The post CfP: Artificial Intelligence in Health Economics and Outcomes Research was curated by information for practice.

Musical Arts Center
Thursday, December 5, 2024, 7:30 – 9:30pm

Premiering just last year, Jacobs faculty choreographer Sasha Janes’ updated, stereotype- shattering version of this most popular ballet tells the story from the perspective of curious young Marie.

With the help of her Aunt Drosselmeyer, Marie learns to unleash the power of her imagination to take the audience with her on a wild adventure.

This fresh take on a fantastical story still features the incomparable score by Pyotr Ilyich Tchaikovsky.

“It was hands down the most magical version of The Nutcracker I have ever seen.” – Pointe Magazine 2023 Readers’ Choice

Cost: $25-$45
Ticket Web Link: operaballet.indiana.edu…
More info: operaballet.indiana.edu…

Buskirk-Chumley Theater
Saturday, November 30, 2024, 7 – 8:15pm

Bloomington’s own Nutcracker Ballet, danced by children for children and families! This slightly abridged version of the classic Nutcracker Ballet follows Clara through her adventures after receiving a magical gift from her Uncle Drosselmeyer. Watch Clara and the Nutcracker battle the evil Mouse King, dance through a swirl of snowflakes into the night and arrive in the magical Land of the Sweets presided over by the Sugar Plum Fairy and her sweet courtiers. Was it all a dream? Or was it the magic of Uncle Drosselmeyer and his gift?

Doors open 30 minutes before each performance.

Children 3 and younger that can sit on a parent's lap and don't need their own seat do not need a ticket.

Presenter: MotionArts Dance Academy
Contact: BCT Box Office, boxoffice@buskirkchumley.org
Cost: $15 -$20
Ticket Phone: 812-323-3020
Ticket Web Link: buskirkchumley.org…
Communities: Bloomington

Polling data suggests voters see opportunities to strengthen local environmental policies and change course on issues like oil by rail. by Taylor Griggs

Portland has long been known for a strong ethos of environmentalism among its population. But with the increasingly dire nature of the climate crisis, environmental issues are playing a central role in this year’s election. Amid changes to city government and heightened focus on the efficacy of Portland’s Clean Energy Community Benefits Fund (PCEF), residents and City Council candidates see an opportunity to shift gears on climate action. 

Survey data released earlier this week show Portland voters are especially concerned with how the future City Council will handle PCEF and the Zenith Energy oil terminal. Both topics have been controversial for current City Council members, most of whom are running to remain in City Hall. According to the survey results, Portland voters are more likely to support candidates who support strengthening PCEF and who oppose Zenith. 

The poll was conducted by progressive polling firm Data for Progress and Lead Locally, an organization that works to address climate change through local elections. It’s a point-in-time assessment of 579 likely Portland voters from October 4-9. Though this is a small fraction of Portland voters, the poll’s findings have been reflected in messaging from many City Council candidates throughout the campaign season. 

Take PCEF, a program approved by a 2018 ballot measure that collects a 1 percent tax on local big business sales and uses it to pay for local carbon-reduction projects, especially in historically disadvantaged communities. PCEF is overseen by Commissioner Carmen Rubio–a top candidate for mayor–in the Portland Bureau of Planning and Sustainability. 

Rubio directed major code changes at PCEF, transforming the program in alignment with the city’s climate goals, and has been commended for that work. But she’s been criticized for attempts to redirect PCEF money into struggling city programs. Fellow commissioner and mayoral candidate Rene Gonzalez also proposed funding unrelated programs, specifically public safety initiatives in his portfolio, with PCEF dollars. 

According to the voter survey, about 65 percent of likely Portland voters feel positively about PCEF, and would be more likely to vote for candidates who support strengthening the program. The majority of Council candidates, too, have expressed favorable views about PCEF. Most candidates, when asked in an Oregonian/OPB questionnaire, said they do not support putting PCEF back on the ballot, and want to make sure the program’s funds are only used for carbon-reduction projects. 

District 1 candidate Jamie Dunphy said he believes PCEF should be protected, and not used as a “slush fund or a general purpose sales tax.” District 2’s Marnie Glickman said “we are fortunate to have PCEF because climate resilience costs are rising,” and the program “shouldn’t be raided to fund other needs.” Similar sentiments were echoed among many of their peers.

A minority of candidates said they wanted to expand the uses for PCEF money by putting the measure back on the ballot. District 4 candidate Eli Arnold, for example, said he supports asking Portlanders to vote on PCEF again, and wants to “preserve the original projected size of the program and move the excess to the general fund.” Other candidates, such as Noah Ernst in District 1 and Melodie Beirwagen in District 3, said they’re concerned the tax has a negative impact on businesses in Portland. District 2 candidate Chris Olson had a different reason for wanting to put PCEF back on the ballot: He said he wants to increase the tax to 2 percent, ensuring "greater investment in renewable energy, green jobs, and economic justice." 

On the other side of the coin, the survey results show only 22 percent of Portlanders polled said they feel positively about Zenith Energy’s oil-by-rail terminal in the Northwest Industrial Area. Just under half of respondents said they have unfavorable views, with 32 percent saying they didn’t know enough to say. 

