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Special Investment Facilitation Council Reviews Progress and Strategies for Economic Stability in Pakistan

The Apex Committee of the Special Investment Facilitation Council (SIFC) met to evaluate advancements in fostering investments in Pakistan. Chaired by the caretaker prime minister, discussions encompassed strategies such as the privatization of financially struggling government institutions. In a separate interaction, the Army Chief reiterated the armed forces’ dedication to supporting the nation’s economic stability. ... Read more

The post Special Investment Facilitation Council Reviews Progress and Strategies for Economic Stability in Pakistan appeared first on Pakistan Tribune.




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Financial Investigative Reporting and Mentorship Initiative

Financial Investigative Reporting and Mentorship Initiative

reyesm1




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Public Protector declines to investigate Ramaphosa over Simelane loan scandal




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Calls for investigation following Gwamanda’s dismissal as MMC for Community Development




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SIU investigates corruption allegations against SASRIA following July 2021 unrest




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When Unbelief Investigates a Miracle




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Global Divestment Day: Shifting Investments to Clean Energy

The divestment movement aims to combat climate change by stripping investments from fossil fuels and redirecting them toward renewable energy.




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China's Asian Infrastructure Investment Bank

The AIIB is a game changer for China in multilateral financial architecture. The Bank presents both a challenge and an opportunity for India.




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SM Investments nets P60.9B

SM Investments Corp., led by the billionaire Sy family, booked a 9-percent gain in earnings in the January to September period to P60.9 billion as falling interest rates buoyed its banking unit. In a stock exchange filing on Wednesday, SMIC said revenues reached P462.5 billion, up by 5 percent. READ: BIZ BUZZ: SM is conglomerate of the year “We continued to see good growth across our businesses in the third quarter,” SMIC president and CEO Frederic DyBuncio said in a statement. “With inflation easing, we remain positive. An improving macroeconomic environment should help both our businesses and consumers moving forward,” […]...

Keep on reading: SM Investments nets P60.9B




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World Governments, NGOs Announce $350m Investments in Sexual and Reproductive Health Services

On the heels of the Summit of the Future and the sidelines of the United Nations High-Level Meeting Week, governments and philanthropies pledged to commit at least USD 350 million to boost family planning, sexual and reproductive health and supplies on the national and global level. As enshrined in the newly-adopted Pact for the Future, […]




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Cyprus grows as a hub for alternative investment funds

“Cyprus has gone from zero to over 330 licensed investment entities managing €9 billion in assets in just a decade,” according to Maria Panayiotou, president of the Cyprus Investment Fund Association (CIFA). Speaking at the 5th Fund and Asset Management Conference in Athens, Panayiotou attributed this growth to “relentless effort and strategic vision.” She added […]




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2024 Asian Regional Forum on Investment Management of Foreign Exchange Reserves - Roberta Casali

Opening remarks by Roberta Casali, ADB Vice-President for Finance and Risk Management, at the 2024 Asian Regional Forum on Investment Management of Foreign Exchange Reserves, 25 September 2024, Japan




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By Investing in Technical Training, a Brighter Future Beckons for the Youth of Bhutan

The Asian Development Bank is ramping up investment in technical and vocational education and training in Bhutan, which is helping to train thousands




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Senior Investment Specialist

ADB has a vacancy for the position of Senior Investment Specialist in the Private Sector Operations Department. The deadline for submitting applications is on 25-NOV-2024.




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Morrison police chief Bill Vinelli on leave amid investigation

“While the investigation takes place, the town will refrain from any additional comment on this matter," according to a press release.




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Foreign Direct Investment in South Asia: Policy, Trends, Impact and Determinants

South Asia study of foreign direct investments impact in India, Pakistan, Bangladesh, Sri Lanka and Nepal on economic growth, domestic investment, and export; special emphasis on the role of infrastructure.



  • Publications/Papers and Briefs

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Policy Environment and Regulatory Reforms for Private and Foreign Investment in Developing Countries: A Case of the Indian Power Sector

To attract infrastructure investment to meet national goals for providing electricity to consumers, India needs continued macroeconomic stability as well as an improved policy and regulatory environment.



  • Publications/Papers and Briefs

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People's Republic of China and Its Neighbors: Partners or Competitors for Trade and Investment?

How has the recent dramatic growth of PRC's exports affected its neighbors? Have they lost export markets and seen foreign investment diverted to PRC? This paper surveys the empirical evidence on these important questions.



