ic Medical evaluation of long-term methadone-maintained clients / edited by Herbert D. Kleber, Frank Slobetz and Marjorie Mezritz. By search.wellcomelibrary.org Published On :: Rockville, Maryland : National Institute on Drug Abuse, 1980. Full Article
ic National polydrug collaborative project : treatment manual I : medical treatment for complications of polydrug abuse. By search.wellcomelibrary.org Published On :: Rockville, Maryland : National Institute on Drug Abuse, 1978. Full Article
ic Lipolicious! By search.wellcomelibrary.org Published On :: [London] : [publisher not identified], [2019] Full Article
ic National transportation safety board public forum on alcohol and drug safety education. By search.wellcomelibrary.org Published On :: Springfield, Virginia : National Technical Information Service, 1986. Full Article
ic The incidence of driving under the influence of drugs, 1985 : an update of the state of knowledge / [Richard P. Compton and Theodore E. Anderson]. By search.wellcomelibrary.org Published On :: Springfield, Virginia : National Technical Information Service, 1985. Full Article
ic Survey of drug information needs and problems associated with communications directed to practicing physicians : part III : remedial ad survey / [Arthur Ruskin, M.D.] By search.wellcomelibrary.org Published On :: Springfield, Virginia : National Technical Information Service, 1974. Full Article
ic Identifying on-the-job behavioral manifestations of drug abuse : a guide for work supervisors / [Harold Reinich]. By search.wellcomelibrary.org Published On :: New York : Experimental Manpower Laboratory at Mobilization for Youth, Inc., [1971] Full Article
ic Co-ordinating drugs services : the role of regional and district drug advisory committees : a preliminary study for the Department of Health / by Peter Baker and Dorothy Runnicles. By search.wellcomelibrary.org Published On :: London : London Research Centre, 1991. Full Article
ic Monitoring and evaluation : alcoholism and other drug dependence services. By search.wellcomelibrary.org Published On :: Chicago, Ill. : Joint Commission on Accreditation of Healthcare Organizations, 1987. Full Article
ic Drug-related social work in street agencies : a study by the Institute for the Study of Drug Dependence / Nicholas Dorn and Nigel South. By search.wellcomelibrary.org Published On :: Norwich : University of East Anglia : Social Work Today, 1984. Full Article
ic Policy and guidelines for the provision of needle and syringe exchange services to young people / Tom Aldridge and Andrew Preston. By search.wellcomelibrary.org Published On :: [Dorchester] : Dorset Community NHS Trust, 1997. Full Article
ic Methadone substitution therapy : policies and practices / edited by Hamid Ghodse, Carmel Clancy, Adenekan Oyefeso. By search.wellcomelibrary.org Published On :: London : European Collaborating Centres in Addiction Studies, 1998. Full Article
ic Evaluation of the 'progress' pilot projects "from recovery into work" / by Stephen Burniston, Jo Cutter, Neil Shaw, Michael Dodd. By search.wellcomelibrary.org Published On :: York : York Consulting, 2001. Full Article
ic The university chemical dependency project : final report : November 1 1986 / Steven A. Bloch, Steven Ungerleider. By search.wellcomelibrary.org Published On :: [Indiana] : Integrated Research Services, Inc., 1986. Full Article
ic New essays on abortion and bioethics / volume editor, Rem B. Edwards. By search.wellcomelibrary.org Published On :: Greenwich, Conn. : Jai Press Inc., 1997. Full Article
ic Proceedings of the Parapsychological Association. By search.wellcomelibrary.org Published On :: Durham, North Carolina : [Duke Station, 1957-[197-?] Full Article
ic Collection 03: Gaye Chapman picture book artwork, 2005-2015 By feedproxy.google.com Published On :: 29/09/2015 12:00:00 AM Full Article
ic Series 02: Merle Highet sound recordings of Frederick Rose, 1990 By feedproxy.google.com Published On :: 30/09/2015 9:43:23 AM Full Article
ic Victor J. Daley bibliography, 1885 By feedproxy.google.com Published On :: 30/09/2015 12:00:00 AM Full Article
ic Series 02: H.C. Dorman pictorial material, 1960-1967 By feedproxy.google.com Published On :: 1/10/2015 12:00:00 AM Full Article
ic Wedding photographs of William Thomas Cadell and Anne Macansh set in Harriet Scott graphic By feedproxy.google.com Published On :: 9/10/2015 12:00:00 AM Full Article
