ise

White Matter Disease and Outcomes of Mechanical Thrombectomy for Acute Ischemic Stroke [INTERVENTIONAL]

BACKGROUND AND PURPOSE:

The increased severity of white matter disease is associated with worse outcomes and an increased rate of intracerebral hemorrhage in patients with ischemic stroke undergoing thrombolytic treatment. However, whether white matter disease is associated with outcomes in patients undergoing endovascular treatment remains unclear.

MATERIALS AND METHODS:

In this prespecified exploratory analysis of our prospective multi-institutional study that enrolled consecutive adult patients with anterior circulation ischemic stroke undergoing endovascular treatment from November 2017 to September 2018, we compared the following outcomes between patients with none-to-minimal (van Swieten score, 0–2) and moderate-to-severe (van Swieten score, 3–4) white matter disease using logistic regression: 90-day mRS 3–6, death, intracerebral hemorrhage, successful recanalization, and early neurologic recovery.

RESULTS:

Of the 485 patients enrolled in the Blood Pressure after Endovascular Stroke Therapy (BEST) study, 389 had white matter disease graded (50% women; median age, 68 years; range, 58–79 years). A van Swieten score of 3–4 (n = 74/389, 19%) was associated with a higher rate of 90-day mRS of 3–6 (45% versus 18%; adjusted OR, 2.73; 95% CI, 1.34–5.93; P = .008). Although the death rate was higher in patients with van Swieten scores of 3–4 (26% versus 15%), the adjusted likelihood was not significantly different (adjusted OR, 1.14; 95% CI, 0.56–2.26; P = .710). Ordered regression revealed a shift toward worse mRS scores with increasing van Swieten scores (adjusted common OR, 3.04; 95% CI, 1.93–4.84; P < .001). No associations between white matter disease severity and intracerebral hemorrhage, successful recanalization, and early neurologic recovery were observed.

CONCLUSIONS:

Moderate-to-severe white matter disease is associated with worse outcomes in patients undergoing endovascular treatment without a significant increase in hemorrhagic complications. Studies comparing patients with and without endovascular treatment are necessary to determine whether the benefit of endovascular treatment is attenuated with greater white matter disease.




ise

MR Thermometry in Cerebrovascular Disease: Physiologic Basis, Hemodynamic Dependence, and a New Frontier in Stroke Imaging [ADULT BRAIN]

SUMMARY:

The remarkable temperature sensitivity of the brain is widely recognized and has been studied for its role in the potentiation of ischemic and other neurologic injuries. Pyrexia frequently complicates large-vessel acute ischemic stroke and develops commonly in critically ill neurologic patients; the profound sensitivity of the brain even to minor intraischemic temperature changes, together with the discovery of brain-to-systemic as well as intracerebral temperature gradients, has thus compelled the exploration of cerebral thermoregulation and uncovered its immutable dependence on cerebral blood flow. A lack of pragmatic and noninvasive tools for spatially and temporally resolved brain thermometry has historically restricted empiric study of cerebral temperature homeostasis; however, MR thermometry (MRT) leveraging temperature-sensitive nuclear magnetic resonance phenomena is well-suited to bridging this long-standing gap. This review aims to introduce the reader to the following: 1) fundamental aspects of cerebral thermoregulation, 2) the physical basis of noninvasive MRT, and 3) the physiologic interdependence of cerebral temperature, perfusion, metabolism, and viability.




ise

Quản lý 100% giỏ hàng căn hộ Sunrise Riverside 10tr/th căn 2PN-12TR/th,căn 3PN -16TR/th.0982598959

Chuyên cho thuê căn hộ Sunrise Riverside - Novaland. - Căn hộ 55m2 - 2PN + 1WC. + Nội thất cơ bản: 9tr - 11 triệu/tháng. + Đầy đủ nội thất: 11.5tr - 13 triệu/tháng.- Căn hộ 70m2, 72m2 - 2PN + 2WC. + Nội thất cơ bản: 10tr - 12 triệu/tháng. + Đầy đủ nội thất: 12tr - 16 triệu/tháng....




