K-12 teachers are faced with a question many likely thought they'd never have to ask: How often during the school day do my students need to see me and when?

FIVE new nursery extensions being built at schools across Edinburgh have been thrown into doubt after the company building the facilities entered administration.

In the face of well-funded opposition to organized labor, teachers will not be silenced, writes NEA President Lily Eskelsen García.

As superintendents, we must make the system work for all students—however socially, politically, and professionally dangerous it may be, writes Demond A. Means.

Captain Flecha completed his hat-trick in the 88th minute as – for the second time in as many Group A games – Lisboa repeatedly came from behind to draw.

Poland's Dolny Śląsk came from behind to beat hosts Bavaria 3-2 for the amateur title in a final of five penalties.

Dolny Śląsk beat hosts Bavaria 3-2 in a thrilling final to become only the second two-time winners.

Less than 20 percent of respondents to a new CoSN survey marked any items on a list of cybersecurity threats as "high-risk" from their perspective.

LIKE many of your readers, I would imagine, I am a fairly enthusiastic armchair football supporter with no real club affiliation.

A five-part series on mistakes made by school administrators is wrapped-up today with commentaries from Dr. Lynell Powell, Stuart Ablon, Alisha Pollastri, Diane Mora and many comments from readers

IT was impossible to escape a heart-sinking feeling this week when reading reports that a senior UK Government source believed people were “addicted” to the furlough scheme.

Two high-powered N.Y. officials have put out a blueprint for overhauling teaching in the state, aiming for more-coherent policies for the profession.

Over the last two decades, STEM teachers have become increasingly more likely to be female and well-qualified.

Pro licence students from the Azeri, Estonian, Russian and Welsh national associations have visited UEFA for the latest coach education exchange programme seminar.

Talented young referees and international women referees are in Nyon this week for the latest courses in UEFA's referee development programme.

Former Swiss internationals including Pascal Zuberbühler helped turn the UEFA European Women's Under-17 Championship semi-finals into a family-orientated festival of football.

A Japanese man's heart changes during the few days an OM team and a group of volunteers help restore his home.

Infantile hypertrophic pyloric stenosis incidence varies over different regions and time periods. Recently, a decline was reported in the United States, Sweden (concurrent with a decline in sudden infant death syndrome), Scotland, and Denmark. The etiology remains unclear; therefore, epidemiologic data are valuable.

A decline in the incidence of infantile hypertrophic pyloric stenosis in Germany from 2000 to 2008 was noted but with wide regional variations. The regional distribution of infantile hypertrophic pyloric stenosis was different from that of sudden infant death syndrome. (Read the full article)

Male circumcision reduces risk of HIV acquisition in men by 60% and is associated with other health benefits. Compared with adult circumcision, infant male circumcision is safer, less expensive, and represents a cost-saving intervention for HIV prevention in many settings.

IMC is little known in East Africa and is not routinely practiced. This is the first study to assess acceptability and uptake of IMC in East Africa among parents who were actually offered the procedure. (Read the full article)

Pharmacologic treatment with sapropterin dihydrochloride (6R-tetrahydrobiopterin; BH4) has been an effective option for some phenylketonuria patients since its approval by the US Food and Drug Administration in 2007 and the European Medicines Agency in 2008.

This retrospective multicenter study revealed the long-term effects of sapropterin on metabolic control, dietary tolerance, and the outcome of BH4-responsive phenylketonuria patients harboring specific phenotypes and genotypes. It also confirmed that the minor adverse events disappeared by lowering the dose. (Read the full article)

Lisa Dahlkvist's penalty won Sweden an Olympic shoot-out against favourites the United States, and Germany forged on, but France did not make it to the last four.

The Olympic women's football final will be an all-European affair after Sweden ousted hosts Brazil on penalties and Germany beat Canada in Tuesday's semi-finals.

History overwhelmingly favours Germany against Sweden on Friday, but in Pia Sundhage, Sweden are led by a coach bidding for a third successive Olympic gold.

Silvia Neid has won it all as a player and coach ... nearly. Only an Olympic gold has eluded her – on Friday she can end that wait in her final game as Germany coach.

Silvia Neid brought down the curtain on her 11-year reign as Nationalelf coach triumphantly as Germany overcame a spirited Sweden side 2-1 to win their first Olympic title.

It had been 19 years since Germany lost a qualifier but Iceland ended that run in stunning style with a 3-2 away win that finished some incredible runs by the twice world champions.

At Battle High School in Columbia, Mo., students in geometry class have swapped their compasses and protractors for hammers and hard hats. And they're doing it for a good cause.

Due to markets and festivals closing until the end of June, a Fin24 reader will have no source of income and wants to know if there will be a payment holiday period. A debt expert responds.

In rural Kentucky, teachers and students are awarded innovation grants to solve a challenge facing their community or classroom.

The Sony Cyber-shot DSC-RX100 VII point-and-shoot is a modest update to the RX100 VI, offering better autofocus and video stabilization for a bit more money.