ic Echelet picumne and echelet grimpeur, male / by Jean Gabriel Prêtre, 1824 By feedproxy.google.com Published On :: 9/10/2015 12:00:00 AM Full Article
ic Sydney in 1848 : illustrated by copper-plate engravings of its principal streets, public buildings, churches, chapels, etc. / from drawings by Joseph Fowles. By feedproxy.google.com Published On :: 28/04/2016 12:00:00 AM Full Article
ic Digitisation Officer appointed By www.sl.nsw.gov.au Published On :: Thu, 10 Sep 2015 02:50:12 +0000 Digitisation Officer appointed I am pleased to introduce our new Digitisation Officer, Lauren O'Brien. Her main f Full Article
ic Sabrina Ionescu, Ruthy Hebard, Satou Sabally on staying connected, WNBA Draft, Oregon's historic season By sports.yahoo.com Published On :: Thu, 09 Apr 2020 16:27:12 GMT Pac-12 Networks' Ashley Adamson catches up with Oregon's "Big 3" of Sabrina Ionescu, Ruthy Hebard and Satou Sabally to hear how they're adjusting to the new world without sports while still preparing for the WNBA Draft on April 17. They also share how they're staying hungry for basketball during the hiatus. Full Article video Sports
ic WNBA Draft Profile: Transcendent guard Sabrina Ionescu projects as top pick By sports.yahoo.com Published On :: Thu, 09 Apr 2020 20:09:19 GMT After sweeping every national player of the year award, Sabrina Ionescu is off to the WNBA level where her skills will make an instant impact — not just to her new team but the league as a whole. She averaged 17.5 points, 8.6 rebounds and 9.1 assists for the Ducks in 2019-20, rewriting her own NCAA career triple-double record and becoming the first in college basketball history with at least 2,000 points, 1,000 rebounds and 1,000 assists. Full Article video Sports
ic Inside Sabrina Ionescu and Ruthy Hebard's lasting bond on quick look of 'Our Stories' By sports.yahoo.com Published On :: Fri, 10 Apr 2020 20:26:20 GMT Learn how Oregon stars Sabrina Ionescu and Ruthy Hebard developed a lasting bond as college freshmen and carried that through storied four-year careers for the Ducks. Watch "Our Stories Unfinished Business: Sabrina Ionescu and Ruthy Hebard" debuting Wednesday, April 15 at 7 p.m. PT/ 8 p.m. MT on Pac-12 Network. Full Article video News
ic Charli Turner Thorne drops by 'Pac-12 Playlist' to surprise former player Dr. Michelle Tom By sports.yahoo.com Published On :: Thu, 16 Apr 2020 16:51:30 GMT Pac-12 Networks' Ashley Adamson speaks with former Arizona State women's basketball player Michelle Tom, who is now a doctor treating COVID-19 patients in Winslow, Arizona. Full Article video Sports
ic Dr. Michelle Tom shares journey from ASU women's hoops to treating COVID-19 patients By sports.yahoo.com Published On :: Thu, 16 Apr 2020 23:44:26 GMT Pac-12 Networks' Ashley Adamson speaks with former Arizona State women's basketball player Michelle Tom, who is now a doctor treating COVID-19 patients Winslow Indian Health Care Center and Little Colorado Medical Center in Eastern Arizona. Full Article video Sports
ic Chicago State women's basketball coach Misty Opat resigns By sports.yahoo.com Published On :: Fri, 17 Apr 2020 17:37:52 GMT CHICAGO (AP) -- Chicago State women’s coach Misty Opat resigned Thursday after two seasons and a 3-55 record. Full Article article Sports
ic UCLA's Natalie Chou on her role models, inspiring Asian-American girls in basketball By sports.yahoo.com Published On :: Tue, 05 May 2020 21:33:42 GMT Pac-12 Networks' Mike Yam has a conversation with UCLA's Natalie Chou during Wednesday's "Pac-12 Perspective" podcast. Chou reflects on her role models, passion for basketball and how her mom has made a big impact on her hoops career. Full Article video Sports
ic Natalie Chou breaks through stereotypes, inspires young Asian American girls on 'Our Stories' quick look By sports.yahoo.com Published On :: Thu, 07 May 2020 17:34:41 GMT Watch the debut of "Our Stories - Natalie Chou" on Sunday, May 10 at 12:30 p.m. PT/ 1:30 p.m. MT on Pac-12 Network. Full Article video Sports
