The present invention relates to an in vitro method of diagnosing chronic myelomonocytic leukemia (CMML) in a subject, said method comprising the steps of: a) Detecting a monocyte population in a biological sample from said subject; b) Quantifying the CD14+/CD16− monocytes in said biological sample; c) Comparing the value of step b) to a reference value; and d) Diagnosing CMML based on said comparison. Preferably, said detecting step a) is performed by an exclusion gating strategy by flow cytometry.

Why can’t I get off during sex? Am I broken? I'm 20, straight, male, fit, and active. I masturbated prone — flat on my stomach — for years.…

Plus what should I do about my cast fetish? I'm a middle-aged gay man and I was recently diagnosed with sleep apnea. This is a disorder caused by the soft tissue in the throat collapsing during sleep.…

A gas turbine engine cooling system includes a gas turbine engine. The gas turbine engine includes a core engine, a cold sink, a core undercowl space, and a core cowl at least partially surrounding the core engine and defining a radially outer wall of the core undercowl space. The gas turbine engine cooling system includes an undercowl component positioned in the core undercowl space. The gas turbine engine cooling system also includes a heat pipe including a first end, a second end, and a conduit extending therebetween. The first end is thermally coupled to the undercowl component, and the second end is thermally coupled to the cold sink. The heat pipe facilitates transfer of a quantity of heat from the undercowl component to the cold sink.

The invention is in the field of engine building technology and may be used in space technology or aviation. Liquid-propellant rockets with Laval nozzles are well known, and they have the following insufficiencies: (1) high fuel consumption rates, which lead to increased dimensions and engine weight and boosters; (2) a relatively low combustion efficiency, because the low mass of the combustion products are emitted into the environment; (3) the large length of the de Laval nozzles with increased expansion ratios increase the dimensions and the engine weight; (4) use of high temperature rocket propellants—combustion products—in the camera and de Laval nozzle. These insufficiencies suppress using liquid-propellant rockets in space technology. The goal of the invention is decreasing the influence of these insufficiencies and obtaining an engine with improved efficiency. The goal is achieved with the creation of an engine with the subsonic discharge of combustion products and the creation of a simple nozzle construction.

News you don't want to miss for April 27:

1. Alameda County, along with five other Bay Area counties, announced the shelter in place order will be extended through the end of May, the San Francisco Chronicle reports.…

An apparatus includes a bathrobe having a vertically-extending placket extending along a front section of the bathrobe, and the vertically-extending placket is configured to allow the bathrobe to be put on or removed by a user. An elongated towel assembly is fixedly coupled to the bathrobe. The elongated towel assembly vertically hangs from and extends along any one of (A) a left-side vertically extending portion, (B) a right-side vertically extending portion, and (C) the left-side vertically extending portion and the right-side vertically extending portion of the bathrobe in such a way that the vertically-extending placket is available for usage by the user.

A footwear effects toning of the leg muscles. It includes two soles and a redress mechanism contained within each of the soles for redressing the positions of the soles, in order to adjust corresponding feet positions by toning the leg muscles. A shock absorbing pebble for use within the soles, includes an elastic membrane that deforms under pressure, and that defines two chambers that are connected by means of a gas permeable membrane. In a balanced position, the first chamber is filled with a mixture of gas along with fluid, and the second chamber is filled with gas. As an external force is applied to the membrane, gas molecules are forced into the second chamber, inflating it until equilibrium is achieved, thus dampening the external force.

POLICE have arrested a man for assaulting officers after he was told he was breaching the new coronavirus laws.

A MAN used homophobic slurs and threatened to "spread coronavirus" towards two Southampton police officers after he broke a window.

A SCHOOLBOY who was apart from his soldier dad for four months was stunned when he turned up out of the blue to pick him up from class - just in time for Christmas.

SEVENTEEN points separate the top five in Hampshire League County Division 1 – after the leading three sides crashed to defeat.

A FORMER world champion angler from Hampshire has won a national award after inspiring hundreds of youngsters to aim for glory.

Cue sports have enjoyed a long life – stretching back to their inception in the 15th century.

A MAN used homophobic slurs and threatened to "spread coronavirus" towards two Southampton police officers after he broke a window.

Video from the third night of the Rock Challenge 2015.

AT just three years old, little Ellie Maddox is one of the youngest participants in this Sunday's Race for Life.

CHRISTIAN AID Week, known for its red envelopes, collections and Big Brekkies, faced a big challenge this year, with all its traditional fund-raising events out of reach.

SHOLING, the 2014 FA Vase winners, have had a change of last-16 opponent in this year’s competition.

BLACKFIELD & LANGLEY say they are “broken” following the death of co-assistant manager Chris Farrell earlier today.

A HAMPSHIRE student is celebrating boxing success after giving a knockout performance in a national competition.

MARKS and Spencer stores across Hampshire could get the chop, according to figures from a leading retail analyst.

PLANNERS last night backed three major waterfront developments that are set to change the face of Southampton’s waterfront.

It all started as a bit of banter over a few pints of not very good ale.

The Dunlop MSA British Touring Car Championship (BTCC) is revving up to race into the fastest circuit in the country this weekend, as Thruxton in Hampshire prepares to play host to the UK’s premier motorsport series.

British Touring Car Championship drivers have been meeting fans and signing autographs at Westquay shopping centre, Southampton, ahead of this weekend's races at Thruxton.

Lacklustre Fareham slipped to a third England Hockey West Conference defeat in four matches when Bristol-based Clifton Robinson lifted themselves off the league basement with a 2-1 win, their first of the campaign.

