cl Synthesis of fluorescent 5-heteroarylpyrimidine-containing oligonucleotides via post-synthetic trifluoromethyl conversion By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00402G, PaperYuta Ito, Hisato Tanaka, Ayana Murakami, Yasufumi Fuchi, Yoshiyuki Hari5-(Benzimidazol-2-yl)- and 5-(benzothiazol-2-yl)-pyrimidine bases-modified oligonucleotides were prepared by post-synthetic trifluoromethyl conversion and their fluorescence properties were measured.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Synthesis of Asp-based lactam cyclic peptides using an amide-bonded diaminodiacid to prevent aspartimide formation By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00472H, CommunicationWen-Jie Li, Jun-You Chen, Hui-Xia Zhu, Yi-Ming Li, Yang XuA diaminodiacid (DADA) containing an amide bond can be used in Fmoc solid-phase peptide synthesis (SPPS) of an Asp-based lactam cyclic peptide with no aspartimide formation.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Catalyst- and base-free visible light-enabled radical relay trihalomethylation/functional group-migration/carbonylation with CX3SO2Cl By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00292J, PaperJinkai Hu, Chenglei Yang, Xiaotao Qin, Hui Liu, Tongtong Ma, Ao-tong Shi, Qing-Long Lv, Xingman Liu, Jinhui Yang, Dianjun LiA visible light-enabled photocatalyst-free radical trihalomethylation/cyano (or benzo[d]thiazol-2-yl) 1,4-migration/carbonylation reaction of 2-hydroxy-2-hex-5-enenitrile (or (benzo[d]thiazol-2-yl)-pent-4-enol) with CX3SO2Cl (X = F, Cl) is reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Stereoselective Synthesis of gem-Dihalopiperidines via Halo-Aza-Prins Cyclization Reaction: Access to Piperidin-4-ones and Pyridines By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00338A, PaperAnil Kumar Saikia, Surjya Kumar Bora, Subhamoy Biswas, Bipin Kumar BeheraAn efficient methodology for the synthesis of 4,4-dihalopiperidine derivatives has been developed from N-(3-halobut-3-en-1-yl)-4-methylbenzenesulfonamide and aldehyde catalyzed by In(OTf)3 in excellent yields. The reaction involves an initial formation of six...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Recent advances in spirocyclization of maleimides via transition-metal catalyzed C–H activation By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2916-2947DOI: 10.1039/D3OB01904G, Review ArticleSwadhin Swaraj Acharya, Sagarika Patra, Rojalini Maharana, Manaswini Dash, Liza Mama Barad, Bibhuti Bhusan ParidaIn recent years, the maleimide scaffold has received a great deal of attention in C–H activation.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl 2-Azabicyclo[3.2.1]octane scaffold: synthesis and applications By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2902-2915DOI: 10.1039/D4OB00199K, Review Article Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Mariana Crespo Monteiro, João Rafael Vale, Filipa SiopaThis review focuses on the preparation and applications in total synthesis of 2-azabicyclo[3.2.1]octane structures, a class of natural and synthetic compounds with a range of biological activities.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Not exclusively the activity, but the sweet spot: a dehydrogenase point mutation synergistically boosts activity, substrate tolerance, thermal stability and yield By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3009-3018DOI: 10.1039/D4OB00211C, PaperYu-Ke Cen, Lin Zhang, Yue Jiang, Xiang-Fu Meng, Yuan Li, Chao Xiang, Ya-Ping Xue, Yu-Guo ZhengA single-point mutation of 7α-HSDH achieved the highest activity and synergistically improved substrate tolerance, thermal stability, cofactor affinity, and conversion rate.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Selective synthesis of an elusive C-functional bis-cyclam and study of its inhibition of the CXCR4 chemokine receptor By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3059-3067DOI: 10.1039/D3OB02050A, PaperMarie M. Le Roy, Sandra Claes, Nathalie Saffon-Merceron, Dominique Schols, Thibault Troadec, Raphaël TripierA rare example of C,C'-linked bis-cyclam has been synthesized with controlled manner in mild conditions thanks to the “bis-aminal” tool, and its good CXCR4-recognition properties could be demonstated in vitro.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Expanding the scope of the successive ring expansion strategy for macrocycle and medium-sized ring synthesis: unreactive and reactive lactams By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2985-2991DOI: 10.1039/D4OB00285G, Paper Open Access This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence.Zhongzhen Yang, Marion Arnoux, Damien Hazelard, Owen R. Hughes, Joe Nabarro, Adrian C. Whitwood, Martin A. Fascione, Christopher D. Spicer, Philippe Compain, William P. UnsworthNew Successive Ring Expansion (SuRE) protocols are described for use on unreactive lactams, as well as iminosugar derived lactams.