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Quinone Methide Dimers Lacking Labile Hydrogen Atoms Are Surprisingly Excellent Radical-Trapping Antioxidants

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC02020F, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Derek A. Pratt, Mark A R Raycroft, Jean-Philippe R Chauvin, Matthew Galliher, Kevin Romero, Corey Stephenson
Hydrogen atom transfer (HAT) is the mechanism by which the vast majority of radical-trapping antioxidants (RTAs), such as hindered phenols, inhibit autoxidation. As such, at least one weak O–H bond...
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Near-infrared light-activated membrane fusion for cancer cell therapeutic applications

Chem. Sci., 2020, Accepted Manuscript
DOI: 10.1039/D0SC00863J, Edge Article
Open Access
  This article is licensed under a Creative Commons Attribution 3.0 Unported Licence.
Fujian Huang, Ruilin Duan, Zhixin Zhou, Margarita Vázquez-González, fan xia, Itamar Willner
The spatiotemporal stimulation of liposome-liposome or liposome-membrane fusion processes attracts growing interest as a means to mimic cell-cell interactions in nature and for using these processes for biomedical applications. We...
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Loose parts : inspiring play in young children / Lisa Daly and Miriam Beloglovsky ; photography by Jenna Daly

Daly, Lisa




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Geographical Modeling: Cities and Territories


 
The modeling of cities and territories has progressed greatly in the last 20 years. This is firstly due to geographic information systems, followed by the availability of large amounts of georeferenced data both on the Internet and through the use of connected objects. In addition, the rise in performance of computational methods for the simulation and exploration of dynamic models has facilitated advancement. Geographical Modeling presents previously

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Should Younger Male Cancer Survivors Get Testosterone Therapy?

Male cancer survivors aged 25 through 50 years who received testosterone replacement had decreased body fat and increased muscle mass in a PLOS Medicine trial.




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Mathematical Analysis I: Approximation Theory: ICRAPAM 2018, New Delhi, India, October 23-25 / Naokant Deo, Vijay Gupta, Ana Maria Acu, P. N. Agrawal, editors

Online Resource




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A liquid biopsy-guided drug release system for cancer theranostics: integrating rapid circulating tumor cell detection and precision tumor therapy

Lab Chip, 2020, 20,1418-1425
DOI: 10.1039/D0LC00149J, Paper
Chun-Miao Xu, Man Tang, Jiao Feng, Hou-Fu Xia, Ling-Ling Wu, Dai-Wen Pang, Gang Chen, Zhi-Ling Zhang
A system integrating diagnostic and therapeutic functions for cancer is presented using magnetically controlled microfluidics.
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Rapid lipolytic oscillations in ex vivo adipose tissue explants revealed through microfluidic droplet sampling at high temporal resolution

Lab Chip, 2020, 20,1503-1512
DOI: 10.1039/D0LC00103A, Paper
Juan Hu, Xiangpeng Li, Robert L. Judd, Christopher J. Easley
High temporal resolution sampling and quantitative detection of glycerol secretion dynamics from adipose tissue using our automated, droplet-based microfluidic system.
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Stretching DNA to twice the normal length with single-molecule hydrodynamic trapping

Lab Chip, 2020, Advance Article
DOI: 10.1039/C9LC01028A, Paper
Open Access
Yan Jiang, Theodore Feldman, Julia A. M. Bakx, Darren Yang, Wesley P. Wong
High-speed hydrodynamic trapping enables combined surface-free force spectroscopy and fluorescence imaging of single DNA molecules at extreme forces.
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PRESCIENT: platform for the rapid evaluation of antibody success using integrated microfluidics enabled technology

Lab Chip, 2020, 20,1628-1638
DOI: 10.1039/C9LC01165J, Paper
Jose A. Wippold, Han Wang, Joseph Tingling, Julian L. Leibowitz, Paul de Figueiredo, Arum Han
Identifying antibodies (Abs) that neutralize infectious agents is the first step for developing therapeutics, vaccines, and diagnostic tools for these infectious agents.
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The life of Saint Teresa of Avila: a biography / Carlos Eire

Online Resource




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The Book of Exodus: a Biography / Joel S. Baden

Online Resource




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The history of the brain and mind sciences: technique, technology, therapy / edited by Stephen T. Casper and Delia Gavrus

Hayden Library - QP360.H57 2017




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Mama's last hug: animal emotions and what they tell us about ourselves / Frans de Waal ; with photographs and drawings by the author

Hayden Library - QL785.27.W33 2019




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Mathematical Modelling and Biomechanics of the Brain Corina Drapaca, Siv Sivaloganathan

Online Resource




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September 1, 1939: a biography of a poem / Ian Sansom

Dewey Library - PR6001.U4 Z796 2019




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Frankenstein 200: the birth, life, and resurrection of Mary Shelley's monster / Rebecca Baumann ; photographs by Jody Mitchell

Dewey Library - PR5397.F73 B384 2018




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Gene therapy effective for treating wet age-related macular degeneration: Study

Researchers said the hope is that gene therapy will free patients from nearly monthly eye injections by offering a potential "one-and-done" treatment.




