A protein shredder that occurs in cell membranes of brain cells apparently also indirectly regulates the fat metabolism. The shredder, known as gamma-secretase, is considered a possible target for drugs against cancer and Alzheimer's disease. However, the results suggest that such agents may have long-range effects that need to be watched closely.

Follow our live coronavirus updates HERE Coronavirus: the symptoms

Follow our live coronavirus updates HERE Coronavirus: The symptoms

In today's Diary: Rishi Sunak's secret weapon / A question setter's worst nightmare / Billy Porter on the piece of art he wants most / Liberal Tories hope for immigration change

Follow our live Covid-19 updates HERE Coronavirus: The symptoms

Coronavirus: the symptoms Read our LIVE updates on the coronavirus here

Donald Trump has unveiled a phased approach reopening the US economy which has been hit by the coronavirus pandemic.

Follow our live coronavirus updates HERE

The first coronavirus patients to be successfully treated at London's new NHS Nightingale London are returning home to their loved ones.

Officials in San Clemente draw line in the sand at local park after weeks of rule-breaking by unruly skateboarders

Billionaire Sir Richard Branson today warned Virgin Atlantic will need financial aid from the Government in order to survive the coronavirus crisis as he defended himself amid backlash over a bailout request.

Doctors performed an emotional rendition of Ave Maria to celebrate the recovery of a fellow nurse from the coronavirus.

Memorial services will be held in Australia and New Zealand this week to mark Anzac Day.

Matt Hancock has praised Muslims across the UK for making changes to how they mark Ramadan due to the coronavirus lockdown.

Services around the world have been disrupted due to the coronavirus crisis

All mail sent this week in the UK will be stamped with a special postmark to celebrate the 100th birthday of NHS fundraiser Captain Tom Moore.

The Duke and Duchess of Cambridge have marked their ninth wedding anniversary with a throwback photo of their glittering wedding day.

Boris Johnson and Carrie Symonds have welcomed the arrival of their first child together.

Donald Trump has accused the World Health Organisation (WHO) of being a "pipe organ" for China during the coronavirus pandemic.

A pioneering heart surgeon and a dedicated nurse who volunteered to treat Covid-19 patients are among the latest Londoners to die with the virus.

Boris Johnson has hailed Captain Tom Moore a "point of light" in the lives of the nation as he led tributes to the war veteran on his 100th birthday.

The nine-year-old was inspired by hero fundraiser Captain Tom Moore's £30 million fundraiser

Rain will batter all four corners of the country for periods on both Saturday and Sunday and temperatures will plummet following the sunniest ever April.

A new photograph of Princess Charlotte has been released by Kensington Palace to mark her fifth birthday.

The UK is braced for a wet weekend with sunny spells as temperatures drop ahead of the May Bank Holiday.

The Duke and Duchess of Sussex will today celebrate the first birthday of their son Archie while under lockdown in the US.

The Government has cautioned the public against overexcitement at the prospect of the coronavirus lockdown being eased.

The mundanity of coronavirus lockdown life is being celebrated in a photography exhibition to raise money for frontline workers.

Victory in Europe Day, or VE Day, marked the end of the Second World War in Europe, when Germany surrendered to the Allied armies.

Celebrations kick off tomorrow morning!

This year is the 75th anniversary of Victory in Europe (VE) Day, which marked the end of the Second World War on the continent.

The nation is preparing to celebrate the 75th anniversary of Victory in Europe (VE) Day , with the Queen set to make a historic address to mark the occasion.

Wales has taken the first step to easing lockdown by relaxing exercise rules and reopening some libraries, tips and garden centres.

The Queen's memories of her VE Day celebrations have been shared by Buckingham Palace to mark the 75th anniversary of the end of the war in Europe.

From samba to jazz and house, the DJ and founder of radio station Worldwide FM picks 10 tracks to transport you to Brazil

Originally released in 1980, this funky track from solo artist Cristina Camargo is pure “80s vibes”, Peterson says. “I’ve been loving this boogie tune, produced by Lincoln Olivetti and Robson Jorge, of late. It lifts the mood every time.” Olivetti and Jorge crafted Rio’s early-80s boogie sound, and produced classic albums by Brazilian disco legends in the mid-70s. “It reminds me of line dancing in Rio, particularly on a Sunday afternoon in Lapa, where sound systems play a mixture of this and classic British 80s cuts by the likes of Lisa Stansfield and Soul II Soul – very obscure!”

The third time's the charm for the Allen Institute for Brain Science's 3-D atlas of the mouse brain. Version 3 of the atlas, known as the Allen Mouse Brain Common Coordinate Framework or CCFv3, is the subject of a research paper published today in the journal Cell. It builds on a partial brain map that focused on the mouse cortex and was released in 2016. Previous versions of the atlas were rendered with lower-resolution 3-D maps. The latest high-resolution maps are fine enough to pinpoint the locations of individual brain cells — which is crucial for interpreting datasets that contain thousands… Read More

Fighter planes soared in blue skies above towns and cities across the UK to mark the VE Day anniversary

It’s amazing what happens if you just get out there, writes Ernie Schramayr.

Here’s to the fools who dream — and to the mess they make. Three years ago, Starline Tours dreamed up a branded tour of the locations in “La La Land,” the musical starring Ryan Gosling and Emma Stone. But now, the Hollywood tour company has ended up in litigation. Lionsgate, which produced the film, filed […]

Tracy Brabin has said she will have to change her phone number after it was inadvertently shown on screen while she was being interviewd on ITV's This Morning.

Priti Patel had defended Boris Johnson after he was branded a "racist" by rapper Dave on stage at the 2020 Brit Awards.

With hospitals and cemeteries overwhelmed by the coronavirus, the mayor of Manaus, Brazil's hardest hit city, has appealed to world leaders, including President Trump, for help.

Russian President Vladimir Putin had celebrations to mark victory in WWII and a constitutional vote to keep him in power till 2036 planned for this spring. But the pandemic has canceled both events.

"Today, 75 years later, we are forced to commemorate alone, but we are not alone!" Germany's President Frank-Walter Steinmeier says, celebrating international unity in the post-war era.

The Coast Guard is increasing its presence in the Caribbean in an attempt to forestall a potential COVID-19-inspired surge in illegal migration and human smuggling from the region.

To mark our 175th anniversary year, we feature a different front page each week from past editions of the Ottawa Citizen.

From the #MetGalaChallenge to high fashion Twitter's Met Gala