ic The limiting behavior of isotonic and convex regression estimators when the model is misspecified By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Eunji Lim. Source: Electronic Journal of Statistics, Volume 14, Number 1, 2053--2097.Abstract: We study the asymptotic behavior of the least squares estimators when the model is possibly misspecified. We consider the setting where we wish to estimate an unknown function $f_{*}:(0,1)^{d} ightarrow mathbb{R}$ from observations $(X,Y),(X_{1},Y_{1}),cdots ,(X_{n},Y_{n})$; our estimator $hat{g}_{n}$ is the minimizer of $sum _{i=1}^{n}(Y_{i}-g(X_{i}))^{2}/n$ over $gin mathcal{G}$ for some set of functions $mathcal{G}$. We provide sufficient conditions on the metric entropy of $mathcal{G}$, under which $hat{g}_{n}$ converges to $g_{*}$ as $n ightarrow infty $, where $g_{*}$ is the minimizer of $|g-f_{*}| riangleq mathbb{E}(g(X)-f_{*}(X))^{2}$ over $gin mathcal{G}$. As corollaries of our theorem, we establish $|hat{g}_{n}-g_{*}| ightarrow 0$ as $n ightarrow infty $ when $mathcal{G}$ is the set of monotone functions or the set of convex functions. We also make a connection between the convergence rate of $|hat{g}_{n}-g_{*}|$ and the metric entropy of $mathcal{G}$. As special cases of our finding, we compute the convergence rate of $|hat{g}_{n}-g_{*}|^{2}$ when $mathcal{G}$ is the set of bounded monotone functions or the set of bounded convex functions. Full Article
ic Nonparametric confidence intervals for conditional quantiles with large-dimensional covariates By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Laurent Gardes. Source: Electronic Journal of Statistics, Volume 14, Number 1, 661--701.Abstract: The first part of the paper is dedicated to the construction of a $gamma$ - nonparametric confidence interval for a conditional quantile with a level depending on the sample size. When this level tends to 0 or 1 as the sample size increases, the conditional quantile is said to be extreme and is located in the tail of the conditional distribution. The proposed confidence interval is constructed by approximating the distribution of the order statistics selected with a nearest neighbor approach by a Beta distribution. We show that its coverage probability converges to the preselected probability $gamma $ and its accuracy is illustrated on a simulation study. When the dimension of the covariate increases, the coverage probability of the confidence interval can be very different from $gamma $. This is a well known consequence of the data sparsity especially in the tail of the distribution. In a second part, a dimension reduction procedure is proposed in order to select more appropriate nearest neighbors in the right tail of the distribution and in turn to obtain a better coverage probability for extreme conditional quantiles. This procedure is based on the Tail Conditional Independence assumption introduced in (Gardes, Extremes , pp. 57–95, 18(3) , 2018). Full Article
ic Statistical convergence of the EM algorithm on Gaussian mixture models By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Ruofei Zhao, Yuanzhi Li, Yuekai Sun. Source: Electronic Journal of Statistics, Volume 14, Number 1, 632--660.Abstract: We study the convergence behavior of the Expectation Maximization (EM) algorithm on Gaussian mixture models with an arbitrary number of mixture components and mixing weights. We show that as long as the means of the components are separated by at least $Omega (sqrt{min {M,d}})$, where $M$ is the number of components and $d$ is the dimension, the EM algorithm converges locally to the global optimum of the log-likelihood. Further, we show that the convergence rate is linear and characterize the size of the basin of attraction to the global optimum. Full Article
ic On the Letac-Massam conjecture and existence of high dimensional Bayes estimators for graphical models By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Emanuel Ben-David, Bala Rajaratnam. Source: Electronic Journal of Statistics, Volume 14, Number 1, 580--604.Abstract: The Wishart distribution defined on the open cone of positive-definite matrices plays a central role in multivariate analysis and multivariate distribution theory. Its domain of parameters is often referred to as the Gindikin set. In recent years, varieties of useful extensions of the Wishart distribution have been proposed in the literature for the purposes of studying Markov random fields and graphical models. In particular, generalizations of the Wishart distribution, referred to as Type I and Type II (graphical) Wishart distributions introduced by Letac and Massam in Annals of Statistics (2007) play important roles in both frequentist and Bayesian inference for Gaussian graphical models. These distributions have been especially useful in high-dimensional