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl A phosphamide nucleotide analog: a substrate for polymerase synthesis of DNA By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2963-2967DOI: 10.1039/D4OB00089G, CommunicationJiong Meng, Qiaqia Guo, Xiaona Zhai, Song Yang, Shuai Wang, Pengcheng Wang, Debin JiA phosphamide nucleotide analog (dNTPγNH2) exhibited higher stability than dNTPs and can be recognized by DNA polymerases in PCR.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Synthesis of alkynyl sulfides via base-promoted nucleophilic ring-opening of α-bromostyrene sulfonium salt By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,2953-2957DOI: 10.1039/D4OB00203B, CommunicationJunqi Zhou, Ziyu Wang, Hanmiao Xu, Mengke Su, Jian WenAn effective method for synthesizing various alkynyl sulfides has been developed using tetramethylene sulfoxide as a sulfur source through base-promoted nucleophilic ring-opening reactions.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Identification and quantification of local antiaromaticity in polycyclic aromatic hydrocarbons (PAHs) based on the magnetic criterion By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3035-3044DOI: 10.1039/D4OB00114A, Paper Open Access This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.Erich Kleinpeter, Andreas KochThe ring current effect of entirely and partly (anti)aromatic PCHs are calculated and employed to visualize, qualify and quantify existing (anti)aromaticity, especially to decide unequivocally between PAHs and PAAHs.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Selective enhancement of (6–4) photoproduct formation in dithymine dinucleotides driven by specific sugar puckering By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, 22,3025-3034DOI: 10.1039/D4OB00279B, PaperJouda Jakhlal, Clément Denhez, Stéphanie Coantic-Castex, Agathe Martinez, Dominique Harakat, Thierry Douki, Dominique Guillaume, Pascale ClivioEvidence is presented that (6–4) photoproduct formation between two thymine residues in dinucleotide analogues is significantly and specifically enhanced when the 5''- and 3''-end sugar puckering are mainly north and south, respectively.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Charge-transfer inclusion complex formation of the tropylium cation with prism[6]arenes By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00423J, CommunicationGuojiao Zhang, Channi Cheng, Zhengxiang Li, Dezhi Zhao, Chengyou HanWe report that charge-transfer (CT) inclusion complexes were formed between prism[6]arenes and tropylium cation. Additionally, the CT complex showed Cl−/Ag+ responsiveness which can be easily monitored by the naked eye.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl BBr3-mediated dearomative spirocyclization of biaryl ynones: facile access to spiro[5.5]dienones By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00274A, CommunicationGaurav Jaiswal, Subhas Chandra PanBBr3 mediated dearomative spirocyclization of biaryl ynones has been reported for the direct synthesis of spiro[5.5]dienones with a tri-substituted double bond.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl 3-Halo-5,6-dihydro-4H-1,2-oxazine N-oxides as synthetic equivalents of unsaturated nitrile oxides in the [3 + 2]-cycloaddition with arynes: synthesis of substituted 3-vinyl-1,2-benzisoxazoles By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00391H, CommunicationAlexander A. Lukoyanov, Svetlana A. Aksenova, Andrey A. Tabolin, Alexey Yu. Sukhorukov3-Halo-1,2-oxazine N-oxide derivatives act as surrogates of vinyl nitrile oxides in tandem [3 + 2]-cycloaddition/[3 + 2]-cyclofragmentation with arynes leading to benzisoxazoles.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl Cu(OTf)2/HFIP catalyzed regioselective cycloisomerization of indole-C3-functionalized alkynols to carbazoles By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00421C, CommunicationSrinivasarao Yaragorla, Tabassum Khan, Sayonika ChakrobortyWe report here a simple and atom economic cycloisomerization reaction of indole-tethered alkynols for constructing diverse carbazoles via 1,2-alkly migration using Cu(OTf)2/HFIP as the excellent promoter system.