Sony reinvented the premium point-and-shoot camera in 2012 with the RX100. It's continued to build out the series, but has also kept older models on sale. We're here to help you find the right one to suit your needs.

The Sony E 16-50mm F3.5-5.6 PZ OSS is a low-cost zoom that puts more emphasis on size and weight than absolute image quality.

The Sony a6100 is a compact, speedy camera with strong image quality and excellent autofocus. Family photographers will love it, but enthusiasts may want to consider the a6400 instead.

In a country wasted by conflict, OM brings healing to Angola’s people by strengthening local churches, training leaders and caring for children at risk.

The quinoline MK-571 is the most commonly used inhibitor of multidrug resistance protein-1 (MRP-1) but was originally developed as a cysteinyl leukotriene receptor 1 (CysLTR1) antagonist. While studying the modulatory effect of MRP-1 on anti-hepatitis C virus (HCV) direct acting-antivirals (DAA) efficiency, we observed an unexpected anti-HCV effect of compound MK-571 alone. This anti-HCV activity was characterized in Huh7.5 cells stably harboring a subgenomic genotype 1b replicon. A dose-dependent decrease of HCV RNA levels was observed upon MK-571 administration, with an EC₅₀ of 9±0.3 μM and a maximum HCV RNA level reduction of approximatively 1 Log₁₀. MK-571 also reduced the replication of the HCV full-length J6/JFH1 model in a dose-dependent manner. However, probenecid and apigenin homodimer (APN), two specific inhibitors of MRP-1, had no effect on HCV replication. In contrast, the CysLTR1 antagonists SR2640 increased HCV-SGR RNA levels in a dose-dependent manner, with a maximum increase of 10-fold. In addition, a combination of natural CysLTR1 agonist (LTD4) or antagonists (zafirlukast, cinalukast, and SR2640) with MK-571 completely reversed its antiviral effect, suggesting its anti-HCV activity is related to CysLTR1 rather to MRP-1 inhibition. In conclusion, we showed that MK-571 inhibits HCV replication in hepatoma cell cultures by acting as a CysLTR1 receptor antagonist, thus unraveling a new host-virus interaction in the HCV life cycle.

Despite the worldwide re-emergence of the chikungunya virus (CHIKV) and the high morbidity associated with CHIKV infections, there is no approved vaccine or antiviral treatment available. We here aim to identify the target of a novel class of CHIKV inhibitors i.e. CHVB series. CHVB compounds inhibit the in vitro replication of CHIKV isolates with 50% effective concentrations in the low micromolar range. A CHVB-resistant variant (CHVB^res) was selected that carried two mutations in the gene encoding nsP1 (responsible for viral RNA capping), one mutation in nsP2 and one mutation in nsP3. Reverse genetics studies demonstrated that both nsP1 mutations were necessary and sufficient to achieve ~18-fold resistance, suggesting that CHVB targets viral mRNA capping. Interestingly, CHVB^res was cross-resistant to the previously described CHIKV capping inhibitors from the MADTP series, suggesting they share a similar mechanism of action. In enzymatic assays, CHVB inhibited the methyltransferase and guanylyltransferase activities of alphavirus nsP1 proteins. To conclude, we identified a class of CHIKV inhibitors that targets the viral capping machinery. The potent anti-CHIKV activity makes this chemical scaffold a potential candidate for CHIKV drug development.

Benetech, a Palo Alto, Calif. based software company, is embarking on is third 5-year award with the U.S. Department of Education to create books for students with print disabilities.

Germany's Shekiera Martinez, at 16, has written herself into UEFA's record books by scoring nine goals in a final tournament.

Germany pipped the Netherlands on penalties to make it seven titles in the 12 #WU17EURO seasons.

Many teachers scrapped their lesson plans on Monday and gave their students space to talk about Kobe Bryant.

A signature program at Penn State Greater Allegheny, implemented to give students, faculty and staff the digital skills to communicate, solve problems and create new knowledge, is front and center in the University’s remote learning period.

Dedication to student print journalism paid off for several Penn State Greater Allegheny student reporters and designers.

Getting ready for the big game? There are plenty of options, even if you're abroad. Here's how to watch in the states or bypass region blocking with a VPN to watch the Super Bowl.

The Walkman NW-ZX2 has Bluetooth compatibility, 128GB of internal storage, and a big price tag.

The company also announced a second Walkman, a pair of headphones, and an amplifier.

For a limited time, you can get a Dell Optiplex 9020 Micro computer for as low as $269.99 with a full 1-year warranty as part of an off-lease refurbished sale from the PCMag Shop.

You don't have to fork over a bunch of cash to get a bunch of storage. PNY flash drives, SD cards, and portable drives are on sale at Amazon, with prices starting as low as $5.84.

The Z8H 8K LED vibrates the frame of the television to emit audio and give the impression that the sound is coming directly from the screen itself.

That free Echo Dot will let you launch apps, search for titles, and switch inputs on your TV with just your voice.

In our review, we called this TV 'among the brightest we've tested.' It comes in five different sizes, all of which are currently between 18 and 39 percent off at Amazon.