In 2022, the Portland Bureau of Development Services (BDS)—then overseen by Commissioner Dan Ryan, who is running for a seat in District 2—approved a land use permit for Zenith’s operations in Portland. The city previously denied the oil transport company a Land Use Compatibility Statement (LUCS), threatening Zenith’s future in the city. But city officials gave in after a lengthy legal battle, and a promise that Zenith would switch to renewable fuels. 

Environmental advocates doubted Zenith’s promise to switch to renewables, and said such a move wouldn’t protect Portlanders in the case of an earthquake and subsequent oil spill. When Rubio took over BDS in 2023, Zenith critics were hopeful for change, but the city maintained Zenith’s land use permit. Earlier this year, the Portland Elections Office found the oil transport company violated local lobbying rules while trying to get the permit approved, spending excessive time and money trying to court city officials, particularly Ryan and Rubio. 

More than two dozen people running for City Council have indicated they want the city to have a different relationship with Zenith. In an October 10 letter to the Oregon Department of Environmental Quality (DEQ), 27 candidates asked the agency to delay its decision making about Zenith’s Air Contaminant Discharge Permit. The candidates said given “the legitimate concerns of Portland organizations and community members,” they want the new City Council to have the opportunity to “review past city decisions, understand any potential enforcement liability, and weigh in during the public process.” 

Most of the candidates who signed the letter to the DEQ are from District 4, where Zenith’s facilities are located. Six of the candidates who signed hail from District 2, which would also be heavily impacted in the case of an oil spill in the Willamette River. The St. Johns neighborhood is directly across the river from Portland’s Critical Energy Infrastructure Hub, which houses the Zenith terminal. 

Candidates who signed the letter include Mitch Green, Chad Lykins, Eli Arnold, and Olivia Clark (District 4), Brian Conley, Tiffany Koyama Lane, and Angelita Morillo (District 3), Jonathan Tasini, Nat West, and Marnie Glickman (District 2), and Doug Clove and Peggy Sue Owens (District 1). 

“Portlanders do not want or deserve to have their safety put at risk by trains carrying dangerous liquid fuels, whether it is oil or so-called ‘renewable fuels,’” the letter reads. “Portland residents should be protected by their government and that’s what we hope to do on city council.” 

Portland environmental advocates say they want stronger climate leadership from the new City Council. In a press release about the polling results, Oregon Sierra Club Director Damon Motz-Storey said it’s evident that “Portlanders widely support environmental justice.” 

“Portlanders are tired of fossil fuels and the dangers they present to our communities, our climate, and the natural world, so we see right through the efforts to greenwash the Zenith crude oil terminal,” Motz-Storey said. “Climate leadership in Portland requires a commitment to environmental justice and taking on our biggest polluters.” 

Worried? Try putting your head deep into this garbage gossip can for a few minutes. by Elinor Jones

Hello, and welcome back to the Trash Report! Like many people with mental illness, my home is a reflection of what is happening with the ol' brain—when depression is in the driver's seat, my house gets messy; when anxiety is calling the shots, the palace is pristine. And friends, being ONE DAY away from yet ANOTHER "most crucial presidential election of our time," I am literally out of things to organize! There is no more dust. I'm ironing? Your girl is not okay. I love this column for an excuse to look at something besides another very frightening poll, so let's get to the trash!

As this election plummets to its final resting place, Kamala Harris has collected endorsements from such luminaries as Cardi B, Bad Bunny, Eminem, Jennifer Lopez, Harrison Ford, and most of the Avengers.

I do believe that, despite this, she will win https://t.co/cOU7ZeWAKa

— Chase Mitchell (@ChaseMit) November 3, 2024

The most recent celebrity to come out for Trump was none other than the the famously antisemitic Mel Gibson, who shared his support only after Trump's Nazi rally at Madison Square Garden, which goes to prove just how much of a Nazi rally that definitely was.  

On a recent episode of his podcast, Ted Danson apologized to Kelsey Grammer for carrying a grudge since they worked together on Cheers. Grammer graciously accepted the apology. But I am not graciously receiving this "gossip." What happened?! What was the argument about? Why do this on a podcast without giving us the tea? This is the same kind of bullshit "this is not who we are" 2016-era dignity that no longer is the vibe. We're petty now! Tell us who was mean! Danson went on to say "I feel like I missed out on the last 30 years of Kelsey Grammer." What celebrity planet was Ted Danson living on because I feel like the rest of us have seen far too much Kelsey Grammer in the past 30 years. Streaming services were basically invented to avoid reruns of Frasier. 

In much more interesting feuds, Martha Stewart alluded to one between her and fellow kitchen and lifestyle guru Ina Garten. Garten had claimed in her recent memoir that the women drifted apart after one of them moved to Connecticut. Stewart agrees that the rift had to do with a move, but it was Stewart moving into a federal prison. I would imagine it could feel complicated to be a public figure being friends with a felon, but I can guarantee that if one of my friends went to jail for a non-violent crime I wouldn't stop talking to them! I'd probably talk way too much to them, in fact. I just have so many questions. If Martha Stewart and I had been friends who fell out and she later reflected on it, she would be like "Elinor was there for me when I was in jail, but she was too there for me, and wouldn't leave me alone, and I was sick of talking about prison toilet wine, so that's when our feud started."

