the amount they settled on ($10,000), which (after taxes and fees, etc.) she gave away to students in the audience to pay down their student loans.

Maria Bamford is a big believer in full disclosure of her finances, a philosophy she's adopted after decades in a Debtors Anonymous support group. In meetings, she learned important financial tips and tricks to go from thousands of dollars in debt to her current net worth of $3.5 million (a number which, true to her philosophy, she will share with anyone).

She spoke with us about her financial issues, how she recovered, and why she believes in total financial transparency, even when it makes her look kinda bad.

Disclaimer: Planet Money is not qualified or certified to give financial advice. And Maria is not a spokesperson for Debtors Anonymous in any way.

This show was hosted by Kenny Malone and Mary Childs. It was produced by Emma Peaslee, edited by Jess Jiang, fact-checked by Sierra Juarez, and engineered by Neisha Heinis. Alex Goldmark is Planet Money's executive producer.

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In this hour, a professional impersonator gets an unusual gig, a journalist is befuddled by the facts, and a brother sister duo who really love baseball. This episode is hosted by Moth Senior Director Jenifer Hixson. The Moth Radio Hour is produced by The Moth and Jay Allison of Atlantic Public Media.

Storytellers:

Obama impersonator Dion Flynn gets an unlikely gig.

Carole Radziwill is gifted a watch that belonged to Jackie Kennedy.

Michaela Murphy takes her little brother on a cross-country adventure to see an All-Star Game.

Podcast: 866

The President announced new steps with the private sector to strengthen the manufacturing sector, boost advanced manufacturing, and attract the good paying jobs that a growing middle class requires.

The President Barack Obama Lithograph by Thomas Blackshear II is a(n) Limited Edition. The Edition is Limited to Limited Edition of 6000 pcs

Manufacturing

La marca hermana de Volvo presume de "diseño escandinavo", con unos coches eléctricos muy bien terminados y a los que no le falta ningún detalle de equipamiento. Claro que este 3 pasa de los 90.000 euros en su versión más barata. Leer

Nuestra toma de contacto se centra en la versión M50, con casi 400 CV de potencia y un precio mínimo de 89.000 euros. Leer

Por ahora se pone a la venta con las versiones tope de gama, con 150 CV, más de 400 km de alcance y 31.584 euros de precio mínimo. En 2025, llegarán variantes más baratas y menos prestacionales Leer

Los egipcios han luchado valientemente, han echado a Mubarak y le han dado el poder a los militares. Pero resulta que el ejército egipcio está bastante controlado por USA, ya que fueron ellos los que lo financiaron y lo entrenaron [...] En América Latina y otros puntos del mundo, darle más poder un cuerpo militar que se apoya en USA habría significado un tremendo paso atrás. 

El nuevo botón de control de cámara es sin duda la estrella pero las mejoras fotográficas llegan con los nuevos estilos que es posible aplicar a las imágenes Leer

Pamela Falk, CBS News Foreign Affairs Analyst, discusses the foreign policy agenda of the NATO summit in Wales

Location: Electronic Resource- 

Undocumented immigrants brought to the U.S. as kids, who have legal status as DACA recipients, can buy subsidized health plans through Obamacare starting Nov. 1. But 18 states are suing to stop it.

Former President Barack Obama encouraged coders to join the Biden administration's artificial intelligence team.

The former president and his wife join the likes of Steven Spielberg, Kate Capshaw, Bruce Springsteen and Patti Scialfa who gather at Hanks' $26 million Pacific Palisades manse.

Andy Street joins expert panel for COVID-19 vaccine webinar.

Does anyone know what those green lapel pins are that about a third of Obama's staffers seem to be wearing in the photos here? (via)

Hora 20 retransmite la entrevista realizada por Javier Moreno, director de El País al expresidente de Estados Unidos, Barack Obama.

El director del diario El País contó que entrevista con Barack Obama fue un encuentro serio y que denota una realidad preocupante.

Updated at 4:45 a.m. ET on Wednesday Jeff Sessions has lost a bid to regain his old Alabama U.S. Senate after falling from grace as President Trump's attorney general. Sessions had been hoping for redemption after enduring months of relentless ridicule from Trump that eventually led to his resignation as the country's top lawyer. But it was not to be. Instead, Sessions conceded defeat to former Auburn University football coach Tommy Tuberville, a political neophyte, who handily beat him in the state's runoff election for the Republican nomination for U.S. Senate. "I leave elected office with my integrity intact," Sessions told reporters. "I hold my head high." Tuberville, 65, who was endorsed by the president in the GOP matchup — edged ahead of Sessions in Alabama's state primary in March but failed to secure a majority of the vote, setting up Tuesday's runoff. Tuberville will now face Democratic incumbent Sen. Doug Jones in November. As the race was called late Tuesday, Trump was

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