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl An FeCl3-catalyzed three-component reaction for the synthesis of β-(1,2,3-triazolyl)-ketones using DMF as a one-carbon source By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Advance ArticleDOI: 10.1039/D4OB00207E, CommunicationRuilin Fang, Lei Zheng, Xuyang Chen, Can Wang, Yunfeng ChenFeCl3-catalyzed oxidative condensation of NH-1,2,3-triazoles and aryl methyl ketones and DMF has been reported.To cite this article before page numbers are assigned, use the DOI form of citation above.The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl A Highly Diastereoselective One-Pot Ugi/Radical Spirocyclization/Aza-Michael Addition Sequence By pubs.rsc.org Published On :: Org. Biomol. Chem., 2024, Accepted ManuscriptDOI: 10.1039/D4OB00610K, CommunicationChandra Volla, Salman Khan, Abhradeep Chatterjee, Akshay Murali NairWe hereby report a highly diastereoselective synthesis of chalcogenated azaspirotricycles via a one-pot Ugi/spirocyclization/ aza-Michael addition sequence. The reaction proceeded via a key visible light mediated spirocyclization step under mild,...The content of this RSS Feed (c) The Royal Society of Chemistry Full Article
cl ‘The challenge was in getting the aircraft’s custom clearance’ By www.thehindubusinessline.com Published On :: Sun, 22 Aug 2021 15:46:05 +0530 Private jet operator JetSetGo’s CEO Kanika Tekriwal describes the intricacies of directly importing and leasing an aircraft Full Article Flight Plan
cl OpenAI’s Whisper transcription tool used in hospitals invents things no one ever said, researchers claim By www.thehindu.com Published On :: Mon, 28 Oct 2024 08:21:00 +0530 Whisper is a popular transcription tool powered by artificial intelligence, but it has a major flaw Full Article Technology
cl Bridging the gap in mental healthcare services: NGOs launch dementia clinics in Hyderabad’s slums By www.thehindu.com Published On :: Tue, 29 Oct 2024 00:15:10 +0530 India continues to grapple with a dearth of mental healthcare services, even as the number of persons with dementia is expected to rise over the next two decades Full Article Hyderabad
cl Understanding orphan drugs: what are they, how are they classified and what are their challenges in the Indian context By www.thehindu.com Published On :: Mon, 04 Nov 2024 12:28:54 +0530 While orphan drugs are crucial to treating rare, sometimes debilitating conditions, the high cost of their research and development is a major barrier to their development in India Full Article Health
cl EXCLUSIVE! Honey Irani: My Son Farhan Akhtar By www.rediff.com Published On :: Tue, 09 Jan 2024 15:43:35 +0530 'He was an extremely naughty child, always in trouble and creating trouble.''He wanted to fly a kite at night, and sometimes, bunk school.''When I insisted on sending him, we could get a call from school that he had fainted.' Full Article
cl 'Mission to abrogate Article 370 is...' By www.rediff.com Published On :: Wed, 06 Mar 2024 16:24:40 +0530 'I was emotional when the decision took place on August 5, 2019.''I made the film with clear intentions of projecting the truth.' Full Article
cl EXCLUSIVE! The Payal Kapadia Interview By www.rediff.com Published On :: Mon, 27 May 2024 11:22:33 +0530 'Hope is about being more accepting of each other, the kind of solidarity and friendship that even our families may not be able to give.' Full Article
cl Expert clinic director successfully implements half-hour scheduling system, boosting therapist productivity By www.dnaindia.com Published On :: Mon, 04 Nov 2024 09:24:00 GMT As word spread about the success of the half-hour schedule, some early adopters became curious after the clinic director and the team showcased the benefits. Full Article Technology
cl Shaping the Future of Web Apps: Full Stack Developer's Expertise in API Design and Cloud Deployment By www.dnaindia.com Published On :: Tue, 05 Nov 2024 12:45:12 GMT Naga Lalitha has become visible as someone who is changing the face of technology for industry verticals like supply chain and manufacturing. Full Article Technology
cl The class of Kadamb By www.thehindu.com Published On :: Thu, 20 Oct 2016 17:16:08 +0530 Celebrated choreographer Kumudini Lakhia and her students talk about give and take in art. Chitra Swaminathan records the interaction. Full Article Friday Review
cl Onion auction to remain closed indefinitely in Nashik wholesale markets to protest 40% duty on export: Traders By www.thehindu.com Published On :: Mon, 21 Aug 2023 19:02:29 +0530 Traders claimed the central government's decision to impose 40% duty on the export of onions till December 31, 2023 will adversely affect the onion growers and its export Full Article Agri-Business