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Evolutionary Economic Geography in China [electronic resource] / by Canfei He, Shengjun Zhu

He, Canfei, author




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The Making of the Banlieue [electronic resource]: An Ethnography of Space, Identity and Violence

Slooter, Luuk




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Chromatographic detection of low-molecular-mass metal complexes in the cytosol of Saccharomyces cerevisiae

Metallomics, 2020, Advance Article
DOI: 10.1039/C9MT00312F, Paper
Open Access
Trang Q. Nguyen, Joshua E. Kim, Hayley N. Brawley, Paul A. Lindahl
Labile metal pools in the cytosol of yeast, including those of iron, copper, zinc, and manganese, can be detected and characterized using size-exclusion chromatography with online ICP-MS.
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Immunotherapy drug improves outcomes for some children with relapsed leukemia

For children and young adults with certain relapsed B-cell acute lymphoblastic leukemia (B-ALL), the immunotherapy drug blinatumomab is superior to standard chemotherapy, an NCI-sponsored Children’s Oncology Group trial shows.




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Graphit: Gedichte / Marcel Beyer

Hayden Library - PT2662.E94 G7 2014




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On photography / Walter Benjamin; edited and translated by Esther Leslie

Rotch Library - PT2603.E455 O53 2015




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The Red Countess: Select Autobiographical and Fictional Writing of Hermynia Zur Mühlen (1883-1951).

Online Resource




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The topography of modernity: Karl Philipp Moritz and the space of autonomy / Elliott Schreiber

Online Resource




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Science Podcast - Quantum cryptography, salt's role in ecosystems, and a rundown of stories from our daily news site (31 Jan 2014)

Should we worry more about quantum decryption in the future or the past, how salt's role as a micronutrient may effect the global carbon cycle, and a daily news roundup.




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Science Podcast - 100 years of crystallography, linking malaria and climate, and a news roundup (7 Mar 2014)

Celebrating crystallography's centennial; how climate pushes malaria uphill; roundup of daily news with David Grimm.




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AI therapists and a news roundup

John Bohannon discusses using artificial intelligence in the psychologist's chair and David Grimm brings online news stories about the age of human hands, deadly weather, and biological GPS. Hosted by Sarah Crespi. [Img:Nils Rinaldi/Flickr]




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3-parent gene therapy for mitochondrial diseases and a news roundup

Kimberly Dunham-Snary discusses the long-term health considerations of gene therapy for mitochondrial diseases and David Grimm talks about the smell of death, Mercury crashing, and animal IQ. Hosted by Susanne Bard. [Image credit: Ben Gracewood CC BY-NC 2.0, via flickr]




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Podcast: A recipe for clean and tasty drinking water, a gauge on rapidly rising seas, and fake flowers that can fool the most discerning insects

Online News Editor Catherine Matacic shares stories on what we can learn from 6million years of climate data, how to make lifelike orchids with 3D printing, and crowdsourced gender bias on eBay.   Fernando Rosario-Ortiz joins host Sarah Crespi to discuss how approaches to water purification differ between countries.   [Image: Eric Hunt/Wikipedia/CC BY-SA 3.0] 0]




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Podcast: Ceres’s close-up, how dogs listen, and a new RNA therapy

News stories on what words dogs know, an RNA therapy for psoriasis, and how Lucy may have fallen from the sky, with Catherine Matacic.  From the magazine In early 2015, NASA’s Dawn spacecraft entered orbit around Ceres, the largest object in the asteroid belt. Over the last year and a half, scientists have studied the mysterious dwarf planet using data collected by Dawn, including detailed images of its surface. Julia Rosen talks with Debra Buczkowski about Ceres’s close-up.  See the full Ceres package.