The long-awaited sequel to The Gladiator is coming out soon and I could not have less interest in going to see it! That is, until Pedro Pascal revealed that he and Paul Mescal kissed in one take of a fight scene, and that might be the take they used in the movie, and I guess I'm going to go see Gladiator 2 now. Have the Wicked PR folks considered floating a rumor that Cynthia Erivo and Ariana Grande kiss instead of hawking a green and pink version of every product on God's green earth? (And is there a pink earth? There probably will be soon!) 

At this point is there a category of merchandise that doesn’t have a Wicked tie-in? I’m half expecting my gynecologist to ask whether I want a pink or green speculum.

— Anika Chapin (@AnikaChapin) October 31, 2024

Channing Tatum and Zoe Kravitz have allegedly called off their engagement after three years together, and just days after Tatum finally ended his years-long divorce saga with ex Jenna Dewan. This makes me think that Zoe Kravitz for sure never thought that Tatum's divorce would ever be finalized when she said yes to that ring. Tatum has been spotted around New York City smoking cigarettes, but holding them in a way that makes me think he hasn't smoked before; starting smoking at 44 is hilarious, but also very hot and chic!

In other rebound choices, Gisele Bunchen revealed that she is pregnant with her third child, which will be her first since getting divorced from Tom Brady, and the first with her boyfriend, who is also her longtime Jiu-Jitsu instructor. Tom Brady is reacting to it like any normal 30-year-old woman and posting Fleetwood Mac lyrics to his Instagram which is the most I've ever liked him. 

Helen Mirren recently waxed poetically about tragic losses of beloved icons, specifically Kurt Cobain, and specifically that Kurt Cobain's early demise in the 90s meant that he never got to experience the magic that is a GPS system. Iconic music producer Quincy Jones passed away just yesterday. He would have seen GPS. Does Helen Mirren not think this is as sad of a loss, because at least he died with the immense satisfaction of having watched a little dot that represented his car being driven towards a destination, thus making it a full and worthwhile life? Helen Mirren has yet to comment. 

A Sam's Club in Maryland had to shut down last week due to a racoon breaking into their bakery. A statement from the store read "after attempts to locate the raccoon were unsuccessful, Sam's Club representatives were advised best practices to properly capture the animal." Which means that during the initial attempts to capture the animal, they had no idea what the best practices were, and it must have been so funny. Imagine that raccoon's surprise to learn that there is a way to eat croissants, pre-trash? Going back to garbage pastries after that has got to be a bummer. Anyway, as the kids say, "in da clerb we all fam," but the clerb is a Sam's Club. Sam's Clerb, as it were.

Okay, I just realized there's a bookshelf in my office that I haven't yet reorganized and if I don't do that right now it will make it so college-educated women in Michigan won't turn out in numbers, which makes a lot of sense when you think about it. I hope you get through the next few days okay. If you process stress by being around people, the Mercury is going to hold an election night party hosted by the more extroverted of us. Meanwhile, we indoor kids will be live-blogging as the night goes on, so check back here if that's something you can handle. Thank you for reading and for voting and for being cherished members of the dumpster pile. 

Nervously,

by Mercury Promotions

Look, nobody wants to be alone on election night—so why not spend it with the Mercury, two of our fave stand-up comics, and all your friends?

The Merc, along with our pals at Mississippi Studios are hosting an election night watch party TONIGHT, Tuesday, November 5, with special guest hosts, comedians Alex Falcone and Shain Brenden! Both are former winners of the Portland's Funniest Person contest as well as the Mercury's Geniuses of Comedy, and as the results roll in on the big screen, Falcone and Brenden will be entertaining everyone with hilarious comedy, spicy political takes, and welcoming some very special surprise guests as well!

Best of all, our election night party is FREE—so grab your friends and show up for a night of (hopefully) celebration for our first woman president and lots of laughs.

The Official Portland Mercury Election Watch Party—hosted by Alex Falcone and Shain Brenden

Tuesday, November 5, 6:30 pm

Mississippi Studios, 3939 N Mississippi

FREE (21+ only)

by Courtney Vaughn

The Mercury provides news and fun every single day—but your help is essential. If you believe Portland benefits from smart, local journalism and arts coverage, please consider making a small monthly contribution, because without you, there is no us. Thanks for your support!

Good morning and happy election day, Portland! Obviously, drop off that ballot if you haven't yet. If you need a replacement, the county elections office can help you. If you're not sure who to vote for, here's our handy dandy election guide, which even includes a cheat sheet for you to refer to when filling out your ballot. If you’re monitoring results, let us keep you company on our live election night blog, and if you need to commiserate with others, or share a joke and a drink to ease the stress, join us in person at Mississippi Studios tonight for our free election night party!