cl To curb price rise, Centre tells traders, millers to declare rice stocks on government portal By www.thehindu.com Published On :: Fri, 02 Feb 2024 23:10:11 +0530 They have to declare stock position of paddy and rice every Friday Full Article India
cl Nuclear excitation by electron capture seen at long last By physicsworld.com Published On :: 2018-02-20T13:55:46Z Breakthrough could lead to new type of energy source Full Article
cl Japan’s SuperKEKB set for first particle collisions By physicsworld.com Published On :: 2018-02-21T14:45:12Z Revamped accelerator will soon be smashing electrons and positrons together Full Article
cl Return of the classic By www.thehindubusinessline.com Published On :: Wed, 24 Jan 2018 13:48:11 +0530 The Mercedes AMG Roadster is a fitting tribute to the old classic Benz W 198 Full Article Luxe
cl Ready, set, click! By www.thehindubusinessline.com Published On :: Sat, 02 Mar 2019 17:11:58 +0530 The best cameras in the market, and why Sony gets the top spot among the Nikons and Canons Full Article Luxe
cl Inside Le Locle’s watch factories By www.thehindubusinessline.com Published On :: Fri, 04 Oct 2019 16:30:34 +0530 A tour of the Ulysse Nardin manufacture factory highlights age-old techniques of enamelling perfected by watchmakers Full Article Luxe
cl LGBTQ+ educators in Catholic schools: embracing synodality, inclusion, and justice / Ish Ruiz. By darius.uleth.ca Published On :: Lanham, MD : Rowman and Littlefield, 2024. Full Article
cl Developing inclusive schools [electronic resource] : pathways to success / Mel Ainscow. By darius.uleth.ca Published On :: Abingdon, Oxon ; New York, NY : Routledge , 2024. Full Article
cl Equity and inclusion in higher education [electronic resource] : strategies for teaching / edited by Rita Kumar and Brenda Refaei. By darius.uleth.ca Published On :: Cincinnati : University of Cincinnati Press, 2021. Full Article
cl Chennai-based organisation invokes actors, celebrities to bring attention to climate change issues By www.thehindu.com Published On :: Mon, 19 Dec 2022 16:00:03 +0530 The organisation, Poovulagin Nanbargal, uses the birth dates and birth places of popular Tamil actors to highlight how climate change, such as increasing hot days, has affected the State over the decades Full Article Chennai
cl Uttar Pradesh declares The Kerala Story tax-free, CM Yogi to watch with entire cabinet By www.thehindu.com Published On :: Tue, 09 May 2023 10:44:48 +0530 Uttar Pradesh becomes the second State after Madhya Pradesh to make the controversial film tax-free Full Article Entertainment
cl ‘Spy’ movie review: A patchy attempt at a thriller with a story steeped in cliches By www.thehindu.com Published On :: Thu, 29 Jun 2023 17:09:42 +0530 The Nikhil Siddhartha starrer attempts to merge a personal story with secret files pertaining to Subhas Chandra Bose and the result is a listless thriller, thanks to several old tropes Full Article Movies
cl HP launches its first consumer PCs made with ‘recycled plastics’ By www.thehindubusinessline.com Published On :: Tue, 23 Feb 2021 14:22:21 +0530 The new Pavilion is powered by 11th Gen Intel Core processors with Intel Iris Xe graphics Full Article Computers & Laptops
cl Samsung launches six laptops in India, including Galaxy Book2 Pro 360, Galaxy Book2 Pro By www.thehindubusinessline.com Published On :: Sun, 03 Apr 2022 11:09:41 +0530 The Galaxy Book2 series includes the Galaxy Book2 Pro 360, Book2 Pro, Book2 and Book2 360. Full Article Computers & Laptops
cl Multi-cloud is the biggest bet we are making: Dell Co-COO By www.thehindubusinessline.com Published On :: Mon, 11 Jul 2022 11:47:24 +0530 Full Article Computers & Laptops
cl Democratic breakdown and the decline of the Russian military / Zoltan Barany. By encore.st-andrews.ac.uk Published On :: Princeton : Princeton University Press, [2007] Full Article
cl The worst accident in the world : Chernobyl, the end of the nuclear dream / Nigel Hawkes [and others] ; illustrations by Duncan Mil. By encore.st-andrews.ac.uk Published On :: London : Pan Books Ltd : William Heinemann Ltd, 1986. Full Article
cl Creating Belfast : technical education and the formation of a great industrial city, 1801-1921 / Professor Don McCloy. By encore.st-andrews.ac.uk Published On :: Dublin : Nonsuch, 2009. Full Article
cl Class A / Robert Muchamore. By encore.st-andrews.ac.uk Published On :: London : Hodder and Stoughton, 2015. Full Article
cl Oh, to be a painter! / Virginia Woolf ; introduced and selected by Claudia Tobin. By encore.st-andrews.ac.uk Published On :: New York, New York : David Zwirner Books, [2021] Full Article