settings due to the flexibility offered by their multiple-shape parameters. Concerning Type I and Type II Wishart distributions, a conjecture of Letac and Massam concerns the domain of multiple-shape parameters of these distributions. The conjecture also has implications for the existence of Bayes estimators corresponding to these high dimensional priors. The conjecture, which was first posed in the Annals of Statistics, has now been an open problem for about 10 years. In this paper, we give a necessary condition for the Letac and Massam conjecture to hold. More precisely, we prove that if the Letac and Massam conjecture holds on a decomposable graph, then no two separators of the graph can be nested within each other. For this, we analyze Type I and Type II Wishart distributions on appropriate Markov equivalent perfect DAG models and succeed in deriving the aforementioned necessary condition. This condition in particular identifies a class of counterexamples to the conjecture. Full Article
ic Drift estimation for stochastic reaction-diffusion systems By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Gregor Pasemann, Wilhelm Stannat. Source: Electronic Journal of Statistics, Volume 14, Number 1, 547--579.Abstract: A parameter estimation problem for a class of semilinear stochastic evolution equations is considered. Conditions for consistency and asymptotic normality are given in terms of growth and continuity properties of the nonlinear part. Emphasis is put on the case of stochastic reaction-diffusion systems. Robustness results for statistical inference under model uncertainty are provided. Full Article
ic Gaussian field on the symmetric group: Prediction and learning By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT François Bachoc, Baptiste Broto, Fabrice Gamboa, Jean-Michel Loubes. Source: Electronic Journal of Statistics, Volume 14, Number 1, 503--546.Abstract: In the framework of the supervised learning of a real function defined on an abstract space $mathcal{X}$, Gaussian processes are widely used. The Euclidean case for $mathcal{X}$ is well known and has been widely studied. In this paper, we explore the less classical case where $mathcal{X}$ is the non commutative finite group of permutations (namely the so-called symmetric group $S_{N}$). We provide an application to Gaussian process based optimization of Latin Hypercube Designs. We also extend our results to the case of partial rankings. Full Article
ic Recovery of simultaneous low rank and two-way sparse coefficient matrices, a nonconvex approach By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Ming Yu, Varun Gupta, Mladen Kolar. Source: Electronic Journal of Statistics, Volume 14, Number 1, 413--457.Abstract: We study the problem of recovery of matrices that are simultaneously low rank and row and/or column sparse. Such matrices appear in recent applications in cognitive neuroscience, imaging, computer vision, macroeconomics, and genetics. We propose a GDT (Gradient Descent with hard Thresholding) algorithm to efficiently recover matrices with such structure, by minimizing a bi-convex function over a nonconvex set of constraints. We show linear convergence of the iterates obtained by GDT to a region within statistical error of an optimal solution. As an application of our method, we consider multi-task learning problems and show that the statistical error rate obtained by GDT is near optimal compared to minimax rate. Experiments demonstrate competitive performance and much faster running speed compared to existing methods, on both simulations and real data sets. Full Article
ic Parseval inequalities and lower bounds for variance-based sensitivity indices By projecteuclid.org Published On :: Tue, 05 May 2020 22:00 EDT Olivier Roustant, Fabrice Gamboa, Bertrand Iooss. Source: Electronic Journal of Statistics, Volume 14, Number 1, 386--412.Abstract: The so-called polynomial chaos expansion is widely used in computer experiments. For example, it is a powerful tool to estimate Sobol’ sensitivity indices. In this paper, we consider generalized chaos expansions built on general tensor Hilbert basis. In this frame, we revisit the computation of the Sobol’ indices with Parseval equalities and give general lower bounds for these indices obtained by truncation. The case of the eigenfunctions system associated with a Poincaré differential operator leads to lower bounds involving the derivatives of the analyzed function and provides an efficient tool for variable screening. These lower bounds are put in action both on toy and real life models demonstrating their accuracy. Full Article