In Local News: 

• Speaking of the election, voter turnout so far in Multnomah County is a little low. The number of ballots returned by Monday hovered below 46 percent. In the last presidential election, more than 73 percent of Multnomah County ballots were returned the day before the election. Some have speculated that Portland’s new ranked choice voting system and the sheer number of City Council candidates is slowing voters down, or dissuading them from filling out their ballot. BUT, people were a lot less busy in 2020, and if RCV is the culprit, why is Clackamas County–which isn’t using ranked voting– also seeing just 50 percent turnout by Monday? Similarly, Washington County’s elections office reports only 47 percent of ballots were returned by Monday. Maybe voters procrastinated, or maybe they’re just waiting to drop off their ballots in broad daylight, when there’s less likelihood of a ballot box getting blown up by some nut job. 

Turnout in Multnomah County as of November 4, 1 days before the election.

Current: 46% of accepted ballots (50% with returned ballots)
2020: 73%
2004-2020 average: 65%
2004-2016 average: 63% pic.twitter.com/xVyPxKjebo

— John Horvick (@horvick) November 5, 2024

• In other local election news, a few buildings downtown have boarded up their windows in preparation for potential election night protests. Portland police have been hyping up the potential for election-related violence for months now, creating a bit of hysteria that’s got some major companies spooked. At least one online flier inviting anarchist protest has circulated, but it’s unrelated to any particular candidate or party and more directed at general disdain for the state of the country.

Both local and national law enforcement teams are on standby in Portland ahead of Election Day, but many businesses are taking matters into their own hands… boarding up their windows and doors. @fox12oregon pic.twitter.com/0kmbAWAIvb

— Mckenzie Richmond (@kenziestuvland) November 4, 2024

• Portland City Council seems primed to overturn the city’s agreement with Multnomah County on managing homelessness. As we reported a few weeks ago, City Commissioners Rene Gonzalez, Mingus Mapps and Dan Ryan have all signaled support for dissolving the intergovernmental agreement that lays out which functions each government agency handles, in an effort to collaborate and tag-team the region’s most critical issue. The three stooges allege Multnomah County hasn’t kept up its end of the bargain, and they’ve got professional shit stirrer and County Commissioner Sharon Meieran egging them on. This week, Portland City Council will vote on whether to end the agreement. Jessica Vega Pederson, chair of the county’s Board of Commissioners, has called out the plan to kill the agreement as short-sighted, misinformed, chickenshit, and harmful to unhoused Portlanders who need a bevy of resources and services.

Regional executive leaders are united supporting a collaborative approach to addressing homelessness, and pushing back on this political stunt that includes no plan.

“The three commissioners did not provide any alternative plan”https://t.co/KFIkThGrNo

— Jessica Vega Pederson (@jvegapederson) October 18, 2024

• Here’s a bright spot: Portland’s own Rose City Rollers took home a fifth world championship title over the weekend. The league’s all-star roller derby team, Wheels of Justice, overtook St. Louis’ Arch Rival Roller Derby in the final game of a three-day tournament at the Veterans Memorial Coliseum. Due to the international repercussions of the pandemic, this year’s Women’s Flat Track Derby Association Global Championships were the first since 2019. Keep your eyes peeled for more of our coverage. Rose City Rollers all-star team Wheels of Justice celebrates after a championship 
  win Sunday, Nov. 3.  courtney vaughn Gov. Tina Kotek (center) rallies the crowd Saturday, Nov. 2 at the 2024 Women's Flat
  Track Derby Association Global Championships. To the left, Kim "Rocket Mean" Stegeman (left) holds the championship Hydra trophy.   courtney vaughn

In National/World News:

• Attorneys for Elon Musk basically admitted that Musk’s election lottery scheme was more of a plot to boost the Republican party. When faced with charges of running an illegal election lottery, where he promised to pick a daily winner at random for a $1 million prize in an effort to get people registered to vote, attorneys said Musk never intended to use a lottery system to choose a winner. He instead planned to vet and select the right person to essentially be a cheerleader for Trump and the Republican party. Huh. Money can buy rocket ships and high-dollar attorneys, but it can’t buy intellect.

@lizzza

I’ll be with B

♬ original sound - Liza Koshy

• Quincy Jones, the musician and producer behind Michael Jackson’s Thriller who also worked with Frank Sinatra and was awarded 27 Grammys during his lifetime, died at 91. Jones died at home with family in Los Angeles. He was set to receive an honorary Academy Award later this month.

RIP to Quincy Jones. Do yourselves a solid and watch the documentary “Quincy” by his daughter, Rashida Jones. https://t.co/6nIE8VzPoz https://t.co/lOzgNCmFyZ

— GullahMuseumSC (@GullahSc) November 4, 2024

• Your black plastic spatula is slowly poisoning you. Recent reporting in The Atlantic reveals that many black plastic kitchen utensils are likely being made from recycled electronic waste, and leaching toxic chemicals into your food. The discovery was noted by a biochemist in 2018, who asserted that the high amount of flame retardants in black plastic products like spatulas signals the items were probably manufactured with recycled electronic parts used in computers and TVs. Because plastic is prone to leaching chemicals when it’s heated, researchers theorize it’s likely that black plastic cookware is releasing harmful compounds into cooking oil and hot foods. Might also be time to rethink all the plastic carryout containers used to store and reheat hot foods. ☣️????