ise

cho thuê shophouse sunrise riverside 50m2 hoàn thiện căn bản có máy lạnh âm trần 3.5hp, giá 15tr/th

cho thuê shophouse sunrise riverside 50m2, hoàn thiện có wc, máy lạnh âm trần 3.5hp, giá thuê bao rẻ nhất toàn khu 15tr/ tháng. tin thật 100%, nhanh còn, chậm hết ạ....




ise

Apartment for sale and for rent In Sunrise South Tan Hung Ward District 7 - 106 sqm- 4.55 Billion

Apartment for sale and for rent In Sunrise South Tan Hung Ward District 7 - Area: 106 sqm, beautiful new interior - Near Lotteria Edge, International school, etc. - Sale Price: 4.55 billion GOLDEN MOMENT FOR INVESTMENT DECISIONS Get and deposit for sale or for rent Real E...




ise

US millionaire advises millennials should buy home, not rent

Self-made millionaire David Bach says not buying a home is the single biggest mistake millennials (who were born between 1980 and 2000) are making.




ise

Sunrise City apartment for rent in District 7

Sunrise City apartment in District 7 for rentApartment area: 100m2 designed 2 bedrooms with full high-class furniture.Rental price is only 900$ / monthThe apartment is extremely clean and extremely beautiful ... 99.9% new. Korean style design. There are pool and gym room.Sunrise ...




ise

Be a wise tenant

Know your rights when you rent a house or apartment




ise

Chorus: Rise as One Announced for Xbox Series X, PS5, PS4, Xbox One, And PC

Publisher Deep Silver and developer Fishlabs have announced Chorus: Rise as One for the Xbox Series X, PlayStation 4, PlayStation 4, Xbox One, and Windows PC. It will launch in 2021.

View the announcement trailer below:

Here is an overview of the game:

Take control of Nara, once the Circle’s deadliest warrior, now their most wanted fugitive, on a quest to destroy the dark cult that created her. Unlock devastating weapons and mind-bending abilities in a true evolution of the space-combat shooter. Along with Forsaken, her sentient starfighter, explore ancient temples, engage in exhilarating zero-g combat, and venture beyond our waking reality.

Key Features:

  • Journey of Redemption – Lead Nara, an ace pilot facing her haunted past, and Forsaken, her sentient ship on a quest for redemption across the galaxy.
  • Venture Beyond the Void – Enter a dark new universe, teeming with mystery that balances the scale and spectacle of exploration with fast-paced action.
  • One Pilot, One Ship, One Living Weapon – Attain unique weapons. Unlock deadly abilities. Chain powers together to become the ultimate living weapon.

A life-long and avid gamer, William D'Angelo was first introduced to VGChartz in 2007. After years of supporting the site, he was brought on in 2010 as a junior analyst, working his way up to lead analyst in 2012. He has expanded his involvement in the gaming community by producing content on his own YouTube channel and Twitch channel dedicated to gaming Let's Plays and tutorials. You can contact the author at wdangelo@vgchartz.com or on Twitter @TrunksWD.

Full Article - https://www.vgchartz.com/article/443419/chorus-rise-as-one-announced-for-xbox-series-x-ps5-ps4-xbox-one-and-pc/




ise

How a flawed mentality led to Silicon Valley’s meteoric rise

In the memoir Uncanny Valley, Anna Wiener examines the collective hyperconfidence that has enabled the tech sector’s meteoric growth




ise

Surprise contender Honeywell enters the quantum computing race

Honeywell, the same company that might make your humidifier or home security system, is unveiling a powerful quantum computer that will be available to the public




ise

Gamifying hate: How alt-right extremists recruit and mobilise online

Julia Ebner infiltrated the hidden forums that extremists use. Her experiences lay bare how they hijack social media and video games to spread hate – and how to beat them




ise

Ban Cruises

In addition to being a hotbed for pandemics, the cruise industry is an ethical and ecological abomination.




ise

Sony’s New Noise-Cancelling Workout Earbuds Have the Best Sound You Can Buy

Sony has managed to best its top-of-the-line noise cancelling earbuds with a new, improved, and best of all, cheaper model.




ise

Zens Comes Closest to Delivering the Wireless Charger Apple AirPower Promised to Be

It delivers almost all the functionality Apple promised, with a steep Apple-like price tag to match.




ise

Sennheiser Momentum True Wireless 2: A Casual $500 In Australia

Sennheiser has just released its second generation of its noise cancelling earbuds in Australia - the Sennheiser Momentum True Wireless 2. Here's what we know about them and how much they cost. Spoiler alert - they ain't cheap. More »
    




ise

State pension age changed this week – this is when the next rise will occur



STATE pension age is continually being reviewed and altered by the government. The latest change occurred earlier this week.




ise

How Much AI Expertise Do Thought Leaders and Companies Really Have?