ic Asymptotic properties of the maximum likelihood and cross validation estimators for transformed Gaussian processes By projecteuclid.org Published On :: Mon, 27 Apr 2020 22:02 EDT François Bachoc, José Betancourt, Reinhard Furrer, Thierry Klein. Source: Electronic Journal of Statistics, Volume 14, Number 1, 1962--2008.Abstract: The asymptotic analysis of covariance parameter estimation of Gaussian processes has been subject to intensive investigation. However, this asymptotic analysis is very scarce for non-Gaussian processes. In this paper, we study a class of non-Gaussian processes obtained by regular non-linear transformations of Gaussian processes. We provide the increasing-domain asymptotic properties of the (Gaussian) maximum likelihood and cross validation estimators of the covariance parameters of a non-Gaussian process of this class. We show that these estimators are consistent and asymptotically normal, although they are defined as if the process was Gaussian. They do not need to model or estimate the non-linear transformation. Our results can thus be interpreted as a robustness of (Gaussian) maximum likelihood and cross validation towards non-Gaussianity. Our proofs rely on two technical results that are of independent interest for the increasing-domain asymptotic literature of spatial processes. First, we show that, under mild assumptions, coefficients of inverses of large covariance matrices decay at an inverse polynomial rate as a function of the corresponding observation location distances. Second, we provide a general central limit theorem for quadratic forms obtained from transformed Gaussian processes. Finally, our asymptotic results are illustrated by numerical simulations. Full Article
ic Asymptotics and optimal bandwidth for nonparametric estimation of density level sets By projecteuclid.org Published On :: Mon, 27 Apr 2020 22:02 EDT Wanli Qiao. Source: Electronic Journal of Statistics, Volume 14, Number 1, 302--344.Abstract: Bandwidth selection is crucial in the kernel estimation of density level sets. A risk based on the symmetric difference between the estimated and true level sets is usually used to measure their proximity. In this paper we provide an asymptotic $L^{p}$ approximation to this risk, where $p$ is characterized by the weight function in the risk. In particular the excess risk corresponds to an $L^{2}$ type of risk, and is adopted to derive an optimal bandwidth for nonparametric level set estimation of $d$-dimensional density functions ($dgeq 1$). A direct plug-in bandwidth selector is developed for kernel density level set estimation and its efficacy is verified in numerical studies. Full Article
ic Assessing prediction error at interpolation and extrapolation points By projecteuclid.org Published On :: Mon, 27 Apr 2020 22:02 EDT Assaf Rabinowicz, Saharon Rosset. Source: Electronic Journal of Statistics, Volume 14, Number 1, 272--301.Abstract: Common model selection criteria, such as $AIC$ and its variants, are based on in-sample prediction error estimators. However, in many applications involving predicting at interpolation and extrapolation points, in-sample error does not represent the relevant prediction error. In this paper new prediction error estimators, $tAI$ and $Loss(w_{t})$ are introduced. These estimators generalize previous error estimators, however are also applicable for assessing prediction error in cases involving interpolation and extrapolation. Based on these prediction error estimators, two model selection criteria with the same spirit as $AIC$ and Mallow’s $C_{p}$ are suggested. The advantages of our suggested methods are demonstrated in a simulation and a real data analysis of studies involving interpolation and extrapolation in linear mixed model and Gaussian process regression. Full Article