• One last bit of election-related news, promise! ICYMI: Donald Trump pretended to blow a microphone during a campaign stop last week. Trump was pissed about the mic malfunctioning and his instinct was to mime a raunchy, suggestive movement with his hand and mouth. Keep this man away from children (and the White House). Hawk tuah!

@sbsnews_au

Donald Trump motions over an empty microphone stand after battling technical issues at a campaign rally.

♬ original sound - SBS News

This primary's days are numbered - and we've got what you need to get ready for Tuesday. Primary expert Dante Scala tells Brady why the first-in-the-nation vote can break your heart, yet keep you coming back for more. Plus, how New Hampshire is and isn't like the rest of the country. And a hero public radio reporter saves a First in the Nation landmark.

In 60 seconds, the commercial showcases a medley of horror film tropes, including a maniacal doll that presumably kills a group of young people whenever they play a catchy pop song.

Sunday's Super Bowl pits the New England Patriots against the Los Angeles Rams. LA's talent-packed offense gives New England's head coach Bill Belichick a tough choice on who to target.

Comedian Stef Dag shared her amazement when she found out that the TV show she was watching was actually filmed inside her apartment.

Up until Tuesday evening, 50 Cent held the distinction of throwing the worst first pitch in the history of all ceremony.

The price of bitcoin has hit a new high as investors bet that Donald Trump’s victory in the U.S. presidential election will be a boon for cryptocurrencies. 

One of the challenges to supporting persecuted Christians abroad is that many in the West don't realize just how much their brothers and sisters in Christ suffer for their faith, according to the head of a leading advocacy group.

One of the creators of a Christian nonprofit effort aimed at “better Christian politics” claims President-elect Donald Trump’s victory in the 2024 election is a “disaster” for the United States.

The president of Focus on the Family says he’s “encouraged” by Tuesday’s election results even as he acknowledged both victories and setbacks for the pro-life movement.

Award-winning author Ann Patchett - herself a seasoned literary interviewer - joined All Things Considered & The Bookshelf host Peter Biello to discuss her latest novel, The Dutch House , writing, bookselling, and how much she hates the Amazon Echo. The interview was part of our occasional series, In the Spotlight, produced in partnership with Gibson's Bookstore and the Capitol Center for the Arts. This interview was taped live at the Capitol Center for the Arts on October 2, 2019. Listen to the full interview below.

Many artists have had a difficult time during the pandemic, while they've also brought joy to other people who are struggling. For NHPR's series, The Show Goes On , we're talking with artists across New Hampshire about how they're making it through the pandemic. NHPR's Morning Edition host Rick Ganley spoke with Rhonda Besaw , a beadworker from Whitefield, about her work and what's she's learned this past year.

As I learned during a return visit this summer, the real draw in Plymouth is the centuries of maritime history. It goes well beyond the Mayflower, whose sailing from here 424 years ago on Sept. 16 was a historical fluke.

Overshadowed by artsy-fartsy Taos and Santa Fe, this is New Mexico’s most underrated city.

Sometimes suburbia is the destination. One such suburb is Irving, Texas. Once a bedroom community for Dallas, it has become a destination in its own right.

Once an outpost on the early frontier and later a port for steamers carrying tobacco and cotton, this town in northern Tennessee is today a hidden gem.

The upcoming UN conference on climate change in Glasgow was supposed to show the world the triumph of the United States and the European Union as trendsetters for everything "green". Unfortunately for them, Europe faced an unprecedented energy crisis, which called into question not only the competence of officials from Brussels, but also the feasibility of the strategy to switch to green energy as soon as possible. Russia, which did not want to dive into the whirlpool of decarbonization, found itself in a more advantageous position. Nevertheless, Moscow has something to show in Glasgow on the climate agenda. China, the United States and India altogether account for more CO2 emissions than all other countries combined. Russia accounts for less than five percent, but the anger of Western politicians and journalists, who propagate environmental slogans, is directed primarily at Russia. Such a biased attitude towards Russia is based on the laws of hybrid war: dirty propaganda should keep citizens in good shape, while raising the degree of hatred. EU demonises Russia and wants more Russian gas When European politicians accuse Russia of the gas crisis, their accusations fit into the anti-Russian agenda just as perfectly. Gazprom strictly fulfills all of its contracts, but this argumentation falls on deaf ears in the EU. For example, EU chief diplomat Josep Borrell saw "deep geopolitical roots" in the rise in energy prices. The head of the European Commission, Ursula von der Leyen, reproached the Russian gas monopoly for "not responding to higher demand" in Europe. Her compatriot from the Green party, claiming the portfolio of the Minister of Foreign Affairs of the Federal Republic of Germany, Annalena Baerbock, stated that Russia was "playing poker" in matters of gas supplies. She has an ironclad argument: after all, European gas storage facilities are comparatively empty.