Consultancy firm Certified Artificial, which is offering to certify AI companies, has demonstrated its prowess by rating the expertise of Elon Musk and Henry Kissinger



  • robotics
  • robotics/artificial-intelligence

ise

PromisePay changes gear

Fast-growing Melbourne payments company PromisePay is ramping its growth plans in the global platform economy.




ise

Chorus: Rise as One release confirmed for PS5, Xbox Series X, PS4, Xbox



Chorus: Rise as One is a new space-combat shooter, revealed during Inside Xbox. Here's everything you need to know.




ise

RPGCast – Episode 344: “Vana’diel Disease”

Chris gets 100 fisted by a tarutaru. Alice finds a new pastime in countryside lifepod touring. Anna Marie pushes things to the limit. And Alex...




ise

RPGCast – Episode 349: “We Like That Noise In Japanese”

Chris has to finish writing this summary so he can start building his new PC. So….the folks talk about E3 and some stuff and amiibos...




ise

Nicola Sturgeon "considering" relaxation of lockdown exercise restrictions

First Minister Nicola Sturgeon has said the Scottish Government is looking into expanding the current guidance about exercise during the lockdown.




ise

Tiny devices promise new horizon for security screening and medical imaging

Miniature devices that could be developed into safe, high-resolution imaging technology, with uses such as helping doctors identify potentially deadly cancers and treat them early, have been created.




ise

Certain foods common in diets of US adults with inflammatory bowel disease

Foods, such as French fries, cheese, cookies, soda, and sports and energy drinks, are commonly found in the diets of United States adults with inflammatory bowel disease, according to a new study.




ise

Accumulation of gene mutations in chronic Graft-versus-host disease

Mutations in white blood cells can contribute to abnormal immune profile after hematopoietic stem cell transplantation.




ise

China to reform disease prevention system




ise

The rise of Netflix: an empire built on debt - podcast

Mark Lawson and Dan Milmo discuss the sustainability of the streaming service. Plus: Lara Spirit on why you should register to vote before Tuesday’s deadline

Netflix has risen from obscurity to be one of the most powerful media companies in the world with more than 150 million global subscribers. It has launched critically acclaimed hits such as House of Cards, The Crown and Unbelievable, as well as showcasing the back catalogues of popular television series. But as part of its rapid growth, the company has racked up huge debts.

Joining Anushka Asthana to discuss the long-term sustainability of Netflix are the TV critic Mark Lawson and the Guardian’s deputy business editor Dan Milmo.

Continue reading...




ise

Andy Serkis to read The Hobbit nonstop to raise money for the NHS

The actor, best known for playing Gollum in the Lord of the Rings and Hobbit films, will read the entire JRR Tolkien novel

Andy Serkis is to give a continuous, live reading of The Hobbit – lasting around 12 hours – in aid of charity. The actor, best known as Gollum in the Lord of the Rings and Hobbit films, will read the entire book from start to finish with no breaks.

Money raised from the performance will be split equally between NHS Charities Together and Best Beginnings.

Continue reading...




ise

Working Out at Home? Here’s the Smartest Exercise Gear You Can Use

From yoga apps to an intelligent jumprope




ise

After 160,000 accounts are compromised, Nintendo shuts down NNID logins

Nintendo today confirmed earlier reports of account breaches dating back over the past few weeks. The gaming giant issued an update (via Nintendo Japan) noting that around 160,000 Nintendo Accounts were impacted, which found multiple being used to purchase digital items without the owner’s consent. Along with the purchasing powers, the offending parties may have […]




ise

Guilded raises $7 million for its competitive gaming-focused chat app

Gaming platforms have earned serious clout with investors in recent years. Add in the VC excitement surrounding collaboration tools and it’s no surprised there’s interest in backing another gaming chat app. Guilded is creating a chat platform designed for competitive gaming and esports that focuses heavily on keeping gamers organized and connected with their teams. […]




ise

Pence spokeswoman, married to top Trump adviser, diagnosed with coronavirus

U.S. Vice President Mike Pence's press secretary, the wife of one of President Donald Trump's senior advisers, has tested positive for the coronavirus, raising alarm about the virus' potential spread within the White House's inner most circle.