  • Publications/Papers and Briefs

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Loan No. 2972-PAK: Power Distribution Enhancement Investment Program, Tranche-III [ADB-TRANCHE-III-MEPCO-01]




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Loan No. 2924-IND: Uttarakhand Power Sector Investment Program - Project 4 [ICB No. 3-P/ADB/PTCUL/2012-13]




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Loan No. 3411-AZE: Water Supply and Sanitation Investment Program - Tranche 4 [MFF42408-044-T4-ICB-1.02]




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Loan Nos. 3076/3077-PNG: Highland Region Road Improvement Investment Program [CSTB No. 2946]




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Loan No. 42401-AZE: Power Distribution Enhancement Investment Program - Tranche 1 [AI/ADB-10.1 and AI/ADB-10.2]




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Loan No. 3203-PAK: Power Transmission Enhancement Investment Program Tranche 4 [ADB-79-2015] EXTENDED




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Loan No. 2972-PAK: Power Distribution Enhancement Investment Program - Tranche 3 [LESCO-10-2013]




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Loan No. 2830-IND: Madhya Pradesh Energy Efficiency Improvement Investment Program – Tranche 2 [MD / WZ / 06 / PUR / ADB /993]




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MFF: Green and Resilience Financing Facility Investment Program

The proposed program is a large-scale transformative and integrated initiative addressing the constraints. It aims to bridge the financing, capacity, institutional, and technical gaps in implementing the NAP and adaptation measures mentioned in the NDC and GRID while promoting mitigation, biodiversity, air pollution, and food security as co-benefits.




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Is life better as a dog? A philosopher investigates

What is it like to be a dog? And what can we learn from them? Mark Rowlands's take, in his book The Happiness of Dogs, is full of insights, finds Abigail Beall




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VA Hospital Delays Didn't Cause Deaths, Investigators Say

Title: VA Hospital Delays Didn't Cause Deaths, Investigators Say
Category: Health News
Created: 8/26/2014 12:35:00 PM
Last Editorial Review: 8/27/2014 12:00:00 AM




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CDC Investigating E. coli Outbreak in Ohio, Michigan

Title: CDC Investigating E. coli Outbreak in Ohio, Michigan
Category: Health News
Created: 8/18/2022 12:00:00 AM
Last Editorial Review: 8/19/2022 12:00:00 AM




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Investigations into the Concentrations and Metabolite Profiles of Doping Agents and Antidepressants in Human Seminal Fluid Using Liquid Chromatography-Mass Spectrometry [Articles]

Exogenous substances, including drugs and chemicals, can transfer into human seminal fluid and influence male fertility and reproduction. In addition, substances relevant in the context of sports drug testing programs, can be transferred into the urine of a female athlete (after unprotected sexual intercourse) and trigger a so-called adverse analytical finding. Here, the question arises as to whether it is possible to distinguish analytically between intentional doping offenses and unintentional contamination of urine by seminal fluid. To this end, 480 seminal fluids from nonathletes were analyzed to identify concentration ranges and metabolite profiles of therapeutic drugs that are also classified as doping agents. Therefore, a screening procedure was developed using liquid chromatography connected to a triple quadrupole mass spectrometer, and suspect samples (i.e., samples indicating the presence of relevant compounds) were further subjected to liquid chromatography-high-resolution accurate mass (tandem) mass spectrometry. The screening method yielded 90 findings (including aromatase inhibitors, selective estrogen receptor modulators, diuretics, stimulants, glucocorticoids, beta-blockers, antidepressants, and the nonapproved proliferator-activated receptor delta agonist GW1516) in a total of 81 samples, with 91% of these suspected cases being verified by the confirmation method. In addition to the intact drug, phase-I and -II metabolites were also occasionally observed in the seminal fluid. This study demonstrated that various drugs including those categorized as doping agents partition into seminal fluid. Monitoring substances and metabolites may contribute to a better understanding of the distribution and metabolism of exogenous substances in seminal fluid that may be responsible for the impairment of male fertility.

SIGNIFICANCE STATEMENT

This study demonstrates that doping agents as well as clinically relevant substances are transferred/eliminated into seminal fluid to a substantial extent and that knowledge about drug levels (and potential consequences for the male fertility and female exposure) is limited. The herein generated new dataset provides new insights into an important and yet little explored area of drug deposition and elimination, and hereby a basis for the assessment of contamination cases by seminal fluid in sports drug testing.




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Preclinical Investigation of [212Pb]Pb-DOTAM-GRPR1 for Peptide Receptor Radionuclide Therapy in a Prostate Tumor Model

The role of gastrin-releasing peptide receptor (GRPR) in various diseases, including cancer, has been extensively studied and has emerged as a promising therapeutic target. In this study, we successfully achieved the use of [212Pb]Pb-DOTAM-GRPR1, comprising the α-particle generator, 212Pb, combined with a GRPR-targeting peptide, GRPR1, in a prostate cancer model. Methods: Pharmacokinetics, toxicity, radiation dosimetry, and efficacy were assessed in GRPR-positive prostate tumor–bearing mice after intravenous administration of [212Pb]Pb-DOTAM-GRPR1 (where DOTAM is 1,4,7,10-tetrakis(carbamoylmethyl)-1,4,7,10-tetraazacyclododecane). Results: Preclinical studies have shown tumor targeting of up to 5 percent injected dose per gram over 24 h, and optimization of the drug formulation and quantity has led to minimized oxidation and off-target binding, respectively. Particularly, an increase in peptide amount from 28 to 280 ng was shown to reduce off-target uptake, especially at the level of the pancreas, by about 30%. Furthermore, dosimetry studies confirmed the kidney as the dose-limiting organ, and toxicity studies revealed that a nontoxic dose of up to 1,665 kBq could be injected into mice. Efficacy studies indicated a median survival time of 9 wk in the control group, which received only a buffer solution, compared with 19 wk in the group that received 4 injections of 370 kBq at 3-wk intervals. Conclusion: Taken together, these combined data demonstrate the safety, tolerability, and efficacy of [212Pb]Pb-DOTAM-GRPR1, thus warranting further exploration in clinical trials.