ic Estimation of linear projections of non-sparse coefficients in high-dimensional regression By projecteuclid.org Published On :: Mon, 27 Apr 2020 22:02 EDT David Azriel, Armin Schwartzman. Source: Electronic Journal of Statistics, Volume 14, Number 1, 174--206.Abstract: In this work we study estimation of signals when the number of parameters is much larger than the number of observations. A large body of literature assumes for these kind of problems a sparse structure where most of the parameters are zero or close to zero. When this assumption does not hold, one can focus on low-dimensional functions of the parameter vector. In this work we study one-dimensional linear projections. Specifically, in the context of high-dimensional linear regression, the parameter of interest is ${oldsymbol{eta}}$ and we study estimation of $mathbf{a}^{T}{oldsymbol{eta}}$. We show that $mathbf{a}^{T}hat{oldsymbol{eta}}$, where $hat{oldsymbol{eta}}$ is the least squares estimator, using pseudo-inverse when $p>n$, is minimax and admissible. Thus, for linear projections no regularization or shrinkage is needed. This estimator is easy to analyze and confidence intervals can be constructed. We study a high-dimensional dataset from brain imaging where it is shown that the signal is weak, non-sparse and significantly different from zero. Full Article
ic Kaplan-Meier V- and U-statistics By projecteuclid.org Published On :: Thu, 23 Apr 2020 22:01 EDT Tamara Fernández, Nicolás Rivera. Source: Electronic Journal of Statistics, Volume 14, Number 1, 1872--1916.Abstract: In this paper, we study Kaplan-Meier V- and U-statistics respectively defined as $ heta (widehat{F}_{n})=sum _{i,j}K(X_{[i:n]},X_{[j:n]})W_{i}W_{j}$ and $ heta _{U}(widehat{F}_{n})=sum _{i eq j}K(X_{[i:n]},X_{[j:n]})W_{i}W_{j}/sum _{i eq j}W_{i}W_{j}$, where $widehat{F}_{n}$ is the Kaplan-Meier estimator, ${W_{1},ldots ,W_{n}}$ are the Kaplan-Meier weights and $K:(0,infty )^{2} o mathbb{R}$ is a symmetric kernel. As in the canonical setting of uncensored data, we differentiate between two asymptotic behaviours for $ heta (widehat{F}_{n})$ and $ heta _{U}(widehat{F}_{n})$. Additionally, we derive an asymptotic canonical V-statistic representation of the Kaplan-Meier V- and U-statistics. By using this representation we study properties of the asymptotic distribution. Applications to hypothesis testing are given. Full Article
ic Adaptive estimation in the supremum norm for semiparametric mixtures of regressions By projecteuclid.org Published On :: Thu, 23 Apr 2020 22:01 EDT Heiko Werner, Hajo Holzmann, Pierre Vandekerkhove. Source: Electronic Journal of Statistics, Volume 14, Number 1, 1816--1871.Abstract: We investigate a flexible two-component semiparametric mixture of regressions model, in which one of the conditional component distributions of the response given the covariate is unknown but assumed symmetric about a location parameter, while the other is specified up to a scale parameter. The location and scale parameters together with the proportion are allowed to depend nonparametrically on covariates. After settling identifiability, we provide local M-estimators for these parameters which converge in the sup-norm at the optimal rates over Hölder-smoothness classes. We also introduce an adaptive version of the estimators based on the Lepski-method. Sup-norm bounds show that the local M-estimator properly estimates the functions globally, and are the first step in the construction of useful inferential tools such as confidence bands. In our analysis we develop general results about rates of convergence in the sup-norm as well as adaptive estimation of local M-estimators which might be of some independent interest, and which can also be applied in various other settings. We investigate the finite-sample behaviour of our method in a simulation study, and give an illustration to a real data set from bioinformatics. Full Article
ic Exact recovery in block spin Ising models at the critical line By projecteuclid.org Published On :: Thu, 23 Apr 2020 22:01 EDT Matthias Löwe, Kristina Schubert. Source: Electronic Journal of Statistics, Volume 14, Number 1, 1796--1815.Abstract: We show how to exactly reconstruct the block structure at the critical line in the so-called Ising block model. This model was recently re-introduced by Berthet, Rigollet and Srivastava in [2]. There the authors show how to exactly reconstruct blocks away from the critical line and they give an upper and a lower bound on the number of observations one needs; thereby they establish a minimax optimal rate (up to constants). Our technique relies on a combination of their methods with fluctuation results obtained in [20]. The latter are extended to the full critical regime. We find that the number of necessary observations depends on whether the interaction parameter between two blocks is positive or negative: In the first case, there are about $Nlog N$ observations required to exactly recover the block structure, while in the latter case $sqrt{N}log N$ observations suffice. Full Article