ise

U.S. moves to drop case against Trump ex-adviser Flynn, who admitted lying to FBI

The U.S. Justice Department on Thursday abruptly asked a judge to drop criminal charges against Donald Trump's former national security adviser Michael Flynn following mounting pressure from the Republican president and his political allies on the right.




ise

Bilateral ties poised for even bigger take-off: Ruchi Ghanashyam




ise

Nepal raises objection over India inaugurating crucial link road passing through Lipulekh Pass




ise

UK science advisers expect coronavirus epidemic to peak within a month

The peak of the UK coronavirus epidemic now looks likely to arrive within the next month, according to analysis by the government’s science advisers




ise

Blood test shows promise for detecting the deadliest cancers early

A blood test developed and checked using blood samples from 4000 people can accurately detect more than 50 cancer types




ise

Diet and exercise will keep your brain young – depending on your genes

Following a healthy diet or exercising could impact how your brain ages, but the effects on cognitive skills later in life depend on specific gene variants that not everyone has




ise

End of one-child policy in China linked to rise in birth anomalies

Following China’s switch to a two-child policy, there has been a slight rise in congenital anomalies, perhaps because parents are older on average at conception




ise

Can breathing exercises really help protect you from covid-19?

Taking deep breaths and forcing a cough can help clear mucus, but these techniques are unlikely to prevent or treat coronavirus infections – here’s why




ise

Names of UK's coronavirus science advisers to be revealed

The membership of the UK's Scientific Advisory Group for Emergencies has so far been kept secret, but a list of names will soon be published, the UK's chief scientific adviser has said




ise

Transatlantic slavery introduced infectious diseases to the Americas

The remains of three slaves found in Mexico contain the earliest signs of the hepatitis B virus and yaws bacteria in the Americas, suggesting transatlantic slavery introduced these diseases




ise

Red light could be used to precisely target rheumatoid arthritis drugs

People with rheumatoid arthritis often take medicines that can have damaging side-effects, but a system that uses red light to deliver drugs exactly where they are needed could help




ise

Common herpes virus causes signs of Alzheimer's disease in brain cells

A study of brain cells in a dish adds to growing evidence that Alzheimer’s disease can be caused by herpes viruses, but antiviral treatment may help stop it





ise

Cannavaro sympathises with Van Dijk over Messi&#39;s Ballon d&#39;Or triumph

Defenders face an uphill struggle to win individual awards even before a ball has been kicked, according to Fabio Cannavaro.





ise

Sunrisers Hyderabad and Delhi Capitals Join Roses Are Red Challenge on Twitter, Post Hilarious Replies (Watch Video)

The Roses are Red Challenge has caught the internet and has become a fad now as the netizens are coming up with a hilarious line which rhyme with roses are red. It is the netizens who have started this trend amid lockdown and most of them are making their own versions of their poems. Most of them tickle your funny bone with the one-liners which have caught the attention of the Internet users.





ise

No gym, no problem: Italian gymnast improvises

With Italy's gym clubs and training facilities having fallen silent because of the coronavirus pandemic, 28-year-old Italian gymnast Marco Lodadio, silver medallist in the 2019 men's world artistic gymnastics championships, turned his garden into a fitness studio.

Without the sophisticated facilities that high-performance athletes normally count on, Lodadio modified a structure for a swing to train on rings.

Lodadio, whose parents had a gym where he began training when he was nine, has been stuck in lockdown for almost two months and this week has finally gotten back to his usual rigourous training regime as Italy begins gradually lifting its strict restrictions.





ise

Pogba and Fernandes can be &#39;amazing&#39; pairing with &#39;compromise&#39;, tips Neville

Gary Neville took to Twitter to answer questions around Paul Pogba and Bruno Fernandes, and Manchester United's future transfer policy.