A football player was killed when a flash of lightning struck him during a match between Juventud Bellavista and Familia Chocca in Peru. The incident occurred when the players were leaving the field due to bad weather. Thirty-nine-year-old defender Hugo de la Cruz Mesa died on the spot. Four other players were hospitalized, one of them remains in serious condition, Peruvian agency Andina said.

The Russian army is advancing from all sides near the settlemnt of Kurakhovo. "The pressure of the Russians on Kurakhovo has increased with new directions that threaten the logistics of the city. The Russian troops have deployed a huge number of resources in several areas of the front. They are actively storming the eastern part of Kurakhovo reaching into eastern outskirts of the city while trying to break through in the Ostrovsky area," Ukraine's DeepState website said. The Russian Armed Forces are trying to reach the Ilyinka-Berestki line in order to take control of the north of the city.

The Union of European Football Associations (UEFA) has launched a disciplinary investigation into the behavior of Turkish fans at the match of the second qualifying round of the Champions League between Fenerbahce (Turkey) and Dynamo (Kyiv). The football match, which took place on Wednesday in Istanbul, ended with a score of 2:1 in extra time in favor of the Ukrainian team. After the Ukrainian team scored the first goal, Turkish fans started chanting the name of Russian President Vladimir Putin. "In accordance with Article 31(4) of the Disciplinary Regulations, the UEFA Ethics and Disciplinary Inspector will conduct an investigation into the alleged misconduct of Fenerbahce fans during the Champions League second qualifying round second leg against Dynamo Kyiv," the statement said.

Former Real Madrid defender Marcelo, who now plays for Brazil's Fluminense, broke Argentinos Juniors defender's leg in a Copa Libertadores match in Buenos Aires. The defender, Luciano Sanchez, had his knee dislocated. The player will recover in about a year, Spanish sports website AS said. In the second half of the game, Marcelo, circling Sanchez, accidentally stepped on his leg when Sanchez threw it forward. Marcelo burst into tears because of the shocking incident and was sent off.

Too late Group E, Dinamo Moskva 6 games, six victories, 18 points, 9 goals scored, 3 against, passes through to the next round of the Europa League together with PSV Eindhoven (Netherlands). In Group H, Krasnodar had the first victory, away at Everton in the UK (city of Liverpool) but too late. Qualified for the next round: Borussia Mönchengladbach, Villarreal, Club Brugge, Torino, Besiktas, Tottenham, Red Bull Salzburg, Celtic, Inter, Dnipro, Feyenoord, Sevilla, Everton, Wolfsburg, Napoli, Young Boys, Dinamo Kiev, Steaua Bucuresti, Fiorentina, Guingamp, Legia Warsaw, Trabzonspor Played Won Drawn Lost Goals For Against Goal Difference Points

Canalys' recent global wearable band market analysis forecasts a 2% rise in 2023, totaling to 186 million units. This growth is primarily driven by a significant 22% surge in basic watch shipments in emerging markets, notably India.

Bankruptcy isn't a topic that anyone likes to discuss. Creditors, debtors, and government officials all get a little queasy at the thought of bankruptcy, but it exists for a reason. And in many situations, it can provide relief when financial friction is heightened. But bankruptcy isn't the same in every country. Laws, rules, and stigmas differ rather significantly - particularly between Russia and the United States. The what and why of bankruptcy Bankruptcy is one of the primary methods by which control over an asset can be transferred to more capable or efficient owners in the instance of market economies. Ultimately, bankruptcy serves three distinct purposes: To solve collective action problems among creditors as they deal with insolvent debtors. To give individual debtors a chance at a "fresh start" when they're overburdened by debt. To preserve/save the financial distress firms have by reorganizing rather than liquidating. Bankruptcy is basically government-sanctioned relief that allows individuals or businesses to have debts forgiven, granted they meet specific criteria and follow certain guidelines. It plays an important role in keeping the larger economic engine hitting on all cylinders. Without bankruptcy, millions of citizens would find themselves impoverished and unable to financially recover from dire situations.

In recognition of Cyber Security Awareness Month, Uswitch Broadband experts set out to explore how well people are protecting themselves online. The survey uncovered common mistakes that leave people vulnerable to cyber risks, along with actionable tips on how to safeguard personal information.

Former McDonald's restaurants in Kazakhstan have changed signs yet again. "We're Open" signs have been replaced with new "I am…" signs that contain proper names (in Kazakh language). For example, the signs of a restaurant in the city of Alma-Ata says "I am Madiyar." Other restaurants were called "I am Daniyar," I am Yulia," "I am Aray," I am Alexander," etc. Food Solutions KZ restaurant management company confirmed that the signs of former McDonald's restaurants were changed in six cities.

Leibinger introduced what it describes as the world’s first intelligent coding & marking system – the IQJET – on May 3 in Düsseldorf, the day before the opening of the interpack trade show.