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Overseas boost for Scots tourism as investment giant toils

International numbers are on the up but not everything in tourism is rosy




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Fire chiefs hail £30m investment in ‘whole new level’ 999 emergency system

The technology will deliver enhanced day-to-day and major incident response capability




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Scottish investment group sells off software subsidiary

Scottish investment giant abrdn has sold its Focus Solutions software business and is said to be eyeing other potential disposals




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ESA prepares Hera mission to investigate aftermath of NASA DART impact

The European Space Agency's Hera spacecraft must be thoroughly tested before being sent to investigate the aftermath of the collision of NASA's DART probe with Dimorphos




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Can AI make crime scene investigations less biased?

AI tools could help eliminate human bias in forensic investigations, say UCL scientists, who are using eye-tracking technology to study decision-making in skeletal analysis and crime scene examinations




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Competition Bureau obtains court order to further investigation into Google’s ad practices

The Competition Bureau has announced that it has expanded its investigation into Google’s online ad practices. This is the first major update to the investigation since it began in 2020, and a year later the competition watchdog obtained a court order from the Federal Courts of Appeal, requiring Google to produce records and written information […]

The post Competition Bureau obtains court order to further investigation into Google’s ad practices first appeared on ITBusiness.ca.




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Government of Canada announces major broadband investments in the west

The government of Canada has announced significant investments to improve connectivity in British Columbia and Alberta over the past two days. That includes combined federal and provincial funding of C$112 million to bring high speed internet access to more than 22,500 households in Alta. and another $37 million for 7,500 households in B.C.. The households, […]

The post Government of Canada announces major broadband investments in the west first appeared on ITBusiness.ca.



  • Communications & Telecom
  • Government & Public Sector
  • Government of Canada
  • government-of-alberta
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  • Top Story

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Body found in search for missing mum Jane Burton as police launch investigation



Greater Manchester Police launched a public appeal to help find Jane Burton on Tuesday morning but have paused the search after a body was found




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Scientists Investigate Inner Workings of DNA Methylation in Plants

DNA methylation is one of several epigenetic mechanisms crucial for regulating gene expression in eukaryotic organisms.

The post Scientists Investigate Inner Workings of DNA Methylation in Plants appeared first on Sci.News: Breaking Science News.




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Sweden reopens Salmonella outbreak investigation

An investigation into a Salmonella outbreak in Sweden has been restarted after more people fell sick. From August to October, 81 people from 18 regions contracted Salmonella Typhimurium with sequence type (ST) 36. Where information about the country of infection is available, all cases were infected in Sweden. Folkhälsomyndigheten (the Public... Continue Reading




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CDC investigating 21 outbreaks

The Centers for Disease Control and Prevention typically coordinates between 17 and 36 investigations of foodborne illnesses involving multiple states each week.  A report is posted weekly, but does not include any information about where the outbreaks are occurring, what foods are involved, or how many patients have been identified.... Continue Reading




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Montana officials investigating new outbreak of Salmonella infections at schools

Montana public health officials are investigating an outbreak of infections caused by Salmonella. The Cascade City-County Health Department in Great Falls is reporting that six students at Sacajawea and Valley View elementary schools have tested positive for the pathogen. A staff member at another school has also tested positive. There... Continue Reading




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South Africa investigates local shops as death toll passes 20

More than 20 people are believed to have died in one South African province after consuming food from local shops. Gauteng Premier Panyaza Lesufi said the majority of deaths have been children aged between six and nine. “The first uniform approach across the province was to adopt a mechanism of... Continue Reading




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AIMCo expansion, Alberta's investment focus were sources of tension before purge, sources say

Pension veterans say there was more going on behind the scenes than scrutiny of costs




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Microsoft reports big profits amid massive AI investments

Xbox hardware sales dropped 29 percent, but that barely made a dent.




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NASA completes spacecraft for TRACERS mission to investigate hazardous solar storms

Solar storms have the ability to harm astronauts and force massive blackouts




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Dropbox lays off 20% of staff, says it overinvested and underperformed

Dropbox also laid off 500 last year but still had "excess layers of management."




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‘Sikandar Ka Muqaddar’ trailer: Jimmy Shergill untiringly investigates a diamond heist

Tamannaah Bhatia, Avinash Tiwary and Rajiv Mehta play three unlikely suspects in director Neeraj Pandey’s latest