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Podcast: Explaining menopause in killer whales, triggering killer mice, and the role of chromosome number in cancer immunotherapy

This week, we chat about a surprising reason why killer whales undergo menopause, flipping a kill switch in mice with lasers, and Fukushima residents who measured their own radiation exposure[link tk], with Online News Editor Catherine Matacic. Plus, Science’s Alexa Billow talks to Stephen Elledge about the relationship between chromosomal abnormalities in tumors and immunotherapy for cancer.   Listen to previous podcasts.   [Image: Copyright Kenneth Balcomb Center for Whale Research; Music: Jeffrey Cook]




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DNA and proteins from ancient books, music made from data, and the keys to poverty traps

This week we hear stories on turning data sets into symphonies for business and pleasure, why so much of the world is stuck in the poverty trap, and calls for stiffening statistical significance with Online News Editor David Grimm. Sarah Crespi talks to news writer Ann Gibbons about the biology of ancient books—what can we learn from DNA, proteins, and book worm trails about a book, its scribes, and its readers? Listen to previous podcasts. [Music: Jeffrey Cook]




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How Earth’s rotation could predict giant quakes, gene therapy’s new hope, and how carbon monoxide helps deep-diving seals

This week we hear stories on how the sloshing of Earth’s core may spike major earthquakes, carbon monoxide’s role in keeping deep diving elephant seals oxygenated, and a festival celebrating heavily researched yet completely nonsensical theories with Online News Editor David Grimm. Sarah Crespi interviews staff writer Jocelyn Kaiser about the status of gene therapy, including a newly tested gene-delivering virus that may give scientists a new way to treat devastating spinal and brain diseases. Listen to previous podcasts.    [Image: Robert Schwemmer, CINMS, NOAA; Music: Jeffrey Cook]  




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Who visits raccoon latrines, and boosting cancer therapy with gut microbes

David Grimm—online news editor for Science—talks with Sarah Crespi about a long-term project monitoring raccoon latrines in California. What influence do these wild bathrooms have on the ecosystem? Sarah also interviews Christian Jobin of the University of Florida in Gainesville about his Perspective on three papers linking the success of cancer immunotherapy with microbes in the gut—it turns out which bacteria live in a cancer patient’s intestines can predict their response to this cutting-edge cancer treatment. Read the related papers: Routy et al., Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors, Science 2018 Gopalakrishnan et al., Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients, Science 2018 Matson et al., The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients, Science 2018 aan4236 Listen to previous podcasts. [Image: cuatrok77/Flickr; Music: Jeffrey Cook]




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Areas to watch in 2020, and how carnivorous plants evolved impressive traps

We start our first episode of the new year looking at future trends in policy and research with host Joel Goldberg and several Science News writers. Jeffrey Mervis discusses upcoming policy changes, Kelly Servick gives a rundown of areas to watch in the life sciences, and Ann Gibbons talks about potential advances in ancient proteins and DNA. In research news, host Meagan Cantwell talks with Beatriz Pinto-Goncalves, a postdoctoral researcher at the John Innes Centre, about carnivorous plant traps. Through understanding the mechanisms that create these traps, Pinto-Goncalves and colleagues elucidate what this could mean for how they emerged in the evolutionary history of plants. This week’s episode was edited by Podigy. Ads on this week’s show: KiwiCo Download a transcript (PDF) Listen to previous podcasts. About the Science Podcast  




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Crystallography and Crystal Defects, 3rd Edition


 

The classic book that presents a unified approach to crystallography and the defects found within crystals, revised and updated

This new edition of Crystallography and Crystal Defectsexplains the modern concepts of crystallography in a clear, succinct manner and shows how to apply these concepts in the analyses of point, line and planar defects in crystalline materials. 

Fully revised and updated, this book now includes:



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Political Geography: A Critical Introduction


 

Brings political geography to life—explores key concepts, critical debates, and contemporary research in the field. 

Political geography is the study of how power struggles both shape and are shaped by the places in which they occur—the spatial nature of political power. PoliticalGeography: A Critical Introduction helps students understand how power is related to space, place, and territory, illustrating how everyday life and the world of global conflict



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A membraneless gas-trapping device for cyanide detection and quantification

Anal. Methods, 2020, 12,2009-2015
DOI: 10.1039/D0AY00245C, Paper
Chatipat Lorpaiboon, Wanutcha Lorpaiboon, Manchuta Dangkulwanich
A novel device for trapping gaseous compounds was invented and employed to create a user-friendly cyanide test kit for aqueous solutions.
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Evaluation of segmented non-target data acquisition (SWATH/vDIA) in a QToF and QOrbitrap for pesticide residue analysis