US Congress will provide $61 billion in military aid to Ukraine. Will Joseph Biden decide to transfer long-range missiles to Kyiv? Does Washington prepare for a terrorist war against Russia? Pravda.Ru asked these and other questions to Alexander Dudchak, candidate of economic sciences, leading researcher at the Institute of CIS Countries. The US Congress approved $61 billion in aid to Ukraine, but this money will be distributed between Ukraine, the American military-industrial complex and allies in Europe for arms procurement. What do you think of the bill? The decision did not come as a surprise. Of course, the bulk of the amount will be spent to support the US defence industry. The Americans say that they need long-term contracts to support the defence industry, and Washington is getting them by supporting Kyiv and the hostilities in Ukraine. A lion's share of those billions will be spent to support the US defence industry in the first place. In addition, they will allocate money for the National Nuclear Safety Committee and the Ministry of Health.

[Domestic] :
Testimonies from surviving crew members who were aboard the fishing boat that sank in waters off Jeju Island on Friday suggest that the excessive amount of fish caught may have caused the ship to go down. According to the Jeju branch of the Korea Coast Guard on Saturday, all of the rescued crew members ...

[more...]

[Inter-Korea] :
The defense chiefs of South Korea and the United States have condemned the deployment of North Korean troops to Russia in the “strongest” terms with “one voice.” Defense Minister Kim Yong-hyun and U.S. Secretary of Defense Lloyd Austin issued the condemnation on Wednesday in a joint statement after ...

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[Sports] :
FIFA has slapped a ten-match ban on Italian footballer Marco Curto for making racist comments to Wolverhampton Wanderers forward Hwang Hee-chan during a pre-season friendly against Como 1907 back in July.  British sports media outlet, Sky Sports, quoted a spokesperson for the international football ...

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[Science] :
A heavy rain warning has been issued for the five border islands in the Yellow Sea and a heavy rain watch for the Seoul metro area, Gangwon Province and parts of the Jeolla and Gyeongsang provinces.  With heavy rain set to pound most parts of the nation through Sunday, the interior and safety ministry on ...

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[International] :
The price of Bitcoin surpassed the 80-thousand-dollar mark for the first time just days after Donald Trump’s reelection to the U.S. presidency.    According to the U.S. cryptocurrency exchange platform Coinbase, the world’s most popular cryptocurrency was worth 81-thousand-110 U.S. dollars at 1:25 a.m. ...

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In short, yes. Tomato-based catsup and ketchup are more or less the same condiment. There may be slight recipe variations on the traditional tomato-based version, but the main difference between ketchup and catsup is the alternative spelling of the same word.

NewJeans’ hit “Super Shy’ has earned a spot in Pitchfork’s list of the best songs of the decade. It was the only K-pop track to be featured on Pitchfork’s list of...

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Discover Taurus and Virgo compatibility in love, relationships, and friendship. Explore how these earth signs align in values, trust, and practical connections.

[Economy] :
The price of Bitcoin has crossed the 80-thousand-dollar mark for the first time, just days after Donald Trump’s reelection to the U.S. presidency.    According to the U.S. cryptocurrency exchange platform Coinbase, the world’s most popular cryptocurrency was trading at 88-thousand-413 U.S. dollars at ...

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X-rays can penetrate deeply into biological cells and thus allow for examination of their internal structures with high spatial resolution. In this study, X-ray phase-contrast imaging and tomography is combined with an X-ray-compatible optical stretcher and microfluidic sample delivery. Using this setup, individual cells can be kept in suspension while they are examined with the X-ray beam at a synchrotron. From the recorded holograms, 2D phase shift images that are proportional to the projected local electron density of the investigated cell can be calculated. From the tomographic reconstruction of multiple such projections the 3D electron density can be obtained. The cells can thus be studied in a hydrated or even living state, thus avoiding artifacts from freezing, drying or embedding, and can in principle also be subjected to different sample environments or mechanical strains. This combination of techniques is applied to living as well as fixed and stained NIH3T3 mouse fibroblasts and the effect of the beam energy on the phase shifts is investigated. Furthermore, a 3D algebraic reconstruction scheme and a dedicated mathematical description is used to follow the motion of the trapped cells in the optical stretcher for multiple rotations.

The widespread adoption of cryoEM technologies for structural biology has pushed the discipline to new frontiers. A significant worldwide effort has refined the single-particle analysis (SPA) workflow into a reasonably standardized procedure. Significant investments of development time have been made, particularly in sample preparation, microscope data-collection efficiency, pipeline analyses and data archiving. The widespread adoption of specific commercial microscopes, software for controlling them and best practices developed at facilities worldwide has also begun to establish a degree of standardization to data structures coming from the SPA workflow. There is opportunity to capitalize on this moment in the maturation of the field, to capture metadata from SPA experiments and correlate the metadata with experimental outcomes, which is presented here in a set of programs called EMinsight. This tool aims to prototype the framework and types of analyses that could lead to new insights into optimal microscope configurations as well as to define methods for metadata capture to assist with the archiving of cryoEM SPA data. It is also envisaged that this tool will be useful to microscope operators and facilities looking to rapidly generate reports on SPA data-collection and screening sessions.