ic Efficient estimation in expectile regression using envelope models By projecteuclid.org Published On :: Thu, 23 Apr 2020 22:01 EDT Tuo Chen, Zhihua Su, Yi Yang, Shanshan Ding. Source: Electronic Journal of Statistics, Volume 14, Number 1, 143--173.Abstract: As a generalization of the classical linear regression, expectile regression (ER) explores the relationship between the conditional expectile of a response variable and a set of predictor variables. ER with respect to different expectile levels can provide a comprehensive picture of the conditional distribution of the response variable given the predictors. We adopt an efficient estimation method called the envelope model ([8]) in ER, and construct a novel envelope expectile regression (EER) model. Estimation of the EER parameters can be performed using the generalized method of moments (GMM). We establish the consistency and derive the asymptotic distribution of the EER estimators. In addition, we show that the EER estimators are asymptotically more efficient than the ER estimators. Numerical experiments and real data examples are provided to demonstrate the efficiency gains attained by EER compared to ER, and the efficiency gains can further lead to improvements in prediction. Full Article
ic Nonparametric false discovery rate control for identifying simultaneous signals By projecteuclid.org Published On :: Thu, 23 Apr 2020 22:01 EDT Sihai Dave Zhao, Yet Tien Nguyen. Source: Electronic Journal of Statistics, Volume 14, Number 1, 110--142.Abstract: It is frequently of interest to identify simultaneous signals, defined as features that exhibit statistical significance across each of several independent experiments. For example, genes that are consistently differentially expressed across experiments in different animal species can reveal evolutionarily conserved biological mechanisms. However, in some problems the test statistics corresponding to these features can have complicated or unknown null distributions. This paper proposes a novel nonparametric false discovery rate control procedure that can identify simultaneous signals even without knowing these null distributions. The method is shown, theoretically and in simulations, to asymptotically control the false discovery rate. It was also used to identify genes that were both differentially expressed and proximal to differentially accessible chromatin in the brains of mice exposed to a conspecific intruder. The proposed method is available in the R package github.com/sdzhao/ssa. Full Article
ic Non-parametric adaptive estimation of order 1 Sobol indices in stochastic models, with an application to Epidemiology By projecteuclid.org Published On :: Wed, 22 Apr 2020 04:02 EDT Gwenaëlle Castellan, Anthony Cousien, Viet Chi Tran. Source: Electronic Journal of Statistics, Volume 14, Number 1, 50--81.Abstract: Global sensitivity analysis is a set of methods aiming at quantifying the contribution of an uncertain input parameter of the model (or combination of parameters) on the variability of the response. We consider here the estimation of the Sobol indices of order 1 which are commonly-used indicators based on a decomposition of the output’s variance. In a deterministic framework, when the same inputs always give the same outputs, these indices are usually estimated by replicated simulations of the model. In a stochastic framework, when the response given a set of input parameters is not unique due to randomness in the model, metamodels are often used to approximate the mean and dispersion of the response by deterministic functions. We propose a new non-parametric estimator without the need of defining a metamodel to estimate the Sobol indices of order 1. The estimator is based on warped wavelets and is adaptive in the regularity of the model. The convergence of the mean square error to zero, when the number of simulations of the model tend to infinity, is computed and an elbow effect is shown, depending on the regularity of the model. Applications in Epidemiology are carried to illustrate the use of non-parametric estimators. Full Article