Anal. Methods, 2020, 12,2027-2038
DOI: 10.1039/D0AY00290A, Paper
Łukasz Rajski, Iciar Beraza, María José Gómez Ramos, Carmen Ferrer, Amadeo R. Fernández-Alba
Two high-resolution instruments (a QToF and a QOrbitrap) were used to evaluate a segmented non-target MS2 (SWATH/vDIA) acquisition for pesticide residue analysis.
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Liquid–liquid microextraction of glyphosate, glufosinate and aminomethylphosphonic acid for the analysis of agricultural samples by liquid chromatography

Anal. Methods, 2020, 12,2039-2045
DOI: 10.1039/D0AY00120A, Paper
Javier Marín, Natalia Campillo, Manuel Hernández-Córdoba, Isabel Garrido, José Fenoll, Pilar Viñas
An ion-pair liquid–liquid microextraction procedure followed by LC tandem mass spectrometry allows a reliable and sensitive determination glyphosate, glufosinate y aminomethylphosphonic acid in agricultural samples.
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Molecular analysis of edible bird’s nest and rapid authentication of Aerodramus fuciphagus from its subspecies by PCR-RFLP based on the cytb gene

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/C9AY02548K, Paper
Kunfeng Liu, Maoyong Wu, Xuemei Lin, Piyanuch Lonan, Sitai Chen, Yina Wu, Xiaoping Lai, Liangwen Yu, Xiaoming Zhou, Geng Li
Edible bird's nest (EBN), for its great nutritional value, is widely used around the world, especially in China and Singapore. EBNs of different origins and types may vary in price...
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A simple and rapid method for blood plasma separation driven by capillary force with an application on protein detection

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00240B, Paper
Qingxue Gao, Yongjia Chang, Qingmei Deng, Hui You
Blood plasma separation is a vital sample pre-treatment procedure for microfluidic devices of blood diagnostic, which requires reliability and speediness. In this work, we propose a novel and simple method...
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Effective methods for the determination of triphenyltin residues in surface water and soil samples by high-performance liquid chromatography with tandem mass spectrometry

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00329H, Paper
Gabriel C. dos Santos, Állisson A. da S. Avellar, Rômulo de O. Schwaickhardt, Nelson M. G. Bandeira, Filipe F. Donato, Osmar D. Prestes, Renato Zanella
Monitoring of triphenyltin (TPhT) in the environment, particularly to control its misuse in agriculture, is of great importance because of its high toxicity.
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Development of a magnetic dispersive micro-solid-phase extraction method based on a deep eutectic solvent as a carrier for the rapid determination of meloxicam in biological samples

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00095G, Paper
Samira Rastbood, Mohammad Reza Hadjmohammadi, Seyedeh Maedeh Majidi
An environmentally friendly magnetic dispersive micro solid phase extraction based on a deep eutectic solvent as a carrier and disperser of adsorbents.
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Rapid detection of quality of Japanese fermented soy sauce using near-infrared spectroscopy

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00521E, Paper
Shuo Wang, Takehiro Tamura, Nobuyuki Kyouno, Xiaofang Liu, Han Zhang, Yoshinobu Akiyama, Jie Yu Chen
The application of NIR spectroscopy has great potential as an alternative quality control method, which provides a robust model for routinely estimating the final quality of soy sauce production rapidly and economically.
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Dopamine-modified magnetic graphene oxide as a recoverable sorbent for the preconcentration of metal ions by an effervescence-assisted dispersive micro solid-phase extraction procedure

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00522C, Paper
Basira Karbalaie, Maryam Rajabi, Bahareh Fahimirad
Nanomagnetic graphene oxide modified with dopamine (GO–Fe3O4–DA) was synthesized via a very simple procedure.
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Targeted profiling of amino acid metabolome in serum by a liquid chromatography-mass spectrometry method: application to identify potential markers for diet-induced hyperlipidemia

Anal. Methods, 2020, Advance Article
DOI: 10.1039/D0AY00305K, Paper
Xiao-fan Wang, You-xi Zhang, Hai-ying Ma
Targeted profiling of amino acid metabolome in serum by LC-MS: application to identify potential markers for diet-induced hyperlipidemia.
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Derivatization and rapid GC—MS screening of chlorides relevant to the Chemical Weapons Convention in organic liquid samples

Anal. Methods, 2020, Accepted Manuscript
DOI: 10.1039/D0AY00263A, Paper
Open Access
Marja-Leena Kuitunen, Jorgelina Cecilia Altamirano, Peter Siegenthaler, Terhi Hannele Taure, Vesa Mauri Antero Häkkinen, Paula Vanninen
A simple derivatization technique was developed for the analysis of seven Schedule 3 chemicals and one Schedule 2 chemical listed in the Chemical Weapons Conventions (CWC). Phosgene, phosphorus oxychloride, phosphorus...
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