Cryo-electron tomography (cryo-ET) enables molecular-resolution 3D imaging of complex biological specimens such as viral particles, cellular sections and, in some cases, whole cells. This enables the structural characterization of molecules in their near-native environments, without the need for purification or separation, thereby preserving biological information such as conformational states and spatial relationships between different molecular species. Subtomogram averaging is an image-processing workflow that allows users to leverage cryo-ET data to identify and localize target molecules, determine high-resolution structures of repeating molecular species and classify different conformational states. Here, STOPGAP, an open-source package for subtomogram averaging that is designed to provide users with fine control over each of these steps, is described. In providing detailed descriptions of the image-processing algorithms that STOPGAP uses, this manuscript is also intended to serve as a technical resource to users as well as for further community-driven software development.

The detection of specific biological macromolecules in cryogenic electron tomography data is frequently approached by applying cross-correlation-based 3D template matching. To reduce computational cost and noise, high binning is used to aggregate voxels before template matching. This remains a prevalent practice in both practical applications and methods development. Here, the relation between template size, shape and angular sampling is systematically evaluated to identify ribosomes in a ground-truth annotated data set. It is shown that at the commonly used binning, a detailed subtomogram average, a sphere and a heart emoji result in near-identical performance. These findings indicate that with current template-matching practices macromolecules can only be detected with high precision if their shape and size are sufficiently different from the background. Using theoretical considerations, the experimental results are rationalized and it is discussed why primarily low-frequency information remains at high binning and that template matching fails to be accurate because similarly shaped and sized macromolecules have similar low-frequency spectra. These challenges are discussed and potential enhancements for future template-matching methodologies are proposed.

Several proteins from plant pathogenesis-related family 10 (PR10) are highly abundant in the latex of opium poppy and have recently been shown to play diverse and important roles in the biosynthesis of benzylisoquinoline alkaloids (BIAs). The recent determination of the first crystal structures of PR10-10 showed how large conformational changes in a surface loop and adjacent β-strand are coupled to the binding of BIA compounds to the central hydrophobic binding pocket. A more detailed analysis of these conformational changes is now reported to further clarify how ligand binding is coupled to the formation and cleavage of an intermolecular disulfide bond that is only sterically allowed when the BIA binding pocket is empty. To decouple ligand binding from disulfide-bond formation, each of the two highly conserved cysteine residues (Cys59 and Cys155) in PR10-10 was replaced with serine using site-directed mutagenesis. Crystal structures of the Cys59Ser mutant were determined in the presence of papaverine and in the absence of exogenous BIA compounds. A crystal structure of the Cys155Ser mutant was also determined in the absence of exogenous BIA compounds. All three of these crystal structures reveal conformations similar to that of wild-type PR10-10 with bound BIA compounds. In the absence of exogenous BIA compounds, the Cys59Ser and Cys155Ser mutants appear to bind an unidentified ligand or mixture of ligands that was presumably introduced during expression of the proteins in Escherichia coli. The analysis of conformational changes triggered by the binding of BIA compounds suggests a molecular mechanism coupling ligand binding to the disruption of an intermolecular disulfide bond. This mechanism may be involved in the regulation of biosynthetic reactions in plants and possibly other organisms.

Investigation of the analyte soaking conditions on the crystalline sponge {[(ZnI2)3(tpt)2·x(solvent)]n} method using a statistical design of experiments model has provided fundamental insights into the influence of experimental variables. This approach focuses on a single analyte tested via 60 experiments (20 unique conditions) to identify the main effects for success and overall guest structure quality. This is employed as a basis for the development of a novel molecular structure grading system that enables the quantification of guest exchange quality.

Syntheses of the acyclic amidinium salts, morpholino­formamidinium hexa­fluorido­phosphate [OC4H8N—CH=NH2]PF6 or C5H11N2O+·PF6−, 1, and pyrrolidinoformamidinium hexa­fluorido­phosphate [C4H8N—CH= NH2]PF6 or C5H11N2+·PF6−, 2, were carried out by heating either morpholine or pyrrolidine with triethyl orthoformate and ammonium hexa­fluorido­phosphate. Crystals of 1 obtained directly from the reaction mixture contain one cation and one anion in the asymmetric unit. The structure involves cations linked in chains parallel to the b axis by N—H⋯O hydrogen bonds in space group Pbca, with glide-related chains pointing in opposite directions. Crystals of 1 obtained by recrystallization from ethanol, however, showed a similar unit cell and the same basic structure, but unexpectedly, there was positional disorder [occupancy ratio 0.639 (4):0.361 (4)] in one of the cation chains, which lowered the crystal symmetry to the non-centrosymmetric space group Pca21, with two cations and anions in the asymmetric unit. In the pyrrolidino compound, 2, cations and anions are ordered and are stacked separately, with zigzag N—H⋯F hydrogen-bonding between stacks, forming ribbons parallel to (101), extended along the b-axis direction. Slight differences in the delocalized C=N distances between the two cations may reflect the inductive effect of the oxygen atom in the morpholino compound.