IT was one of It was one of the most popular restaurants in Southampton.

CHRISTMAS is typically a time for cheer and celebration, but with the festive season approaching, many of us are starting to think about buying a tree.

In this short podcast, Graham Langford shares three quick tips on where you can use a 1-finger double-tap and hold (also known as a “long-press”) to be more efficient and productive on iOS.

1. Quickly access draft emails in the iOS Mail app with a “long-press” on the Compose button.
2. Quickly archive an email message with a “long-press” on the Delete button.
3. “Long-press” on the Delete key on the iOS keyboard to delete text faster - in some instances, the speed will increase incrementally with the amount of time you are holding the key.

Please post a comment to share your own tips on where “hidden” iOS features such as these make you more efficient and productive.

In this podcast, Thomas Domville shows us the Tank Battle Endless Gunner for iOS. Blow up or ram your way through wave after wave of enemies. Keep enough of fuel,armour and weapons to keep fighting on.

‎Tank Battle Endless Gunner on the App Store:
https://itunes.apple.com/tt/app/tank-battle-endless-gunner/id1458091689

The Stamford Symphony Orchestra is celebrating the genius of Beethoven with concerts on Saturday, Feb. 22 and Sunday, Feb. 23. Kate Remington talks with Music Director Designate Michael Stern about the works on the program: the Coriolan Overture , the Symphony No. 7 and the spectacular Violin Concerto with guest soloist Pamela Frank.

For their celebration of Beethoven's 250th birthday this year, the Fairfield County Chorale is performing one of his most famous works, the Emperor Piano Concerto with soloist Ilya Yakushev, and one of Beethoven's least known sacred works on Saturday, March 7 at the Norwalk Concert Hall. Kate Remington talks with Artistic Director David Rosenmeyer about what makes each of these two works so special.

At this year's (now postponed) Game Developers Conference, composer and sound designer Oda Tilset planned to present a session about how incorporating music created by a computer's Artificial Intelligence can be a useful tool. Oda tells me that AI-generated music is really helpful to generate ideas that a composer might not have thought of. For musicians and composers who are just getting their feet wet with computer-generated music software, Oda reccommends Noknok Audio , which is very flexible and easy to use. One of the murkier aspects of using AI to create music is who owns the end product. Oda has studied numerous user agreements for sharing audio and music, including SoundCloud and there's no clear answer. She says the best part of using AI is that it's like having a collaborator without those painful discssions about whose ideas are better! Episode tracklist All tracks composed by Oda's computer AI, modified in her digital audio workstation. Thanks to Dick Roberts for production

Google says most of its employees will likely be allowed to work remotely through the end of year. In a companywide meeting Thursday, Google CEO Sundar Pichai said employees who needed to work in the office would be allowed to return in June or July with enhanced safety measures in place. The rest would likely continue working from home, a Google spokesperson told NPR. Google had originally told employees work-from-home protocols would be in place at least through June 1. Facebook also said it would allow most of its employees to work remotely through the end of 2020, according to media reports. The company had previously announced it was canceling large events through June 2021 due to the coronavirus pandemic. Both companies began telling employees to stay home in March . Copyright 2020 NPR. To see more, visit https://www.npr.org.

NPR's education reporter talks about what graduating seniors are going through right now as the colleges are closed due to the pandemic and answers their questions.

The 'American Idol' alum serving as Queen frontman admits in a social media post that he and the 'Genie in a Bottle' hitmaker had tried to put together Summer tour before the COVID-19 lockdown.

The sixth studio album from the 'Stupid Love' singer was initially set to make its debur on April 10, but got delayed due to all that going on during the global coronavirus pandemic.

The sequel to Disney Family Singalong will be aired on Mother's Day with Jennifer Hudson and John Legend set to deliver their version of the 'Beauty and the Beast' theme.

As a longtime member of the band Foo Fighters, guitarist Chris Shiflett has seen his share of large venues. But the 48-year-old also enjoys the intimacy of a small bar. That's part of the reason Shiflett writes, records, and performs his own music. Hard Lessons, his second solo release, came out this summer.

Denise's eyebrow-raising action seems to have something to do with hookup rumors, which started to spark in late November 2019, involving her and former 'RHOBH' star Brandi Glanville.

Fans are given the chance to be eaten by a dinosaur in the upcoming 'Jurassic World' movie in exchange for donations to Covid-19 relief efforts amid the ongoing pandemic.

Denise's eyebrow-raising action seems to have something to do with hookup rumors, which started to spark in late November 2019, involving her and former 'RHOBH' star Brandi Glanville.

Vicky Cornell is facing accusation from her late husband's Soundgarden bandmates that she misused the money raised for charity for her personal purposes.

The so-called evidence collected by fan of the 'Shortie Like Mine' hitmaker's rumored drug abuse confirms an Instagram thot's claim that they were high on whippets during a drug-filled night out in April.

Taking fans along with him in a journey for an at-home trim by Katherine Schwarzenegger, the 'Guardians of the Galaxy' star shares a series of photos of his before and after looks.

Vicky Cornell has threatened to file a lawsuit in response to fraud allegations made against her by the three surviving members of her late husband's band.

The 'Fuller House' actress has lost her bid to get charges against her thrown out of the court in college admissions scandal that also sent fellow star Felicity Huffman to prison.

One of the former 'Empire' star's ex-lovers claims the actor owes him money and demands to be paid up, or he will release the three-minute footage of Jussie's sexual activities.

The 'Fuller House' actress has lost her bid to get charges against her thrown out of the court in college admissions scandal that also sent fellow star Felicity Huffman to prison.